LOCUS       NM_013709               1747 bp    mRNA    linear   ROD 28-AUG-2024
DEFINITION  Mus musculus Sh3 domain YSC-like 1 (Sh3yl1), transcript variant 1,
            mRNA.
ACCESSION   NM_013709 XM_974495 XM_974537 XM_974578
VERSION     NM_013709.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Lee,S.R., Lee,H.E., Yoo,J.Y., An,E.J., Song,S.J., Han,K.H.,
            Cha,D.R. and Bae,Y.S.
  TITLE     Nox4-SH3YL1 complex is involved in diabetic nephropathy
  JOURNAL   iScience 27 (2), 108868 (2024)
   PUBMED   38318360
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  AUTHORS   Choi,G.S., Min,H.S., Cha,J.J., Lee,J.E., Ghee,J.Y., Yoo,J.A.,
            Kim,K.T., Kang,Y.S., Han,S.Y., Bae,Y.S., Lee,S.R., Yoo,J.Y.,
            Moon,S.H., Lee,S.J. and Cha,D.R.
  TITLE     SH3YL1 protein as a novel biomarker for diabetic nephropathy in
            type 2 diabetes mellitus
  JOURNAL   Nutr Metab Cardiovasc Dis 31 (2), 498-505 (2021)
   PUBMED   33223406
  REMARK    GeneRIF: SH3YL1 protein as a novel biomarker for diabetic
            nephropathy in type 2 diabetes mellitus.
REFERENCE   3  (bases 1 to 1747)
  AUTHORS   Yoo,J.Y., Cha,D.R., Kim,B., An,E.J., Lee,S.R., Cha,J.J., Kang,Y.S.,
            Ghee,J.Y., Han,J.Y. and Bae,Y.S.
  TITLE     LPS-Induced Acute Kidney Injury Is Mediated by Nox4-SH3YL1
  JOURNAL   Cell Rep 33 (3), 108245 (2020)
   PUBMED   33086058
  REMARK    GeneRIF: LPS-Induced Acute Kidney Injury Is Mediated by
            Nox4-SH3YL1.
REFERENCE   4  (bases 1 to 1747)
  AUTHORS   Hasegawa,J., Tokuda,E., Tenno,T., Tsujita,K., Sawai,H., Hiroaki,H.,
            Takenawa,T. and Itoh,T.
  TITLE     SH3YL1 regulates dorsal ruffle formation by a novel
            phosphoinositide-binding domain
  JOURNAL   J Cell Biol 193 (5), 901-916 (2011)
   PUBMED   21624956
REFERENCE   5  (bases 1 to 1747)
  AUTHORS   Shimomura,Y., Aoki,N., Ito,K. and Ito,M.
  TITLE     Gene expression of Sh3d19, a novel adaptor protein with five Src
            homology 3 domains, in anagen mouse hair follicles
  JOURNAL   J Dermatol Sci 31 (1), 43-51 (2003)
   PUBMED   12615363
REFERENCE   6  (bases 1 to 1747)
  AUTHORS   Aoki,N., Ito,K. and Ito,M.
  TITLE     A novel mouse gene, Sh3yl1, is expressed in the anagen hair
            follicle
  JOURNAL   J Invest Dermatol 114 (5), 1050-1056 (2000)
   PUBMED   10771491
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK141199.1 and AV375458.1.
            
            On Jan 23, 2014 this sequence version replaced NM_013709.4.
            
            Transcript Variant: This variant (1) encodes the longer protein
            (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141199.1, BC110043.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1736              AK141199.1         2-1737
            1737-1747           AV375458.1         217-227
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 13.01 cM"
     gene            1..1747
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /note="Sh3 domain YSC-like 1"
                     /db_xref="GeneID:24057"
                     /db_xref="MGI:MGI:1346118"
     exon            1..559
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            560..670
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            671..784
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            785..849
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            850..962
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1091
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1254
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1333
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1390
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1747
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1577..1582
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /note="hexamer: ATTAAA"
     polyA_site      1605
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /note="major polyA site"
     regulatory      1721..1726
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
                     /note="hexamer: AATAAA"
     polyA_site      1744
                     /gene="Sh3yl1"
                     /gene_synonym="Ray; YSC84"
ORIGIN      
        1 agagggcggg gcttaggcgt tcgggttggc agcccgggct agcgttcact ctgagctctg
       61 cccaggtcgc acgtctaagg agtgagggcg gggtgaacgc ggggcgaccc ccagagcagc
      121 ttgggtggca cggtgttgag cagggaggat taggatgtgc cagggcagcc aatgaactca
      181 aggatagcgg cttgcagagc ctcctagggt ggctcctccg atcggagcta cccgcccttc
      241 caagctaagt tacccctttg gaccaccgac cccaggccgg gccacggtac ttagcagtgg
      301 gtttccccga ttaagaagag ggggtgattt acaaggcttc aaaggaatga ggcgggtgga
      361 cgcagatgag ctacgttctg agcaagggta taggaccagt gatcgctttg gcaaaaacag
      421 ggcatacacc tattccctta cctgggtcag gtgtgcgccc gctgggcggg tcccgtcagg
      481 gaggcggacc aaggagaacg ctttcctctt cctggactgg agtgaggagc tcgggtaccg
      541 agaggagcgg caggcaccat gaataacccg ataccttcta atctgaaatc agaagcaaag
      601 aaggctgcca aaatattaag agaattcaca gaaataactt ctagaaatgg acctgataag
      661 atcattcctg cccacgtgat tgcaaaagct aaaggtcttg cagttttgtc tgtgattaaa
      721 gccgggtttc tggtcacagc caggggaggc agtgggattg tcctggcgcg tcttccggat
      781 ggaaaatggt ctgcaccttc agccattggg atagctgggc ttggtggagg atttgaaata
      841 ggaatagagg tatccgattt ggtgataatt ctgaattatg acagagcagt agaagccttt
      901 gcaaagggtg gaaacctgac ccttggaggg aattttactg tcgcagttgg gcccctaggc
      961 aggaacctgg aaggcaacgt gtccctgagg agctccgcag ccgtcttcac atactgcaag
     1021 tccaggggcc tctttgctgg tatctccctg gaaggaagct gtctgattga gaggaaagaa
     1081 accaatcgga aattttactg tcaggacatt cgagcttacg acattttatt tggagatgtt
     1141 ccgcagcctg ctcaagcaga agatctttat gaaattctta attccttcac tgagaaatat
     1201 gaaactgaag ggcagcgcat caatttgaag aaagtagccc gggagcagag gaaggccaaa
     1261 gaattacctc caaaaccatc ttcaaggccc cagccagccc acccacctgt acagctgaat
     1321 gctggctccc agggtaatag aaatgaatat aagctatatc ctgagctttc tagctatcat
     1381 gagaaaactg gcaatttgaa tcaaccaata gaagtgacag cattatactc tttcgaagga
     1441 caacagccag gagacttgaa ttttcaagca ggagacagaa tcatagttat atcaaagacc
     1501 gactcaaatt ttgattggtg ggaaggaaaa cttcgaggtc aaactggaat tttcccagcc
     1561 aactatgtaa ctatgaatta aagttcatgc tattttgtta cttgataatt acacaaaaat
     1621 atttctacac agacaggatt cactgtttac tgcaaacgtc aagcacaccc ttgctctgca
     1681 aatgttttta tccaggtgta aaatattttc tctgcatata aataaatggt taagttaaca
     1741 tgcagct
//
