LOCUS       NM_025323               1133 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus splicing factor 3B, subunit 6 (Sf3b6), mRNA.
ACCESSION   NM_025323
VERSION     NM_025323.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  AUTHORS   Maserati,M., Dai,X., Walentuk,M. and Mager,J.
  TITLE     Identification of four genes required for mammalian blastocyst
            formation
  JOURNAL   Zygote 22 (3), 331-339 (2014)
   PUBMED   23211737
  REMARK    GeneRIF: Sf3b14 is required for the blastocyst formation.
REFERENCE   3  (bases 1 to 1133)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC019535.1.
            
            On Jun 19, 2003 this sequence version replaced NM_025323.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019535.1, BI101044.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 2.09 cM"
     gene            1..1133
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /note="splicing factor 3B, subunit 6"
                     /db_xref="GeneID:66055"
                     /db_xref="MGI:MGI:1913305"
     exon            1..212
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..560
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /note="pre-mRNA branch site protein p14; SF3B 14 kDa
                     subunit; splicing factor 3B, 14 kDa subunit"
                     /codon_start=1
                     /product="splicing factor 3B subunit 6"
                     /protein_id="NP_079599.1"
                     /db_xref="CCDS:CCDS25791.1"
                     /db_xref="GeneID:66055"
                     /db_xref="MGI:MGI:1913305"
                     /translation="MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGP
                     IRQIRVGNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMD
                     TKKKEEQLKLLKEKYGINTDPPK"
     exon            213..331
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /inference="alignment:Splign:2.1.0"
     exon            332..470
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /inference="alignment:Splign:2.1.0"
     exon            471..1116
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      694..699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /note="hexamer: AATAAA"
     polyA_site      719
                     /gene="Sf3b6"
                     /gene_synonym="0610009D07Rik; 6030419K15Rik; Sf3b14"
                     /note="major polyA site"
ORIGIN      
        1 gcatcttttc taggaagtaa acgcgtccta atttgagacg cggactttcc ggcattgctg
       61 taaaagcttc cggcgctacc tggctgtaaa tactctgtat ctgacgccgt gtcgcccacg
      121 aaggcgatca ggtttagaaa tatccagagg gatcttacgg taacctacat cagcccgcca
      181 agatggcgat gcaagcggct aagagggcga atattcgcct cccacctgaa gtaaatcgga
      241 ttttgtatat aaggaatttg ccatacaaaa tcacagcaga agaaatgtat gatatatttg
      301 ggaaatatgg acctattcgt caaatcagag tagggaatac acctgaaacc agaggaacag
      361 cctatgtggt ctatgaggac atctttgatg ctaagaatgc ctgcgaccac ctatcaggat
      421 tcaacgtttg taacagatac cttgtggttt tgtattacaa tgctaaccgg gcatttcaga
      481 agatggacac caagaagaag gaggagcagc tgaaacttct caaggaaaag tatggcatca
      541 acacagatcc tcccaagtga atgacagcca cgcgtggtcc tggttacctg ttctcttctc
      601 ttccttttta attagtactg aatattgtga tttcttattt gagaactaga atgacttatg
      661 tgaaagtttt ctagcattag aaaatataat gttaataaac ttgtagcttt tttctataat
      721 gtgtcttctg ttaaacttct cacttctttt tcctaatatc agtagaaaac aaatgaggag
      781 aaacacatgt aggttataga tgagctaagg actgaggtgc ttgtgctggg gacgctcggc
      841 ctggggagcc tggctgttag cagtgtaacc tcagtggagt gctgtgttgc tgtgagcaag
      901 acctcaccct accgcctaga ggtcagtctt ctactagcag ccttagggtg aagatgtaga
      961 actctcagct ctgcctgtac catgccagcc tgggtgccat catgataatg gactgggcct
     1021 ctgaacctgt aagccagccc cagttaaatg ttgtccttat aaaacttgcc ttggtcatga
     1081 tgtctgctca cagccttaaa acccttaaaa cactgaaaaa aaaaaaaaaa aaa
//
