LOCUS       NM_001166350            1461 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus serine (or cysteine) peptidase inhibitor, clade A
            (alpha-1 antiproteinase, antitrypsin), member 11 (Serpina11),
            transcript variant 2, mRNA.
ACCESSION   NM_001166350
VERSION     NM_001166350.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1461)
  AUTHORS   Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman
            GA, Nebert DW and Vasiliou V.
  TITLE     Update of the human and mouse SERPIN gene superfamily
  JOURNAL   Hum Genomics 7 (1), 22 (2013)
   PUBMED   24172014
  REMARK    Review article
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY730795.1, AK149420.1 and BB806208.1.
            
            [WARNING] On May 1, 2024 this sequence was replaced by
            NM_001166350.2.
            
            Transcript Variant: This variant (2) uses a different splice site
            for its first exon which results in the use of a downstream start
            codon, compared to variant 1. The resulting protein (isoform 2) has
            a shorter N-terminus when it is compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK149420.1, SRR5189673.86012.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-464               BY730795.1         1-464
            465-1450            AK149420.1         443-1428
            1451-1461           BB806208.1         370-380
FEATURES             Location/Qualifiers
     source          1..1461
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 52.98 cM"
     gene            1..1461
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /note="serine (or cysteine) peptidase inhibitor, clade A
                     (alpha-1 antiproteinase, antitrypsin), member 11"
                     /db_xref="GeneID:380780"
                     /db_xref="MGI:MGI:2685741"
     exon            1..69
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..1347
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; serine (or cysteine) proteinase inhibitor,
                     clade A (alpha-1 antiproteinase, antitrypsin), member 11;
                     serine (or cysteine) proteinase inhibitor, clade A, member
                     11; serpin A11"
                     /codon_start=1
                     /product="serpin A11 isoform 2 precursor"
                     /protein_id="NP_001159822.1"
                     /db_xref="CCDS:CCDS56860.1"
                     /db_xref="GeneID:380780"
                     /db_xref="MGI:MGI:2685741"
                     /translation="MMGPVWLWLWLLVAEVLLPVHCQPFSAHGDKSLGASQPASHQSL
                     EPAPAYHKVTPTITNFALRLYKQLAEEVAGNILFSPVSLSSSLALLSLGAHADTQTQI
                     LESLGFNLTETPAADVHRGFQSLLHTLDLPSPKLELKLGHFLFLDRQLKPQQRFLDSA
                     KELYGALAFSANFTEAAATGQQINDLVRKQTYGQVVGCLPEFSHDTLMVLLNYIFFKA
                     KCKHPFDRYQTRKQESFSLDQRTPLRIPMMRQKEMHRFLYDQEASCTVLQIEYSGTAL
                     LLLVLPDPGKMQQVEAALQPETLRRWGQRFLPSLLDLHLPRFSISATYNLEEILPLIG
                     LGNLFDMEADLSGIMGQLNKTVSRVSHKAIVDMNEKGTEAAAASGLLSQPPALNMTSA
                     PQAHYNRPFLLLLWEVTTQSLLFLGKVVNPAAG"
     exon            70..721
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /inference="alignment:Splign:2.1.0"
     exon            722..995
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1143
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1461
                     /gene="Serpina11"
                     /gene_synonym="Gm895"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacactatca ccctgtgggc aggaggcatt acgggactgt ggagctgggc ccacctgggt
       61 gacttctcta tgatggggcc agtgtggctg tggctgtggc tgctggtagc cgaggtcctg
      121 cttcctgtcc attgtcagcc attttctgcc catggagata agagtctggg ggcatctcaa
      181 ccagccagtc accagtccct ggagccagca cccgcctatc acaaggtcac acccaccatt
      241 acgaattttg ctttgcgtct atacaagcaa ctagcagagg aagtagcggg aaacatcctt
      301 ttctcccctg tgagcctctc cagcagcctg gctctgctgt ctcttggggc acatgctgac
      361 acccagactc aaattctgga gagcctgggc ttcaacctca cagagacccc agcagctgac
      421 gtccaccggg gtttccagag cctcctgcac actcttgacc tccccagccc caaactggaa
      481 ctgaaactgg gacatttcct gttcctagac agacagctga agcctcagca acgttttctg
      541 gacagtgcca aggaactgta tggagctctg gccttttctg ccaacttcac agaagcagct
      601 gccacagggc agcagatcaa tgacctagtg aggaagcaga cctacgggca ggtggtgggc
      661 tgtctcccgg agttcagcca tgacactctc atggttctct tgaactacat cttcttcaaa
      721 gccaagtgca agcatccctt tgatcgctac cagacccgga agcaggagag cttctccctg
      781 gaccagagga cgccactccg aattcccatg atgcgacaga aggaaatgca caggttcctg
      841 tacgaccagg aggcgtcgtg cactgtcctc cagatcgagt acagtggcac cgccttgctg
      901 ctgctggtcc tccctgaccc tgggaagatg cagcaggtag aggctgccct ccagccagag
      961 acgctgagaa ggtggggcca gcggttcctg cccagtctgt tggatttgca cctgccaagg
     1021 ttttcaattt ccgcaactta caacctggaa gagatcctgc ccctcattgg tcttggcaac
     1081 ctattcgaca tggaagctga cttatcagga attatggggc aactcaacaa aactgtctcc
     1141 agggtgtcac acaaggccat cgtggacatg aacgagaagg gaactgaggc tgcagctgcc
     1201 tctggcctcc tgtcccagcc cccagccctg aacatgacat cagccccaca ggcccactat
     1261 aacaggccct tcctgcttct gctctgggag gtgaccaccc agagtctgct cttcttgggg
     1321 aaagtggtca acccagctgc tgggtaattg tggtggggag gccacaggaa ggcccaacct
     1381 gcacggcagg acccccctgc atggcaggac ccctgtgctt cagttctaat aaatctgaat
     1441 ttggctgtgc aaagtcccct g
//
