LOCUS       NM_201376               1164 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus serine (or cysteine) peptidase inhibitor, clade B
            (ovalbumin), member 3D (Serpinb3d), mRNA.
ACCESSION   NM_201376
VERSION     NM_201376.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1164)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1164)
  AUTHORS   Heit,C., Jackson,B.C., McAndrews,M., Wright,M.W., Thompson,D.C.,
            Silverman,G.A., Nebert,D.W. and Vasiliou,V.
  TITLE     Update of the human and mouse SERPIN gene superfamily
  JOURNAL   Hum Genomics 7 (1), 22 (2013)
   PUBMED   24172014
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1164)
  AUTHORS   Lunardi,F., Villano,G., Perissinotto,E., Agostini,C., Rea,F.,
            Gnoato,M., Bradaschia,A., Valente,M., Pontisso,P. and Calabrese,F.
  TITLE     Overexpression of SERPIN B3 promotes epithelial proliferation and
            lung fibrosis in mice
  JOURNAL   Lab Invest 91 (6), 945-954 (2011)
   PUBMED   21403642
  REMARK    GeneRIF: Overexpression of SERPIN B3 promotes epithelial
            proliferation and lung fibrosis in mice.
REFERENCE   4  (bases 1 to 1164)
  AUTHORS   Askew,D.J., Askew,Y.S., Kato,Y., Turner,R.F., Dewar,K., Lehoczky,J.
            and Silverman,G.A.
  TITLE     Comparative genomic analysis of the clade B serpin cluster at human
            chromosome 18q21: amplification within the mouse squamous cell
            carcinoma antigen gene locus
  JOURNAL   Genomics 84 (1), 176-184 (2004)
   PUBMED   15203215
REFERENCE   5  (bases 1 to 1164)
  AUTHORS   Askew,D.J., Askew,Y.S., Kato,Y., Luke,C.J., Pak,S.C., Bromme,D. and
            Silverman,G.A.
  TITLE     The amplified mouse squamous cell carcinoma antigen gene locus
            contains a serpin (Serpinb3b) that inhibits both papain-like
            cysteine and trypsin-like serine proteinases
  JOURNAL   Genomics 84 (1), 166-175 (2004)
   PUBMED   15203214
REFERENCE   6  (bases 1 to 1164)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY367776.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY367776.1, BC138290.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1164
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="BALB/c"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 50.34 cM"
     gene            1..1164
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /note="serine (or cysteine) peptidase inhibitor, clade B
                     (ovalbumin), member 3D"
                     /db_xref="GeneID:394252"
                     /db_xref="MGI:MGI:2683295"
     CDS             1..1164
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /note="serine proteinase inhibitor B3-like 1; serine (or
                     cysteine) proteinase inhibitor, clade B (ovalbumin),
                     member 3D"
                     /codon_start=1
                     /product="serpin B3"
                     /protein_id="NP_958764.1"
                     /db_xref="CCDS:CCDS15215.1"
                     /db_xref="GeneID:394252"
                     /db_xref="MGI:MGI:2683295"
                     /translation="MDLFAVATTKFTLELYRQLRESDNNIFYSPISMMRTLAMLLLGA
                     KANTEQQIKKVLHFNETTKKTTEKSAESHDEENVHQQFQMLMTQLNKFNNAYDLKVPN
                     SIYGAKDFPFLQTFLKDIRKYYQANVESLDFAHAAEESQKKINSWMARQTNGKIKDLF
                     PSGSLNSSTILVLVNAVYFKGQWNHKFDEKHTREEKFWLNKNTSKPVQMMKQRNKFNF
                     IFLENVQAKIVEIPYKGKELSMFVLLPVEIDGLKKFEEQLTADKLLQWTRAENMHMTE
                     LYLSLPQFKVEEKYDLRVPLEHMGMVDAFDPQKADFSGMSNSQGLVVSKVLHKSFVEV
                     NEEGAEAATAMSVESRSLSVPKPNDFSCNHPFLFVMKQNKTNSILFFGRVSSP"
     exon            1..162
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            163..219
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            220..342
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            343..460
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            461..603
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            604..759
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            760..1164
                     /gene="Serpinb3d"
                     /gene_synonym="Serpinb3l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggatttgt ttgctgtagc cactactaaa ttcacacttg agctgtacag gcagctcaga
       61 gaatcagaca acaacatctt ctattccccc atcagcatga tgagaacatt agcaatgctt
      121 ctgcttggag ccaaagcaaa cactgaacaa caaattaaga aggttcttca tttcaatgaa
      181 accacaaaga aaacaacaga aaaatctgca gaatctcatg atgaagaaaa tgtgcatcaa
      241 caatttcaaa tgcttatgac tcagttaaac aaattcaata atgcttatga cctaaaggtt
      301 cccaacagta tctatggagc aaaggatttc ccatttctcc agacattttt gaaagacatt
      361 aggaaatatt accaagctaa cgtggaatca cttgattttg cacatgcagc tgaggaaagc
      421 caaaagaaga ttaattcctg gatggcaagg caaacaaatg gaaaaatcaa ggacttattt
      481 cctagtggga gcctgaacag tagcactata ctggttctgg tgaatgcagt gtatttcaaa
      541 ggacaatgga atcacaaatt tgatgaaaag cataccagag aagaaaagtt ttggctgaac
      601 aagaacacaa gtaaacctgt ccagatgatg aaacaaagaa acaaatttaa cttcatcttc
      661 ctggagaatg tgcaggccaa gattgtggaa ataccataca aaggcaaaga gctaagtatg
      721 tttgtcctgc tgccagtgga aatcgatgga ctgaagaagt ttgaagaaca actcactgct
      781 gacaagttac tacagtggac aagagcagag aatatgcata tgaccgagtt gtatttatct
      841 ttgcctcagt tcaaagtgga agagaagtat gatctccgag ttccattgga acacatgggg
      901 atggtcgacg cctttgatcc acagaaggct gacttctctg gcatgagcaa tagtcaaggt
      961 ctcgtggtgt ctaaagtttt acacaagtcc tttgtggagg taaatgaaga gggtgcagaa
     1021 gcagccactg ccatgagtgt ggaatctcgc tcattatctg taccaaagcc caatgatttc
     1081 tcttgtaatc accctttcct atttgttatg aagcaaaaca agaccaatag catcctcttc
     1141 tttggcagag tgtcttcccc ttaa
//
