LOCUS       NM_053196               3228 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus sideroflexin 2 (Sfxn2), mRNA.
ACCESSION   NM_053196
VERSION     NM_053196.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3228)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   2  (bases 1 to 3228)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   3  (bases 1 to 3228)
  AUTHORS   Ye,X., Xu,J., Cheng,C., Yin,G., Zeng,L., Ji,C., Gu,S., Xie,Y. and
            Mao,Y.
  TITLE     Isolation and characterization of a novel human putative
            anemia-related gene homologous to mouse sideroflexin
  JOURNAL   Biochem Genet 41 (3-4), 119-125 (2003)
   PUBMED   12670026
REFERENCE   4  (bases 1 to 3228)
  AUTHORS   Fleming,M.D., Campagna,D.R., Haslett,J.N., Trenor,C.C. 3rd and
            Andrews,N.C.
  TITLE     A mutation in a mitochondrial transmembrane protein is responsible
            for the pleiotropic hematological and skeletal phenotype of
            flexed-tail (f/f) mice
  JOURNAL   Genes Dev 15 (6), 652-657 (2001)
   PUBMED   11274051
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK162407.1, AK150722.1, AC156982.8 and AA189555.1.
            
            On Feb 3, 2006 this sequence version replaced NM_053196.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150722.1, BC019808.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AK162407.1         1-50
            51-1273             AK150722.1         2-1224
            1274-2973           AC156982.8         138703-140402
            2974-3228           AA189555.1         1-255
FEATURES             Location/Qualifiers
     source          1..3228
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 38.96 cM"
     gene            1..3228
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /note="sideroflexin 2"
                     /db_xref="GeneID:94279"
                     /db_xref="MGI:MGI:2137678"
     exon            1..95
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            96..275
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..1083
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /codon_start=1
                     /product="sideroflexin-2"
                     /protein_id="NP_444426.3"
                     /db_xref="CCDS:CCDS29880.1"
                     /db_xref="GeneID:94279"
                     /db_xref="MGI:MGI:2137678"
                     /translation="MEGDLSGFNIDAPRWDQCTFLGRVKHFFNITDPRTVFASEQELD
                     WAKAVVEKSRMGLVPPGTQMEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQVPGGMLI
                     TGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVAT
                     AVGMNMWTKRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNQNELGHSQ
                     RAAAVGIAQVVISRITMAAPGMILLPVIMERLERLHLMKKVKVMHAPLQVLLCGCFLL
                     FMVPVACGLFPQECELSVSYLEPELRDTIKAKYGEQVLFVYFNKGL"
     exon            276..446
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            447..545
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            546..621
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            622..707
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            708..768
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            769..835
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            836..885
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            886..935
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            936..983
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            984..3213
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3188..3193
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3213
                     /gene="Sfxn2"
                     /gene_synonym="F630107H02Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggggtggttc ccgggcctag ccgcgacact tcagttctgc tttcctggtc agcttcgcct
       61 ggtggcagtc gcggggtgca tccctctggg accagtctgt agtttgtgaa caatatggag
      121 ggggatctgt ctggctttaa tattgatgct ccccgctggg accagtgcac tttcctgggg
      181 cgcgtgaagc acttttttaa catcacagat cctcgcacgg tctttgcatc agagcaggag
      241 ctggactggg ccaaggcggt ggtggagaag agcaggatgg gacttgtgcc ccctggcact
      301 cagatggagc agctgctgta tgcgaagaag ctctacgact cggccttcca ccctgacact
      361 ggggagaaga tgaatgtcat tgggcggatg tccttccagg tccctggtgg catgctcatc
      421 acgggcttca tgctccagtt ctacaggaca atgcctgcag tcattttctg gcagtgggtg
      481 aaccagtcct ttaatgcctt ggtcaactac accaacagga atgcagcttc ccccacgtct
      541 gtcaggcaga tggccctctc ctacttcaca gctactacta ctgcggtggc cactgcagtg
      601 ggcatgaaca tgtggacaaa gagagcccca cccttggtgg gccgatgggt gccttttgcc
      661 gctgtggctg ccgctaactg tgtcaatatc ccaatgatgc gacagcagga actcattcag
      721 ggcatctgtg tgaaggacag gaaccaaaat gagcttggcc attctcagag agctgcggct
      781 gtgggcatcg cacaagtggt tatctctcgg atcaccatgg cagcccctgg catgatcctg
      841 ttgcctgtca tcatggagag gctggagaga ctacacctga tgaagaaggt caaagtgatg
      901 cacgcccccc tgcaggtctt gctgtgtggc tgcttcctcc tctttatggt gccagtggcg
      961 tgcggactct tccctcagga atgtgaatta tcagtttcct atctagagcc agagctacgg
     1021 gacaccatca aggccaagta tggagaacaa gtcctctttg tctactttaa taagggtctc
     1081 taagtgctcc gtgcctgcaa ggaccaatcg gtacaccgcg tggaccagct tttccctggc
     1141 agctgtgcat acctgtgtct acattcctct ttgcaataag gtctgaaagc caggctagat
     1201 ggggaataga atagcctcaa tttgggtggg aagatggttc ctgcttctat ataagcacct
     1261 aatttattgg attccagagg gcaaaattca aaaggggatc aaggtggttg gggatgtagc
     1321 ttggttggga gcgtttgcct ggcattcaca aagctgattc aattctttgt gccgtacgat
     1381 tcaggcataa ttttatatgc ttgtgatccc tgtacttaag aggtggtggc aggaggatta
     1441 gaagttcaaa agttgacaga tagtggtggc acacatcttt agattcagga ggcagaggca
     1501 ggctgatttc tgagtgtgag gccagctggt ctacagagct aattccagga tagccagggc
     1561 tacacagaga aatcttttct caaaaaaaaa aaccaaaaaa caaaaaacaa aaaaccacca
     1621 aaacaaatca acaacaacaa caacaccaaa cccaaaaagt tcaaaggtaa ccttagctac
     1681 atggggaatt ccaggatagc ctgagctaga gacttactca aaaaatagag ggagggaaca
     1741 agaacaaggt attttgcctg ctttgtcctt gccccctgac ccttgggacc agaagcagag
     1801 gtcttctcag cagaggttgc tggtgtatgg gaggtgctca cacagtttag gatatttaga
     1861 aatcgagtga tccttgtcca gtcaggacag aggatacact aatctcttcc tcttctcctg
     1921 cttcctcctt ttttgggggg ggggggatag ccctggctgt cctggaactc actctgtaga
     1981 ccagactggc cccgaactca gaaatccacc tgcctctgcc tcccgagtgc tgggattaaa
     2041 ggtgtgcgcc accacgcccg gcttgcttcc tccttcctaa gcaagagaaa catttaccct
     2101 tgcgattctt aaaaaaaaaa gctttttatc attttttaaa acatttttat gggtgggtgt
     2161 tttgctccca tgcatgtctc tgcatgccgt gcccacagag gtcagagagc atgtcagatc
     2221 atctgaaact ggagttacta ctgtgagcca gcctgcggtc aaaccctggt ccttttgaag
     2281 agcagcggca gctcttacct gctgagccct ctttccagct ccttatccag ggagagataa
     2341 aggagctatg tgaatcttct tggggactca tctctactct tccccatgat gccctgactg
     2401 ggctatccca ttgggaatgc ttctagattt gagtttttca agtccttgga gttatttgta
     2461 ctaaaaaaga caaaaacaaa cacaaacaca aaacaaaaac aaaacccatg gacaaatagt
     2521 tcctttcctt ggcccattag gtctcatacc aaagagggct gggacacctc tgagtgggaa
     2581 ttcaccagga ctacagcctt aaaaacatgt aggagagatg cagggcagca cctttaatcc
     2641 tgtaccctct gggcagaggc aggcggatct ctgagatcga ggccagcctg gtctacagag
     2701 tgagttcctg gccagccagg actacacaga gaaaccctgt cttgaaaaga caaggaaaat
     2761 gaaagtgtag ggcaaaccac cattttacgg aggttatgtg gggcatcaag ctctgcgcct
     2821 tggaaaaatg actattctgt cttaatatca tgtccaaatc cacttctggg acctttagct
     2881 gagaggtctc ttctctcatt gccttctctg ttttacaagt caagtccctc actgtgagtg
     2941 ggatgatttc ctgctgcctt ccttccctct gcctgttagg tcacatacca aagattgctg
     3001 agtgctggtg ggatgtggag cctcacttgg acacctcaga caggaagtcc accagggcca
     3061 acaagcctaa ggagggcaca aagggccact ttagttccct gggggactgg cttacctggg
     3121 gtcagtgtgt aatgagtttt gtctggcaag atttgctgat tctgttcaaa cgcaccatta
     3181 tgaattgaat aaactatttg aaagaacatg aaaaaaaaaa aaaaaaaa
//
