LOCUS       NM_001160326             782 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus stress-associated endoplasmic reticulum protein family
            member 2 (Serp2), transcript variant 1, mRNA.
ACCESSION   NM_001160326 XM_894566 XM_987594
VERSION     NM_001160326.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU057067.1 and CF728547.1.
            
            On or before Aug 23, 2009 this sequence version replaced
            XM_987594.1, XM_894566.3.
            
            Transcript Variant: This variant (1) represents the protein coding
            transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU057067.1, BQ177727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-645               BU057067.1         1-645
            646-782             CF728547.1         405-541
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 40.44 cM"
     gene            1..782
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /note="stress-associated endoplasmic reticulum protein
                     family member 2"
                     /db_xref="GeneID:72661"
                     /db_xref="MGI:MGI:1919911"
     exon            1..257
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..371
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     stress-associated endoplasmic reticulum protein 2;
                     ribosome-associated membrane protein RAMP4-2"
                     /codon_start=1
                     /product="stress-associated endoplasmic reticulum protein
                     2 isoform 1"
                     /protein_id="NP_001153798.1"
                     /db_xref="CCDS:CCDS49546.1"
                     /db_xref="GeneID:72661"
                     /db_xref="MGI:MGI:1919911"
                     /translation="MVAKQRIRMANEKHSKNITQRGNVAKTLRPQEEKYPVGPWLLAL
                     FVFVVCGSAIFQIIQSIRMGM"
     exon            258..330
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            331..765
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      741..746
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      765
                     /gene="Serp2"
                     /gene_synonym="2810032E02Rik"
                     /note="major polyA site"
ORIGIN      
        1 cgcgctggcc tctctctgga gccggctggc tggggctccg ggagcggggt gcgcggggct
       61 cggccgtgcc ttgccacctg cagcgcccgg gcaagccgcg gggcgctgcg gctacggctc
      121 accccggcca tcgttgcagg tgggagtcga gagcatcccc aagcgcccaa gccatggtgg
      181 ccaaacagcg gatccggatg gctaacgaga agcacagcaa aaacatcacc cagaggggaa
      241 acgtagccaa aaccctgagg ccacaagaag agaaatatcc tgttgggcca tggctgctgg
      301 ccctgtttgt ttttgttgtc tgtggctcag ctatcttcca gatcatacag agcataagga
      361 tgggcatgtg agagggccag gaagttgtat gcggatgccc tcctgctggc aggtgaagga
      421 ccactgaggc cttcagcggg tcttatagga agcaaacaag ccatgggtga tagaaaggag
      481 gccccctgtt tcctcccacg ccatggtgga ggtcagacca aattgccttc tcacaagaca
      541 tctccgtgca tctgtgtcct ccagcggaaa ggactctgct cttctgttgg ctgattggaa
      601 gtcacgtggg gggccgggcg gcggcgctgg ctggctggct ggttccccgg gtttcactgt
      661 ggtgtgcatg tggccctctg agcgaccacc cctttacatc ctgccaatca atctcttctg
      721 tgtcaggaat tggttttaca aataaatgtc ttcattcaac cttaaaaaaa aaaaaaaaaa
      781 aa
//
