LOCUS       NM_145512               5526 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SFT2 domain containing 2 (Sft2d2), transcript variant
            1, mRNA.
ACCESSION   NM_145512
VERSION     NM_145512.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5526)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5526)
  AUTHORS   Takahashi,Y., Miyata,M., Zheng,P., Imazato,T., Horwitz,A. and
            Smith,J.D.
  TITLE     Identification of cAMP analogue inducible genes in RAW264
            macrophages
  JOURNAL   Biochim Biophys Acta 1492 (2-3), 385-394 (2000)
   PUBMED   11004510
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154142.24.
            
            On Dec 4, 2008 this sequence version replaced NM_145512.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036578.1, SRR1660817.259902.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-194               AC154142.24        175287-175480       c
            195-281             AC154142.24        169295-169381       c
            282-367             AC154142.24        169016-169101       c
            368-449             AC154142.24        166055-166136       c
            450-485             AC154142.24        165017-165052       c
            486-541             AC154142.24        164874-164929       c
            542-571             AC154142.24        163099-163128       c
            572-5526            AC154142.24        155388-160342       c
FEATURES             Location/Qualifiers
     source          1..5526
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 72.51 cM"
     gene            1..5526
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /note="SFT2 domain containing 2"
                     /db_xref="GeneID:108735"
                     /db_xref="MGI:MGI:1917362"
     exon            1..194
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..611
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /note="SFT2 domain-containing protein 2"
                     /codon_start=1
                     /product="vesicle transport protein SFT2B"
                     /protein_id="NP_663487.1"
                     /db_xref="CCDS:CCDS15440.1"
                     /db_xref="GeneID:108735"
                     /db_xref="MGI:MGI:1917362"
                     /translation="MDKLKKVLSGQDTEDRSGLSEVVEASSLSWGTRIKGFIACFALG
                     ILCSVLGTLLLWVPRKGLGLFAVFYTLGNIMSIGSTVFLMGPLKQLKRMFEPTRLIAT
                     ILVLLCFALTLCSAFLWNKGLALIFCILQSLALTWYSLSYIPYARDAVKKCFAVCLA"
     exon            195..281
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     exon            282..367
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     exon            368..449
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     exon            450..485
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     exon            486..541
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     exon            542..571
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     exon            572..5526
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5500..5505
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /note="hexamer: AATAAA"
     polyA_site      5526
                     /gene="Sft2d2"
                     /gene_synonym="2010005O13Rik; cI-45"
                     /note="major polyA site"
ORIGIN      
        1 gccgggcggg caggtgggca ggtgcctggg cggggcgcgc cgtggttggc agcgggcgga
       61 ggggcggcgg ctgcgcaccc cgaagagtgg taggcggagc gaacgccaaa ggcggcggtc
      121 gggaccctga catggacaag ctgaagaaag ttctgagcgg ccaggacacc gaggaccgca
      181 gcggtctgtc cgaggttgtg gaggcgtcgt cgctgagctg gggcaccaga ataaaaggct
      241 tcatcgcatg ctttgctctg ggaatcctgt gctcagtgct ggggactctt ctgctgtggg
      301 tgcccaggaa gggactcggc ctctttgcag tgttttacac cctgggtaac atcatgtcaa
      361 ttgggagtac cgtcttcctc atggggccgc tgaagcagct gaagcgcatg tttgagccta
      421 cgcgtctcat cgccacaatt ctggtgctgc tgtgttttgc acttaccctg tgttctgcct
      481 ttttgtggaa taagggactt gcactcatct tctgtatttt gcagtctttg gccttgacgt
      541 ggtatagcct ttcctatata ccgtatgcaa gggatgccgt gaagaagtgc tttgctgtgt
      601 gtcttgcata acacactgcc agtgtgcagg gagcaccgtg gacggaagct ggtggacaat
      661 tctgtaaatg tcctctaaac ctctgtctca cagacacgtg ccttctgctt gcagcggtgt
      721 gtggcttgca atttggacat ttttgagggt tgcctgtggg aatagtcatg agtcctagac
      781 cctaatgtct gtaacacaat ccgaggctct gtggcttgtg tagacaactc ttcttgtgac
      841 cattaacctc tgggaggtat tccactgact tctcacagag cagctttgtc tggtagcagc
      901 agatcagcct caggagcaac tgattcccag gtggcagcag gaaggtctag cagggcttct
      961 agcggagcag caggaagtac agaattttga agatttgccc ctcaccagga aaaccattgc
     1021 cacagtccct gcacagcgtc ttccctgctg tttgagaaca agtgattctg cccagaccct
     1081 ggagagcctg cccgggatac attgttcctt tccctgcatg gcaccgtctt gctattctga
     1141 actcagctgg ctatgaaata cacttttagt gttcaatgtg gattctttct cttgccctta
     1201 cctcctacgt cttgttttgt cttgtgacac cggttaattg cgagtgaagt agtgacctaa
     1261 aaagctattt cctttcggac aagagccatt agaaagtgaa acatcttcat gttccttgct
     1321 ttgtttattt gccctcatta tttataaatg tttactttct gtcctttgct ggagttgaga
     1381 taaggaaagt acatggaaga aagatccctc gtgggccagc aagaaggcat gcctgccaag
     1441 caacctaaat gctccagcgt tgactctcag cctgcactgg acactagtag tcagcctgta
     1501 ggtgggcatg ctgcagccta gtgcctaacc acacacagcg ttcttgtgtt ggggacctca
     1561 tctggtcctc atgagagcca tatgagttgt ctcaactgca gtcaaggaac cggggctcag
     1621 gttggtttct gtgtcacagc tccagctgtg gcttggctct cagcctctgt tttgacactg
     1681 agtctcctgg catggctctc ctcagagcgt ctgtcgtctc tcataactgt tcctttcatc
     1741 ctcctggcct gtaccttttc tgatttcagc atctatgtca attgtgccac cttctacccg
     1801 ctcccccgtt ttgctttttg gcagctacgt ctgcatctgt aggatggcca gcatcccgtg
     1861 gtccctttca gctgctcagt gcatcccttg catcattagt accctgtctt gacagcttga
     1921 ggtcctggca gtctatgttt gccctttgct cagggccagc cttgacctct gttttttcac
     1981 caccagacca caggaggtga gagcactcat ctctgcggtt gttgccagtt gctgaactgt
     2041 ggctaatgac tgtcttttct tctgagatgg agaactgtgg ataggctgat cagaattagg
     2101 gcagaaggga gctcagtctt tccagattcc agccatgctg ttgaaggcat cgatgaggtc
     2161 ttcagtcagg aagcaaagtt acatgctacc ctctggctgt gtgaggcaca ttcatgtccc
     2221 agaagccttg ggaatcagtt cagggctcag aagggctcag atgtgagaac ggccattggg
     2281 aaatttaggg aaacccatgg atcctagctg acaggaggag tagggtcatt gctgcaagct
     2341 ccaaccgcct tgtagttatg tacctaaaaa gctgacctct ccgtgccctt gtcagggact
     2401 gggcttgagc ccaggtatct tttaaagatg gtatagcaag gatgaagagc ataacagtgt
     2461 gaacatgggc ttagaaaata agcagatcca gatgtggtcc agtcccatgc tggtgatcca
     2521 gatgtggtcc agtcccatgc tggtgatcca gatgtggtcc agtcccatgc tggtggaggc
     2581 cttggaagtt acctaatgtt tggttcctca gtttcactgt ttcctaatag tgggctgaca
     2641 agtcctgctg gctcactgga ggatgccggt ggaagagaat gcatcaaggg cttggggcgc
     2701 atgtggcaca gcaagttggg tctccatgaa ctaactgatg agtgctaaag gtgacaggat
     2761 gggtgcctgc ctgtcagttt gtctagcata ttctgtgtcc atcactgtag actgtcatgc
     2821 attgtctcac tgaatggtca cagtgactgt caggcaacgg ataactgcct tcatcataaa
     2881 gtagtagtgg tctcagaaac tcccaggagc aggggcctca gtgagggtgg tctaggttga
     2941 gatcaagtct ggataaaagg ctttggccta attcctacag cctgtggcca gtttgcttca
     3001 acagtttgtg tctggacaca tttaagcagt ttttggatga ctgtcttcca gaatcttcca
     3061 gactctcaga tttttttttt cagttgcctt aaccctaggt tgtttctgac cctgcttttg
     3121 ctggactata gaaggaagaa agccacttca tatctgctaa agtctcctac caagccagta
     3181 gtattgatta aaagcaactt agtgagtgag gctgaagtgg agaactagcc tctgactgtg
     3241 gctgttggtg ttatctgttt ctcctcccta ccctcaattc ttccccattc acacccatgg
     3301 agcagggcat ccctgtgttg ccaaccaatg gggactgttg agtgatcact gtagaggcag
     3361 tgtggtcctc agccaggctg gtttccaggt gtgggcctga tgctgccttc cctgggctgc
     3421 agtctggagt gcttcactga gaacaccatt gtgccttctg gaccaggaga gtagcttcgg
     3481 atccccttgg ctggtccaac ctctactcca ggctgactgt tgggatgctg tggggtgggg
     3541 gcctgtccac tgaatcctgt ctctcactgt cccttttcac agatcaagcc taaggcagct
     3601 tttgtctctc ctgctcctct gtgtggctgc tgctcagacc ccagctctta ggcatcttgt
     3661 cttggggaag ggtgagatgc atccccagct tggccttttc agtgcttggg tgtctgtttc
     3721 tctcatggtg actttgtgga ttatgcctta attgccaccc cccttccaca tagtcaccgt
     3781 aggctgagag aacaagaaat gaaatcatga attgcattcc atatacgatt actctttaat
     3841 actttggtta gaataaataa ttagcatcgg ggcagtatct gaaatggatg tgaagggcgg
     3901 ggctggtttg gcttttgttg ttgggatccc cgtgagtgac aggttttgcc gtgcacggga
     3961 tgagacttgg tggaatgaat tggtcagtcg aggtgcaccc atggctgtgg atttcctttc
     4021 ctttgtgcac cctctgccta cttcctgact ttactcttcc tctggtaact tctcagtaga
     4081 gtcaattaca accaagccta aaacttattt ttagttaatt aaaaataaaa taaaatcagt
     4141 gtttaaagca gtataaagat gcctgctaga ctttgtggca gtttggtttt tactgttcaa
     4201 gtattttttt ttttaataag tttaataatg tgcttataga taacatcctt ttaaaagtga
     4261 atgaacctta gctgaagttc attgcaaata tacattttcc cctagaaatc taagctgctt
     4321 aggaagtttt attaaaagga ttgcttaggg ggtgatctta aagtacctgc cagttcacgt
     4381 tttgctttga gatcttgtgt gtttttcggc tagcgaaggg ggaacgcagt ggagtttgtt
     4441 taatcccagt ttgctcgggg tggagtgttc tgctttgagt atttccagcc ctgctgtgac
     4501 tgtgggagac atttgaaatt agctggtggc agagccttcc ttcatataag ctgacaatat
     4561 caagtcagat acattctgtc aggagctggt aactgacaag gtagactcgg gatgcacaga
     4621 gtggctttct gcaaactggc tgatctgaaa ccagagaaaa ataggcccag tatataggaa
     4681 ttctgttgaa gctgagaggt cagcccatgg catcagaaca aatgatgaca catgctctgt
     4741 actcagaaca atggcactac atgtctagag tgcctgccta gcatggagcc tgtggttcag
     4801 tccctggaaa tgcatacact gggcatggtg gtgcatgcca atatcccagc acttgggagg
     4861 tagagagagg caggaggacc tagagtatat tggaccctat ctttaaaata ataataataa
     4921 taatcaaaga ccaagtctgg tgtttggacc catgcacatg gctccatctg ttaaatgttc
     4981 aaaaaaaatg tttttttttc tggccttttc attgtctttg ctttaccttg aataaggaag
     5041 gcaaggtaaa caaagcaagc ctccctggac tccgtccttt gtaattctga ctgtgaagtt
     5101 gccagtgagg gtgtgcagaa gccactgatg aaggcactgg cttccttgtg tgggccctgg
     5161 gcacctgggc acactccctg ggagtaaaac caaattcaaa tgccggtggt ggatttgtat
     5221 gcctttagaa cattgtgcct gttctcatac agtgagcttt caaaacattt tgtttaaaaa
     5281 aacaaacaat ttttataatt gtgtaggtat agttgatttt gaatgctacg gattgtataa
     5341 ctgaaatttt atatacaaaa atatattctt gaatactgcc ttttctgtct tgaggatctg
     5401 gttcatgtgg tttcgttttc ctcccttcat agagaaagag tgttgctggg gagagctacc
     5461 tctcccttgc acagctgttt cctccccttt cttttctcca ataaatggta gcattatgat
     5521 ccttaa
//
