LOCUS       NM_001195687            3739 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus shugoshin 2B (Sgo2b), mRNA.
ACCESSION   NM_001195687 XM_146372 XM_910971
VERSION     NM_001195687.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3739)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3739)
  AUTHORS   Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J,
            BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta
            A, Hansen G, Hu Y, Huang W, Jaing C, Key BW Jr, Kipp P, Kohlhauff
            B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick
            J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N,
            Zhu Q, Person C and Sands AT.
  TITLE     Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap
            screen to identify potential targets for therapeutic intervention
  JOURNAL   Proc Natl Acad Sci U S A 100 (24), 14109-14114 (2003)
   PUBMED   14610273
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC149051.4.
            
            On or before Sep 24, 2010 this sequence version replaced
            XM_910971.2, XM_146372.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: HM628725.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMN01164136,
                                    SAMN01164137 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-233               AC149051.4         112869-113101       c
            234-359             AC149051.4         104028-104153       c
            360-535             AC149051.4         101935-102110       c
            536-613             AC149051.4         100955-101032       c
            614-699             AC149051.4         99299-99384         c
            700-941             AC149051.4         92186-92427         c
            942-3566            AC149051.4         87397-90021         c
            3567-3739           AC149051.4         85625-85797         c
FEATURES             Location/Qualifiers
     source          1..3739
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 32.15 cM"
     gene            1..3739
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /note="shugoshin 2B"
                     /db_xref="GeneID:244495"
                     /db_xref="MGI:MGI:3644562"
     exon            1..233
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     exon            234..359
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             236..3739
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /note="shugoshin like 2b"
                     /codon_start=1
                     /product="Shugoshin 2"
                     /protein_id="NP_001182616.1"
                     /db_xref="CCDS:CCDS57623.1"
                     /db_xref="GeneID:244495"
                     /db_xref="MGI:MGI:3644562"
                     /translation="MEYPGIEVDAVTSGIQRRVKDRIAKTKLSVSLASKIKTKLFNNS
                     SMFRISLKHNNRALARALSKEKENSRKITTEKMQLQKEVEKLNFENTFLRLKLNNLNE
                     KLKEIESHVANNLLAAIETSSLSEFHQSSSFLSANKKQRRSNQCKSAHLPYERVLLTS
                     ENDDDDDDGADDKWNTKCSNRIISKTSPDTTSLVSRQPLSLHQCNLELFLPKEGNQKT
                     CGSGHSEHTSSVDVLPNESHCHSDQSPQSSPSEMKTGPSPNLRRGEKLTLKNITQRKK
                     CVSSTVDILYVSDLENQSISSPGSNWNNEINGHTNETSNNTQRNTECFLGLPSESSSE
                     PYVKRMEQVQKTDNFHFHNTVSEAADVELTATDVGKIVIVSKSNKNQIKKKADCRKET
                     FRKVKGASSDKKRESSKRECKDGSEVGAEKETDESRAKRGSGVLDGRGDSEEPNCISS
                     TEQPSQVNTQKKITPQNSSDQENIQNKKRRRTYMLDEQEEANPFSRHSVKFLQDGKFD
                     LCQKTLHHNLSNPSRQTFVIHKSEKGNLFPNQEDKDTISESLEVTNEFHTADHSIREN
                     VCDHEAQTTLGLRKSVNAQQNLTKKTKQKINRGTKIVSSMKQIYEDNDKDMHFLEKGN
                     FPFQTQADKVTTSGSLEATEEFDTPLFFTRVNGSLRDCETQNVMDLHKQITGIYPAQN
                     ESQMSKNPRQKVNRKTAVISGVNCFSSDKGVHCSEKDKSFLLQKDKDILGTLKDLSES
                     DMPALCNQDSAEPYKSEMLLGLKKHDHDMQPACQGDSKVDKKLRKQANRKTEIISKIT
                     QIHDNDGGSAHDPLNKKLGQKVNISDIISQMNQLYETTIEDGNGFKSSVKDCQGVISC
                     DLGEINSNKKENYDPIQDPCTLVKKTKRKGSCNSGSSLAGDKNRCSLRLTDSSQVSVT
                     LDSGLRHHPNEADTSPGEWTNLPKKQKPIVVSSPGDAFSVSAGKARSNPAKAVSEMTS
                     KLKKRKTHLGCSPETHGPVEITPNTDLTKAVDSQQTEKENYLEKENYLENEKIAKRKP
                     DFCMKVLKPLSQTCSSNIKNSSLDSMCKSSLPLSISSSKNLMLEESSSLESTCIFQVG
                     DDAREKITAGTHNPHRTQKSRPGSRTSLVLVDTSSVSSNTANPENESEEQSSPPRRRK
                     RQCAPLNLTEPSLKRQVWQRC"
     exon            360..535
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     exon            536..613
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     exon            614..699
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     exon            700..941
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     exon            942..3566
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
     exon            3567..3739
                     /gene="Sgo2b"
                     /gene_synonym="EG244495; Gm4975; Sgol2b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcgaggtcc tcaggcaagt gtgggcaccc acagctgaag gggtcgccag gctgcgggga
       61 tagcgaggcc tgcggagccc gaacccttct cagcagctac tcctggcacc tcctgcagcg
      121 gcttggaggg cccggacgct gaggccggac gcggtgctgg ctttggatca gggcgctaac
      181 ctctgttctg cctttgagct cctagctggg cagacggtca cagtagcttt cagaaatgga
      241 gtacccaggg atagaagttg acgctgttac ctctggaatt cagagacgtg tgaaggaccg
      301 aattgcaaag acaaagttga gtgtttctct tgcttcaaag atcaaaacaa aactattcaa
      361 caattcttct atgttcagga tctctctaaa gcacaacaac agagcactag cgcgggccct
      421 tagtaaagag aaagagaact ctcgaaaaat tactaccgaa aagatgcaat tacagaaaga
      481 agtagagaaa ctgaattttg agaatacctt tcttcgctta aagctaaata acttgaatga
      541 gaagcttaaa gagatagaat cacatgtggc caataatttg ttagctgcaa ttgaaacgag
      601 cagtctttct gagttccatc aaagttcttc tttcctgtca gctaacaaga aacaaaggcg
      661 gagtaatcaa tgcaagtctg cacatcttcc atatgaaagg gttctattaa cttcagaaaa
      721 tgatgatgat gatgatgatg gtgctgatga taaatggaat acaaagtgta gcaacagaat
      781 tatatcaaag acctcacctg atactacttc tttggtatca agacaacctt tatccttaca
      841 tcaatgtaat ttggaattat tccttcctaa agaaggtaat cagaaaacat gtggttcagg
      901 tcattcagaa catacttcaa gtgttgatgt acttcctaat gagagccatt gtcactcaga
      961 tcaaagtcct cagagttctc cgagtgagat gaaaactggt ccatctccca accttagaag
     1021 gggagaaaaa ttaacactta aaaatattac tcagaggaag aagtgtgtgt cttcaactgt
     1081 agacatactg tatgtgtcag atttagaaaa ccaatcaata tcaagtccag gatcaaattg
     1141 gaataatgag ataaatggcc ataccaatga aaccagtaat aacacacaaa gaaataccga
     1201 gtgttttctt ggcttacctt ctgaatcttc cagtgagcct tatgtaaagc gcatggagca
     1261 agtgcagaaa actgacaact ttcattttca taacactgtg tctgaagccg ctgatgtgga
     1321 gttaactgct actgatgtag gcaagattgt aatagtttca aagagcaata aaaatcaaat
     1381 taagaaaaag gcagattgta gaaaggagac tttcagaaaa gtgaaaggtg caagctctga
     1441 taaaaagaga gaaagctcaa agagagaatg taaagatggt tcagaagtag gtgctgaaaa
     1501 agagactgat gaaagcagag caaaaagagg ctctggtgtc ctggatggca gaggggattc
     1561 agaagagcca aactgtattt ccagtactga gcagccatct caggtaaaca cgcaaaagaa
     1621 aataaccccc cagaacagct cagatcagga gaacattcaa aataaaaaga ggaggcgaac
     1681 atatatgcta gatgagcaag aggaagcaaa ccctttctcc agacattcag tcaaattcct
     1741 tcaagatggt aaatttgacc tgtgtcagaa aaccctacat cataatttaa gtaacccttc
     1801 tcgacagaca tttgtgattc ataaatcaga aaaaggtaac ttatttccaa atcaagaaga
     1861 taaggacacc atttctgaaa gcctagaagt tacaaatgaa tttcatacag ctgatcattc
     1921 catcagagaa aatgtatgtg accatgaggc tcagacaaca ttgggcttga gaaagtctgt
     1981 caatgctcaa caaaatctaa caaagaagac taagcagaaa ataaatcgag gaacaaaaat
     2041 agtttctagc atgaaacaaa tatatgagga caatgataaa gatatgcact tcctagaaaa
     2101 aggcaacttt cccttccaaa cccaagcaga taaagtaacc accagtggaa gtctagaagc
     2161 tacagaagaa tttgatacac ctcttttctt cacaagagtt aatggaagct tgcgagactg
     2221 tgagacccag aatgttatgg atctgcacaa gcaaattact ggtatatacc ctgctcagaa
     2281 tgagtctcaa atgagcaaaa atcctaggca gaaagtaaat cgcaagacag cagtaatttc
     2341 tggagtgaat tgttttagta gtgacaaagg tgttcattgt tcagaaaagg ataagtcttt
     2401 cttgctacaa aaggataaag acattcttgg aaccttaaaa gacttaagtg agtctgatat
     2461 gcctgctctt tgtaaccaag atagtgcaga gccatataag tctgaaatgc tcttggggtt
     2521 gaaaaaacat gaccatgata tgcagcctgc ttgtcaaggt gattcaaaag tagataagaa
     2581 gcttagaaaa caggcaaatc gaaagacaga aataatttct aaaatcaccc aaatacatga
     2641 caatgatgga ggaagtgcac atgacccact aaataagaag ctcggtcaga aggttaatat
     2701 atcagatatc atttctcaaa tgaaccaact atatgagact actattgaag atgggaatgg
     2761 ctttaaaagc tctgtcaaag attgccaagg tgttataagt tgtgacttgg gggaaatcaa
     2821 cagtaataaa aaggaaaatt atgatccaat tcaagatcct tgcacactgg ttaaaaaaac
     2881 aaagagaaag ggatcgtgta actcagggag cagtttggca ggagataaga acaggtgtag
     2941 tctgcggtta acagattctt cccaggtgtc ggtcacctta gactctggct taagacacca
     3001 tccaaacgaa gcagatacta gtcctggaga gtggactaac ctgccaaaga agcagaaacc
     3061 aatcgttgtg agttcaccgg gagatgcctt ctctgtgagt gcgggaaaag caagaagcaa
     3121 cccagccaaa gcagttagtg aaatgacatc caaattaaag aaaagaaaga ctcatctagg
     3181 ttgttctcct gaaacccatg gaccagtgga gataacaccc aacactgacc tcactaaggc
     3241 tgttgactcc caacagactg agaaggagaa ctatttggaa aaggagaact atttggagaa
     3301 tgagaaaatt gccaagagga agccagactt ctgtatgaag gtgttgaaac ctttatctca
     3361 gacatgttca tctaatataa agaattcttc cttggacagt atgtgtaaga gttcgctacc
     3421 tttgagtatt tcttctagta aaaacctgat gctggaagaa agttcttccc tggagagtac
     3481 atgcatcttt caagttggtg atgatgcacg tgagaagata acggcaggca ctcataatcc
     3541 ccacagaaca caaaagtcta gaccaggtag cagaacgtcc ctggtcttgg tggataccag
     3601 ttctgtttcg agtaacactg ctaaccctga gaatgagtca gaagagcagt cttcaccccc
     3661 gaggagaagg aaaagacagt gcgcccctct caatctgaca gagccgagcc ttaaaaggca
     3721 agtgtggcag cgttgttaa
//
