LOCUS       NM_011353                553 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus small EDRK-rich factor 1 (Serf1), mRNA.
ACCESSION   NM_011353
VERSION     NM_011353.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 553)
  AUTHORS   Stroo,E., Janssen,L., Sin,O., Hogewerf,W., Koster,M., Harkema,L.,
            Youssef,S.A., Beschorner,N., Wolters,A.H., Bakker,B., Becker,L.,
            Garrett,L., Marschall,S., Hoelter,S.M., Wurst,W., Fuchs,H.,
            Gailus-Durner,V., Hrabe de Angelis,M., Thathiah,A., Foijer,F., van
            de Sluis,B., van Deursen,J., Jucker,M., de Bruin,A. and Nollen,E.A.
  TITLE     Deletion of SERF2 in mice delays embryonic development and alters
            amyloid deposit structure in the brain
  JOURNAL   Life Sci Alliance 6 (7), e202201730 (2023)
   PUBMED   37130781
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 553)
  AUTHORS   Scharf,J.M., Endrizzi,M.G., Wetter,A., Huang,S., Thompson,T.G.,
            Zerres,K., Dietrich,W.F., Wirth,B. and Kunkel,L.M.
  TITLE     Identification of a candidate modifying gene for spinal muscular
            atrophy by comparative genomics
  JOURNAL   Nat Genet 20 (1), 83-86 (1998)
   PUBMED   9731538
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT030167.8.
            
            On Jan 10, 2022 this sequence version replaced NM_011353.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CN839880.1, AF073517.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               CT030167.8         87913-88087
            176-284             CT030167.8         88881-88989
            285-553             CT030167.8         93823-94091
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 52.98 cM"
     gene            1..553
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /note="small EDRK-rich factor 1"
                     /db_xref="GeneID:20365"
                     /db_xref="MGI:MGI:1337114"
     exon            1..175
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /inference="alignment:Splign:2.1.0"
     CDS             169..357
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /note="protein 4F5; modifier of spinal muscular atrophy
                     candidate 1"
                     /codon_start=1
                     /product="small EDRK-rich factor 1"
                     /protein_id="NP_035483.1"
                     /db_xref="CCDS:CCDS36765.1"
                     /db_xref="GeneID:20365"
                     /db_xref="MGI:MGI:1337114"
                     /translation="MARGNQREIARQKNMKKTQEISKGKRKEDSLTASQRKQRDSEIM
                     QQKQKIANEKKSMQTTEK"
     exon            176..284
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /inference="alignment:Splign:2.1.0"
     exon            285..553
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      529..534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /note="hexamer: AATAAA"
     polyA_site      553
                     /gene="Serf1"
                     /gene_synonym="4F5; m4F5; Msmac1"
                     /note="major polyA site"
ORIGIN      
        1 gttgtgggtc ggtgggcggg gcggctggct ggccgagcga ggcgtcgcca catcgagggc
       61 ccttgtgggg ctcagccttc ttcagcgccc ggcggcaacg gctgagcgtg caaagccgcc
      121 gtttgcttct ccaggtcgct gtcttccagt ctccggccgg tggacagcat ggcccgtgga
      181 aatcaaagag aaattgcccg acagaaaaac atgaaaaaga cccaggaaat tagcaaaggg
      241 aaaagaaaag aggacagctt gactgcctct cagagaaagc agagggattc agagatcatg
      301 caacaaaagc agaagatagc caatgagaag aaatctatgc agacaacaga aaaatgatga
      361 ctggcttttt ggaaaacctg ggtgctattg ccagtgggtg catcatacgc tctaagatta
      421 aaatttcaca gtgactaatc attatatgtg ttataacttg tccttataaa actattttaa
      481 actttactct tcagcctatc ttaatgtgat gttttaagac catcaaaaaa taaagtactg
      541 accttgcatg taa
//
