LOCUS       NM_001300892            1312 bp    mRNA    linear   ROD 22-FEB-2022
DEFINITION  Mus musculus serine (or cysteine) peptidase inhibitor, clade B,
            member 6d (Serpinb6d), transcript variant 2, mRNA.
ACCESSION   NM_001300892 XM_006516672
VERSION     NM_001300892.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman
            GA, Nebert DW and Vasiliou V.
  TITLE     Update of the human and mouse SERPIN gene superfamily
  JOURNAL   Hum Genomics 7, 22 (2013)
   PUBMED   24172014
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  AUTHORS   Charron Y, Madani R, Nef S, Combepine C, Govin J, Khochbin S and
            Vassalli JD.
  TITLE     Expression of serpinb6 serpins in germ and somatic cells of mouse
            gonads
  JOURNAL   Mol Reprod Dev 73 (1), 9-19 (2006)
   PUBMED   16175637
REFERENCE   3  (bases 1 to 1312)
  AUTHORS   Kaiserman D, Knaggs S, Scarff KL, Gillard A, Mirza G, Cadman M,
            McKeone R, Denny P, Cooley J, Benarafa C, Remold-O'Donnell E,
            Ragoussis J and Bird PI.
  TITLE     Comparison of human chromosome 6p25 with mouse chromosome 13
            reveals a greatly expanded ov-serpin gene repertoire in the mouse
  JOURNAL   Genomics 79 (3), 349-362 (2002)
   PUBMED   11863365
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC147559.1 and AK136270.1.
            
            On Jul 16, 2014 this sequence version replaced XM_006516672.1.
            
            Summary: This gene is a member of the large Serpin gene family.
            Many members of this family act as protease inhibitors, and have a
            conserved structure including a reactive center loop (RCL) that can
            act as a bait for protease targets. Unlike some members of this
            large gene family, the protein encoded by this gene is an
            intracellular protein, and lacks an N-terminal signal peptide
            sequence. Alternate splicing results in multiple transcript
            variants. A pseudogene of this gene is found on chromosome 13.
            [provided by RefSeq, Jul 2014].
            
            Transcript Variant: This variant (2) contains an alternate splice
            site in the 5' UTR. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC147559.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1256              BC147559.1         1-1256
            1257-1312           AK136270.1         1414-1469
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 13.94 cM"
     gene            1..1312
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /note="serine (or cysteine) peptidase inhibitor, clade B,
                     member 6d"
                     /db_xref="GeneID:238568"
                     /db_xref="MGI:MGI:2667783"
     exon            1..61
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
     exon            62..236
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..1199
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /note="serine (or cysteine) proteinase inhibitor, clade B,
                     member 6d"
                     /codon_start=1
                     /product="serine (or cysteine) peptidase inhibitor, clade
                     B, member 6d"
                     /protein_id="NP_001287821.1"
                     /db_xref="CCDS:CCDS36631.1"
                     /db_xref="GeneID:238568"
                     /db_xref="MGI:MGI:2667783"
                     /translation="MDPLPKLNTKFAFKLLKALDDDTSKNIFLSPPSIASSLAMTLLG
                     AKENTARQIRQTLSLDKCSSDPCEDIHQDFHLLLNEVNKTDPGIILKTENRLFVEKTF
                     HIKKSFKDASQKFYKAEIEELDFKGDTEQSRQHINTWVTKNTDEKIKDLLSPGSVNSN
                     TRLVLVNDFYFKGYWEKPFNKEDTREMPFRVSKNVVKPVQMMFQKSTFKITYIEEIST
                     KILLLPYAGNKLNMIIMLPDEHVELRMLEKKMTYEKFVEWTSLDKMNEEEVEVFLPRF
                     KLEEIYDMNNVLYKMGMTDAFEEGRADFSGISSKQGLFLSKVIYKAFIEVIEKGTKVA
                     AATDIVMMGASPTTHTFCADHPFIFTHMTEDFMIIGRFSSP"
     exon            237..389
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
     exon            390..507
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
     exon            508..650
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
     exon            651..806
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
     exon            807..1312
                     /gene="Serpinb6d"
                     /gene_synonym="Gm11390; SPI3D"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtgggtca cctttggtgc ctgacatgcc tgacactggg gactcaggag ggcaaggaca
       61 gtctcaccat catggatcct ctgccgaaat taaatactaa atttgccttc aaacttttga
      121 aagcactgga tgacgacacc tcaaaaaata tatttttatc acccccgagc attgcttcat
      181 ccctggccat gaccttattg ggagcaaagg aaaacactgc aaggcagata aggcagacac
      241 tttctttgga taaatgcagc agtgatccat gtgaagatat ccaccaggac ttccatttac
      301 ttctcaatga agtgaacaag actgatcctg ggatcatact caaaacagaa aacaggctct
      361 tcgtggaaaa gacattccat attaaaaaat cttttaaaga tgccagccaa aagttctaca
      421 aagcagagat agaagaactg gactttaagg gtgatacaga gcaatcccga cagcacatca
      481 acacctgggt aaccaaaaac acagacgaaa aaatcaaaga cctgctatct ccaggttcag
      541 tgaattcaaa cactagactg gtccttgtta atgacttcta cttcaaagga tactgggaga
      601 agccatttaa taaagaggac accagggaaa tgcctttcag agtcagcaag aatgtggtga
      661 aacctgtgca aatgatgttt caaaagtcta cctttaagat aacctatata gaagagatat
      721 ccaccaagat tctgttgctt ccctatgctg ggaataagct gaacatgatc atcatgcttc
      781 cagatgaaca tgttgaactt agaatgttgg aaaagaaaat gacttatgag aaatttgtag
      841 agtggacaag tctggacaag atgaatgaag aagaggtgga ggttttcctc ccacgtttta
      901 agctggagga gatctatgac atgaacaatg ttctttacaa gatgggcatg actgatgcct
      961 ttgaggaggg cagagcagac ttttctggaa tatcttccaa gcaaggcttg tttctgtcca
     1021 aggtcatata taaggccttt atagaagtga ttgagaaggg cacaaaggtt gcagctgcca
     1081 cagatattgt gatgatgggt gcatcaccaa ctacccacac tttctgtgct gaccacccct
     1141 ttatttttac ccatatgacc gaagatttta tgatcattgg caggttctcc tctccctaag
     1201 gaaaaggtgt ttctgtcagt attttaccgc tctacatggt ttgcctgtga cccactttat
     1261 cttatccata tgtgcaatga cagttatgaa ataaacggct tcatggcatt gc
//
