LOCUS       NM_175259               1817 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus shisa family member 4 (Shisa4), mRNA.
ACCESSION   NM_175259
VERSION     NM_175259.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1817)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1817)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1817)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   5  (bases 1 to 1817)
  AUTHORS   Furushima,K., Yamamoto,A., Nagano,T., Shibata,M., Miyachi,H.,
            Abe,T., Ohshima,N., Kiyonari,H. and Aizawa,S.
  TITLE     Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings
  JOURNAL   Dev Biol 306 (2), 480-492 (2007)
   PUBMED   17481602
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC016814.14.
            
            On Oct 18, 2022 this sequence version replaced NM_175259.4.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK039457.1, BC044813.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-186               AC016814.14        122200-122385       c
            187-358             AC016814.14        121689-121860       c
            359-492             AC016814.14        120463-120596       c
            493-660             AC016814.14        119508-119675       c
            661-1817            AC016814.14        118151-119307       c
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 58.58 cM"
     gene            1..1817
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /note="shisa family member 4"
                     /db_xref="GeneID:77552"
                     /db_xref="MGI:MGI:1924802"
     exon            1..186
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..707
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /note="transmembrane protein 58; protein shisa-4; shisa
                     homolog 4"
                     /codon_start=1
                     /product="protein shisa-4 precursor"
                     /protein_id="NP_780468.1"
                     /db_xref="CCDS:CCDS15319.1"
                     /db_xref="GeneID:77552"
                     /db_xref="MGI:MGI:1924802"
                     /translation="MPPAGPRGTAPLAAVVLLVLGAPLALASEDCLWYLDRNGSWHPG
                     FDCEFFTFCCGTCYQRYCCRDLTLLITERQQKHCLAFSPKTIAGIASAVILFVAVVAT
                     TICCFLCSCCYLYRRRQQLQSTFEGQEIPMTGIPMQPVYQYPPDPKAGPAPPQPGFMY
                     PPSGPAPQYPLYPAGPPIYNPAAPPPYMPPQPSYPGA"
     exon            187..358
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /inference="alignment:Splign:2.1.0"
     exon            359..492
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /inference="alignment:Splign:2.1.0"
     exon            493..660
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /inference="alignment:Splign:2.1.0"
     exon            661..1817
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1600
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /note="major polyA site"
     regulatory      1753..1758
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
                     /note="hexamer: TATAAA"
     polyA_site      1799
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
     polyA_site      1817
                     /gene="Shisa4"
                     /gene_synonym="9330132O05Rik; mShisa4; Tmem58"
ORIGIN      
        1 agagcctggc cgcgggctgg gcggtgctgc agctcccgcc ggccggcttc gtccagcttt
       61 gtcctgcggc cccttttcca ggccgtcctg gccgcgccca gccccctctc gccatgccgc
      121 ccgcggggcc ccgcgggacc gcgccgctcg cagccgtcgt cctgctggtg cttggggctc
      181 ctctggcgct ggcgagtgag gactgcttgt ggtatctgga ccggaatggc tcctggcatc
      241 cgggatttga ctgcgagttc ttcaccttct gctgcgggac ctgctaccag cggtactgct
      301 gcagggacct gaccttactc atcaccgaga gacagcagaa acactgcctg gccttcagtc
      361 ccaagaccat agcaggcatc gcctctgctg taatcctctt tgttgctgtg gttgccacca
      421 ccatctgctg cttcctctgt tcctgttgtt acctataccg aaggcgccag cagctccaga
      481 gcacgtttga aggccaggag attcctatga caggcatccc aatgcagcca gtataccagt
      541 accccccgga tcccaaagct ggccctgcac ctccacagcc tggtttcatg tacccaccta
      601 gcggccctgc tcctcagtat cccctctacc cagctgggcc cccaatctac aaccctgcag
      661 ctcctccgcc ttatatgcca ccacagccct cttatccagg agcctgaaga gacagctgtg
      721 gctctgctgt cccttccgtg atgtcgtttt ttgggttttt tttttttttg ggagagtccc
      781 cgtcctgtac ctgcatctag ccctgagggt gggcaagggt ctcctagtca tcaggccagc
      841 ccccagtcaa accaagcctt gggccctgct gaggacagag ccccagagaa gtggaacgtg
      901 agctgagctg gaaccaggcc gtggatgagg ggtgggtagg gaggacttgg gattcatgag
      961 ctatttttac tgggagactg ggagtaagat gagagcctag gccacagtct ctgttttcaa
     1021 gtcgtccctc tgtgcccagg accccaatca gaaaggtggg acccctccta tatgcccagt
     1081 ttgggctgag gtggagacaa gtgagggggc tctatcaaca gctggccaca gcccttccct
     1141 ctggctgccc aattggctgg agctcaggcc tcctggatta aagctgtaat gctgtaactc
     1201 atcagtggaa tcactggccc cttctcttaa ccctgcctcc tgttgaaccc ggactgctgc
     1261 ctgctccaca ttccacagca ggggagggca gcaccggtgg gaggagagtg ccaccatcag
     1321 ccccatcctg ggcagaaccc ctgagcatct ctggactgtt ttccaacgct gttgagcaga
     1381 tttgtggcag ctagagagag ggtgctcacg tgcttttcag gaccaggcct ctgagacgtc
     1441 caaggcatta ccagctatat aaagacacct ctccatccaa gaacacttac cttccaatct
     1501 gggtctcttc actgtctgac cttgagcttg cctctgagtg tcttcatgta tagaatgggg
     1561 ataatagctg tcaagaggat gatatataat ggaatcgaaa ctatgagtcc gtccttcctt
     1621 cctgatcaga agaggcccag gacctggagc caacatacag aggtgtggtg taaggtactt
     1681 gccggcttga tcctcacagg atgctaaggt gtcagattct acagggcagt gtcccggtcc
     1741 acggaagcta ggtataaaga ctgtgaaggc tacctagaag aggtgacctg ggagtaacac
     1801 agagctgtct gcccatc
//
