LOCUS       NM_001034115            7596 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus SH3 and multiple ankyrin repeat domains 1 (Shank1),
            mRNA.
ACCESSION   NM_001034115 XM_001473991 XM_001474910 XM_001474925
VERSION     NM_001034115.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7596)
  AUTHORS   Qin,Y., Zhang,X.Y., Liu,Y., Ma,Z., Tao,S., Li,Y., Peng,R., Wang,F.,
            Wang,J., Feng,J., Qiu,Z., Jin,L., Wang,H. and Gong,X.
  TITLE     Downregulation of mGluR1-mediated signaling underlying
            autistic-like core symptoms in Shank1 P1812L-knock-in mice
  JOURNAL   Transl Psychiatry 13 (1), 329 (2023)
   PUBMED   37880287
  REMARK    GeneRIF: Downregulation of mGluR1-mediated signaling underlying
            autistic-like core symptoms in Shank1 P1812L-knock-in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7596)
  AUTHORS   Cattaneo,P., Hayes,M.G.B., Baumgarten,N., Hecker,D., Peruzzo,S.,
            Aslan,G.S., Kunderfranco,P., Larcher,V., Zhang,L., Contu,R.,
            Fonseca,G., Spinozzi,S., Chen,J., Condorelli,G., Dimmeler,S.,
            Schulz,M.H., Heinz,S., Guimaraes-Camboa,N. and Evans,S.M.
  TITLE     DOT1L regulates chamber-specific transcriptional networks during
            cardiogenesis and mediates postnatal cell cycle withdrawal
  JOURNAL   Nat Commun 13 (1), 7444 (2022)
   PUBMED   36460641
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7596)
  AUTHORS   Qin,Y., Du,Y., Chen,L., Liu,Y., Xu,W., Liu,Y., Li,Y., Leng,J.,
            Wang,Y., Zhang,X.Y., Feng,J., Zhang,F., Jin,L., Qiu,Z., Gong,X. and
            Wang,H.
  TITLE     A recurrent SHANK1 mutation implicated in autism spectrum disorder
            causes autistic-like core behaviors in mice via downregulation of
            mGluR1-IP3R1-calcium signaling
  JOURNAL   Mol Psychiatry 27 (7), 2985-2998 (2022)
   PUBMED   35388181
  REMARK    GeneRIF: A recurrent SHANK1 mutation implicated in autism spectrum
            disorder causes autistic-like core behaviors in mice via
            downregulation of mGluR1-IP3R1-calcium signaling.
            Erratum:[Mol Psychiatry. 2022 Sep;27(9):3922. doi:
            10.1038/s41380-022-01605-8. PMID: 35538194]
REFERENCE   5  (bases 1 to 7596)
  AUTHORS   Chen,Q.N., Ding,X.L., Guo,X.X., Zhou,G. and Guan,J.S.
  TITLE     Suv39h1 regulates memory stability by inhibiting the expression of
            Shank1 in hippocampal newborn neurons
  JOURNAL   Eur J Neurosci 55 (6), 1424-1441 (2022)
   PUBMED   35181969
  REMARK    GeneRIF: Suv39h1 regulates memory stability by inhibiting the
            expression of Shank1 in hippocampal newborn neurons.
REFERENCE   6  (bases 1 to 7596)
  AUTHORS   Hung,A.Y., Futai,K., Sala,C., Valtschanoff,J.G., Ryu,J.,
            Woodworth,M.A., Kidd,F.L., Sung,C.C., Miyakawa,T., Bear,M.F.,
            Weinberg,R.J. and Sheng,M.
  TITLE     Smaller dendritic spines, weaker synaptic transmission, but
            enhanced spatial learning in mice lacking Shank1
  JOURNAL   J Neurosci 28 (7), 1697-1708 (2008)
   PUBMED   18272690
  REMARK    GeneRIF: These results affirm the importance of Shank1 for synapse
            structure and function in vivo, and they highlight a differential
            role for Shank1 in specific cognitive processes.
REFERENCE   7  (bases 1 to 7596)
  AUTHORS   Uchino,S., Wada,H., Honda,S., Nakamura,Y., Ondo,Y., Uchiyama,T.,
            Tsutsumi,M., Suzuki,E., Hirasawa,T. and Kohsaka,S.
  TITLE     Direct interaction of post-synaptic density-95/Dlg/ZO-1
            domain-containing synaptic molecule Shank3 with GluR1
            alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor
  JOURNAL   J Neurochem 97 (4), 1203-1214 (2006)
   PUBMED   16606358
REFERENCE   8  (bases 1 to 7596)
  AUTHORS   Francke,F., Richter,D. and Bachner,D.
  TITLE     Immunohistochemical distribution of MIZIP and its co-expression
            with the Melanin-concentrating hormone receptor 1 in the adult
            rodent brain
  JOURNAL   Brain Res Mol Brain Res 139 (1), 31-41 (2005)
   PUBMED   15950311
REFERENCE   9  (bases 1 to 7596)
  AUTHORS   Uemura,T., Mori,H. and Mishina,M.
  TITLE     Direct interaction of GluRdelta2 with Shank scaffold proteins in
            cerebellar Purkinje cells
  JOURNAL   Mol Cell Neurosci 26 (2), 330-341 (2004)
   PUBMED   15207857
REFERENCE   10 (bases 1 to 7596)
  AUTHORS   Thuret,S., Bhatt,L., O'Leary,D.D. and Simon,H.H.
  TITLE     Identification and developmental analysis of genes expressed by
            dopaminergic neurons of the substantia nigra pars compacta
  JOURNAL   Mol Cell Neurosci 25 (3), 394-405 (2004)
   PUBMED   15033168
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC152939.2.
            
            On or before Jan 13, 2010 this sequence version replaced
            XM_001474910.1, XM_001474925.1, XM_001473991.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AC152939.2         68561-68593
            34-331              AC152939.2         70961-71258
            332-535             AC152939.2         71416-71619
            536-607             AC152939.2         72049-72120
            608-716             AC152939.2         74330-74438
            717-868             AC152939.2         74641-74792
            869-1036            AC152939.2         77374-77541
            1037-1153           AC152939.2         77940-78056
            1154-1231           AC152939.2         83622-83699
            1232-1298           AC152939.2         83935-84001
            1299-1629           AC152939.2         84253-84583
            1630-1823           AC152939.2         85330-85523
            1824-1937           AC152939.2         91589-91702
            1938-2013           AC152939.2         91840-91915
            2014-2040           AC152939.2         92330-92356
            2041-2123           AC152939.2         100395-100477
            2124-2248           AC152939.2         100717-100841
            2249-2384           AC152939.2         101342-101477
            2385-2465           AC152939.2         101955-102035
            2466-2489           AC152939.2         102595-102618
            2490-2558           AC152939.2         102803-102871
            2559-2677           AC152939.2         103196-103314
            2678-2774           AC152939.2         109245-109341
            2775-5862           AC152939.2         109854-112941
            5863-7596           AC152939.2         114917-116650
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.83 cM"
     gene            1..7596
                     /gene="Shank1"
                     /note="SH3 and multiple ankyrin repeat domains 1"
                     /db_xref="GeneID:243961"
                     /db_xref="MGI:MGI:3613677"
     exon            1..33
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            34..331
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            332..535
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..607
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            608..716
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            717..868
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1036
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1153
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1231
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1298
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1629
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1823
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1824..1937
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2013
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2040
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2123
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2124..2248
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2384
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2385..2465
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2489
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2558
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2677
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2678..2774
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            2775..5862
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
     exon            5863..7596
                     /gene="Shank1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccgaccgg gactcagcag ccccgccagg cagctgcctg tgatgctgct gtcccccgtc
       61 gccccgtggc cccacgatga cccacagccc cgcgacaagc gaggacgagg aaagacacag
      121 tgccagcgag tgtcccgagg ggggctcaga atcggacagc tccccagacg ggccaggaag
      181 aggcccccag gggactcggg gccgaggcag cggagcacct ggtaacctgg cctctacccg
      241 aggcctccag ggacgctcca tgtctgtccc tgacgacgcc cacttcagca tgatggtttt
      301 caggattggc atccctgact tgcatcagac gaaatgccta cgcttcaacc cagatgccac
      361 catctggaca gccaaacagc aagtactctg tgccctgagc gagagtctac aggacgtgct
      421 gaactatgga ctgttccagc cagccacctc aggccgggat gccaacttct tggaggagga
      481 gaggcttcta agagagtacc ctcagtcctt tgagaaaggg gtaccctacc tggagttccg
      541 ctacaagacc cgagtctaca aacagaccaa cctggatgag aaacagctgg ccaagctgca
      601 cacaaagact gggttgaaga agttcctgga atatgtgcag cttgggacgt ctgacaaggt
      661 ggcaaggctg ctggacaagg ggctggaccc caactaccac gactcagatt caggagagac
      721 acctttgacc ctggcggccc agactgaagg ctcagtagag gtgattcgga cgctgtgcct
      781 gggcggggcg catatagact tcagggcccg ggatggcatg acagcgcttc acaaagctgc
      841 atgtgcccgg cactgcctgg cgctcacggc acttctggac cttgggggct cccccaacta
      901 caaggaccga cgagggctga cccccctgtt ccacacagct atggtggggg gagacccccg
      961 ctgctgcgag ctacttctgt acaacagggc ccagctgggc attgcagatg agaacggctg
     1021 gcaggaaatc catcaggcct gccaacgagg gcactctcag cacctggaac acctgctctt
     1081 ctatggggct gagcctggag cccagaatgc ctcaggaaac acggccctgc acatctgtgc
     1141 tctctacaac aaggagacct gtgccaggat cctcctttat cgtggagcaa acaaggatgt
     1201 gaaaaataac aatggacaga cacccttcca ggtggctgtg attgctggga attttgagct
     1261 gggggaactg attcgtaacc atcgggaaca ggatgtggta cctttccagg agtcccccaa
     1321 gtatgcagcc cggcgtcggg gacccccagg cgcagggctg actgtacccc cagcgctgct
     1381 gcgagctaac agtgacacga gcatggcgct gcctgattgg atggtgtttt cggccccagg
     1441 ggcctcatcc tctgggaccc ctggccctac ctcaggatcc cagggccagt cacagccctc
     1501 ggcccccagc accaaactca gtagtgggac cctcagaagt gccagcagtc cccgaggagc
     1561 ccgggcacgc tccccgtccc gggggagaca tcctgaagac gccaagagac aacctcgagg
     1621 ccggcccagc tccagcggga caccccgaga tgggccggct gggggaactg ggggctcagg
     1681 gggccctggg ggctccctgg gcagcagagg cagacgtagg aagctctatt cagcggtacc
     1741 cggtcgctcc ttcatggcgg tgaagtccta ccaggcgcaa ggcgaggggg agatctctct
     1801 gagtaaaggc gaaaagatca aagtgctcag catcggggaa ggaggcttct gggaaggcca
     1861 ggtcaaaggt cgagttggct ggttcccttc tgactgccta gaagaggtgg caaaccgttc
     1921 ccaggaggga agacaagaaa gccgaagtga caaggcaaag agactcttca ggcattacac
     1981 agtgggctcc tatgacagct tcgatgcccc aagtctgatc gatgggattg actcagggag
     2041 tgattacatc atcaaggaga agacagtctt actgcagaag aaggacagtg aggggttcgg
     2101 gttcgtgctc cggggggcca aggcgcagac ccccatcgag gaattcaccc ccaccccggc
     2161 cttcccggcg ctgcagtacc tcgagtctgt ggacgagggt ggcgtggcat ggcgggctgg
     2221 actacgaatg ggagacttcc tcatcgaggt gaacggacag aatgtagtga aggttggcca
     2281 ccgtcaggtg gtcaacatga tccgacaggg aggcaacaca ctgatggtca aggtggtgat
     2341 ggtgaccaga cacccagaca tggatgaggc tgtccacaag aaagcatccc agcaggctaa
     2401 gcggctcccg cccccagcca tctccctgcg ttccaagtct atgacctcag agctggagga
     2461 aatggtctcc ccctggaaga agaaaattga atacgaacaa cagcctgcag cagtgcccag
     2521 catggagaaa aagcggactg tgtatcagat ggcactcaac aaactggatg agatcttggc
     2581 tgcagctcag cagaccatca gtgcaagtga gagtcctggg cctggcggcc tcgcatccct
     2641 gggcaagcac cgacccaaag gattctttgc cactgagtcg agctttgatc ctcaccaccg
     2701 ctcccagcca agttatgacc ggccttcttt cctgcctccc ggacctggcc ttatgctccg
     2761 gcagaaatct atcggggctg cggaagatga cagaccctac ctagcacccc cagccatgaa
     2821 attcagtcgt agcctgtcag tcccgggttc agaggacata cccccaccac ccactacatc
     2881 cccaccagag ccgccctata gcacacctcc ggccccctcc tcttccggcc gcctcactcc
     2941 ctcgcctcgg ggagggccct ttaaccctgg ttccgggggt ccccttcccg cctcctcacc
     3001 ttcatctttc gatgggccat ctcctcctga cccccgtagt gggggccgag agaagagcct
     3061 atatcacagt ggcgccctac cccctgccca ccaccaccca cctcatcacc accatcatca
     3121 cgccccacct cctcagcccc accatcacca tgcgcatcct ccccacccac cggagatgga
     3181 gacaggaggt tcccccgacg atcccccacc tcgattggct ctgggacccc agcccagcct
     3241 tcgaggctgg cgaggtggag gacccagccc gacctcgggg gccccatcac cttcccacca
     3301 cagtagcagc ggaggcagta gcggtcctgc tcaggctccc gccctgcgct acttccagct
     3361 gcccccgagg gcggccagtg cggctatgta cgtaccagcc cgctccggcc gcggtcgcaa
     3421 aggcccgctg gtcaagcaga ccaaagtgga aggcgagccc caaaagggca gcctccctcc
     3481 cgcgtcctct ccaacatccc cggcgttgcc tcggtccgaa ccacctccgg ccgggccgtc
     3541 ggagaaaaat tccatcccta tccctaccat catcatcaaa gccccatcta ccagtagcag
     3601 cggccgcagt agccagggaa gcagcacaga ggctgagccc cccacccagc ccgacggcgc
     3661 gggcggcgga ggatcctcgc ctagccctgc acctgccacg tcccctgtac cgccgtcccc
     3721 gtcgcccgtg cccacccctg cgtcacccag cggcccggcc accctggatt tcactagcca
     3781 gtttggagca gccctagtgg gcgcggcgcg gagggaggga ggctggcaaa acgaagcccg
     3841 gcggcggtcc acgctattcc tgtccaccga cgcaggagat gaggatggag gcgacagcgg
     3901 gctgggcccg ggggcgcccc cgggtccccg gctgcgccat tccaaatcca ttgatgaagg
     3961 catgttctcc gccgagccgt acctccggct ggagtcgggg ggcagcagcg ggggctacgg
     4021 ggcatacgca gcgggcagcc gagcctacgg gggcagcggg agcagcagcg ccttcaccag
     4081 cttcctcccc ccgcggcccc tggtgcatcc gctgaccggc aaagccttgg atcccgcctc
     4141 tccgctgggg ctggccttgg ccgcccggga gcgggccttg aaggagtcct cggagggcgg
     4201 ggtcacccct cagccgcccc cgagacctcc atcaccacgc tacgacgccc caccgcccac
     4261 ccttcaccac cactcgcccc attcacccca ttcgccacat gcgcgtcatg agccagtgtt
     4321 gcgcctctgg ggagacccgg cgcgccggga gctggggtac cgggcaggcc tagggagtca
     4381 ggagaaggcc cttaccgcta gtccacctgc agctcgccgc tcgctactgc accgtcttcc
     4441 cccgacggct cccggggtcg ggccgctcct gcttcaactg gggccggagc ccccaactcc
     4501 ccatcctggg gtgagcaagg cctggcgcac agcagccccc gaggagccag agcggctgcc
     4561 tctgcatgtg cgattccttg aaaattgcca ggcccggcct cctccagctg gcacgagagg
     4621 gtcctccact gaagatgggc ctggggttcc gcctcccagc cctcgcagag tcttgccaac
     4681 ctctcccact tccccgcgag gcaacgagga gaacggcctt ccgctactgg tcctgccacc
     4741 gccagcccct tcggtggatg tggacgacgg cgagttcttg tttgcggagc cgctgcctcc
     4801 acccctggag ttttccaata gcttcgaaaa gccagagtcg cctctcacac ccgggcctcc
     4861 ccacccgctg cctgaccctc cctccccagc tacccctcta cccgcagccc cacctccggc
     4921 tgtggccgcc gcccctccca ccttggactc cacagcatcc agcctgacct cttatgacag
     4981 cgaagtggcc acgttgaccc agggggctcc cgcggctcct ggggaccctc ctgctccagg
     5041 ccctccggcc ccggcagctc cagctcctcc agcaccgcag ccaggccccg accctccacc
     5101 tggcacagat tctggaattg aggaggtgga cagtcggagc agcagcgatc acccgctgga
     5161 gaccatcagc agtgcatcca cactcagcag cttgtccgcc gaaggaggag gcaacacagg
     5221 gggcgtggct gggggcgggg ccggggtggc cagcgggacg gagctcctgg acacctacgt
     5281 tgcctacctg gatggccagg ccttcggggg cagtgggact cctggcccac catatccccc
     5341 tcagctcatg actccttcta agctccgggg cagggcgctt gggactagtg gaaatttgag
     5401 acctggtccc agtgggggac ttcgagatcc tgtcaccccc accagcccca ccgtctctgt
     5461 gacaggagct ggaacagatg ggctactggc cttgagtgct tgttctggac cctcaacggc
     5521 aggtgtggca gggggtcccg tggcggttga gccagaagtc ccgcctgtac ctttgcccac
     5581 tgcctcatcc ctgcctcgga agctactacc atgggaggag ggtccgggac caccaccacc
     5641 acccctgcca gggcccctgt cccagcctca ggcctctgcc ttggccacgg tcaaagccag
     5701 catcatcagc gaactcagct ccaagctcca gcagtttggt ggggcctcta ccgcgggagg
     5761 agctctgcct tgggctcggg gaggcagcgg gggcagcaca gacagccacc acggaggagc
     5821 cagttacatc ccagagagga cctcctccct gcagcggcag aggctctccg aagactccca
     5881 gacctctctc ctctccaaac ccagcagcag catctttcag aactggccta aaccccctct
     5941 gccaccactc cccaccggat ctggggtctc ctcttcaaca gctgcagccc caggagctac
     6001 atccccttca gcctcatctg cctcagcttc caccagacac ctgcagggtg tggaatttga
     6061 gatgcggcct ccgctgctcc gccgggcacc cagcccctcg ctgctgcctg cctcggatca
     6121 caaggtcagc ccagcgccca ggccctcttc tttgcccatc ctgccttcag gacccctcta
     6181 cccgggcctc ttcgacatcc gtagctctcc gaccggaggg gcaggaggct cggctgaccc
     6241 cttcgctccc gtctttgtgc caccacaccc cgggatatct gggggtcttg gaggagcctt
     6301 gtctggggcc tctcgctccc tatcacccac ccgcctgctc tcgctgcccc cggacaagcc
     6361 gttcggcgcc aagcctctag ggttctggac caagtttgac gtcgctgatt ggctggagtg
     6421 gctgggctta tcagagcatc gagcccagtt cctggaccac gagattgatg gctcccatct
     6481 gcccgccttg accaaggagg actatgtgga cctgggcgtg accagggtgg gccaccgtat
     6541 gaacattgac cgggctctca aatttttcct ggagaggtga tggctggcct ggacggacca
     6601 gcccgtccat aggacccttg agcctgctga cctcttgacc tctgacccct ctgaccatca
     6661 ttctctcccc tctcccctca gggggccagg gactctgcta aaactgtgcc tggccccatc
     6721 tccccaggcc tgactgaggt ccccaggtgg acccgatgcg ggccagacaa tggcacctcg
     6781 caagaggtgg gcagctgaca caagactgca agtggagtag agggggggat tagacaaaaa
     6841 tgacaaaggg gtactgaaga aggagggaaa ggccgactgg gggtgggggg acagacagag
     6901 ccatagaggg tcagcccaga gcctgacctg atggggtcct gggaaggtgt gccctccgat
     6961 tccatcattc gcgcccctca aataaccctt ttcacctctc caggcccctc agtcttccct
     7021 ctctccgtgg cacactcagc tgcccagccc ccggcctctt gcacgcctgt tccccttcct
     7081 ggctgcagtt tttgcacaag cttgccccct ggctgtcttg cacacctctg gcctgctgag
     7141 gccctctccg ctccccaaca cgctgcattc tttttttttt tttcttttct ttcttttttt
     7201 tttttttttt ttttttttcc tcaagcgcca ccgccttcgc tagcttgctc tctgcatact
     7261 tgcttctggg ggagaggggt tactgcaccc tttctttctc tagccaccct ggtcccatgc
     7321 tgcagacaca catgggactt tccttccctc tcctgctccc agacccaggc atactcccat
     7381 agcccctggc cacccgtgct ctctgctctc tctgtacatg ctctgaacac actcacctcc
     7441 gctctcacgt ccagggccac tttcctgtct tgccacccct aagcccttac tctccctctc
     7501 atggtggcac tcctgtgccc ggccttctct attttctctg acacttagca cacccctcac
     7561 actcatggcc ctgaactctt tccaaatgtt taaccc
//
