LOCUS       NM_001101472            1999 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus serine (or cysteine) peptidase inhibitor, clade A
            (alpha-1 antiproteinase, antitrypsin), member 3J (Serpina3j), mRNA.
ACCESSION   NM_001101472 XM_138240 XM_910293
VERSION     NM_001101472.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1999)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1999)
  AUTHORS   Heit,C., Jackson,B.C., McAndrews,M., Wright,M.W., Thompson,D.C.,
            Silverman,G.A., Nebert,D.W. and Vasiliou,V.
  TITLE     Update of the human and mouse SERPIN gene superfamily
  JOURNAL   Hum Genomics 7 (1), 22 (2013)
   PUBMED   24172014
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1999)
  AUTHORS   Forsyth,S., Horvath,A. and Coughlin,P.
  TITLE     A review and comparison of the murine alpha1-antitrypsin and
            alpha1-antichymotrypsin multigene clusters with the human clade A
            serpins
  JOURNAL   Genomics 81 (3), 336-345 (2003)
   PUBMED   12659817
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117194.3.
            
            On Oct 31, 2008 this sequence version replaced NM_001101472.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849383,
                              SAMN01164137 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-637               AC117194.3         161324-161960       c
            638-911             AC117194.3         158975-159248       c
            912-1062            AC117194.3         157903-158053       c
            1063-1999           AC117194.3         155944-156880       c
FEATURES             Location/Qualifiers
     source          1..1999
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 53.92 cM"
     gene            1..1999
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /note="serine (or cysteine) peptidase inhibitor, clade A
                     (alpha-1 antiproteinase, antitrypsin), member 3J"
                     /db_xref="GeneID:238395"
                     /db_xref="MGI:MGI:2182843"
     CDS             1..1263
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /note="serine (or cysteine) proteinase inhibitor, clade A
                     (alpha-1 antiproteinase, antitrypsin), member 3J"
                     /codon_start=1
                     /product="serine (or cysteine) peptidase inhibitor, clade
                     A (alpha-1 antiproteinase, antitrypsin), member 3J
                     precursor"
                     /protein_id="NP_001094942.1"
                     /db_xref="CCDS:CCDS49158.1"
                     /db_xref="GeneID:238395"
                     /db_xref="MGI:MGI:2182843"
                     /translation="MAFIAALGLLMAGICPAVLCCPEDTLGKHTPVQKDRDHETQLDS
                     LTLASINTDFAFSLYKKLALKNPHKNFVFSPLSITIALASLSLGAKGNTLEEILEGLK
                     FNLTETPEADIHQGFGHLLQRLSQPGDQVQISTGNSMVVEKHLQILAEFKEKARALYH
                     TEVFTADFQQPREARKLLNDYVSNQTQGMIKELVSDLEERTSMVMTNFALFNGKWNMT
                     FDPYETFMGTFIEDRRTPVKVSMMKMKELRAPYFRDEKMKCTVVELNYKGNGKAMFIL
                     PDQGKMKQVEASLQPATLRGWRKSLRPRMIDELYLPKFSISKNYRLENILPELGIKEV
                     FSTQADLSGISGGKDVRVSRMFHSAALDMTETGTEARATTRDKYDFLSTKSNPTVVNL
                     NTPFLFCVLHSDSENIDFMGKINNPAQN"
     exon            1..637
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /inference="alignment:Splign:2.1.0"
     exon            638..911
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1062
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1999
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1978..1983
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /note="hexamer: AATAAA"
     polyA_site      1993
                     /gene="Serpina3j"
                     /gene_synonym="EG238395; Gm4931"
                     /note="major polyA site"
ORIGIN      
        1 atggccttca ttgcagctct ggggctcttg atggctggga tctgccctgc tgtcctctgc
       61 tgtccagagg acacattagg aaagcacact ccagtccaga aagacagaga ccatgaaaca
      121 caactggaca gtcttacatt ggcctccatc aacactgact ttgccttcag cctctacaag
      181 aagctggctt tgaagaatcc acataaaaat tttgtcttct ccccacttag catcacaatt
      241 gccttggcct ccctgtccct gggagcaaag ggcaacactc tggaagagat tctagaaggt
      301 ctcaagttca atctgacaga gacccctgag gcagacatcc accagggctt tgggcacctc
      361 ctacagaggc tcagtcagcc aggggaccag gtacagatca gcacaggcaa ttcaatggtt
      421 gttgaaaagc acctgcagat cctggcagag ttcaaggaga aggcaagggc tttgtaccac
      481 actgaggtct tcacagcaga cttccagcag cctcgtgagg ccagaaagct cctcaatgac
      541 tatgtgagca atcagacgca ggggatgatc aaggaactgg tctcagacct ggaggagagg
      601 acatccatgg tgatgacgaa ttttgccctc tttaacggta aatggaacat gacatttgac
      661 ccttatgaaa cgttcatggg gacattcata gaggacagga ggacacccgt gaaggtgtcc
      721 atgatgaaaa tgaaggaact gagggcaccc tacttccggg atgagaaaat gaaatgcact
      781 gtggtggagc tgaactacaa aggcaatggc aaggccatgt tcatcctccc tgaccagggc
      841 aagatgaagc aggtggaagc cagcttacaa ccagcaactc tgaggggatg gaggaaatct
      901 ttgaggccca ggatgataga tgagctctac ctacccaagt tctccatatc caaaaactac
      961 agactggaga acatccttcc agaactgggt atcaaggaag tcttctccac acaggctgac
     1021 ctgtcaggga tttcaggagg caaggatgta agagtctctc ggatgtttca cagcgctgcg
     1081 ctggacatga ctgagacagg cacagaagcc cgtgccacca caagagacaa atatgacttc
     1141 ctgtccacta aaagcaaccc tacagttgtt aaccttaaca caccattcct gttctgtgtt
     1201 ttacactcag attctgagaa tatcgacttt atgggcaaga tcaacaaccc tgcacaaaac
     1261 tagaactccc caaggggtgg gtcttcttcc cagtttcaaa gactgagtct aaagatgctt
     1321 ttcaggttcc atcctctgac tggctatggc atgcttataa ttgttcagtg accttgatca
     1381 actttagtgg tcacacattc acaggagctt gaggatggtc tgggtcaggc tccctgtctt
     1441 cttggcaact ctagctcata ttcctgagcc taaaacctgt ctttcttcca ttttcctgct
     1501 tatttccctg tatctgcctc tacccaaaag cctgagccct gacaggtagg tgctttccca
     1561 atttgggctc tggttttgtc tgctttggct tctgtagcat taatggggcc atctatgtaa
     1621 gcttataggc caacccatga gaacaacagg ttcaggaaca agatgggaac ttgctgccct
     1681 gtgtctattg gcagcatctg gaacacgtgg tggccagttc tgtctcactc tttctctacc
     1741 ataggatctg tcacctagtg accagtgcag agtctctgga tcctgctcac agattggagt
     1801 cctccctcct gcagctgcat ggggtctgtt ggtcggaccc gagtctcttc ccccctagca
     1861 ttcctgctca gggcagagtg gtagcctttc ccctaacttc ccagctgacc gatctcacag
     1921 gacagatgga cacttccacc ttcatcaccc aaaatgaaaa ggcaggagca aaggatgaat
     1981 aaacgtatac ctgcacaga
//
