LOCUS       NM_029157               1761 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus splicing factor 3a, subunit 3 (Sf3a3), transcript
            variant 1, mRNA.
ACCESSION   NM_029157 XM_620099 XM_896134 XM_911291 XM_921964 XM_974357
            XM_983572 XM_992567 XM_992590 XM_992606
VERSION     NM_029157.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Jin,L., Chen,Y., Crossman,D.K., Datta,A., Vu,T., Mobley,J.A.,
            Basu,M.K., Scarduzio,M., Wang,H., Chang,C. and Datta,P.K.
  TITLE     STRAP regulates alternative splicing fidelity during lineage
            commitment of mouse embryonic stem cells
  JOURNAL   Nat Commun 11 (1), 5941 (2020)
   PUBMED   33230114
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  AUTHORS   Cao,H., Wu,J., Lam,S., Duan,R., Newnham,C., Molday,R.S.,
            Graziotto,J.J., Pierce,E.A. and Hu,J.
  TITLE     Temporal and tissue specific regulation of RP-associated splicing
            factor genes PRPF3, PRPF31 and PRPC8--implications in the
            pathogenesis of RP
  JOURNAL   PLoS One 6 (1), e15860 (2011)
   PUBMED   21283520
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1761)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1761)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606907.10.
            
            On Mar 30, 2023 this sequence version replaced NM_029157.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13862062.21250.1, AK030743.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               AL606907.10        45110-45284         c
            176-223             AL606907.10        44784-44831         c
            224-276             AL606907.10        44396-44448         c
            277-382             AL606907.10        44185-44290         c
            383-455             AL606907.10        43577-43649         c
            456-547             AL606907.10        41681-41772         c
            548-630             AL606907.10        37994-38076         c
            631-769             AL606907.10        37084-37222         c
            770-838             AL606907.10        36361-36429         c
            839-906             AL606907.10        35274-35341         c
            907-1014            AL606907.10        34918-35025         c
            1015-1084           AL606907.10        33052-33121         c
            1085-1249           AL606907.10        31862-32026         c
            1250-1360           AL606907.10        31671-31781         c
            1361-1451           AL606907.10        30551-30641         c
            1452-1507           AL606907.10        28674-28729         c
            1508-1761           AL606907.10        27659-27912         c
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 57.88 cM"
     gene            1..1761
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /note="splicing factor 3a, subunit 3"
                     /db_xref="GeneID:75062"
                     /db_xref="MGI:MGI:1922312"
     exon            1..175
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..1585
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /note="SAP 61; SF3a60; spliceosome-associated protein 61"
                     /codon_start=1
                     /product="splicing factor 3A subunit 3"
                     /protein_id="NP_083433.1"
                     /db_xref="CCDS:CCDS38875.1"
                     /db_xref="GeneID:75062"
                     /db_xref="MGI:MGI:1922312"
                     /translation="METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTR
                     AMQDRYMEVSGNLRDLYDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEI
                     CVPMSVEFEELLKARENPSEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDY
                     ITYLSIFDQLFDIPKERKNAEYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQTDFE
                     KKWDNGTFPGWPKETSSALTHAGAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGG
                     TLEERAQRLFSTKGKSLESLDTSLFAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEIL
                     GEQRQLTHENVQRKQARTGEEREEEEEEQISESESEDEENEIIYNPKNLPLGWDGKPI
                     PYWLYKLHGLNINYNCEICGNYTYRGPKAFQRHFAEWRHAHGMRCLGIPNTAHFANVT
                     QIEDAVSLWAKLKLQKASERWQPDTEEEYEDSSGNVVNKKTYEDLKRQGLL"
     exon            176..223
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            224..276
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            277..382
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            383..455
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            456..547
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            548..630
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            631..769
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            770..838
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            839..906
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1014
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1084
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1249
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1360
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1451
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1507
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1761
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1738..1743
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /note="hexamer: AATAAA"
     polyA_site      1761
                     /gene="Sf3a3"
                     /gene_synonym="4930512K19Rik; 60kDa"
                     /note="major polyA site"
ORIGIN      
        1 gagacgctgg ctgaaaggcg gcaggcggtg tttccggcag tgttagtggt ccgccttgaa
       61 acgccgtggc caagggaaaa tggagacaat tttagagcag caacggcgct atcatgagga
      121 gaaggaacgg cttatggatg ttatggccaa agagatgctt acgaagaagt ccacgcttcg
      181 ggaccagatc aattccgatc accgcactcg ggccatgcaa gataggtaca tggaggtcag
      241 tgggaacctg agggatttgt atgatgataa ggacggactg cggaaggagg agctcaatgc
      301 tatctcagga cccaacgagt tcgctgaatt ctataacaga ctcaagcaga taaaggaatt
      361 ccatcggaag cacccaaatg agatctgtgt gccaatgtca gtggaatttg aggagctgct
      421 gaaggctcga gagaatccaa gtgaagaggc acaaaacttg gtggagttca cagatgaaga
      481 gggatatggt cgctaccttg atctccatga ctgctacctc aaatacatta acctgaaggc
      541 atctgagaag ctggattaca tcacatacct gtccatcttt gaccagttgt ttgacattcc
      601 taaagaaaga aagaatgcag agtacaaaag atacctggag atgctgctgg agtacctaca
      661 ggattacaca gatagagtga agccccttca ggatcagaac gagctctttg ggaagattca
      721 gaccgacttt gagaagaagt gggataatgg cacctttcct ggatggccga aagagacaag
      781 cagcgccctg actcacgcgg gagcccatct tgatctctcc gcattctcct cctgggagga
      841 gttggcatcc ctgggtctgg ataggttgaa atctgcacta ttggcattgg gcctgaagtg
      901 tggcgggacc ctagaagaac gagctcagag gctcttcagc accaaaggaa agtctttgga
      961 gtcactcgac acttctctgt ttgccaaaaa tcccaagtca aagggcacaa aaagagacac
     1021 tgagaggaac aaagacattg ctttcctgga agcccagatc tatgaatacg tggagattct
     1081 cggggaacag cgacagctca ctcatgaaaa tgttcagcgc aagcaagcca ggacaggcga
     1141 ggagcgggag gaggaggagg aggagcagat cagcgagagc gaaagtgagg acgaagagaa
     1201 tgagatcatt tacaacccca agaacctgcc gctgggctgg gacggcaagc ccatccccta
     1261 ctggctgtac aagctccacg gcctgaatat caactacaac tgtgagatct gtgggaacta
     1321 cacctaccga gggcccaagg ccttccagcg gcactttgcg gagtggcgtc atgctcatgg
     1381 catgaggtgt ttgggcatcc caaacactgc ccactttgca aatgtgacac agattgaaga
     1441 tgctgtctcc ttgtgggcca agctgaaact gcagaaggct tcagaacggt ggcagcctga
     1501 caccgaggaa gaatatgaag actccagtgg aaatgttgtg aacaagaaga catacgagga
     1561 tctgaaaaga caagggctgc tctagtgctc ggttccctga gaagcctgag aaaagcttcc
     1621 ccaaccaaat gttcttaaag actttttgct atgtagtatc taccttgtag aaaccttgca
     1681 gattgcagag ttgagatgtg ttttatcttt gttttatatt aaaaagatct gtgggaaaat
     1741 aaagccagcc cttgttttgg a
//
