LOCUS       NM_001403449            3688 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus splicing factor 1 (Sf1), transcript variant 18, mRNA.
ACCESSION   NM_001403449 XM_006531740
VERSION     NM_001403449.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3688)
  AUTHORS   Liu HB, Muhammad T, Guo Y, Li MJ, Sha QQ, Zhang CX, Liu H, Zhao SG,
            Zhao H, Zhang H, Du YZ, Sun K, Liu K, Lu G, Guo XJ, Sha J, Fan HY,
            Gao F and Chen ZJ.
  TITLE     RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator
            in Early Zygotic Genome Activation
  JOURNAL   Adv Sci (Weinh) 6 (15), 1900295 (2019)
   PUBMED   31406667
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3688)
  AUTHORS   Nicol B, Grimm SA, Gruzdev A, Scott GJ, Ray MK and Yao HH.
  TITLE     Genome-wide identification of FOXL2 binding and characterization of
            FOXL2 feminizing action in the fetal gonads
  JOURNAL   Hum Mol Genet 27 (24), 4273-4287 (2018)
   PUBMED   30212841
REFERENCE   3  (bases 1 to 3688)
  AUTHORS   Bowles J, Feng CW, Ineson J, Miles K, Spiller CM, Harley VR,
            Sinclair AH and Koopman P.
  TITLE     Retinoic Acid Antagonizes Testis Development in Mice
  JOURNAL   Cell Rep 24 (5), 1330-1341 (2018)
   PUBMED   30067986
REFERENCE   4  (bases 1 to 3688)
  AUTHORS   Gonen N, Futtner CR, Wood S, Garcia-Moreno SA, Salamone IM, Samson
            SC, Sekido R, Poulat F, Maatouk DM and Lovell-Badge R.
  TITLE     Sex reversal following deletion of a single distal enhancer of Sox9
  JOURNAL   Science 360 (6396), 1469-1473 (2018)
   PUBMED   29903884
REFERENCE   5  (bases 1 to 3688)
  AUTHORS   Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA,
            Charalambous M, Clark AJL and Chan LF.
  TITLE     MRAP deficiency impairs adrenal progenitor cell differentiation and
            gland zonation
  JOURNAL   FASEB J 32 (11), fj201701274RR (2018)
   PUBMED   29879378
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   6  (bases 1 to 3688)
  AUTHORS   Wrehlke C, Wiedemeyer WR, Schmitt-Wrede HP, Mincheva A, Lichter P
            and Wunderlich F.
  TITLE     Genomic organization of mouse gene zfp162
  JOURNAL   DNA Cell Biol 18 (5), 419-428 (1999)
   PUBMED   10360842
REFERENCE   7  (bases 1 to 3688)
  AUTHORS   Vernet C and Artzt K.
  TITLE     STAR, a gene family involved in signal transduction and activation
            of RNA
  JOURNAL   Trends Genet 13 (12), 479-484 (1997)
   PUBMED   9433137
  REMARK    Review article
REFERENCE   8  (bases 1 to 3688)
  AUTHORS   Wrehlke C, Schmitt-Wrede HP, Qiao Z and Wunderlich F.
  TITLE     Enhanced expression in spleen macrophages of the mouse homolog to
            the human putative tumor suppressor gene ZFM1
  JOURNAL   DNA Cell Biol 16 (6), 761-767 (1997)
   PUBMED   9212169
REFERENCE   9  (bases 1 to 3688)
  AUTHORS   Bedford MT, Chan DC and Leder P.
  TITLE     FBP WW domains and the Abl SH3 domain bind to a specific class of
            proline-rich ligands
  JOURNAL   EMBO J 16 (9), 2376-2383 (1997)
   PUBMED   9171351
REFERENCE   10 (bases 1 to 3688)
  AUTHORS   Amson RB, Nemani M, Roperch JP, Israeli D, Bougueleret L, Le Gall
            I, Medhioub M, Linares-Cruz G, Lethrosne F, Pasturaud P, Piouffre
            L, Prieur S, Susini L, Alvaro V, Millasseau P, Guidicelli C, Bui H,
            Massart C, Cazes L, Dufour F, Bruzzoni-Giovanelli H, Owadi H,
            Hennion C, Charpak G, Telerman A et al.
  TITLE     Isolation of 10 differentially expressed cDNAs in p53-induced
            apoptosis: activation of the vertebrate homologue of the drosophila
            seven in absentia gene
  JOURNAL   Proc Natl Acad Sci U S A 93 (9), 3953-3957 (1996)
   PUBMED   8632996
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127556.4 and AC167245.2.
            
            On Mar 30, 2022 this sequence version replaced XM_006531740.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422600.1533956.1,
                                           SRR12282455.28425732.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               AC127556.4         206310-206506
            198-326             AC127556.4         208052-208180
            327-402             AC127556.4         210752-210827
            403-555             AC127556.4         213655-213807
            556-592             AC127556.4         214006-214042
            593-645             AC167245.2         32824-32876
            646-829             AC167245.2         33194-33377
            830-945             AC167245.2         33470-33585
            946-1053            AC167245.2         33687-33794
            1054-1234           AC167245.2         34742-34922
            1235-1508           AC167245.2         35179-35452
            1509-1568           AC167245.2         35718-35777
            1569-1748           AC167245.2         35888-36067
            1749-1953           AC167245.2         36827-37031
            1954-3688           AC167245.2         37465-39199
FEATURES             Location/Qualifiers
     source          1..3688
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.48 cM"
     gene            1..3688
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /note="splicing factor 1"
                     /db_xref="GeneID:22668"
                     /db_xref="MGI:MGI:1095403"
     exon            1..197
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..2083
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /note="isoform 17 is encoded by transcript variant 18;
                     transcription factor ZFM1; zinc finger gene in MEN1 locus;
                     mammalian branch point-binding protein; zinc finger
                     protein 162"
                     /codon_start=1
                     /product="splicing factor 1 isoform 17"
                     /protein_id="NP_001390378.1"
                     /db_xref="GeneID:22668"
                     /db_xref="MGI:MGI:1095403"
                     /translation="MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGL
                     TREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTR
                     KKLEEERHTLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPR
                     GNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKA
                     VEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNT
                     TVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSG
                     PATTPLASAPRPAAPASNPPPPSLMSTTQSRPPWMNSGPSENRPYHGMHGGGPGGPGG
                     GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQY
                     LGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPP
                     PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGTPQMQGNPTM
                     VPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGSDGPSHESEDFPRPLVTLPGRQP
                     QQRPWWTGWFGKAA"
     exon            198..326
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            327..402
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            403..555
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            556..645
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            646..829
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            830..945
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1053
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1234
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1508
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1568
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1748
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1953
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
     exon            1954..3688
                     /gene="Sf1"
                     /gene_synonym="BBP; MZFM; WBP4; Zfp162"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcgtctgg cgccgccgcc gcccgccgcg tgagaggacg ggctccccgc gctcttcagc
       61 cgcgtagtcg ggtcccctcc cccccacctc cagctcccgg aaggttcgtg aaggagaagt
      121 cgccgcggag gacgaggaac cgctgctgcc ggtcccctgg ggcgccatgg cgaccggagc
      181 gaacgccacg ccgctggact tcccaagtaa gaagaggaag aggagccgat ggaaccaaga
      241 cacaatggag cagaagacag tgattccagg catgcctaca gttatacccc ctggactgac
      301 tcgggaacag gaaagagctt acatagtgca actacagata gaagacctga ctcgtaaact
      361 gcgcacagga gacctgggca tcccccctaa ccctgaggac aggtcccctt cccctgaacc
      421 aatctacaac agcgagggga agcggcttaa cactcgagag ttccgtaccc gcaaaaagct
      481 tgaagaggag cggcacaccc ttattacaga gatggttgct ctcaacccag actttaaacc
      541 acctgcagat tacaagcctc cagcaacacg tgtgagcgat aaagtaatga tcccccaaga
      601 cgaatatcca gaaatcaatt ttgtggggct cctaattgga cccagaggga acaccctgaa
      661 gaacattgag aaggaatgca acgccaagat catgattcgg gggaaaggat cagtgaaaga
      721 agggaaagtt gggcgtaaag atggtcagat gttgccaggc gaagatgagc ctcttcatgc
      781 tctagtcact gccaatacga tggagaatgt caaaaaggca gtagaacaga tcagaaacat
      841 cctgaagcag ggtattgaga ccccagagga ccagaacgat ctacggaaaa tgcagcttcg
      901 agagttggct cgcttgaatg gcactctacg ggaagatgat aataggatct taaggccctg
      961 gcagagctca gagacgcgca gcattaccaa tactactgtg tgtaccaagt gtggaggggc
     1021 tggtcacatt gcttctgatt gcaaatttca gaggcctggc gaccctcagt cagctcagga
     1081 taaagcacgg atggataaag aatatttgtc ccttatggct gagctagggg aagctcctgt
     1141 ccctgcatct gtgggctcta cctctgggcc tgccaccacg cccctggcta gtgcaccaag
     1201 acctgctgct cctgccagca acccaccacc accgtctctc atgtctacaa ctcagagccg
     1261 cccaccctgg atgaattctg gtccttcaga gaatcggccc taccatggca tgcatggagg
     1321 tggtcctggt ggtcctggag gtggccccca cagcttccca cacccattac ccagcctgac
     1381 aggtgggcat ggtgggcatc ccatgcagca caacccaaat ggaccaccac caccttggat
     1441 gcagccacca ccaccaccga tgaaccaggg cccccaccca cctgggcacc atggccctcc
     1501 tccaatggat cagtacctgg gaagtacgcc tgtgggctct ggggtctatc gcctgcatca
     1561 aggaaaaggt atgatgccgc cgccgcctat gggcatgatg ccgccgcctc cgccacctcc
     1621 cagtgggcag cccccgcctc ctccctctgg tcctcttcct ccatggcagc agcagcagca
     1681 gcagcctccg ccaccccctc cgcccagcag cagtatggct tccagcaccc ccttgccatg
     1741 gcagcaaaat acgacgacta ccaccacgag cgctggcaca gggtccatcc cgccatggca
     1801 acagcagcag gcggctgccg cagcttctcc aggaacccct cagatgcaag gcaaccccac
     1861 tatggtgccc ctgccccccg gggtccagcc gcctctgccg cccggggccc ctccccctcc
     1921 gccgcctccg ccacctggtt ccgccggcat gatgatccct ccccgcggca gcgatggccc
     1981 gagccatgag agtgaggact ttccgcgccc attggtgacc cttccaggca gacagcctca
     2041 gcagcgcccc tggtggacag gatggttcgg caaagcagcc tgagttattt ttgtggacgg
     2101 aatcggaaca cactggctcc atattgtgaa atttttatta atttttatct ttttcctttg
     2161 ttatttcctt atcttttcct ttcttcagac tccgtccaag gagatgctct ccccggtctt
     2221 ctgctgcaga taggatcctt cccttgtctc cattcctctc ctcccaaagg gagaggggca
     2281 aatggtttag gtacaggctt tggctattaa tgtcaggctt ggtggtggga gtggggggtc
     2341 ctatggttct aattgttgaa gggcttcagc cacattcaaa ataagtaggt ggtttatctt
     2401 tgacatcttt taaagagtct ggataaatct gactcgttgc tcaatagggt ttatttggca
     2461 gtgggattca catcttcctg cactcctgcc agcagtacag ggcacagccc aagccaccat
     2521 aggccagcct ggagtctttt tcatgctctg gtcacccaag ctgcctcaga acccatttgc
     2581 ttctctcctt cctggaaagc ttccctttat gttttatttt gaccccagat gtccagatgt
     2641 tttgcagtgt ctggggcttg tgtcccttgt tcttcgttct gctgctttgc cccttccttc
     2701 cctcttcatg gagtgattat gttgataata atgtgtaatg cgcgttcttt tcactggttt
     2761 atctacagaa atttctctgg gccttttttt ctgtgtttga ttcaacactg cactaagggg
     2821 gaaatgttcc attgaataaa agagcagtgt ggttttccgg gtccgtttct tttcttttaa
     2881 aacctttttc ctgaccatca gcaccaagtt ttacctacct accctggccc cagctcctgc
     2941 atgtgaatgg cttcagcccc tcactttttc tagtttctag ttgatagaac tgaaaagcag
     3001 gctcactcca catttcagga gtctttgtca ttgtgacagc cttttcctgg ggctccgacc
     3061 cccacccaca ttgatgagct ctagatagga tttgtgtctc ctagctgctg cccgacttaa
     3121 ggacctggac ctggggaggc atcagcacta aaggtcacgc taactaatcc tgcttgtcgg
     3181 gcacagagct gctaaaatta aaactgccaa gtggcttttt ttctttctct gctggtggct
     3241 ctcagcctgc caggactgca ggtctagggg agtagtaggg acaaaacgtg gtgccctgtg
     3301 ctgagtggcc acgtctacag agtcttctgc agttctcctg tttagggtac taggaaaatc
     3361 accccttgtg tctttgtgag agccacgtct ttggcagctc atacagctgc tgctgctttg
     3421 tctagaggct tgagggcagt tgctgtctac ccttaggctt cctaaccaag ccctcaacta
     3481 gaggttttcc ctattgtctt taaccttaca gtgtgggggc agggcctggc caccctcttc
     3541 gaccttggct ttacctcatt gcttccctca caatcttggt ttccctggtg ggctcattgg
     3601 gcggttaatt agctctttga agctctggaa gcggcaaagt ggcgctgtgt gggttttaga
     3661 agtaaaatca ataaatgact taaccatg
//
