LOCUS       NM_172737               6058 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus shisa family member 7 (Shisa7), transcript variant 1,
            mRNA.
ACCESSION   NM_172737
VERSION     NM_172737.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6058)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6058)
  AUTHORS   Wu,K., Han,W., Tian,Q., Li,Y. and Lu,W.
  TITLE     Activity- and sleep-dependent regulation of tonic inhibition by
            Shisa7
  JOURNAL   Cell Rep 34 (12), 108899 (2021)
   PUBMED   33761345
  REMARK    GeneRIF: Activity- and sleep-dependent regulation of tonic
            inhibition by Shisa7.
REFERENCE   3  (bases 1 to 6058)
  AUTHORS   Han,W., Li,J., Pelkey,K.A., Pandey,S., Chen,X., Wang,Y.X., Wu,K.,
            Ge,L., Li,T., Castellano,D., Liu,C., Wu,L.G., Petralia,R.S.,
            Lynch,J.W., McBain,C.J. and Lu,W.
  TITLE     Shisa7 is a GABAA receptor auxiliary subunit controlling
            benzodiazepine actions
  JOURNAL   Science 366 (6462), 246-250 (2019)
   PUBMED   31601770
  REMARK    GeneRIF: data indicate that Shisa7 regulates GABAAR trafficking,
            function, and pharmacology and reveal a previously unknown
            molecular interaction that modulates benzodiazepine action in the
            brain
REFERENCE   4  (bases 1 to 6058)
  AUTHORS   Schmitz,L.J.M., Klaassen,R.V., Ruiperez-Alonso,M., Zamri,A.E.,
            Stroeder,J., Rao-Ruiz,P., Lodder,J.C., van der Loo,R.J.,
            Mansvelder,H.D., Smit,A.B. and Spijker,S.
  TITLE     The AMPA receptor-associated protein Shisa7 regulates hippocampal
            synaptic function and contextual memory
  JOURNAL   Elife 6, e24192 (2017)
   PUBMED   29199957
  REMARK    GeneRIF: Thus, Shisa7 is a bona-fide AMPA receptor modulatory
            protein affecting channel kinetics of the receptors, necessary for
            synaptic hippocampal plasticity, and memory recall.
            Erratum:[Elife. 2018 May 04;7:e36711. doi: 10.7554/eLife.36711.
            PMID: 29726811]
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6058)
  AUTHORS   Farrow,P., Khodosevich,K., Sapir,Y., Schulmann,A., Aslam,M.,
            Stern-Bach,Y., Monyer,H. and von Engelhardt,J.
  TITLE     Auxiliary subunits of the CKAMP family differentially modulate AMPA
            receptor properties
  JOURNAL   Elife 4, e09693 (2015)
   PUBMED   26623514
  REMARK    GeneRIF: This study indicates that AMPAR function is very precisely
            controlled by the cell-type specific expression of the CKAMP family
            members 39, 52 and 59.
            Erratum:[Elife. 2018 Oct 11;7:e42543. doi: 10.7554/eLife.42543.
            PMID: 30306889]
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ120465.1, AC162034.6, AK085127.1 and CF538627.1.
            
            On Feb 14, 2009 this sequence version replaced NM_172737.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KU707906.1, SRR17784644.927115.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849385,
                                           SAMN01164131 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-504               CJ120465.1         3-506
            505-851             AC162034.6         180615-180961       c
            852-3085            AK085127.1         74-2307
            3086-5674           AC162034.6         170380-172968       c
            5675-6058           CF538627.1         1-384
FEATURES             Location/Qualifiers
     source          1..6058
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.79 cM"
     gene            1..6058
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /note="shisa family member 7"
                     /db_xref="GeneID:232813"
                     /db_xref="MGI:MGI:3605641"
     exon            1..92
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /inference="alignment:Splign:2.1.0"
     exon            93..927
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1082
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1133
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1283
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..6007
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3086
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /note="major polyA site"
     polyA_site      3420
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
     regulatory      5987..5992
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
                     /note="hexamer: AATAAA"
     polyA_site      6007
                     /gene="Shisa7"
                     /gene_synonym="ckamp59"
ORIGIN      
        1 gggctggcag acacgcgctc gctctgccta ccctggctgg cccccacgct gccacccccg
       61 attccctgaa ggtcccgcat ccggaaagtg agtcctccct tcgtaaaaac ttctgtatcc
      121 cctcctccgt ccccgccgat cctttctttt ctcctgctga gcccctctct cgtcgctccc
      181 tttgtcctcc cctcccaccg ctgcaattcg gctccgggat ccgcagcctg gcgtcccggt
      241 gtgcaccatg ccggccctgc tgctgctcgg gaccgtcgcg ctgctagcct ccgcagcggg
      301 cccggcgggg gcgcgcccat ccaacgacac aagctcagtg gccccgggcc cgctgcccgc
      361 gctactcgcg cacctgcggc gcttgaccgg ggctctggcg ggcggcggga gcgcggcagg
      421 taccagcgcc aacgccacca agaccagccc cgcgagtggc acgggcgcag cggcacgggc
      481 gcctcctccg gccgagctct gccatggcta ctacgatgtc atgggccagt acgacgccac
      541 cttcaactgc agcaccggct cctaccgctt ctgttgtggc acctgccact accgtttctg
      601 ctgcgagcac cgccacatgc gcctggcgca ggcctcctgc tccaactacg acacgccacg
      661 ctgggccacc acgcccccgc cgctggctgg aggcgccggg ggcgctgggg gtgcgggtgg
      721 gggaccaggg ccgggccagg cagggtggct ggaagggggc cgggccgggg gcgctggggg
      781 acgtggggga gagggcccag ggggcagcac agcctacgtg gtgtgcggag tcatcagttt
      841 cgccctggcg gtgggcgtcg gtgccaaagt ggccttcagc aaggcgtcac gtgcacccag
      901 ggcgcaccgg gagatcaacg tgcccagagc tctcgtggat attctcaggc atcaagcagg
      961 acctgcaacc cgcccggacc gggccagaag cagttctctg accccagggc tgggaggccc
     1021 agacagcatg gccccaagga cacccaagaa cctttacaac accatgaagc cctccaacct
     1081 cgataacctg cactacaacg tcaacagccc caagcaccac gccgccacac tggactggcg
     1141 tgctatgccg ccgcccagcc cctccctgca ctactccaca ctatcctgct cccgatcctt
     1201 ccacaacctc tctcatcttc ccccgtccta tgaggctgct gtgaaatcag aactgaatcg
     1261 atactcttcc ctcaagagac tggctgagaa agatctggat gaagcctacc tgaagcgcag
     1321 acaactggag atgccgcgcg gaacgctgcc cttgcatgca ctccggcggc ctggcactgg
     1381 aggtggctac cgtatggatg gctggggtgg ccctgaggag ctgggcctgg caccagcacc
     1441 caacccacgg cgtgttatgt cccaggagca ccttctgggt gatggtagcc gagcttcccg
     1501 ctatgagttc acgttgcctc gagcgcgcct ggtgtctcag gaacacctgc tgctgtcctc
     1561 acctgaggcg cttcgccaga gtcgcgagca cctgctgtca cccccacgaa gtcctgcact
     1621 gcccccagat cccaccaccc gggccagcct ggctgcctca cactccaacc tgctgctagg
     1681 gcctgggggc ccccccacac ccctgcatgg gttgcctccg tcaggcctgc atgcccacca
     1741 tcaccatgcc cttcatggct ctcctcagcc agcctggatg tctgatgcgg gcgggggtgg
     1801 gggcacactg gcccgcaggc cacccttcca gcgccagggc accctggagc agctgcagtt
     1861 cattcctggg caccacctgc cccagcacct gcgcactgcc agcaagaacg aagtgactgt
     1921 ctgaggcccg gtggagtgct gggggctgtg gcttccgagg cccccttctc ccagcccaga
     1981 tctccattac aaggcttatc atacacacca aggctctgag accagatggg cccttggacc
     2041 ggagaccacg cctccttttg ggatgttaca gtagatgaga tctctccttt tactttgtca
     2101 ctgtttgaac caaggcctcc ctcccatgat gtcatcccag aggaaggagg cctgtatatg
     2161 aggtcattgc tagcaaatat gtctgtgttt tatgatgttg tttgcaggga ctaaacctcc
     2221 ttcctatgag gtcaccacag aggaagagcc ctgcctgagg tcatcactag aggctatgtc
     2281 cattttgcat gacatcacca cagaaactcc tttcctgtga tgtcactacg acaatgcctt
     2341 gtcccatccc atcatcccta caaacaaaaa tttcttcctg cgtgtcacta cagagacaag
     2401 tctcacactt cttgacactt gttgacatca tcctgactga gcaccaaggc ctcttgcaat
     2461 tatcatcaca ggaaaaatgt ttctctgcca tggagaagat agctccattc catgatgcca
     2521 ccactacaga caaagccatt ttcctgggac acatcgcagt ggactacgcc ctgccagtta
     2581 tgtcctcact aacaattagg cctcctttcc acaatactat cacaggactt tgcctccctc
     2641 ctgtgatgcc atcaccagaa taggtgcctt gcccaatggc gccatcacag ggactgtgcc
     2701 tcttcatgtg atgtcattac cagaaatgac cacctgttct tgggacttct ccagagtgag
     2761 gcccttctgt ggtgtgacca ccagttacca cccacttgga aatgacacca ggagacacct
     2821 ctatcgctgt gccatgtcgt gagaaagttg ggcatgtgta gcccaaggcc acctgggaag
     2881 aggccagaga aagtaacctg tcctgagatg tcatgagggc gtcagcacta gggatactag
     2941 ggtctttcta taggatgctg ggggtgatgc cctctattgc ttggacatca tcatagagtg
     3001 cttccttctc agaggtgttc cccactctag atgaccaaca gtagtgactg cataatgatt
     3061 gtgtcatcag agtccttaag tccctatagc tgagctctgt gcttctttct ttgcgtgacc
     3121 ccaggggcat agccaacagg atgtctacta gccccagtaa aggcagactg ggcctgtgca
     3181 gtgagccctg gggatgcagt gagccctggg gacggcaccc atggatgagc ttcagctcca
     3241 cagccgctct gatccacagg gctgctaaag tcctgggact caagggtgag ccaaaggatg
     3301 gcatcacttc tttctgccat atctaaagac atcagctctc aacacagtcc ccatctctat
     3361 tggaggggaa gggttagggt atatgtgctg ttgaccttgc caatgacatc atcaatgcca
     3421 cccagtgtcc tcctttcatg atggcatagc agttggggtc caatgttaac tgtgtcattt
     3481 cccagaattc catgactcac ctcaattacc atatcaactt ccaggcatta tcaccattaa
     3541 tggcatcatc attgcctccc aagatccctc ccaaccatgg tgtcatcatt tcccagggtc
     3601 caaacaacac atcatcatga tgtcccagga tccactatgt cctcattgct tcccagaatc
     3661 cttcacaaca tgctcacctc atcacctccc agcatccatc acagccaggg ggtcttcatc
     3721 tcccagcaat cacaaccata cagtcctcac catctcccag atggtgagat ccatcagaac
     3781 cacactgtcc tcatctctca ggacttgtta ggactgatag agccagagtc tctcgtgact
     3841 ccatataatt gcagtgtcac ctcccaggac ccactttagc catgtcttca tgtctcagta
     3901 gccatcatag ctatgatgtc accacttcat aaaatccact ccaactgtgg tgtccctgga
     3961 ttcttgtgac catgtatcat cacatcccag tatccatcta atagtgtcac aagtatcata
     4021 tacaatgagc atctatgagg accatcattc tgtcacctcc ctagacacat cagtcatgtc
     4081 ctatcacgac tcatcaggat ttactgtaac tgtggtgcca tcacctccaa gcagccataa
     4141 tagccaacag tgtcttcatt ctccaggacc tacttcaacc ccagtgtctc catggcttag
     4201 ggtctaccat aatcacagtt gtcatcacct ccctggaccc atggcaacaa taatgttatc
     4261 atttccagag tgtacttcag cgatggtgcc atcatcctct cccagaatcc atgtaaaacc
     4321 gtgtgtcctc atcttctagg acccgtggca attgtgtgcc atctaccagg acccatcatc
     4381 ttagggtcca aatgttgtga caggctatat ttcagttgtc ctctggggtc tcatggcatt
     4441 tacagttcct ccctttaggg gaaccagcac aacaggccat ttcccattcc ctccaatgga
     4501 ctagggtgga gccagctgcc tcctctgata atgtcacccc actctgtccc ttcttaatgt
     4561 gtcactgcct cattcctgat ccgaatagat acctggatca gcttcaccta cagacttggc
     4621 cttggcaagc ctccttccac tcactggtga gtgcatctta actcttcttg gattaccact
     4681 gtcccttgcc cagccatctg atcggtgaca gggtcatctt ggtgacctct ccacagcagc
     4741 agcagagggg gagcttccca gcccttagat ggcatcactg ccctaaccca ctccatttct
     4801 ggtacttggt cccaaccagg atcagaactt gctggcttgg gccatgctct gtctagagag
     4861 gatgtaggag atgccacagc tgataaacca cccgctggcc tattcctgga gtatgtatat
     4921 ctgagagcaa tggcccctgc taccttcacc tgaaaaggcc aagggtgctc ctttgcctct
     4981 ttccctaata taccagggag tgagtaccca ggggcttcag gaagtccctg acacccagtg
     5041 cacaatcttt tcctgccaca cccagttctc tgtacatata gccatgtttc aggggggcgg
     5101 ccattcccca ctcttaaagg gctacatgcc cccctcccag cccctatggc aaggagaggg
     5161 gctcttctcc ctcctctggg ccgccctctc cctcttatgt ctccctcccc ccaccaaata
     5221 ttggcccctg tggccatccc ttcttgccca gagcctggat gggatagatg gtaacaggct
     5281 ctcaccatgc tgaggaaagt agggagttac caccaatctt cctaaatgcc agcaccaggt
     5341 tttcggcctc ccaactaata gatgctccat gggctccgca tccattctag ggcctccctt
     5401 caagtgtgct taacactccc atggaacaca cagctttctc caagccctgg agaggttcag
     5461 gggctttcag cttttgtttg cccactctct ctttcccttc atccctcccc aaacctgaat
     5521 tccttccttc ctgggatctg ccctcacccc agcctccacc ctccacctgc ctgaccctga
     5581 agtcttgacc tcttatttca ataaagccat agtggggaga ggtcttgagg gtgggccagc
     5641 aggccctgtt ctgctcatcc cccaccatca ccacgatgct tccagaattg ggacctggcc
     5701 ttctgagtct tcccctcccc acccccaccc ctgctcccca ataaacacaa atacacatag
     5761 gcagggtgtg cccatgcagg aaagctccct tctggctggg ggctgcagag ggggtgtcag
     5821 agacaagatc aaagtgccac accagaggtt cctcaggcct ctgaacccca ttcttactcc
     5881 cctccccaca cttccttcca gtgctggact caccttcatc ttcctggtga ggacagcaaa
     5941 aggagcaggc acttggctgg gggtggggtg ttggtttttg ttttggaata aacagctgtt
     6001 ttcctgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
