LOCUS       NM_172718               5171 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus small G protein signaling modulator 1 (Sgsm1),
            transcript variant 1, mRNA.
ACCESSION   NM_172718
VERSION     NM_172718.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5171)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5171)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5171)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 5171)
  AUTHORS   Zhang,Z., Wang,S., Shen,T., Chen,J. and Ding,J.
  TITLE     Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the
            molecular basis for the binding specificity of Rab9A with RUTBC2
  JOURNAL   Structure 22 (10), 1408-1420 (2014)
   PUBMED   25220469
  REMARK    GeneRIF: Crystal structure of the Rab9A-RUTBC2 Rab-binding domain
            complex reveals that RUTBC2 Rab-binding doamin adopts a PH domain
            fold and mainly uses beta1 and eta1 insertion to bind Rab9A.
REFERENCE   5  (bases 1 to 5171)
  AUTHORS   Luo,Y., Sarabi,S.A., Backman,C., Shan,L., Hoffer,B. and Federoff,H.
  TITLE     Expression pattern of NuIP gene in adult mouse brain
  JOURNAL   Brain Res 1302, 42-53 (2009)
   PUBMED   19765553
  REMARK    GeneRIF: Overall, the expression pattern of NuIP in adult mouse
            brain suggests that it may be involved in motor activity control in
            basal ganglia as well as higher central nervous system (CNS)
            functions such as cognition and memory in cortex and hippocampus.
REFERENCE   6  (bases 1 to 5171)
  AUTHORS   Luo,Y., Xing,F., Guiliano,R. and Federoff,H.J.
  TITLE     Identification of a novel nurr1-interacting protein
  JOURNAL   J Neurosci 28 (37), 9277-9286 (2008)
   PUBMED   18784308
REFERENCE   7  (bases 1 to 5171)
  AUTHORS   Yang,H., Sasaki,T., Minoshima,S. and Shimizu,N.
  TITLE     Identification of three novel proteins (SGSM1, 2, 3) which modulate
            small G protein (RAP and RAB)-mediated signaling pathway
  JOURNAL   Genomics 90 (2), 249-260 (2007)
   PUBMED   17509819
REFERENCE   8  (bases 1 to 5171)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   9  (bases 1 to 5171)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130548.3, AK053555.1, AK044716.1, AK167632.1 and BP761545.1.
            
            On Jul 2, 2009 this sequence version replaced NM_172718.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053555.1, BC138049.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                AC130548.3         52146-52212
            68-503              AK053555.1         2-437
            504-1742            AK044716.1         458-1696
            1743-3596           AK053555.1         1677-3530
            3597-3597           AK167632.1         2748-2748
            3598-5152           AK053555.1         3532-5086
            5153-5171           BP761545.1         17-35               c
FEATURES             Location/Qualifiers
     source          1..5171
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 55.45 cM"
     gene            1..5171
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /note="small G protein signaling modulator 1"
                     /db_xref="GeneID:52850"
                     /db_xref="MGI:MGI:107320"
     exon            1..113
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..3376
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /note="isoform a is encoded by transcript variant 1; RUN
                     and TBC1 domain containing 2; nurr1-interacting protein;
                     RUN and TBC1 domain-containing protein 2"
                     /codon_start=1
                     /product="small G protein signaling modulator 1 isoform a"
                     /protein_id="NP_766306.2"
                     /db_xref="CCDS:CCDS39218.1"
                     /db_xref="GeneID:52850"
                     /db_xref="MGI:MGI:107320"
                     /translation="MASVPAEAETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIIS
                     FCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKGFPPAEELSRKVQELEQLIESAR
                     NQIQGLQENVRKLPKLPNLSPLAIKHLWIRTALFERVLDKIVHYLVENSSKYYEKEAL
                     LMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHLRQDSPTK
                     RPALCIQKRHSSGSMDDRPSISARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAVPG
                     YLSLHQTADVMTLKWTPNQLMNGSVGDLDYEKSVYWDYAVTIRLEEIVYLHCHQQVDS
                     GGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPK
                     LRKRSPQGSSESTSSDKEDDEATDYVFRIIYPGTQSEFVPQDLMDVSMNNLPPLWQPS
                     PRKSSCSSCSQSGSADGGSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLST
                     VRTHLSALVNHMIVSPDLPCDAGQGLTASIWEKYIQDSTTYPEQELLRLIYYGGVQPE
                     IRRAVWPFLLGHYQFGMTEMERKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAA
                     LAKCSSGASLDSHLHRMLHRDSTISNESSQSCSSGRQNLRLQSDSSSSTQVFESVDEV
                     EQTEAEGRSEEKHPKIPNGNPANGTCSPDSGHPSSHNFSSGLSEHSEPSLSTEDSVLD
                     AQRSLPAVFRPGDSSVEDGQSSEATTSRDEAPREELAVQDSLESDLLANESLEEFMSI
                     PGSLDVALPEKDGAVMDGWPGEADKPSRADSEDNLSEEPEMESLFPALASLAVTSSAN
                     NEASPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYI
                     WQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMR
                     SLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSS
                     AHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNAKQILQLARDLVHKVQI
                     LIENK"
     exon            114..157
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            158..233
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            234..396
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            397..549
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            550..617
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            618..763
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            764..895
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1020
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1088
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1252
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1385
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1524
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1589
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1735
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1864
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..2047
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2116
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2117..2704
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2829
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2830..2912
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2913..3022
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3023..3119
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3120..3287
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..5161
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5138..5143
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /note="hexamer: AATATA"
     polyA_site      5161
                     /gene="Sgsm1"
                     /gene_synonym="2410098H20Rik; D5Bwg1524e; E130107M15;
                     NuIP; Rutbc2"
                     /note="major polyA site"
ORIGIN      
        1 gtcattcatc ccctgccggt cccgccccct cgcggctgca gcagggcgcg gagcggggac
       61 gcgtccggga accgggcacc gaccagcttg agccatggct tcggtccctg cggaggccga
      121 gacccgccag aggctgctgc gcactgtgaa gaaggaggtg aagcagatca tggaagaagc
      181 cgttaccaga aagttcgtcc acgaggacag cagccacatc atctccttct gtgcggccgt
      241 ggaggcctgc gtgctgcacg ggctgcggcg gagggcggcc ggcttcctgc gaagcaacaa
      301 gatcgcggcg ctcttcatga aggtgggcaa aggcttccct ccggccgagg agctgagccg
      361 caaggtccag gaactggagc aactcattga gagcgcgcga aaccagatcc agggcctgca
      421 agagaacgtg cggaagctgc cgaagctgcc taacctgtcc ccgctggcca tcaagcacct
      481 gtggatccgc accgccctgt tcgagagggt cctggacaaa atcgtccact acctggtgga
      541 aaacagcagt aaatactacg agaaggaggc actcttgatg gacccggtgg acggacccat
      601 cctggcctct ttgttggtgg ggccatgtgc cctggagtat accaagatga agactgcaga
      661 tcacttctgg actgacccct cagccgacga gctggtccag agacaccgga tccacagctc
      721 acatctgaga caggactcgc ccaccaagcg gccagcgctc tgtatccaga agaggcattc
      781 cagtggcagc atggacgacc ggccatctat ctctgcccgg gactatgtag aatctctgca
      841 ccagaactcc agggccaccc tgctctatgg aaagaacaat gttctggttc agccaaggga
      901 tgacatggag gccgtgccag ggtacctgtc tctgcaccag acagcggatg tcatgacctt
      961 gaagtggaca cccaatcagc tgatgaacgg gtctgtgggg gatctggact acgagaagag
     1021 tgtctactgg gactacgctg tgaccatccg cttagaggag atagtttacc tgcactgcca
     1081 tcaacaagtg gacagcggcg ggactgtcgt gctggtgagc caggatggaa tccagaggcc
     1141 acccttccgc ttccccaagg gcgggcacct gctacagttc ctctcctgtc tggagaatgg
     1201 gctgcttccg cacgggcagc tggacccgcc gctttggtca cagcgaggaa aggggaaggt
     1261 atttcctaag ttgcgcaagc gcagcccaca ggggtcctcc gagtccacgt cttcagacaa
     1321 ggaggacgac gaagccacgg attacgtgtt ccgcatcatc taccctggca cgcagtctga
     1381 attcgtgccc caggacctaa tggatgtctc tatgaacaac cttccacccc tatggcaacc
     1441 cagtcctcgg aagtcctcct gctcttcctg ttcacaaagc ggctcagctg acggcggctc
     1501 aaccaatggc tgtaaccatg agagggcccc actgaaactg ctgtgtgata acatgaagta
     1561 ccagatcctc tccagagcct tctatggatg gctcgcctac tgcagacacc tgtccaccgt
     1621 gaggacccac ctgtcagccc tggtcaatca catgatcgtg tctccagacc tgccctgtga
     1681 cgctgggcaa gggttgacag ccagcatctg ggaaaaatac atccaggaca gcacgaccta
     1741 cccggagcag gagctgctgc gtctcatcta ctatggaggt gtccagcctg agatccgcag
     1801 ggcagtgtgg cccttcctcc tcggccacta ccagtttggg atgacagaga tggagaggaa
     1861 agaggtagac gaacagatcc atgcctgcta cgcacaaacc atgtcggagt ggctgggctg
     1921 tgaagctatc gtgagacaga gggagcggga gtcccacgcg gctgccctgg ccaagtgctc
     1981 ttcaggagcc agcctggaca gccaccttca ccggatgctg caccgggact ccaccatcag
     2041 caatgagtca tcccagagct gcagctcagg ccgccagaac ctccgactgc agagcgactc
     2101 cagcagcagc acacaggtat ttgagtctgt ggatgaggtg gagcagacag aggcagaagg
     2161 caggtcagaa gaaaaacatc ccaaaatccc caatgggaac ccagccaacg gcacttgctc
     2221 cccagactcc ggacaccctt cctcccacaa cttctcctct ggtctctccg agcactctga
     2281 gcccagtctt agcactgaag acagcgtctt ggatgcccaa cgcagccttc cagctgtgtt
     2341 tcggcctggg gacagcagcg tggaagatgg gcagagcagc gaagccacca catcccggga
     2401 cgaggcccct cgggaggagc tggccgtgca agatagcctt gagagtgacc tccttgccaa
     2461 cgagagcttg gaggagttca tgtctatccc tggcagcctg gacgtggccc tacctgagaa
     2521 ggatggcgcg gtgatggacg gctggcccgg tgaggcggac aagcccagtc gggctgacag
     2581 tgaggacaac ctctcagaag agcctgagat ggagagcctg ttccctgccc tggcttctct
     2641 ggctgtgacc tcctctgcca ataacgaggc atcccctgtg tcctccagtg gagtcaccta
     2701 ttctccagaa ctactggacc tgtacaccgt gaacctgcac cgcattgaga aagatgtgca
     2761 gaggtgtgac cgcagctact ggtacttcac agcagccaac ctggagaagc tgaggaacat
     2821 catgtgcagc tatatctggc agcacatcga gatcggctac gtccagggca tgtgtgacct
     2881 cctggccccg ttgctggtca tcctggatga tgaggccctg gccttcagtt gcttcacgga
     2941 gctgatgaag aggatgaacc aaaacttccc ccatggaggc gccatggata cgcacttcgc
     3001 caacatgagg tctctgatcc agatcctgga ctccgagctc ttcgagctga tgcatcagaa
     3061 cggcgattac acccacttct acttttgcta ccgctggttc ctgctggatt tcaaacgaga
     3121 gctggtctat gatgacgtct tctccgtgtg ggaaactatc tgggctgcta agcacgtgtc
     3181 ctccgcccac tacgtgctgt tcatcgcgct ggcgctggtg gaggtctaca gagacatcat
     3241 cctggagaac aatatggact tcactgacat tatcaagttc ttcaacgaaa tggctgagcg
     3301 gcacaacgcc aagcagattc tgcagctcgc ccgggacctc gtgcataagg tgcagattct
     3361 aattgagaac aagtgaggat ctgctgtcgt ccaccacccc caccccttcc ttcagcccag
     3421 cacaaggtcc tggtgtctgt ggaccagtat ggacttctgt gaagagagcc atgctcttac
     3481 ccttggccac tgggcagagg ggtagagaag aacccatctc ggccttacat tttcctgttt
     3541 gaccaaagat tgcccaagtc tgggatatcc ccctttcttg ggagttgggg ttgtgagtgg
     3601 gtcgaggtag cctctggctc tgttgtcctt cttccttttc tctgttcctt cctcatctgc
     3661 acaggagagg cctgtggggt ttcctctgca cccagcaagg aagggccttt ggtggtgttc
     3721 tagaatgttc ctgccaggct ggctcggaac aggctgtccc cgtagacatt gctcacattc
     3781 aaagtcccag atgttttgag catcacccct gccttcgaac caccaggttt ccccccaccc
     3841 ccaaggtaac cctgatgtcc ttttatggct tgtctgcccc tcagagaacc actggcttgg
     3901 aagaggggct aacagcatgt ctccatgtat ccttctcacc tgaggtctgt tccgtgcccc
     3961 tggcagcagc ttctgactgc ctgagtcctc gatctaatga cctaacttcc tgcgctttcc
     4021 aacttttctc tatccgctgc caggagactc tctttagaaa aggcatcctg taggtgggct
     4081 aggggtcctg gacgtgtttg taggcagaag ccaggagctc ttgatgagag cctaaccctt
     4141 actatctcac cctcagggag acctccctgc catcaccagt gatctgggct cagaagcctg
     4201 cagccttggt ggaagccatg ctcagcaagg ctgggttttc tctaagcact ttgttcactc
     4261 aggacagaag gaaggatgag ccagtgggtt ggccagtgat agggttggtc tgtgttccat
     4321 gatggggagc ttggggccag ggttgggcct gaatatgttc cctctacacc ttcataccaa
     4381 gacctgctga tccacacact gaccctgagt aagctttcat acccgctcac tgtctcttag
     4441 tgaagcagtc cagggtgcag cagaaatgag cacacatagc agaagcttgt ccccaggacc
     4501 tgcagcctct gggggcaatc aagacatggc aagtaggatt ttataaagag gatacgtggc
     4561 ttgaagcagc tgcagagggt accttcagcc ttgagccaca ctcttaaatc agaacctgtg
     4621 tctcccacac agggcaaggt ggacagagag agctctgtag tgtccatgga agactgatgc
     4681 tgcttcagcc cacttgtgcc cagggcagca ggaagggagg cggctgatga ccacagttgc
     4741 ctgtgtagag tcacacctcc cagctaggtc cccctgcttc ccaaggtgtg ggtaagaaag
     4801 gccatcagat aaaagttgat tttgctggtg cagaggttgg tattttagca cagccaggtc
     4861 cggagctcct gatccttatt tatttttgta actgaccagt gtggagtata gcacaagaat
     4921 tccctctgcc tccctcgtgc ctcccgagcg cgtgcttgtg gttctgagtg cctcctattt
     4981 attccattta ccagctgacg tctgtgtgcg gtgtttcttg gtgtcctgga gttgggcatg
     5041 ggcgggaggg gggtattcct cctgcccaag gcgttctctt tttcacgttg cccaagtgtc
     5101 ttgtaaatgt tcattgcaaa gatgactatt cagagcaaat atatctgagc agaaaacata
     5161 aaaaaaaaaa a
//
