LOCUS       NM_001413627            4555 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus sema domain, immunoglobulin domain (Ig), transmembrane
            domain (TM) and short cytoplasmic domain, (semaphorin) 4G (Sema4g),
            transcript variant 1, mRNA.
ACCESSION   NM_001413627 XM_036161602
VERSION     NM_001413627.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4555)
  AUTHORS   Bessa,P., Newman,A.G., Yan,K., Schaub,T., Dannenberg,R., Lajko,D.,
            Eilenberger,J., Brunet,T., Textoris-Taube,K., Kemmler,E., Deng,P.,
            Banerjee,P., Ravindran,E., Preissner,R., Rosario,M. and
            Tarabykin,V.
  TITLE     Semaphorin heterodimerization in cis regulates membrane targeting
            and neocortical wiring
  JOURNAL   Nat Commun 15 (1), 7059 (2024)
   PUBMED   39152101
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4555)
  AUTHORS   Yan,K., Bormuth,I., Bormuth,O., Tutukova,S., Renner,A., Bessa,P.,
            Schaub,T., Rosario,M. and Tarabykin,V.
  TITLE     TrkB-dependent EphrinA reverse signaling regulates callosal axon
            fasciculate growth downstream of Neurod2/6
  JOURNAL   Cereb Cortex 33 (5), 1752-1767 (2023)
   PUBMED   35462405
REFERENCE   3  (bases 1 to 4555)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4555)
  AUTHORS   Sar Shalom,H., Goldner,R., Golan-Vaishenker,Y. and Yaron,A.
  TITLE     Balance between BDNF and Semaphorins gates the innervation of the
            mammary gland
  JOURNAL   Elife 8, e41162 (2019)
   PUBMED   30628891
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4555)
  AUTHORS   Memic,F., Knoflach,V., Morarach,K., Sadler,R., Laranjeira,C.,
            Hjerling-Leffler,J., Sundstrom,E., Pachnis,V. and Marklund,U.
  TITLE     Transcription and Signaling Regulators in Developing Neuronal
            Subtypes of Mouse and Human Enteric Nervous System
  JOURNAL   Gastroenterology 154 (3), 624-636 (2018)
   PUBMED   29031500
REFERENCE   6  (bases 1 to 4555)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   7  (bases 1 to 4555)
  AUTHORS   Lillesaar,C. and Fried,K.
  TITLE     Neurites from trigeminal ganglion explants grown in vitro are
            repelled or attracted by tooth-related tissues depending on
            developmental stage
  JOURNAL   Neuroscience 125 (1), 149-161 (2004)
   PUBMED   15051154
REFERENCE   8  (bases 1 to 4555)
  AUTHORS   Dionne,M.S., Brunet,L.J., Eimon,P.M. and Harland,R.M.
  TITLE     Noggin is required for correct guidance of dorsal root ganglion
            axons
  JOURNAL   Dev Biol 251 (2), 283-293 (2002)
   PUBMED   12435358
REFERENCE   9  (bases 1 to 4555)
  AUTHORS   Lemon,W.J., Bernert,H., Sun,H., Wang,Y. and You,M.
  TITLE     Identification of candidate lung cancer susceptibility genes in
            mouse using oligonucleotide arrays
  JOURNAL   J Med Genet 39 (9), 644-655 (2002)
   PUBMED   12205107
REFERENCE   10 (bases 1 to 4555)
  AUTHORS   Li,H., Wu,D.K. and Sullivan,S.L.
  TITLE     Characterization and expression of sema4g, a novel member of the
            semaphorin gene family
  JOURNAL   Mech Dev 87 (1-2), 169-173 (1999)
   PUBMED   10495281
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132957.3.
            
            On Nov 3, 2022 this sequence version replaced XM_036161602.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.33731.1,
                                           SRR9219381.213055.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                AC132957.3         96553-96630
            79-264              AC132957.3         98446-98631
            265-765             AC132957.3         99411-99911
            766-914             AC132957.3         100007-100155
            915-977             AC132957.3         100393-100455
            978-1076            AC132957.3         103742-103840
            1077-1170           AC132957.3         103953-104046
            1171-1284           AC132957.3         104193-104306
            1285-1448           AC132957.3         104565-104728
            1449-1618           AC132957.3         104802-104971
            1619-1763           AC132957.3         105237-105381
            1764-1986           AC132957.3         105505-105727
            1987-2102           AC132957.3         105944-106059
            2103-2263           AC132957.3         106151-106311
            2264-2325           AC132957.3         106452-106513
            2326-4555           AC132957.3         108441-110670
FEATURES             Location/Qualifiers
     source          1..4555
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 38.16 cM"
     gene            1..4555
                     /gene="Sema4g"
                     /note="sema domain, immunoglobulin domain (Ig),
                     transmembrane domain (TM) and short cytoplasmic domain,
                     (semaphorin) 4G"
                     /db_xref="GeneID:26456"
                     /db_xref="MGI:MGI:1347047"
     exon            1..78
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            79..264
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            265..765
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     CDS             642..3155
                     /gene="Sema4g"
                     /note="semaphorin-4G"
                     /codon_start=1
                     /product="semaphorin-4G precursor"
                     /protein_id="NP_001400556.1"
                     /db_xref="GeneID:26456"
                     /db_xref="MGI:MGI:1347047"
                     /translation="MWGRLWPLLFSFLTVTAVPGPSLRRPSRELDATPRLTISYEELS
                     QIRHFKGQTQNYSTLLLEEASERLLVGARGALFSLSARDIRDRTHKEIHWEASPEMQS
                     KCHQKGKNNQTECFNHVRFLQRLNATHFYACGTHAFQPLCAAIDAETFILPTSFEEGK
                     EKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEF
                     VFSVLVRESKTSAVGDDDKIYFFFMEREEGSSSFTQSRSSHRVARVARVCKGDLGGKK
                     ILQKKWTSFLKARLICHIPQYETLRGVCSLNADTSSHTHFYAVFTLTTQWKTLEASAI
                     CRYDLAEIQAVFTGPFMEYQDGARRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLP
                     SLVLDFVKLHPLMARPVVPTRGRPLLLKRNVRYTHLTGTHVSTPAGPTYDLLFLGTAD
                     GWIHKAVVLGSGMHIIEEIQVFREPQSVDNLVISPMQHSLYVGAASGVLQFPLSSCSR
                     YQSCYDCILARDPYCGWDSSIHACMVATTVANRTELIQDIERGNRGCEGSRDAGPPPP
                     LKTRSVLRGDDVLLPCDQPSNLARALWLLNGSKSLSDGQDGYRVGVDGLLVTDTQLEH
                     SGNYGCYAEENGLRMLLASYSLTVRPATPAPAPQAPATPGAQLAHDMRMFYVVAIAIL
                     GGLCLILASSLLYVACLKGGRRGRRRKYSLGRAGRAGGSAVQLQTVSGQCPGEEDEGD
                     DGEGTGGLESGCLQIIPGEGAPAPPPPPPPPPPAELTNGLVALPSRLRRMNGNSYVLL
                     RQSNNGVPAGPCSFAEELSRILEKRKHTQLVEQLDESSV"
     exon            766..914
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            915..977
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1076
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1170
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1284
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1448
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1618
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1763
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1986
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            1987..2102
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2263
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..2325
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..4555
                     /gene="Sema4g"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4533..4538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sema4g"
                     /note="hexamer: AATAAA"
     polyA_site      4555
                     /gene="Sema4g"
                     /note="major polyA site"
ORIGIN      
        1 cccttcctcc tgcagctggt gctgtggggc cgcgagccgc acgtcgctgt ctctatggac
       61 ccggatccca gcgcaaagcc ggatggttaa tatttgaccc agaaggaaaa ggagaggcca
      121 gtgacaccct ctgaccctgc ctatggctgt ctgatgacat tgggtagatc aggcagcctc
      181 cacatctggc ccagccaagg aaatctccgg aagttccctg gcctatcaat ggcctccacc
      241 tcaggcgcgg ttctagtctt taagagaaca gacagagacc tggaacttgc cctgagactg
      301 ggggcaaggt gaccccttca gaaccctaca gtcctcctgg gaccctacac tgctcactct
      361 ccatggaatt tgcatttgat acagaaaggc acgtggtgac ccgcccttcc ctctgacttc
      421 ttacctgtga ttccatggcc acacaaccct gtggctccat gtccccccca ttccatgatc
      481 ctccatggcc ccatgactac ttgaccccca tgacctcatg acccctgacc cccatgagat
      541 cacaccctgg actttgaacc cagtgactgc tcttcccctc ccctcctgtg actctcctgg
      601 gctgccctcg gggtcttgtt ggtctgaact tccgcaggaa gatgtggggg aggctctggc
      661 ccctcctctt cagctttctc acagtaacag cagtgcctgg accctcactg cggagaccat
      721 cccgagagct agatgccacc ccacggctga ccatctccta tgaagagctc tcccagattc
      781 ggcacttcaa gggccaaacc cagaactatt caacactgct gctggaggag gcttctgaga
      841 ggctgctggt gggggctcga ggcgccctgt tctctctcag tgcccgtgac ataagagata
      901 ggactcacaa agagatccac tgggaggcct ccccagagat gcaaagcaag tgtcatcaga
      961 aagggaaaaa caaccagacc gagtgtttca accacgtgcg atttctacag cggctcaatg
     1021 ccacccactt ctatgcatgt gggacccacg ccttccagcc cctctgtgca gctattgatg
     1081 ctgaaacctt catcttgcct actagtttcg aggagggaaa ggagaaatgt ccttatgacc
     1141 cggcccgggg cttcacaggc cttatcattg atggaggcct ctacacagcc acccggtatg
     1201 aattccggag cattcctgat atccgccgga gccgccaccc acactctctg agaactgagg
     1261 aggcacccat gcactggctc aatgatgctg agtttgtgtt ctctgtgctg gtgcgggaga
     1321 gcaagacaag cgcagtgggt gatgatgaca agatttattt cttcttcatg gagcgtgagg
     1381 aaggctccag cagcttcaca cagagtcgca gcagccaccg tgtggctaga gtagcccgtg
     1441 tgtgcaaggg agatctggga gggaagaaga tcctacagaa gaagtggaca tccttcctga
     1501 aggctcgtct catctgccac atcccacagt atgagacact acgtggggtc tgcagcctga
     1561 atgctgatac atcatcccac acacatttct atgccgtctt cacactgaca acacagtgga
     1621 agacgctgga ggcttcagcc atctgccgct atgacctggc tgagattcag gctgtcttca
     1681 caggcccttt tatggagtac caggatggtg cccggcgctg gggccgctat gagggtgggg
     1741 tgcctgaacc ccggcctggc tcgtgcatca cagattcatt gcgcagccga ggctacaact
     1801 catcccaaga cttgccatcc ctggttctgg actttgtgaa gttgcatccc ctgatggctc
     1861 ggcctgtggt gcccacacgt gggcggccct tgctgctgaa gcgcaatgta cgctacacac
     1921 atctcacagg aacacacgtc agcacacctg ctggacccac ctatgacctg ctctttctgg
     1981 gcacagctga tggctggatc cacaaggccg tagtcctggg ctctgggatg cacataattg
     2041 aagagataca agtgttcagg gagccccagt ctgtggacaa tctagttatc tcaccaatgc
     2101 agcacagcct ctacgtgggg gctgcaagtg gagtcctcca gtttcctctg tccagctgct
     2161 cacgctacca gtcctgctat gactgcatcc tggcacggga cccctactgt ggctgggact
     2221 ccagcatcca tgcctgcatg gtggccacca ccgtagccaa caggacagaa ttgatacagg
     2281 acatagagag aggaaatcga ggctgtgagg gcagcaggga tgcaggacca ccaccaccac
     2341 tcaagacccg atctgtgctc cggggtgatg atgtcctcct gccctgtgac cagccgtcta
     2401 acctggcccg ggctttgtgg ctactcaatg ggagcaagag cctgagcgat gggcaggatg
     2461 gctaccgcgt gggagtggat gggctgctgg taactgacac acaactggag cacagtggca
     2521 actatggctg ctatgccgag gagaatggcc tccgtatgct gctggcgtcc tacagcctca
     2581 cagtccggcc agccacccct gctccagctc cacaagcccc tgccacacct ggggcacagc
     2641 tggcacatga catgaggatg ttctatgtgg tagccattgc tatacttggt ggcctctgcc
     2701 tcatcttggc atcttccctc ctctatgtgg cttgtctgaa gggaggcaga cgaggtcgaa
     2761 gacgaaaata ctcattgggt cgggctggcc gggcaggggg ctcggccgtg cagctgcaga
     2821 ctgtctcagg ccagtgtcct ggagaggaag atgaaggtga tgatggagaa ggaactgggg
     2881 gtctggagag tggctgcctc cagatcattc ccggggaagg agccccagcc ccaccacccc
     2941 caccaccccc acccccaccc gctgagctga ccaatgggct ggtggcactg cccagccggc
     3001 tgcgaaggat gaatggcaac agttatgtgc tcctgaggca gagcaacaat ggagtgccag
     3061 caggaccctg ctcctttgca gaggagctca gccgcatcct ggagaagagg aagcacacac
     3121 agcttgtaga gcaactagac gagagctctg tctgagtcta gccccgccaa acaaatgctc
     3181 ttccaagcca gcctggctgc cctaggctgg gccactgcct ccccaacacc tccaccctcc
     3241 tccatcctcc caattccatt tccttccaac tttttgatgt ctctgtaggg ctggccaaag
     3301 tcatggttag ccaaagtccc ctcttcagtc tccaagacac atgtgagcag cccaggccca
     3361 ccggtgctcc tcaaaggtag gtgctccccc agaaccaagt actcggcaaa cccaggccca
     3421 gtttctatcc cttgacctaa agacttggga ggagagaatt gtcttcttat cccgttatct
     3481 gcccaacctt cctcttcttc tcaggtaggg ctctgcaggt ccagatggcc tcaatgtcac
     3541 caccctctgc acagctgtgt gctgagtagt cctgaattca gacaagacct ctctctacca
     3601 gccacctgag tcctgcttcc attcacatgt gcacatggaa gaatgtttat cagctgggct
     3661 gcagtgtccc actcttcctc ctggggcacc cttgtctcac ctatcctaga ttcagggcac
     3721 cctctcaatt gccaccttgc tatctctttc cagccccagc cccgtgtggt aaccccctgg
     3781 caggagactg ggaggagaag catcagtgct ctccttcctc cgcagccctg gagtcagcct
     3841 ccctcctcct ctcattcaca tgtaaggctg ccagggctcc aggcatggcc tttcccagat
     3901 caagtgctta catttccacc cacatgtaca ttctgaactt cccccttgct gcctccgtca
     3961 gacctgtgtc tactaggttt ggtccatgga tatttcaaag gaagatttcc cttcccattt
     4021 atcggtcctc actgaactag gacaagtggc caacactgca ctcaatgagc cagcttccct
     4081 cttagggacc aagtgattgc ttctcctagg ccagagcagg aggaagtgat ctgctatctc
     4141 acctggcaca tgaagcccac tcctggaact atgcaaaggg cagaggctgg gcgtgtggat
     4201 gcttggctcc catccctgtc ctacctcacc agggcacttt caaggtccaa gggcctcaga
     4261 tgtctccagg cccacatggg acaatcaacc ctgactgagc cccccattcc tcttgggtga
     4321 ggatgactgt tatttttgta gctgagaacg tggaacccca cgagttttta ctgtccttca
     4381 cccatacctc tcccacctcc accccacaat gaatgtattt attgtgagaa tggctgtact
     4441 tcttcaggaa tgcccccact catcacccag gtgggtggaa caggcatgtg atggaatggg
     4501 gagcctgggc tctgctcctc ctgacattgg ctaataaatg ccctctttcc ccaca
//
