LOCUS       NM_030207               4165 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus Sfi1 homolog, spindle assembly associated (yeast)
            (Sfi1), transcript variant 1, mRNA.
ACCESSION   NM_030207 XM_906423 XM_986858
VERSION     NM_030207.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4165)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   2  (bases 1 to 4165)
  AUTHORS   Pezer,Z., Harr,B., Teschke,M., Babiker,H. and Tautz,D.
  TITLE     Divergence patterns of genic copy number variation in natural
            populations of the house mouse (Mus musculus domesticus) reveal
            three conserved genes with major population-specific expansions
  JOURNAL   Genome Res 25 (8), 1114-1124 (2015)
   PUBMED   26149421
  REMARK    GeneRIF: Study showed major differences in gene copy number in
            natural populations. CWC22, SFI1, and HJURP are highly conserved
            genes with the most copy-number variation. They all exhibit
            population-specific expansion patterns, perhaps for local
            adaptations.
REFERENCE   3  (bases 1 to 4165)
  AUTHORS   Alvarez-Dominguez,J.R., Hu,W., Yuan,B., Shi,J., Park,S.S.,
            Gromatzky,A.A., van Oudenaarden,A. and Lodish,H.F.
  TITLE     Global discovery of erythroid long noncoding RNAs reveals novel
            regulators of red cell maturation
  JOURNAL   Blood 123 (4), 570-581 (2014)
   PUBMED   24200680
REFERENCE   4  (bases 1 to 4165)
  AUTHORS   Harrow,J.L., Steward,C.A., Frankish,A., Gilbert,J.G.,
            Gonzalez,J.M., Loveland,J.E., Mudge,J., Sheppard,D., Thomas,M.,
            Trevanion,S. and Wilming,L.G.
  TITLE     The Vertebrate Genome Annotation browser 10 years on
  JOURNAL   Nucleic Acids Res 42 (Database issue), D771-D779 (2014)
   PUBMED   24316575
REFERENCE   5  (bases 1 to 4165)
  AUTHORS   Park,C.S., Rehrauer,H. and Mansuy,I.M.
  TITLE     Genome-wide analysis of H4K5 acetylation associated with fear
            memory in mice
  JOURNAL   BMC Genomics 14, 539 (2013)
   PUBMED   23927422
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4165)
  AUTHORS   Gendrel,A.V., Tang,Y.A., Suzuki,M., Godwin,J., Nesterova,T.B.,
            Greally,J.M., Heard,E. and Brockdorff,N.
  TITLE     Epigenetic functions of smchd1 repress gene clusters on the
            inactive X chromosome and on autosomes
  JOURNAL   Mol Cell Biol 33 (16), 3150-3165 (2013)
   PUBMED   23754746
REFERENCE   7  (bases 1 to 4165)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK639032.1, BY303229.1 and AK133558.1.
            
            On May 12, 2018 this sequence version replaced NM_030207.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133558.1, SRR13948564.3588558.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-140               CK639032.1         1-140
            141-244             BY303229.1         2-105
            245-4165            AK133558.1         53-3973
FEATURES             Location/Qualifiers
     source          1..4165
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 2.19 cM"
     gene            1..4165
                     /gene="Sfi1"
                     /note="Sfi1 homolog, spindle assembly associated (yeast)"
                     /db_xref="GeneID:78887"
                     /db_xref="MGI:MGI:1926137"
     exon            1..244
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            245..360
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     CDS             338..3988
                     /gene="Sfi1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein SFI1 homolog"
                     /codon_start=1
                     /product="protein SFI1 homolog isoform 1"
                     /protein_id="NP_084483.2"
                     /db_xref="CCDS:CCDS36094.1"
                     /db_xref="GeneID:78887"
                     /db_xref="MGI:MGI:1926137"
                     /translation="MEKKIGSRSFRDGVVKKPCSPKTLPLKKSSAFSGIQREPSRSCH
                     SIYYHASQNWTRYRLQELRIRCVARKFLYLWIRVTFGRVTPSRARIFHEQKILQKVFG
                     EWREEWWVSQREWKLCVRADCHYRYYLYNLIFQNWKTFVHQQREMRKRFRIAEHHDTK
                     QKMCQAWKSWLIYMVSRRTKLHMKTTALEFRRQSVLCFWWSKWRWRLGQAHAEHALHA
                     VAVKHRALSLQLQGWLRWQEQLLISQRDRRKEATAVQHYQHWQKQRSLKAWLKYLQIC
                     RVKRWQNEMAVQFHRATVLQIHFCDWQWAWEWRQSLSAHQALVVKLAGRMVLRRAFTH
                     WKHYMLLQAEEAAQREAAAEHRQHYLLYSCFRAFKDNVTQARLQQTRKKLAQQLRDTT
                     LLHRFWNLWQSRIEQREERVQTPSLHAALSHYRVTVLHKCVRVWLRYVHKRQWQQLLR
                     ARADGHFQQRALPAAFYTWYRGWLWHQQRRILHTKAVRFHRGTLEKQVFALWRQKMSQ
                     HRENCLAERMAILQAEQQLLRRFWFVWHQQAAVCQLERQQQAMAIAHHHSGLLRRAFC
                     IWKESTQGFRIERMGRAQAAHFHSAQLLSRAWSMWRECLALRLEEQQKLKCAALHSQC
                     ILLRRALQKWLVYQNRVRSVLREVAARERQHNRQLLWWALHLWRENTMARLDGAKKTS
                     QARVHYSRTLCSKVLVQWREVTSVQIYYRQKEAAALREARKALDRGRLQNWFQHWRFC
                     SQRAAQQRFQLGQAAQHHHWQLLMEAMARWKAHHLGCIRKKFLQRQAAQLLAQRLSRA
                     CFCQWRKQLAVRKQEQWGTARALWLWAFSLQAKVWTAWLGFVLERRRKKARLERAMQA
                     YQQQLLQEGATRLLRFTAGTKAFRQQLQAQQQVQAAHSLHCAVRHCAELWKKKVLGPG
                     KTSQPPAPTTFSKRVTFKDSFLSGHAAEAGDATQETKKLRAPPSQGVLGSLAGAAGEP
                     CHLDLNAARSSRKQPRRPSFLLERLGSQRSPEWYSLGEQQLEKPPEEESTALLGGSSL
                     TRPFLPGVLPNVPGPKLPPTASPGLELLPPSSIMPHAAGGTARVSAKPSIPGPQPWGC
                     PSLPRDLDPQLLPGDSISTRTEPVYGSEATGHTELEAELEGIQQQLQHYQTTKQNLWS
                     CQRQANSLRRWLELSQEEPKSEDLHLEEQVKTELEEVELQVQQLAKELEAQRQPVGTC
                     IARVRALRRALC"
     exon            361..531
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            532..603
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            604..714
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            715..809
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            810..927
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1030
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1187
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1349
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1420
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1513
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1611
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1678
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1809
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1891
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..2070
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..2146
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..2242
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2319
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2422
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2519
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2520..2680
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2681..2755
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2756..2830
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..3007
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3008..3267
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3268..3372
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3373..3556
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3557..3692
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3693..3771
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3772..3883
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     exon            3884..4165
                     /gene="Sfi1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4108..4113
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sfi1"
                     /note="hexamer: AATGAA"
     regulatory      4113..4118
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sfi1"
                     /note="hexamer: AATGAA"
     polyA_site      4128
                     /gene="Sfi1"
                     /note="major polyA site"
     polyA_site      4131
                     /gene="Sfi1"
                     /note="major polyA site"
ORIGIN      
        1 gtgacccgct tctcagaagc gcagaaactt cagggcaaga aaaccgtagg aagccgagct
       61 tagagagaag tctctgtttc ctggaagaca gagcgcacta agctggacag agcagcttcc
      121 ggcgcgggtc gcgttgccgt ggagacgggg gaggagccgc cgtcggcgca gggccggaaa
      181 ctctgggctg gggccctttg ctaccacctc tgtctagcgt ctgctgagga gtcacctccc
      241 tcagttataa gaggaagtta aaaggctttg gttcatcaat aacctagtca caaaaataca
      301 tatcaaccac tggttgaatt tccatcaaga ggaaagaatg gagaagaaga ttggttccag
      361 gtcttttagg gatggtgtgg ttaagaaacc ttgttctcca aagaccctgc ccctcaaaaa
      421 gtcttctgcc ttctctggga tccagaggga gccatctaga agctgccact ctatatacta
      481 tcatgcctca caaaactgga ctcggtaccg attacaagaa cttcgaatca ggtgtgtggc
      541 cagaaagttc ctgtatttgt ggattcgagt gacttttgga agagtgactc cctctagagc
      601 caggattttc catgagcaga aaatattaca gaaggtcttc ggagaatgga gggaagaatg
      661 gtgggtctcc cagagggagt ggaagctctg tgtccgagct gactgtcact acagatacta
      721 cttgtacaac ctgattttcc agaactggaa gacctttgtg caccagcaac gggagatgag
      781 gaagaggttc cgaatagctg agcatcatga tacgaagcag aagatgtgcc aagcctggaa
      841 gtcctggttg atatacatgg tttctcgtag gaccaaactt cacatgaaga ctactgctct
      901 agagtttagg aggcagagtg tcttatgttt ctggtggagc aagtggaggt ggcgactagg
      961 acaagcccat gcagagcacg ctctccatgc agtggctgtg aagcacaggg ccctgagcct
     1021 ccagctgcag ggttggctgc gatggcaaga acagcttcta attagccagc gagataggag
     1081 gaaggaggcc actgctgtgc aacactatca gcactggcag aagcagagat ctctgaaggc
     1141 ttggcttaaa tacctccaaa tctgcagggt gaagagatgg cagaatgaga tggctgtaca
     1201 attccaccgt gctactgtgc tccagataca tttctgtgac tggcagtggg cctgggagtg
     1261 gaggcagagc ttgtctgccc accaggccct ggtggtgaag ctggccggga ggatggtcct
     1321 gcggagggcc tttacacact ggaagcacta catgttgcta caggcagaag aggctgccca
     1381 gcgcgaggca gcagctgaac accgccagca ctacctgctg tattcttgct ttagagcctt
     1441 caaagacaac gtgacccagg cccgactaca gcaaacaaga aagaagcttg ctcagcagct
     1501 gcgtgacact acattgcttc acaggttctg gaacctctgg cagtctcgaa ttgagcagag
     1561 ggaggagagg gtacagaccc cctcattgca tgcagccctg agccactaca gggtgacagt
     1621 cctacacaag tgtgtcaggg tgtggctacg gtatgtgcac aagagacaat ggcagcagtt
     1681 attgcgggcc agagcagatg gtcatttcca gcagcgagca ctgcctgctg ccttctacac
     1741 gtggtacaga ggctggctat ggcaccagca gagacggatc ctgcacacaa aagcagtgcg
     1801 tttccacaga gggacattag agaagcaagt atttgctctc tggaggcaga agatgtctca
     1861 gcatcgagaa aactgcttgg cagagagaat ggctatactg caggcagagc agcagctttt
     1921 gcgtaggttc tggttcgtgt ggcaccagca ggcagcagtg tgtcagctgg agcgacagca
     1981 gcaagccatg gccattgccc accaccacag tggactgctc aggagggctt tctgcatctg
     2041 gaaggaaagc acccaaggat ttaggataga gaggatgggc agggcacagg ctgcgcactt
     2101 ccactctgca cagctcttga gtcgggcctg gagcatgtgg agggagtgcc tggccctgag
     2161 gctggaagag cagcagaaac tgaagtgtgc ggccctgcac agccagtgca tcctgcttcg
     2221 cagggctctg cagaagtggc tggtttacca gaatagggtg aggagtgttc tgcgggaggt
     2281 ggcggccagg gagagacagc acaacaggca gctgctgtgg tgggcgttac atctctggag
     2341 agaaaacacc atggcccgtt tggatggagc caaaaaaacc tctcaagcaa gagttcacta
     2401 cagcaggact ctgtgctcca aggtcctcgt ccagtggcga gaggttactt cagtgcagat
     2461 atattaccga caaaaggagg cagctgccct cagggaggcc cggaaagcac tggacagggg
     2521 tcgtctccag aactggtttc agcactggcg attctgcagc cagagggcag cccagcagag
     2581 attccagctg ggacaggcgg ctcagcatca ccactggcag ctgctgatgg aagcaatggc
     2641 caggtggaag gcacaccatc tggggtgtat cagaaagaag tttctgcaga ggcaagctgc
     2701 ccaactcctg gcacagagac tcagtcgggc ctgcttctgc cagtggagga agcagctggc
     2761 agtccggaag caagaacagt ggggcacagc ccgggccctg tggctctggg ccttctcact
     2821 acaagcaaag gtgtggactg catggctggg cttcgtactt gagaggagga ggaagaaggc
     2881 acggctggaa cgggctatgc aagcctacca gcagcagctc ctacaggagg gtgccacacg
     2941 gcttctgcgc ttcacagctg gtacgaaggc cttccggcag cagctccagg cccagcagca
     3001 ggtccaggca gcccacagcc tccactgtgc agtccgccac tgtgctgagc tctggaaaaa
     3061 gaaggtgctt ggtccaggca agacttctca accaccagca cccaccacat tcagcaagag
     3121 agtgacattt aaggattctt tcctctctgg acatgctgcg gaggctggag atgctaccca
     3181 ggagacaaag aagcttcgag ctcctccatc tcagggagtc ctgggtagtt tggcaggagc
     3241 tgctggggag ccctgccacc tagacctcaa tgcagcccgc tcatcacgga aacagccccg
     3301 acgtccatcc ttcctgcttg agcgtttggg gagtcagagg tccccagagt ggtacagcct
     3361 tggggagcag cagttagaga agcccccaga ggaggaaagc acggctctgc tgggaggctc
     3421 ttccctgaca agacccttcc tacctggggt cctgccgaat gttcctggtc cgaagctgcc
     3481 tcctacggcc agtccaggcc tggagctgct gcctccctcc tccatcatgc cccatgcggc
     3541 aggaggcact gctagggtgt cagcgaagcc cagcatccct gggcctcagc cttgggggtg
     3601 cccgtcctta cccagggacc ttgatcccca actcctccct ggagattcca taagcacccg
     3661 gactgagcct gtttatggct cagaggctac aggccacaca gagcttgagg ctgagttgga
     3721 ggggatccag cagcagttac aacactacca aaccaccaag cagaaccttt ggtcatgcca
     3781 gcgacaagcc aacagcctgc gtaggtggct ggagctaagc caggaggagc cgaaatccga
     3841 ggaccttcac ctagaagagc aggtgaaaac agaactggag gaggtggaac tacaggtcca
     3901 gcagctggct aaggagcttg aggcccagcg tcagcctgtt ggtacatgca ttgctcgtgt
     3961 tcgggccctg agacgggcac tgtgctagtg gcccgtccct gggggatagg tgctatcctt
     4021 cacaaggcct gggacaccct caacaacaaa attcaaagct atggtagttt ttgttttgtt
     4081 ttgtttttta atttcaaaat gtcttgcaat gaaatgaatt actgttcaga agtctcctac
     4141 ttttcataca aaatacggta ctact
//
