LOCUS       NM_011359                804 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus surfactant associated protein C (Sftpc), mRNA.
ACCESSION   NM_011359
VERSION     NM_011359.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 804)
  AUTHORS   Warren,R., Klinkhammer,K., Lyu,H., Knopp,J., Yuan,T., Yao,C.,
            Stripp,B. and De Langhe,S.P.
  TITLE     Cell competition drives bronchiolization and pulmonary fibrosis
  JOURNAL   Nat Commun 15 (1), 10624 (2024)
   PUBMED   39639058
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 804)
  AUTHORS   Jiang,J., Ye,P., Sun,N., Zhu,W., Yang,M., Yu,M., Yu,J., Zhang,H.,
            Gao,Z., Zhang,N., Guo,S., Ji,Y., Li,S., Zhang,C., Miao,S., Chai,M.,
            Liu,W., An,Y., Hong,J., Wei,W., Zhang,S. and Qiu,H.
  TITLE     Yap methylation-induced FGL1 expression suppresses anti-tumor
            immunity and promotes tumor progression in KRAS-driven lung
            adenocarcinoma
  JOURNAL   Cancer Commun (Lond) 44 (11), 1350-1373 (2024)
   PUBMED   39340215
REFERENCE   3  (bases 1 to 804)
  AUTHORS   Kim,B., Huang,Y., Ko,K.P., Zhang,S., Zou,G., Zhang,J., Kim,M.J.,
            Little,D., Ellis,L.V., Paschini,M., Jun,S., Park,K.S., Chen,J.,
            Kim,C. and Park,J.I.
  TITLE     PCLAF-DREAM drives alveolar cell plasticity for lung regeneration
  JOURNAL   Nat Commun 15 (1), 9169 (2024)
   PUBMED   39448571
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 804)
  AUTHORS   He,H., Bell,S.M., Davis,A.K., Zhao,S., Sridharan,A., Na,C.L.,
            Guo,M., Xu,Y., Snowball,J., Swarr,D.T., Zacharias,W.J. and
            Whitsett,J.A.
  TITLE     PRDM3/16 regulate chromatin accessibility required for NKX2-1
            mediated alveolar epithelial differentiation and function
  JOURNAL   Nat Commun 15 (1), 8112 (2024)
   PUBMED   39284798
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 804)
  AUTHORS   Jain,K.G., Liu,Y., Zhao,R., Muire,P.J., Zhang,J., Zang,Q.S. and
            Ji,H.L.
  TITLE     Humanized L184Q Mutated Surfactant Protein C Gene Alters Alveolar
            Type 2 Epithelial Cell Fate
  JOURNAL   Int J Mol Sci 25 (16), 8723 (2024)
   PUBMED   39201410
  REMARK    GeneRIF: Humanized L184Q Mutated Surfactant Protein C Gene Alters
            Alveolar Type 2 Epithelial Cell Fate.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 804)
  AUTHORS   Holmberg,M., Leonardsson,G. and Ny,T.
  TITLE     The species-specific differences in the cAMP regulation of the
            tissue-type plasminogen activator gene between rat, mouse and human
            is caused by a one-nucleotide substitution in the cAMP-responsive
            element of the promoters
  JOURNAL   Eur J Biochem 231 (2), 466-474 (1995)
   PUBMED   7543410
REFERENCE   7  (bases 1 to 804)
  AUTHORS   Cole,T.J., Blendy,J.A., Monaghan,A.P., Krieglstein,K., Schmid,W.,
            Aguzzi,A., Fantuzzi,G., Hummler,E., Unsicker,K. and Schutz,G.
  TITLE     Targeted disruption of the glucocorticoid receptor gene blocks
            adrenergic chromaffin cell development and severely retards lung
            maturation
  JOURNAL   Genes Dev 9 (13), 1608-1621 (1995)
   PUBMED   7628695
REFERENCE   8  (bases 1 to 804)
  AUTHORS   Moore,K.J., D'Amore-Bruno,M.A., Korfhagen,T.R., Glasser,S.W.,
            Whitsett,J.A., Jenkins,N.A. and Copeland,N.G.
  TITLE     Chromosomal localization of three pulmonary surfactant protein
            genes in the mouse
  JOURNAL   Genomics 12 (2), 388-393 (1992)
   PUBMED   1346779
REFERENCE   9  (bases 1 to 804)
  AUTHORS   D'Amore-Bruno,M.A., Wikenheiser,K.A., Carter,J.E., Clark,J.C. and
            Whitsett,J.A.
  TITLE     Sequence, ontogeny, and cellular localization of murine surfactant
            protein B mRNA
  JOURNAL   Am J Physiol 262 (1 Pt 1), L40-L47 (1992)
   PUBMED   1733280
REFERENCE   10 (bases 1 to 804)
  AUTHORS   Glasser,S.W., Korfhagen,T.R., Bruno,M.D., Dey,C. and Whitsett,J.A.
  TITLE     Structure and expression of the pulmonary surfactant protein SP-C
            gene in the mouse
  JOURNAL   J Biol Chem 265 (35), 21986-21991 (1990)
   PUBMED   2254341
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122268.5, BY773034.1, CJ093163.1 and CJ237354.1.
            
            On Aug 21, 2009 this sequence version replaced NM_011359.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB596213.1, CB596575.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC122268.5         148402-148404       c
            4-10                BY773034.1         5-11
            11-560              CJ093163.1         7-556
            561-801             CJ237354.1         273-513
            802-804             AC122268.5         145264-145266       c
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 36.32 cM"
     gene            1..804
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /note="surfactant associated protein C"
                     /db_xref="GeneID:20389"
                     /db_xref="MGI:MGI:109517"
     exon            1..80
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /inference="alignment:Splign:2.1.0"
     exon            81..239
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /inference="alignment:Splign:2.1.0"
     exon            240..362
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /inference="alignment:Splign:2.1.0"
     exon            363..473
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /inference="alignment:Splign:2.1.0"
     exon            474..629
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /inference="alignment:Splign:2.1.0"
     exon            630..804
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      778..783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /note="hexamer: AATAAA"
     polyA_site      804
                     /gene="Sftpc"
                     /gene_synonym="Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5;
                     SPC"
                     /note="major polyA site"
ORIGIN      
        1 gagatgagga gaggagagag agagagaaac cttacaaaat ggacatgagt agcaaagagg
       61 tcctgatgga gagtccaccg gattactcgg caggtcccag gagccagttc cgcatcccct
      121 gctgtcccgt gcacctcaaa cgccttctca tcgtggttgt ggtggtggtc ctcgttgtcg
      181 tggtgattgt aggggctctg ctcatgggcc tccacatgag tcaaaaacat actgagatgg
      241 tccttgagat gagcatcgga gcaccggaaa ctcagaaacg cctagccccg agtgagcgag
      301 cagacaccat cgctaccttt tccatcggct ccactggcat cgttgtgtat gactaccagc
      361 ggctcctgac ggcctataag ccagctccag gaacctactg ctacatcatg aagatggctc
      421 cagagagcat ccctagtctt gaggctttcg ctagaaaact ccagaacttc caggccaagc
      481 cctccacacc cacctctaag ctgggccagg aggaagggca tgatactggt tccgagtccg
      541 attcttccgg gagagacctg gctttcctag gccttgctgt gagcaccctg tgtggagagc
      601 taccactcta ctatatctag catccacagg gtcggtagaa accgcagcgg gacaggaaag
      661 accctccgca aagggtcttt gtcagacaag caggaagctg ctcctgccca gaaaccggtg
      721 gaagtctgta aaggaaaggt gtctctccta cgggccaggg ggatcctatc acaaaagaat
      781 aaagcagcct gattggaaaa caaa
//
