LOCUS       NM_012032               2251 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus serine incorporator 3 (Serinc3), transcript variant 1,
            mRNA.
ACCESSION   NM_012032
VERSION     NM_012032.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2251)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2251)
  AUTHORS   Timilsina,U., Umthong,S., Lynch,B., Stablewski,A. and Stavrou,S.
  TITLE     SERINC5 Potently Restricts Retrovirus Infection In Vivo
  JOURNAL   mBio 11 (4), e00588-20 (2020)
   PUBMED   32665269
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2251)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2251)
  AUTHORS   Bossolasco,M., Veillette,F., Bertrand,R. and Mes-Masson,A.M.
  TITLE     Human TDE1, a TDE1/TMS family member, inhibits apoptosis in vitro
            and stimulates in vivo tumorigenesis
  JOURNAL   Oncogene 25 (33), 4549-4558 (2006)
   PUBMED   16547497
  REMARK    GeneRIF: TDE1 inhibits apoptosis and stimulates tumorigenesis
REFERENCE   5  (bases 1 to 2251)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2251)
  AUTHORS   Grossman,T.R., Luque,J.M. and Nelson,N.
  TITLE     Identification of a ubiquitous family of membrane proteins and
            their expression in mouse brain
  JOURNAL   J Exp Biol 203 (Pt 3), 447-457 (2000)
   PUBMED   10637174
REFERENCE   7  (bases 1 to 2251)
  AUTHORS   Bossolasco,M., Lebel,M., Lemieux,N. and Mes-Masson,A.M.
  TITLE     The human TDE gene homologue: localization to 20q13.1-13.3 and
            variable expression in human tumor cell lines and tissue
  JOURNAL   Mol Carcinog 26 (3), 189-200 (1999)
   PUBMED   10559794
REFERENCE   8  (bases 1 to 2251)
  AUTHORS   Takenaka,M., Imai,E., Kaneko,T., Ito,T., Moriyama,T., Yamauchi,A.,
            Hori,M., Kawamoto,S. and Okubo,K.
  TITLE     Isolation of genes identified in mouse renal proximal tubule by
            comparing different gene expression profiles
  JOURNAL   Kidney Int 53 (3), 562-572 (1998)
   PUBMED   9507200
REFERENCE   9  (bases 1 to 2251)
  AUTHORS   Kerr,S.M., Vambrie,S., McKay,S.J. and Cooke,H.J.
  TITLE     Analysis of cDNA sequences from mouse testis
  JOURNAL   Mamm Genome 5 (9), 557-565 (1994)
   PUBMED   8000140
REFERENCE   10 (bases 1 to 2251)
  AUTHORS   Lebel,M. and Mes-Masson,A.M.
  TITLE     Sequence analysis of a novel cDNA which is overexpressed in
            testicular tumors from polyomavirus large T-antigen transgenic mice
  JOURNAL   DNA Seq 5 (1), 31-39 (1994)
   PUBMED   7894057
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591490.12 and AL591488.7.
            
            On Sep 30, 2022 this sequence version replaced NM_012032.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK164807.1, AK155921.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                AL591490.12        19867-19957         c
            92-253              AL591490.12        14035-14196         c
            254-447             AL591490.12        11680-11873         c
            448-527             AL591490.12        9304-9383           c
            528-665             AL591490.12        6975-7112           c
            666-835             AL591490.12        5795-5964           c
            836-926             AL591490.12        3996-4086           c
            927-1107            AL591490.12        2741-2921           c
            1108-1332           AL591490.12        1122-1346           c
            1333-2251           AL591488.7         189945-190863       c
FEATURES             Location/Qualifiers
     source          1..2251
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 84.38 cM"
     gene            1..2251
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="serine incorporator 3"
                     /db_xref="GeneID:26943"
                     /db_xref="MGI:MGI:1349457"
     exon            1..91
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            92..253
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            254..447
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            448..527
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            528..665
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            666..835
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            836..926
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1107
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1332
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..2251
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2116..2121
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="hexamer: ATTAAA"
     regulatory      2121..2126
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="hexamer: AATGAA"
     polyA_site      2138
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="major polyA site"
     polyA_site      2144
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="major polyA site"
     regulatory      2231..2236
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="hexamer: ATTAAA"
     polyA_site      2251
                     /gene="Serinc3"
                     /gene_synonym="AIGP1; DIFF33; Tde1; TMS-1"
                     /note="major polyA site"
ORIGIN      
        1 agtcagcagt taggatccgc tcggagcggt cggtctcggc cccggcgtca ccatgggggc
       61 cgtcctcggc gtcttctccc tcgccagctg ggtcccgtgc ctctgtagtg gtgcatcatg
      121 tctgctgtgc agttgctgtc ccatcagtaa gaattccact gtaactcggc tcatctacgc
      181 ttttatcctc ttccttggca ctattgtgtc ttgcatcatg atgacagaag gcatacaaac
      241 tcaactgaag aagattcctg gattctgtga aggaggattt caaatcaaga tggttgatac
      301 aaaggcagag aaagattgtg acgtgctggt cggttttaaa gctgtgtatc ggatcaactt
      361 tgctgtggcc atctttttct ttgccttctt tttgctcatg ttaaaagtta aaacaagtaa
      421 agatcccaga gcagcagtgc acaacgggtt ttggttcttc aaaatcgctg ccattattgg
      481 tatcatgatt ggatctttct acatccctgg gggcagtttt actgaagtct ggtttgttgc
      541 tggaatgttg ggggcctctt tcttcattat catccagctg gtgctcttgg tagacatggc
      601 tcactcttgg aatgaattat gggtaaatcg aatggaggaa ggaaacccaa ggctctggta
      661 tgctgccttg ctgtccttta caagcctctt ttacatcctc tccatcgtct ttgctgcgct
      721 gctctacgtc ttctacacca agcctgacga ctgcacagaa aacaaggtct tcatcagcct
      781 caacctgatt ttttgtgttg cagtttctat tgtgtccatc ctccctaaag ttcaggaaca
      841 tcagcctcgc tctggcctcc tgcagtcctc catcatcact ctgtacaccc tttacctcac
      901 gtggtcagcc atgaccaatg aacctgagcg gtcctgcaat ccctccctta tgagcatcat
      961 cacacactta acttcaccaa ctgtgtctcc tgcaaattca actactcttg ctcctgccta
     1021 tgctccgccg tcacagagtg ggcactttat gaatttggat gatatttggg gactgattat
     1081 ctttgttttc tgccttatat attctagctt ccgtacttcg agcaacagcc aagttaacaa
     1141 gctgaccctc tctgggagtg acagtgttat ccttggtgat accaccaatg gagccaatga
     1201 tgaagaggat ggacagccac ggagggctgt agacaatgag aaggaggggg tgcagtatag
     1261 ctactccttt ttccacttga tgctctgctg tgcctccttg tacatcatga tgaccataac
     1321 cagctggtac agccctgatg ccaaattcca gaaggtatcc agcaagtggc tagctgtgtg
     1381 gttcaaaatg ggctccagct ggttgtgcct cctcctttac ctctggactc ttgtggctcc
     1441 cctggtcctc acaggtcggg acttcagctg agctcagtgt gtcaaggaca ctgataaagc
     1501 tgaccagagt ctccttttct gaaaatgcat atccattttg cgtttcatca acgagactat
     1561 taagtgaacg ctttgcagat ttggctgtat tcaggtttat atcaaaaggc aagattgagt
     1621 aatgcttgat gcagaatctg agctttcata tatatatata tatatatata tatatacaca
     1681 cacacacaca cacatatata tgtttatttg taaggctata gcacaaaggg aacatttttg
     1741 tgttttaaca tgaactacag ctgtgctgtg aagagaattc tttataaaga cctgtagatt
     1801 cctacaactt tggtttaagt tttaagttag aagattgttg gatatttaag gctattttta
     1861 atttctatta cagtctcctt aaaaaccaaa aaggaatgca ttaatccaca tttcccttct
     1921 tcagaggtgt agtgtcctgg ctcttggcaa ggaattatgt atttaggtca gtccccagaa
     1981 atgcagctgc tcatacagct gagagaaggc tattattgag ttcctttact tactttttat
     2041 actacactga tgctgcttga tagaagtctg tggctttgtc agatatgtca cccaagtaaa
     2101 tgctttgtag atctgattaa aatgaaaagc tcacttgaga aacactgcag agttatgtaa
     2161 tgatcttgtt gtgagtgtgt gaaagtcaaa ggcatgtcag tttattacat ttgcaacata
     2221 aaagtactta attaaaatag atatttagtt t
//
