LOCUS       NM_173778               3067 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus SH2 domain containing 7 (Sh2d7), mRNA.
ACCESSION   NM_173778 XM_006511157
VERSION     NM_173778.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3067)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3067)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT010507.11.
            
            On or before Mar 11, 2019 this sequence version replaced
            XM_006511157.1, NM_173778.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.1053983.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-199               CT010507.11        68664-68862         c
            200-289             CT010507.11        67287-67376         c
            290-455             CT010507.11        63856-64021         c
            456-662             CT010507.11        63401-63607         c
            663-1349            CT010507.11        61485-62171         c
            1350-3067           CT010507.11        57966-59683         c
FEATURES             Location/Qualifiers
     source          1..3067
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 29.7 cM"
     gene            1..3067
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /note="SH2 domain containing 7"
                     /db_xref="GeneID:244885"
                     /db_xref="MGI:MGI:2441692"
     exon            1..199
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..1400
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /codon_start=1
                     /product="SH2 domain-containing protein 7"
                     /protein_id="NP_776139.2"
                     /db_xref="CCDS:CCDS23190.2"
                     /db_xref="GeneID:244885"
                     /db_xref="MGI:MGI:2441692"
                     /translation="MEGGPEQLHLGKALEEAGGGRALAEIQELALKWFMETQAPSILQ
                     NGVLPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRAVGYILSYRGSDRCRHFVINQL
                     RNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAINTGLQH
                     TNLSLKIPATEFPSMLPDKATSPRLPAKPQVSFLHKKALDMSSRSVSDEVSAEVPTRV
                     PPIPRRSPSLLDESPAGPSDVIYTDLRKINRAQLGLGTEVWGTLRPASAGSLACSPGR
                     EPSGKLSDEDQNKPNSLGPAPSGMKPDQGSTMPYTSLGFSLPPSSETLGSQATTWRQG
                     FLKLSHEAQSSSEASSTDTYHLVETPGLQQEARDRPDQRGSPYEQIPTCWHGTAKLSY
                     PGVSPTYSQQSGPMDYGYEKISGTSKLPEPGNTYEQIPAAKNKDTGRVHKPDKFRRLF
                     FTDKKHKF"
     exon            200..289
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            290..455
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            456..662
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            663..1349
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..3067
                     /gene="Sh2d7"
                     /gene_synonym="4933412E14Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acatatcatc agtgctcacc aggatggagg gcggcccaga gcagctccat ctgggcaagg
       61 cactggagga ggcagggggt gggcgggcct tggctgaaat ccaagagctg gctctgaagt
      121 ggttcatgga gacacaggcc ccctctatcc tacagaatgg agttctgccc ccctggtttc
      181 atggattcat cactcgcaag caaacagagc agctactcag ggacaaagcc ctcggttcct
      241 tcctcatccg cctcagtgac cgggctgtcg gctacatctt gtcttatagg ggcagtgatc
      301 gctgccgcca ttttgtcatc aaccagctgc gaaatcgacg ttaccttgtc tcaggagaca
      361 ccctcagcca cagcaccctg gatgagctcc tacgccatta ccaggaggtg cagctcgagc
      421 cttttgggga gacccttgct gctgcttgcc cacggctaga ggaaaatgat ctgtatgatg
      481 ccatcaacac gggcctccag cacactaatc taagcctgaa aattccagcc acagaatttc
      541 ccagcatgct ccctgacaag gccaccagtc cccgccttcc tgcaaagccc caggtctctt
      601 tcctgcacaa gaaagcccta gacatgagtt cccggtctgt ctcggatgaa gtgagtgcag
      661 aggtacccac tagagtgccc cccatccccc ggaggagtcc ctctcttctg gatgagtctc
      721 ctgcaggccc cagtgacgtc atctacacag acctaaggaa gataaaccgg gcacagctag
      781 gcctgggcac agaggtgtgg ggcacgctca ggccagcttc tgctggcagc ttggcttgtt
      841 ccccaggcag ggagccctca gggaaactct cagatgaaga tcaaaacaag cccaatagcc
      901 taggacctgc cccatctggg atgaagccag accaaggctc tacaatgcct tatacttcct
      961 tgggattttc cctgcccccc agttctgaga ccctgggatc ccaggctact acttggaggc
     1021 aggggtttct gaagctgagc cacgaggctc agtcctcctc tgaagcaagc tctacagata
     1081 cctaccacct tgttgagaca ccaggcctac aacaagaggc cagggacaga ccagaccaaa
     1141 gaggcagtcc ttacgagcag attccaacct gctggcatgg cactgccaag ctctcatacc
     1201 ctggagttag tcccacatac agccaacaat cagggccgat ggactatggc tatgagaaga
     1261 tttcagggac ctcgaagctc ccagagccag gaaacaccta tgagcagatc ccagccgcca
     1321 agaacaagga cactggacga gtgcacaagc ctgacaagtt ccggaggctc ttcttcacag
     1381 acaagaagca caaattctga ggaaaggcct ggcactcaga gggtttggtg gtatccacac
     1441 tgcaccaggg attactggat actcttagct cacttgaagg tgtgacccaa ccatctgcta
     1501 tggaacgtgg ctccaggatg cagcctaggt acctatctgg gaaggcacag gagagacttt
     1561 gtagcagcct gcaaccccag gatgtctctt caatgctgtc catccacaca atgaaggaat
     1621 aaggctggca agagggggga ctaactaaag gaagaggtgg atgaacgtga agaggcctgg
     1681 gctgactgac caagctcgcc tcatacctcg atacttaaca agtatgtggc aggtcccttg
     1741 tcaagacaga cattttccag attgtctaaa tgacatcatg ctattacttc tgagaacaaa
     1801 accagttccc ttcctcatgg ccttgccagg agatggggga gacgccagga gccacatcct
     1861 ccacacctgc ctcagaagga ttaaacccag gagcttggga tacagcagcc aaggtccaac
     1921 ttcagaagcc atggtcctaa ctcagcagca ggctgggctc ctaagaatcg cccccagccc
     1981 ttcctgcccc acttctccat ctttatccta gcatcagtat gcaaactcct agtttgtgct
     2041 gcagacacct atttgaagac atagctagtg agggtctgca cagagatccc ctcaataagt
     2101 ggggcttaag ctctgaatgt acagctgagc agcatctgga gccaatcagg ggatatctga
     2161 tgccatgctt atgtgagcag gtcaccccta cctgccctct gtctccagcc agtcctgacc
     2221 tttggagcag ctcagattcc tcccatgcaa cccaccatga acctggcgat gtcacttcta
     2281 gagacttttg ggagtcacca gttttggagt aggacattct tgctccagct gttcccttgg
     2341 ccaagctggc tcttccaggg attgttctta tttggtactg ttccccttca tccatgtgtc
     2401 cccaaatcca ttgggcaagc aactggcctg ctatcttctc tctaccctgt ctctacaagc
     2461 aggaggcagg aaccaagacc acagtcccct ctccaactgg ctccacccag gccctgggca
     2521 gaactagctc agtgcacact gtggggaaat ccactccttg gtggatattt ggttaacaca
     2581 ctttccctct gaactctaca agtccccatc tacttggggt ggtggaaagt ttaagactag
     2641 caggaaaacc ctgagccgag caatggtgag ctctctgtag gtagacaaat ctatttttag
     2701 ggaaatggaa acaatcctca cccaacatcg tgaagccaac gttagcatct gacacggagg
     2761 gcaatgcttc actggggtgt cagggacggc ctgaaagagt gccaccgaac actcctaatg
     2821 ctgacagaca cggagagtga gtgcagcaca caaaaagtgt tttatttcta ggagttcaca
     2881 aatctgaggt cagcacacat aagtgatacc atgtcatcag ggaggtgggg tggggtagtg
     2941 ttcaagacac aggggcagag ccctttggac cgaaccttat acagcttcac attgggaaag
     3001 tacgggggcg gaggtggtac agcccagcct tggctttggt aaaagattgc atagcttgtt
     3061 aaagccc
//
