LOCUS       NM_001415764            8151 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus shisa family member 6 (Shisa6), transcript variant 1,
            mRNA.
ACCESSION   NM_001415764
VERSION     NM_001415764.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8151)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8151)
  AUTHORS   Nakagawa,T., Jorg,D.J., Watanabe,H., Mizuno,S., Han,S., Ikeda,T.,
            Omatsu,Y., Nishimura,K., Fujita,M., Takahashi,S., Kondoh,G.,
            Simons,B.D., Yoshida,S. and Nagasawa,T.
  TITLE     A multistate stem cell dynamics maintains homeostasis in mouse
            spermatogenesis
  JOURNAL   Cell Rep 37 (3), 109875 (2021)
   PUBMED   34686326
REFERENCE   3  (bases 1 to 8151)
  AUTHORS   Peter,S., Urbanus,B.H.A., Klaassen,R.V., Wu,B., Boele,H.J.,
            Azizi,S., Slotman,J.A., Houtsmuller,A.B., Schonewille,M.,
            Hoebeek,F.E., Spijker,S., Smit,A.B. and De Zeeuw,C.I.
  TITLE     AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic
            Excitability and Procedural Memory Formation
  JOURNAL   Cell Rep 31 (2), 107515 (2020)
   PUBMED   32294428
  REMARK    GeneRIF: AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell
            Synaptic Excitability and Procedural Memory Formation.
REFERENCE   4  (bases 1 to 8151)
  AUTHORS   Tokue,M., Ikami,K., Mizuno,S., Takagi,C., Miyagi,A., Takada,R.,
            Noda,C., Kitadate,Y., Hara,K., Mizuguchi,H., Sato,T., Taketo,M.M.,
            Sugiyama,F., Ogawa,T., Kobayashi,S., Ueno,N., Takahashi,S.,
            Takada,S. and Yoshida,S.
  TITLE     SHISA6 Confers Resistance to Differentiation-Promoting
            Wnt/beta-Catenin Signaling in Mouse Spermatogenic Stem Cells
  JOURNAL   Stem Cell Reports 8 (3), 561-575 (2017)
   PUBMED   28196692
  REMARK    GeneRIF: This study proposes a generic mechanism of stem cell
            regulation in a facultative (or open) niche environment, with which
            different levels of a cell-autonomous inhibitor (SHISA6, in this
            case) generates heterogeneous resistance to widely distributed
            differentiation-promoting extracellular signaling, such as WNTs.
REFERENCE   5  (bases 1 to 8151)
  AUTHORS   Klaassen,R.V., Stroeder,J., Coussen,F., Hafner,A.S., Petersen,J.D.,
            Renancio,C., Schmitz,L.J., Normand,E., Lodder,J.C., Rotaru,D.C.,
            Rao-Ruiz,P., Spijker,S., Mansvelder,H.D., Choquet,D. and Smit,A.B.
  TITLE     Shisa6 traps AMPA receptors at postsynaptic sites and prevents
            their desensitization during synaptic activity
  JOURNAL   Nat Commun 7, 10682 (2016)
   PUBMED   26931375
  REMARK    GeneRIF: Shisa6 prevents synaptically trapped AMPARs from
            depression at high-frequency synaptic transmission.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8151)
  AUTHORS   Farrow,P., Khodosevich,K., Sapir,Y., Schulmann,A., Aslam,M.,
            Stern-Bach,Y., Monyer,H. and von Engelhardt,J.
  TITLE     Auxiliary subunits of the CKAMP family differentially modulate AMPA
            receptor properties
  JOURNAL   Elife 4, e09693 (2015)
   PUBMED   26623514
  REMARK    GeneRIF: This study indicates that AMPAR function is very precisely
            controlled by the cell-type specific expression of the CKAMP family
            members 39, 52 and 59.
            Erratum:[Elife. 2018 Oct 11;7:e42543. doi: 10.7554/eLife.42543..
            PMID: 30306889]
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 8151)
  AUTHORS   Molyneaux,B.J., Goff,L.A., Brettler,A.C., Chen,H.H., Hrvatin,S.,
            Rinn,J.L. and Arlotta,P.
  TITLE     DeCoN: genome-wide analysis of in vivo transcriptional dynamics
            during pyramidal neuron fate selection in neocortex
  JOURNAL   Neuron 85 (2), 275-288 (2015)
   PUBMED   25556833
  REMARK    Erratum:[Neuron. 2016 Jan 6;89(1):235]
REFERENCE   8  (bases 1 to 8151)
  AUTHORS   Schwenk,J., Harmel,N., Brechet,A., Zolles,G., Berkefeld,H.,
            Muller,C.S., Bildl,W., Baehrens,D., Huber,B., Kulik,A., Klocker,N.,
            Schulte,U. and Fakler,B.
  TITLE     High-resolution proteomics unravel architecture and molecular
            diversity of native AMPA receptor complexes
  JOURNAL   Neuron 74 (4), 621-633 (2012)
   PUBMED   22632720
REFERENCE   9  (bases 1 to 8151)
  AUTHORS   Schilling,K. and Oberdick,J.
  TITLE     The treasury of the commons: making use of public gene expression
            resources to better characterize the molecular diversity of
            inhibitory interneurons in the cerebellar cortex
  JOURNAL   Cerebellum 8 (4), 477-489 (2009)
   PUBMED   19554387
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663051.15 and AL663083.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KU707904.1, SRR14777534.36625.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1386              AL663051.15        148364-149749       c
            1387-1547           AL663051.15        125707-125867       c
            1548-1643           AL663083.5         187405-187500       c
            1644-1700           AL663083.5         37182-37238         c
            1701-1853           AL663083.5         32133-32285         c
            1854-8151           AL663083.5         23971-30268         c
FEATURES             Location/Qualifiers
     source          1..8151
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 40.55 cM"
     gene            1..8151
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /note="shisa family member 6"
                     /db_xref="GeneID:380702"
                     /db_xref="MGI:MGI:2685725"
     exon            1..1386
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /inference="alignment:Splign:2.1.0"
     CDS             731..2404
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; protein shisa-6 homolog; shisa homolog 6;
                     cysteine-knot AMPAR-modulating protein 52; cystine-knot
                     AMPAR modulating protein of 52 kDa"
                     /codon_start=1
                     /product="protein shisa-6 isoform 1 precursor"
                     /protein_id="NP_001402693.1"
                     /db_xref="GeneID:380702"
                     /db_xref="MGI:MGI:2685725"
                     /translation="MALRRLLLPPLLLSLLLSLASLHLPPGADAARGRSGNRTLNAGA
                     VGGRRAGGALARGGRELNSTARASGVPEAGSRRGQSAAAAAAAAAAASATVTYETCWG
                     YYDVSGQYDKEFECNNSESGYLYCCGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTP
                     STKVVSPGPENKYDPEKDKTNFTVYITCGVIAFVIVAGVFAKVSYDKAHRPPREMNIH
                     RALADILRQQGPIPIAHCERETISAIDTSPKENTPVRSTSKNHYTPVRTAKQTPGHYG
                     KDAYRSGGPDLHNFISSGFVTLGRGHTKGDRQYNHPILSSATQTPTHEKPRMNNILTS
                     ATEPYDLSFSRSYQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDL
                     AARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPRRGLPDEFGMPYDRILSDE
                     QLLSTERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMTKMHSHPSAS
                     NNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHHTCYTASKTEVTV"
     exon            1387..1547
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1643
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..1700
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /inference="alignment:Splign:2.1.0"
     exon            1701..1853
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /inference="alignment:Splign:2.1.0"
     exon            1854..8151
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8131..8136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /note="hexamer: AATAAA"
     polyA_site      8151
                     /gene="Shisa6"
                     /gene_synonym="ckamp52; Gm879"
                     /note="major polyA site"
ORIGIN      
        1 gagtgcgtgt gtctccctct ctcctatcgc acacgctccg gcactagtgc aggcggttcc
       61 cggctccgct cactcgctcc ggtcgctgcg ctcccgccta gccgccgccg ccgctgcagt
      121 cgcagcccgg catggtgagt gactgaggtg cagccgccgc gcaccccggc tgcccgccgg
      181 accccagcct cagtcggcag caccgtcccc gggctcggcg gcccggtggc ttccccaggg
      241 gttctccacg cgtcctcggg ccactgtccc agtcgggacg cactcctcga gggctgagcg
      301 ctccttctcc gcccggctgc tcgccgctct ccgcaccccg tgaccgctgc cccgtctcgt
      361 cccgcaggac ctgcccggac gggaccacgc cgccgctgcc gccgcctccg ggagccgcgc
      421 ttcggggccg gcctgagccg agtcgcgcgg agccgccgct gccgcgggcg ggggatgggg
      481 ctgcccgcta ggcgcgcgga gcccgcaggg ggagcgcgga gccggcgcgc agcctgagag
      541 ccccgcgcag cccgcgcccc gccgctccgt gcgctcccgc cgccgcccgc gcctcgatgg
      601 cgccatctcc ccgccgctga ccggtccgtc tcgcctttcc agcccgcccg gccgccctcg
      661 gagcccggcc agccgccggg gcagcggcct gcagcccgcg tccgcccgcg ccctcccgcc
      721 cggccccgcc atggcgctgc gccgcctcct gctgccgcct ctgctgctgt cgctgctgct
      781 gtcgctcgcg tccctgcacc tgccgcccgg cgcagacgcc gcccgcggcc gctccgggaa
      841 ccggaccctg aacgcgggag ccgtcggagg tcggcgtgct gggggcgccc tggcccgagg
      901 cggccgcgaa ctaaacagca ccgcccgagc gtccggcgtc ccggaggcgg gcagccggcg
      961 gggacagtcc gcagcagcgg cagcggcggc ggcggcggcg gccagcgcga ctgttactta
     1021 cgagacgtgc tggggctact acgacgtgag cggccagtac gacaaggagt tcgagtgcaa
     1081 caacagcgag agcggctacc tgtactgctg cggcacctgc tactatcgct tctgctgcaa
     1141 gaagcgccac gagaagctgg accagcgcca gtgcaccaac taccaaagcc ccgtatgggt
     1201 gcagacgccc agcaccaagg tagtgtcgcc ggggcccgag aacaagtacg acccggagaa
     1261 ggacaagacc aacttcaccg tctacatcac ttgcggggtg atcgccttcg tcatcgtggc
     1321 gggcgtcttc gccaaggtct cctatgacaa ggcccaccgc cctccgcgag agatgaacat
     1381 ccacagggct ctggctgaca ttctaagaca acagggacca atccccatag cacactgtga
     1441 aagagaaacc atctcggcca tcgatacctc tcccaaagag aacacgccgg tccgatcaac
     1501 ctccaaaaac cactacaccc ctgtgcgcac agccaagcag actccagggc attatgggaa
     1561 ggatgcttac cgaagtggag gaccagatct ccataacttc atctcatctg gatttgtcac
     1621 attaggaaga ggacacacga agggtgatcg tcagtataat catccgatct taagcagcgc
     1681 tacccagacc cctacacatg agaagccacg gatgaataac attctgacgt cggccacgga
     1741 accctatgac ctctccttct cacgctctta ccagaactta gcccacttgc ctccatcata
     1801 tgaatctgca gtgaaaacca atccaagcaa gtactcgtct ctgaagaggc taacggacaa
     1861 ggaagctgat gagtattaca tgagaaggag gcacctgcca gaccttgcag cccgtggtac
     1921 cctccccctc aatgtcatcc agatgtctca acagaagcca cttcctcgag aacggccacg
     1981 caggcccatc agggccatgt cccaggacag ggtcttgtct ccacgtcggg gattgccaga
     2041 tgaattcggc atgccctatg accgcatctt gtctgatgaa cagctgctct ccacagagcg
     2101 cctgcactcc caggacccgt tgctgtcccc agagaggaca gccttcccgg agcagtcgct
     2161 gtcgcgggcc atctcgcata cggacgtctt tgtgtccacg ccagtgctgg accgctaccg
     2221 catgaccaag atgcactccc atcccagtgc ctccaataac tcctatgcca ccctgggcca
     2281 gagccagaca gcagccaagc gccacgcctt tgcctctcgc agacacaaca cggtggagca
     2341 gttacactat atcccaggcc atcacacctg ctacacagcc agcaagactg aagtgaccgt
     2401 gtgaccaaca atgtggccag ggctgcttgg cagagtcagg gcaggacaga gcagagtagg
     2461 gcaggggcga ggagcatccc gccttgctct cctcccctcc ctggatcccc ccattaaagc
     2521 tggaggtggg ctgcctttgt ccagaaagcc atacccccag ggagatggca ccaaatgcct
     2581 ggtccaacaa gcacggacct aggctcttta aagctctttc tctcccagta gacttcccct
     2641 gtagatgaga agtgtagtga ggttcaagtc tttcgaacac ctacaccact ccctcagtcc
     2701 ctgccccgcc ccttcctggg gactcagctg cgggttctgc caaccagtgg accctctcct
     2761 gaaggtaatc ggaagctgcc tgagtttgaa cagctagctg gctagagggt gcagtcagtg
     2821 ggctgaccga ataggctact cggtcttctt cctttatcta caactgcatc gcagataatc
     2881 tcttagtgcc taaaaactgc ctgctcgctc tcagccagag agctgctgtg tccataagca
     2941 caatatgatt ctcttccgcc tgctggaact ctggtctcta ccgagtggcc cttccctcgc
     3001 tgagccctgc agcccaacaa cggggagggg tcccttcctg cagctgcttg gttgcccctg
     3061 cctctgctgt ggggactctg ttctcccagc attcactgtt tctcctcaaa gctctctggg
     3121 gtttaagctc ttgcccccaa gagggggcat tagcccttgc cctccagaga ggagtagcga
     3181 caggttgcca ggactttaga ggtgcctcgg caaccgcctg attgtctcct tacttcctcc
     3241 aggcctcagg tctgaactag gacctcctct caggcctgcc ttcttcacct gagctctgct
     3301 cccaggaggc acctgcggtg ggcagagagc tagggtcggg aggaccactg tgatgcccag
     3361 ggtctcaggg gctcaccatt tccattttct agggctctgc ctgtcccccc atccatgagc
     3421 ctcaggcaga agtttccaga cacagacaga agaagcttag ccctcaaaaa agcaggaacc
     3481 ctctgaggtg gtcatgctag acccttccca gtcctttcca tcatctttgc ccacaccacc
     3541 accccttttc tgtttagaac cctttctttc tccctctgtt ctctcccaga cctatctccc
     3601 accttgctgt ctgcagctcc attacttttc tcagtcagtg gatccaaggg accaagatcc
     3661 attggcagat gcaaataaat aatggtgtcc caggatgttg ctctggggac tgttttgagc
     3721 tttcttcctt gcaggaatgc ttgggcatat ggcagaggca tcttcagctc tgtgaaagac
     3781 cccattgcca gcccagctca gccccatctt tgcctccaac ctgaaggggg acaagatgta
     3841 accagctact gatccaagat cagaaggaag aagacaatga gacaaaacac acacacacac
     3901 acacacacac acacacacac acacacttct gagggccaga gcacctctct gggactgggg
     3961 agaatcagtc cagaatgtct tgtggagaga taaaaccatc acttaccaga ctccagcagc
     4021 aatgccctta catcagattt tatacccctg cccccagttc tgcatggata acccttaaaa
     4081 gtgagatggt gagaagcttg cattcactct ggtcatcttt aatccagcca agtctagaga
     4141 gccacagaga agccagagga ctgctttccc ttcctacttt caagagctgt aggttctcct
     4201 gagccccttc ccagaatccc ccccctccat gagcagctat gttctgcata acccagaagg
     4261 attgaaactg gggtttctaa aggtagtcct tagcctcccc actgaggggg tgtccctggc
     4321 actatgtggc cattctgctt tgctccctgc aaatacaaac cttcttaagg gctggtcccc
     4381 attgggtcta tgagcatttg ttgcagaagg taaggctcac aggaagagag gaactcaatc
     4441 caaatagaga atggctcact ttcagaagca aaggcgtgtc tgacagctgg cccccagccc
     4501 agcaccttgt aactctcctt aacccttagc cagtctcttt gaaggccatg tgctggtgca
     4561 aagggggaag ggcaagactg tggtgggcaa gaatcccctc ccatgtgttt gtacatccca
     4621 tggaaaatct ttcagacacc aagttttgca gcctttgggg agcaagacct tatcccaggc
     4681 tcttccccca gccttggctc tcacaatgtg tctgtctgtc tagcttcttg tctgtctgtc
     4741 tgtctgtctg tctgtctgtc tcaggggctg tttgataagt tgttttccaa actatttctc
     4801 atccctgcct tatcaccatc tggtataaag tacctggcat cagttacatc agaaaattct
     4861 aatgtaatgc ttgcttctcc tgaaggcttt tcttgtgctt catccttgga aggaaaacaa
     4921 taacaaatat aactctacaa actatgttaa tccagtcccc cctccaaact ccagaaaact
     4981 gtgtcttaac tgggacatgg aaaaaacagt aaccaacccc catcttcagt tttgcatgac
     5041 tccatttcaa ttacctgtag acaaccatga tccagaaata tttatatttg tcttaactct
     5101 tttgagagag tccacaatta catagctttt attacagtat attcttataa cttgccctac
     5161 tttattattg tcaatctctt tctgtgccta attttcaaat taaactttat tgtatgtata
     5221 cgaagaaaaa cacaatacct atatagagag tgtgggacta tgtgtggttt cgagcaccca
     5281 atgggattgt tggagcttat ccctcagtga taagggaaaa ccactagatc ccctcaactc
     5341 atctgtcact ccagaaccag ctagctctgt tgctatatga agtcacttga gagtgtctgg
     5401 ggctggaacc ctggtcactg cttctaaccc aagcaggctg gtatcctctg tcacatagga
     5461 ggggcacgga ccccttgtga taaacactca tatcccaagg aaacccaaga cttccttctg
     5521 catgtcttca ctgccctgga cttaggtatg tataggtctc acttacccca agtattcttc
     5581 ctgaagatct cttaccacac ccatccatca ccactccttt cttaccccct ccagtgaact
     5641 cttggctgca tatattcatg agccacaaaa gcttgccaat aattccttaa cctcctaagt
     5701 ggactttgac cgttagaatt ccccagtgtc ttaggcaatg tgtttccctt gagaaggtcc
     5761 agtccttacc ttactgaaat ctctcccctt ctttatattc ttatttctgt cttaacctcc
     5821 tatgccagtt tcctcttgcc ttcctctcat ttctttcttc aatcatccag cttcctccag
     5881 ccctgattcc ttttacctgg gcctgcttaa atctctagtt ttaagaatta gagttcttgg
     5941 tgtaaactgt gaagactctg gcattctgtg ttcaagtcct ctgtttgctt cattggtttg
     6001 ttatacttcc tcacatggga aatgatgtcc caaggtgtga gatcattggg ctccccacat
     6061 ccctatgatc tctaaaaggg aagggagaga gctgcctgat tagaggtgtc atggccaaaa
     6121 gatcagcttt ggctcctgag actacccgac tcaagaagct cttgactaag actgctacta
     6181 gcccagagtc ttctgctctg gccaaagatt catccccttt gatgcttgta gctcttgctt
     6241 atacttcaac tcttgctctc gtagatatca gagctttccc ttcatcccaa agacttgagg
     6301 accttgtaag tcttcaatta tgaggagctg tcatcccaac atcgctgcca ccaaactcaa
     6361 cccatggcct ttggagagtt cttgactgcc acctgcttca tcattcattc cttccacaga
     6421 tgtctgtgga ctgaacccaa ggtcatagtt tgaaagggct gcctatcact tgaaccctag
     6481 aaggcacctg ctctgagagg agcaggcaca ttggccacat tggccactct gccatcctct
     6541 ctgaatctgg gaggatttcc gaatagtttc aagaggcttg ctatgcttta acaaagtatt
     6601 ttcagggctt aagtgttatt ttttataagc agtgcatttt aatggtaggt taaacatgaa
     6661 agacaagtcc ttctggtccc tctctttgtt tttggaagat ggcatatcaa agagagagag
     6721 aaaaaaaaaa ggaccgaggc tctagaacct tggcttctag ttctggcatt tgtctccatc
     6781 ttgccatgtg actatgggca agtcacattc cagtgcctca gtttcctcac ttataaaatg
     6841 agaggctttg gataaatgag cccccaaagt ttcatccagc tcttatgctc tagggttttc
     6901 agtctccacg ctcccttctc taattcatcc ccatttcaac tgagctgtgc ccatcgtact
     6961 ctgcccgccc tgtggcaaca tcactagact cctcgccaga ttttggatgg aaccaatggg
     7021 tttggcattg tagctgaaag ttaaaacctg accgctcaac gggtcaccaa tcacgtgtct
     7081 caaaagcttc tcatataaac atacataaaa tacctgggtg tctgtcgctg tgaaattctg
     7141 agtttggagt tttcattttt gatgttgtcc ttatagctgg agggaggtaa ctctgctttc
     7201 aatgagggga caggctgaaa gatggcccag aagtctgacc atgacatttg ggcatggaat
     7261 ttgtatttaa ggacaaatgg gaaagttgtt ccatgtctca aaggagcatg cttggcagag
     7321 gttctgtgtg gcaagggatg tcatcatatc ccatgccaca gcatgcatcg caaagaccac
     7381 atctggatgc tgaagctcca ccttgactgg agaagacaag gcatgactac cagagctact
     7441 gggaggcggg tctctacccc atcccagtat cttttcggcc cctcttcatg ttattatcac
     7501 cctccccatg aaggcttgca aagcaccaat ggaaattcca agtctctgtc atcaaaccca
     7561 tcttgtaaat cgcaaacaca ttaaccttcc atcattcaga aaagaaaatg atgctgtgtg
     7621 tttgcttaac aacctccctc atataaggga ggagaagacc ctgctcaaca ctgctgccaa
     7681 ccctccaatg ccactccaaa ggaggactca ttcatttgct tcatagtggc aaatacgtct
     7741 ctatcctgta aactcaacta gatattttgt agtaaggaat tcttgaaatt ctctaataaa
     7801 aggcaattct tactgtaaca tttttagttt ggggacacaa tttcctaatg ggggttaagg
     7861 cacattttta ctcattagct ggatttatgg attctatgtt tattatatgg tagtattatg
     7921 aaaagtacct ttctatctgt acctctgcag tttctccatc actcacaggc ctccattact
     7981 gcttctgtac aaagtcacca ttctcctttc ctgtcaaagc acaccctatg tgtactgtaa
     8041 acagagattg cttcagtaag atttagtctt aaggattttt ttccactttt gtcagtaaca
     8101 gatatttatg gatcaaaaaa agtaaaataa aataaagctg tttcaacata a
//
