LOCUS       NM_001382372            2436 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus serine (or cysteine) peptidase inhibitor, clade A
            (alpha-1 antiproteinase, antitrypsin), member 7 (Serpina7),
            transcript variant 3, mRNA.
ACCESSION   NM_001382372
VERSION     NM_001382372.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2436)
  AUTHORS   Shigesawa,I., Nakamura,A., Yamauchi,Y., Kawata,S., Miyazaki,A.,
            Nomoto,H., Kameda,H., Terauchi,Y. and Atsumi,T.
  TITLE     Effects of glucokinase haploinsufficiency on the pancreatic
            beta-cell mass and function of long-term high-fat, high-sucrose
            diet-fed mice
  JOURNAL   J Diabetes Investig 15 (12), 1732-1742 (2024)
   PUBMED   39305123
REFERENCE   2  (bases 1 to 2436)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2436)
  AUTHORS   Pehrson,J.R., Changolkar,L.N., Costanzi,C. and Leu,N.A.
  TITLE     Mice without macroH2A histone variants
  JOURNAL   Mol Cell Biol 34 (24), 4523-4533 (2014)
   PUBMED   25312643
REFERENCE   4  (bases 1 to 2436)
  AUTHORS   Heit,C., Jackson,B.C., McAndrews,M., Wright,M.W., Thompson,D.C.,
            Silverman,G.A., Nebert,D.W. and Vasiliou,V.
  TITLE     Update of the human and mouse SERPIN gene superfamily
  JOURNAL   Hum Genomics 7 (1), 22 (2013)
   PUBMED   24172014
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2436)
  AUTHORS   Yan,Z., Yan,H. and Ou,H.
  TITLE     Human thyroxine binding globulin (TBG) promoter directs efficient
            and sustaining transgene expression in liver-specific pattern
  JOURNAL   Gene 506 (2), 289-294 (2012)
   PUBMED   22820390
  REMARK    GeneRIF: the TBG promoter has a role in sustaining transgene
            expression in liver-specific pattern
REFERENCE   6  (bases 1 to 2436)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732419.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189682.57814.1,
                                           ERR2680379.195384.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AL732419.6         40243-40274         c
            33-126              AL732419.6         38860-38953         c
            127-774             AL732419.6         38126-38773         c
            775-1048            AL732419.6         37005-37278         c
            1049-1196           AL732419.6         36262-36409         c
            1197-2436           AL732419.6         34304-35543         c
FEATURES             Location/Qualifiers
     source          1..2436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 61.23 cM"
     gene            1..2436
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /note="serine (or cysteine) peptidase inhibitor, clade A
                     (alpha-1 antiproteinase, antitrypsin), member 7"
                     /db_xref="GeneID:331535"
                     /db_xref="MGI:MGI:3041197"
     exon            1..32
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /inference="alignment:Splign:2.1.0"
     exon            33..126
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /inference="alignment:Splign:2.1.0"
     exon            127..774
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /inference="alignment:Splign:2.1.0"
     exon            775..1048
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1196
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..2436
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1442..1447
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /note="hexamer: AATAAA"
     polyA_site      1464
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /note="major polyA site"
     regulatory      2413..2418
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /note="hexamer: AATAAA"
     polyA_site      2436
                     /gene="Serpina7"
                     /gene_synonym="C730040N12Rik; Tbg"
                     /note="major polyA site"
ORIGIN      
        1 gagagatgca agtggcttct tgggcatgtg ctacatgtca ctggtcttta gtgaggagag
       61 agactactgc tccttatttc ttgctgaaca caccatcaaa tacttgcttt agttttataa
      121 atcaagatca tcttcattcc agaatgtcag tgttcttcta tctgtttgtc ttggtatttg
      181 ggcttcaggc tacaatccat tgtgcaccac ataacagctc tgaaggcaaa gtaacgacct
      241 gtcatttgcc ccaacaaaat gccactctct ataagatgcc atctatcaat gctgactttg
      301 cattcagtct gtatcggagg ctctctgtgg agaacccaga tttgaacatc ttcttctccc
      361 ctgtgagcat atctgttgct ttagccatgc tttcttttgg atctggctct agcacccaaa
      421 cacagattct ggaggtgttg gggtttaacc tcacagatac tcccgtgaca gaattacaac
      481 agggcttcca acatttgatc tgttcattga atttcccaaa gaatgaactg gaattgcaga
      541 tgggaaatgc agttttcatt ggacagcagc tgaaaccatt ggcaaagttt ttggatgatg
      601 tcaagaccct ctatgaaact gaagtctttt ctactgactt ctccaatgtt tctgcagccc
      661 agcacaagat caacagttat gtggagaagc aaaccaaagg gaaaattgta ggcttaattc
      721 aaggcctcaa actgaatatt atcatgattc tggtgaacta tattcatttc agagcccagt
      781 gggcaaatcc tttccgtgta tctaaaactg aagagagttc caacttctca gtggacaaga
      841 gcaccacagt acaagtgccc atgatgcacc agctagaaca atactatcat tacgtggata
      901 tggagctgaa ttgtacagta cttcaaatgg actatagtga gaacgccctg gcactttttg
      961 tccttccaaa agagggacac atggaatggg tagaagcagc catgtcatct aagacactga
     1021 agaagtggaa ctatttactg cagaaaggat gggttgaatt gtttgttcca aagttttcta
     1081 tttctgccac atatgacctt ggaagcacac ttcagaagat gggtatgagg gatgcctttg
     1141 ctgaaagtgc tgactttcct ggaataacag aagacagtgg tctaaaactt tcctatgctt
     1201 ttcacaaggc tgtgctacac attggtgaag agggaactaa agagggagct tctcctgaag
     1261 ttgggtctct ggatcagcag gaagtacctc ctcttcaccc tgttatccga ttggatagag
     1321 cattcttact gatgattttg gagaaaagaa ccagaagtgt tctcttttta gggaaacttg
     1381 ttaacccaac aaaacagtaa ttgacgaaga gtccattgag tatgtacata ttataatagg
     1441 aaataaatgg atagcataac ttaatgtact tgctatggac ttggacttta tttcatttgt
     1501 gcaagtgata aaagtggacc tcctcagaag tccattggct gtagaagaag ctaatcctgt
     1561 gaccaaacat gcagatagtc aatgagtgat tgttatccaa aactacaaaa aggatcgatg
     1621 ttggtaggtc tttgtaaagc tggccatgag ttagctaagt gtagaatttt tgactggggg
     1681 tacaaatgct tttggatgta tcttttggac aatagttgca atacaggtca agtctttgca
     1741 ttacactatt ccaatagtat gatcaatgaa cacacaaatg aggtggcttg tatatatcac
     1801 cttcaaaata acctctgctc tttctacctg tgattttggc tattgctaaa tttttctttt
     1861 taaaaaaata aaacttctct tactatacta tcaagtcata aactgagtac tttcaactag
     1921 tgttgcagct tttgtgacct aacatgtatt caacaacaaa ccagggtgaa ataaattctt
     1981 cacacaagcc cacatcatca ctagcagatg ccattgtgct aattcataag ctattgatga
     2041 aagagggaca gatcatttgc atcatatgct atattcatta tttttatatt ccttttaaaa
     2101 tatctttctc ctttctctca tggaaatttc ctggttatcc tggtttcttt tttgtctgta
     2161 gtcctcaata aaatatgata ttttgtgtca ccagaacatc ctctgcctag gtatgccata
     2221 ctatcttcac ctaccgaagt agatttaatc tcaaatttat gtattcaagt accttgtatt
     2281 agaatttgga acacaaataa caaattgaga attaattatg aagtagccaa attctatccc
     2341 acaatatttc acttacagaa aatgagcaac aaacatgtaa gtactatgta ggtttgactc
     2401 catatgaata taaataaaat atgtttgcaa aataaa
//
