LOCUS       NM_001368785            6022 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus septin 3 (Septin3), transcript variant 11, mRNA.
ACCESSION   NM_001368785
VERSION     NM_001368785.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6022)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6022)
  AUTHORS   Toth,V., Vadaszi,H., Ravasz,L., Mittli,D., Matyas,D., Molnar,T.,
            Micsonai,A., Szaniszlo,T., Lorincz,P., Kovacs,R.A., Juhasz,T.,
            Beke-Somfai,T., Juhasz,G., Gyorffy,B.A., Kekesi,K.A. and Kardos,J.
  TITLE     Neuronal-specific septin-3 binds Atg8/LC3B, accumulates and
            localizes to autophagosomes during induced autophagy
  JOURNAL   Cell Mol Life Sci 79 (9), 471 (2022)
   PUBMED   35932293
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6022)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6022)
  AUTHORS   Yoshida,A., Yamamoto,N., Kinoshita,M., Hiroi,N., Hiramoto,T.,
            Kang,G., Trimble,W.S., Tanigaki,K., Nakagawa,T. and Ito,J.
  TITLE     Localization of septin proteins in the mouse cochlea
  JOURNAL   Hear Res 289 (1-2), 40-51 (2012)
   PUBMED   22575789
REFERENCE   5  (bases 1 to 6022)
  AUTHORS   Shinoda,T., Ito,H., Sudo,K., Iwamoto,I., Morishita,R. and Nagata,K.
  TITLE     Septin 14 is involved in cortical neuronal migration via
            interaction with Septin 4
  JOURNAL   Mol Biol Cell 21 (8), 1324-1334 (2010)
   PUBMED   20181826
REFERENCE   6  (bases 1 to 6022)
  AUTHORS   Fujishima,K., Kiyonari,H., Kurisu,J., Hirano,T. and Kengaku,M.
  TITLE     Targeted disruption of Sept3, a heteromeric assembly partner of
            Sept5 and Sept7 in axons, has no effect on developing CNS neurons
  JOURNAL   J Neurochem 102 (1), 77-92 (2007)
   PUBMED   17564677
  REMARK    GeneRIF: Sept3 is dispensable for normal neuronal development
REFERENCE   7  (bases 1 to 6022)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   8  (bases 1 to 6022)
  AUTHORS   Hentges,K.E., Yarlagadda,S.P. and Justice,M.J.
  TITLE     Tnfrsf13c (Baffr) is mis-expressed in tumors with murine leukemia
            virus insertions at Lvis22
  JOURNAL   Genomics 80 (2), 204-212 (2002)
   PUBMED   12160734
REFERENCE   9  (bases 1 to 6022)
  AUTHORS   Xiong,J.W., Leahy,A. and Stuhlmann,H.
  TITLE     Retroviral promoter-trap insertion into a novel mammalian septin
            gene expressed during mouse neuronal development
  JOURNAL   Mech Dev 86 (1-2), 183-191 (1999)
   PUBMED   10446280
REFERENCE   10 (bases 1 to 6022)
  AUTHORS   Xiong,J.W., Battaglino,R., Leahy,A. and Stuhlmann,H.
  TITLE     Large-scale screening for developmental genes in embryonic stem
            cells and embryoid bodies using retroviral entrapment vectors
  JOURNAL   Dev Dyn 212 (2), 181-197 (1998)
   PUBMED   9626494
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104325.28.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR5189685.140345.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-266               AC104325.28        117718-117983
            267-1699            AC104325.28        120349-121781
            1700-1891           AC104325.28        128331-128522
            1892-2020           AC104325.28        131975-132103
            2021-2102           AC104325.28        132593-132674
            2103-2240           AC104325.28        133288-133425
            2241-2358           AC104325.28        134703-134820
            2359-2454           AC104325.28        135353-135448
            2455-2554           AC104325.28        138111-138210
            2555-2606           AC104325.28        139320-139371
            2607-2700           AC104325.28        139654-139747
            2701-6022           AC104325.28        140169-143490
FEATURES             Location/Qualifiers
     source          1..6022
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.56 cM"
     gene            1..6022
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /note="septin 3"
                     /db_xref="GeneID:24050"
                     /db_xref="MGI:MGI:1345148"
     exon            1..266
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            267..1699
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..2754
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /note="isoform 11 is encoded by transcript variant 11;
                     neuronal-specific septin-3"
                     /codon_start=1
                     /product="neuronal-specific septin-3 isoform 11"
                     /protein_id="NP_001355714.1"
                     /db_xref="CCDS:CCDS88812.1"
                     /db_xref="GeneID:24050"
                     /db_xref="MGI:MGI:1345148"
                     /translation="MNHAFAPAPPEMQPHRAPGPRTSFSHSHMLGHHTHQKLTADVSP
                     LIPVIKKTGRLDAFPQSSVLENSKQPSIRSRACSMSQQGTATGSLSSMPPNSFMPRKL
                     SSISLTIHQNVQTRPLDASLSHWEELPSLHKEAVTHREGRLSASSLPLMAHVPQVRTS
                     SEGHGNPELTKASRTPTGNKPLVSSCLTLPFQAQFIQSSSSLPGPGPMGQVPSRASPG
                     RGKCRPRGIPRSRAYLQRATSAANVSVVSTKLDKARHIGTVALHRPELAINMPTLNQS
                     RLVRSAELPVLDARMDLATNLPVVSKSGKVTDSIAAGTARDLARAVTTKSGQVPNLVT
                     AASDKQESVKLLTTGNSNVALPTSDEAKQGITRLDTVKALARATVGRPDTMTDSPALE
                     TSRLGTAMDSVVLVCPDPASSETKPHTVNNGTIRDTVTYATSPQKPSRSTDPAQDHGA
                     VGASTDSLKEPTSLDLAPEPKGLPEARTDAAMSELVPEPRPKPAVPMKPVSINSNLLG
                     YIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEK
                     IPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKE
                     EVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTL
                     EEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQV
                     NGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLN
                     DNGGLPPNKKLCASLKRSGEGFNL"
     exon            1700..1891
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..2020
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2021..2102
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2240
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2241..2358
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2454
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..2554
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2555..2606
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2700
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     exon            2701..6022
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5997..6002
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /note="hexamer: ACTAAA"
     polyA_site      6022
                     /gene="Septin3"
                     /gene_synonym="3110018K01Rik; B530002E20Rik; Gm46500;
                     Sep3; Sept3"
                     /note="major polyA site"
ORIGIN      
        1 agaagctcac tcgccaaggc gagcagctca caggaaagca ggccagagcc cccagtgttg
       61 tggggtatgg cagaaaggaa gtggcaagat gatgggtcga ggacatgcca agagaacgtt
      121 gggcttggct cctggctcag agtgagtgtt tagggcacgt ctgtggcctg cactctgtgg
      181 ctgagatgct gtgcccatct gcttacgggc ctggctttgg cagaagactc tgagtttctc
      241 cagcctggct cagtccctgg cacagaggaa agctggacag cctggatgaa ccacgccttc
      301 gcacctgctc ctccggagat gcagccacac agggctccag gccccagaac atctttctct
      361 cacagccaca tgctggggca ccacacccac caaaagctca ctgcagatgt gtcccccctc
      421 atccctgtca tcaagaagac tgggcgtttg gatgccttcc cccaaagcag tgtcctagag
      481 aattccaaac agccaagcat tagatccagg gcctgtagta tgtcccaaca gggcactgcc
      541 acggggtccc tgagttccat gcctcccaat agctttatgc ccaggaaact cagctctatt
      601 tccttaacaa tacaccagaa tgtccaaacg cggcccttag atgcctcact ttctcattgg
      661 gaagaattgc ccagtttgca caaggaggct gtcacccaca gagaagggag gctgtctgct
      721 tcaagtttgc cactcatggc tcatgtgcca caggtcagga cctcctctga aggccatggg
      781 aacccagaac ttaccaaagc cagcagaaca cccacaggga ataaacctct ggtgtcttca
      841 tgcctgactt tacctttcca agctcagttc attcagagtt cgtcaagcct cccggggcca
      901 ggtcccatgg gacaagtccc ttccagagcc tctccaggaa gaggcaagtg caggcccagg
      961 ggtattccca gatcccgagc atacctccaa agggctacct cggctgcaaa tgtgtctgtt
     1021 gtgagcacaa aactagataa agccagacat ataggcacag tggctctcca cagaccggaa
     1081 ttggctatca atatgcctac actaaaccag tccagactgg tcagaagcgc agagcttcct
     1141 gttctggatg ccaggatgga cctggccacc aacttacctg tagtatccaa gtcaggaaaa
     1201 gtgacagact caattgcagc aggcacagcc agggatttag ctagagcagt gacaaccaag
     1261 tcaggccagg ttccgaattt ggtaactgca gcatcagaca agcaggaaag tgtcaagctt
     1321 ttgaccacgg ggaactcaaa cgtggctttg ccaacatcgg atgaggccaa gcagggcata
     1381 accaggttgg acacagtcaa agctttggcc agagccaccg taggcaggcc ggacacaatg
     1441 acagattctc ctgcactgga gacaagcaga ctaggtacag ccatggattc agttgtgctg
     1501 gtctgcccag acccagccag tagtgagacc aagccacaca ctgtcaacaa tgggactatc
     1561 agagacacgg ttacctatgc tacctctcct caaaagccga gcagaagcac agacccagcc
     1621 caggaccatg gagctgtggg tgcttccaca gacagcctca aggaacccac ctcgctggac
     1681 ctggccccag aacccaaagg gctcccagag gctaggacgg acgcagccat gtctgagctg
     1741 gtacctgagc ccaggcctaa gccggcggtg cccatgaagc cggtcagcat caactccaac
     1801 ctgctaggct acattggcat tgacaccatt atcgagcaga tgcgcaagaa gaccatgaag
     1861 actggctttg acttcaacat catggtcgtt ggccagagtg gactgggcaa gtcaacactg
     1921 gtcaacaccc tcttcaagtc ccaagtgagc cgaaaggcct ccagctggaa ccgggaggag
     1981 aagatcccca agacagtgga gatcaaagcg attgggcatg tgatagagga aggtggtgtc
     2041 aaaatgaagc tgacagtcat cgacacacca ggctttggag accagatcaa caatgaaaac
     2101 tgctgggagc ccattgagaa atacatcaac gaacagtacg aaaagttcct gaaggaggag
     2161 gtgaacattg ccaggaagaa acgcatccct gacacccgtg tccactgctg cctctacttc
     2221 atctccccga caggacactc cttacgacca ctggatcttg agttcatgaa acatctcagc
     2281 aaagtggtga acatcattcc tgtcattgcc aaggctgata ccatgaccct ggaggagaag
     2341 tcggaattca agcagagggt tcgcaaagaa cttgaagtaa acggcattga attctaccct
     2401 cagaaggaat ttgatgagga tttggaggac aagacagaga atgacaaaat ccggcaggag
     2461 agcatgccct tcgccgtggt ggggagtgac aaggagtacc aagtgaacgg caagagggtc
     2521 ctcgggagga aaacaccctg ggggatcatc gaagtggaaa acctcaacca ctgtgagttt
     2581 gccctgctcc gagacttcgt catcaggact cacctccagg acctcaaaga agtaacacac
     2641 aacatccact atgagactta cagggccaag aggctcaatg acaatggagg cctccctccg
     2701 aacaaaaagc tgtgcgcctc actcaagagg tctggggaag gttttaattt ataatgctgg
     2761 gagcaggtga gccacaggca actctttctt acttctgacc cacccacaaa ctggggctgc
     2821 aagtattctt catggactgg tggctgagct agcctgtggt gggctgtggg agctcagaac
     2881 aacttttcac tgtaagttga ggtaatctgg aggaaggcta ggacttcttg gggaaacaga
     2941 agattcgtgg ggagcagaga agaaagctga ggggctcctg cagaattggt gtctgaaaat
     3001 ggagctccac ccttgtgtct atgttggggt cactgtcaaa cagcggatca tcaccgctgc
     3061 aaaccactgc tttctgtgcc cgccttccct gtatttccag gctggttggt tgcttcctcg
     3121 tcctgatttc tcttctccct ccccagcgtc ctttgcctcc tttcttcata tatattcatg
     3181 cattcacccc atttcctgcc tgtctctgac cttttatctc cttttagagt catctatgtt
     3241 agcttccttt ctatatttag aaatcatgcc cagactttct aaattgactt tctattaccc
     3301 taagatagaa tcacagctag gggctgaaga gatggctctg tgcttcgggg gaccttttgc
     3361 tcttgcagag gacccaggtt cagttcccag caccttcttg gtagcttaca gttatctgtg
     3421 actccagttc cagaggacct gacaccctct tttagcctct atgagcatgg tgtacataca
     3481 tacacataga caagcactca tacgcataag ataaaaaaaa aaaaaaccct taaaagaata
     3541 agatcctaag taaaagcatg gggcagggca tgccgagatt gcaagagaat tcagttatag
     3601 agaagatgac taggaaagcc agtttctgca gctgaccact gaaatttgct ctgacttggg
     3661 aatagcctgg ggaaatggga gaatttggta gcttgggctg ctctgggtgt tctgttcaag
     3721 aagcacatct attgggcaaa tgaggcaaac tttaggtgga ggaaattata ttcacaaact
     3781 aattctgaag aatcggaaaa aatatacaga gtttcttagg cggctggact tgtgagacaa
     3841 actaacacag tttcccgttt tctagcagcc ttctgtccat gttaagctgg cttctctgtg
     3901 gctttgtttc ttacaaaccc aactcactct ttctctgttc tcatttgtct gtctgtcttt
     3961 ctcggcttct cccctccctg cattctctca ccatccaatc ctgtagatgt tcccaggaat
     4021 acccacagcc atacatttag ccttctcttg ccttctcagg agccttgtat ttattaatgc
     4081 atactttaac tgctccttgc acattcaagt tttttttttt tccctacagt ttctaaggct
     4141 gctttaagga aagccattta gccataggaa agggaagata ccacaaaatt ctgtttagaa
     4201 ctgatctatc cactatgcca cctcccggtc cagcctgggt gtagaactgg tcttcactga
     4261 cttcagccct ttattaccca gtcactagga aaacaaacac acagacaaac aaaaaacaaa
     4321 aagagatgga agacccacaa ttcagtggac caagcagaag tggtcctaat cctatggtct
     4381 tagcctttcc tggagactgc tctgtctcta gtcctcatct ataacgtcac taaagagtgg
     4441 ccagctgtca ggctagagtg gtagcaacat agagctcgct gacagctcta gtgagctgcc
     4501 ctgtatggtg acatgggatt gggcacctag ggccagcaag ggataagaat ggtgggtgtt
     4561 ggagagtcta agtaggagaa tgctgcctgt ctccactaag ctgtggtctc actctccctg
     4621 gagaagctgt tttatgtgtc tgctgccggc tgccggtctc cacaccctca accgttctca
     4681 actccccctg cagggagaag gcctcctggg cactgtcctt ccacctgtac cagccacccc
     4741 ctgccccact gctgaatgaa ggccatttca agtgctgctt ctccctcatc cctcccagct
     4801 gttattgctg cagggccacg ccccttttag cgctgtgctt gtctagccca ccagcacagc
     4861 ccctctcagc cctcagtagg tgggaggggc tagctgcggc tttaggacag ttgcttcctc
     4921 tgtttagcca aactactcct ctcctcccaa tggaatggag ttcctgccag caccaccctg
     4981 ctccatcatc tgtgtcagca gcaccccagt ccttgtgtag ggaggaggaa ctcatgggaa
     5041 gctgctcctg cccttgcaag cgcataccag cgacttgtaa ctgtctccaa gggaaccggc
     5101 attgctctct agccattcat tctgcatgag tactttcttg gctaccttaa ccggtcaaga
     5161 aagcaacttt cctgcttgtc agagtcactg aggtcagccg tgtgagcccc tgtgtgggac
     5221 aagggtgtct ccttcattgc ttaaaggtat tttataaggg tgattcatta tacatggtgg
     5281 ggagccagag gctagtgtca cttaaaaaaa aaaatcacca ctggtggctg gcccagtgag
     5341 tatgtgtgta gacaacctgt ttaccccaaa atatggccat ctgggaagtg ggttttgctg
     5401 aaaagaggtt gctggagttg acttaattat ccccaaactt taaaagaaag ggaatttaac
     5461 acacatatgg actaccccaa acccaccagc tatacactct aggaagaaaa atagcaccct
     5521 tttatacatt tagcaataag agggatctct tcccacctcc cctgactatt cctactccca
     5581 tcccccaccc tgttaatgtg agcaatgcat tagcctgacc acaggtggtc gctataggct
     5641 aatggaaaat acccaaatgg agggcaaagc ccccatcaga tgcatgaatg tttgcgaacg
     5701 aacggctgcc actgccccat acactgtgtc tttctagaac cctccctcag ccaccccacc
     5761 tgccatctcc acctggacac aacttgctca aaggctggtg acttgtgggc cattcatcta
     5821 caagtcctga aggaacaaga ggcccaagcc tcggggatgc aagaatggcc cattttaaaa
     5881 acgttgttag tcccagccga cgtttttggt gatattccag tttagtttcc caattgaaaa
     5941 caagccaaac agacactcag actggtcatg tagatgttgc tagcctctgt tgtacaacta
     6001 aacattactg tttgaacaat aa
//
