LOCUS       NM_028882               6521 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus sema domain, immunoglobulin domain (Ig), short basic
            domain, secreted, (semaphorin) 3D (Sema3d), mRNA.
ACCESSION   NM_028882
VERSION     NM_028882.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6521)
  AUTHORS   Thielman,N.R.J., Funes,V., Davuluri,S., Ibanez,H.E., Sun,W.C.,
            Fu,J., Li,K., Muth,S., Pan,X., Fujiwara,K., Dwayne L Thomas,Ii.,
            Henderson,M., Teh,S.S., Zhu,Q., Thompson,E., Jaffee,E.M.,
            Kolodkin,A., Meng,F. and Zheng,L.
  TITLE     Semaphorin 3D promotes pancreatic ductal adenocarcinoma progression
            and metastasis through macrophage reprogramming
  JOURNAL   Sci Adv 10 (42), eadp0684 (2024)
   PUBMED   39413197
  REMARK    GeneRIF: Semaphorin 3D promotes pancreatic ductal adenocarcinoma
            progression and metastasis through macrophage reprogramming.
REFERENCE   2  (bases 1 to 6521)
  AUTHORS   Qiu,C., Martin,B.K., Welsh,I.C., Daza,R.M., Le,T.M., Huang,X.,
            Nichols,E.K., Taylor,M.L., Fulton,O., O'Day,D.R., Gomes,A.R.,
            Ilcisin,S., Srivatsan,S., Deng,X., Disteche,C.M., Noble,W.S.,
            Hamazaki,N., Moens,C.B., Kimelman,D., Cao,J., Schier,A.F.,
            Spielmann,M., Murray,S.A., Trapnell,C. and Shendure,J.
  TITLE     A single-cell time-lapse of mouse prenatal development from
            gastrula to birth
  JOURNAL   Nature 626 (8001), 1084-1093 (2024)
   PUBMED   38355799
REFERENCE   3  (bases 1 to 6521)
  AUTHORS   Zhang,Y., Xi,Q., Zhong,M., Jiang,Y., Zhuang,Q., Ding,Z., Tan,S.,
            Wang,J., Liu,H., Zhang,Z., Zhou,B. and Wu,G.
  TITLE     Tumor-derived semaphorin 3D promoting cancer cachexia via
            regulating hypothalamic pro-opiomelanocortin neurons
  JOURNAL   FASEB J 37 (6), e22980 (2023)
   PUBMED   37219490
  REMARK    GeneRIF: Tumor-derived semaphorin 3D promoting cancer cachexia via
            regulating hypothalamic pro-opiomelanocortin neurons.
REFERENCE   4  (bases 1 to 6521)
  AUTHORS   Martins,L.F., Brambilla,I., Motta,A., de Pretis,S., Bhat,G.P.,
            Badaloni,A., Malpighi,C., Amin,N.D., Imai,F., Almeida,R.D.,
            Yoshida,Y., Pfaff,S.L. and Bonanomi,D.
  TITLE     Motor neurons use push-pull signals to direct vascular remodeling
            critical for their connectivity
  JOURNAL   Neuron 110 (24), 4090-4107 (2022)
   PUBMED   36240771
REFERENCE   5  (bases 1 to 6521)
  AUTHORS   Shao,A., Gearhart,M.D., Chan,S.C., Miao,Z., Susztak,K. and
            Igarashi,P.
  TITLE     Multiomics analysis reveals that hepatocyte nuclear factor 1beta
            regulates axon guidance genes in the developing mouse kidney
  JOURNAL   Sci Rep 12 (1), 17586 (2022)
   PUBMED   36266461
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6521)
  AUTHORS   Chung,L., Yang,T.L., Huang,H.R., Hsu,S.M., Cheng,H.J. and
            Huang,P.H.
  TITLE     Semaphorin signaling facilitates cleft formation in the developing
            salivary gland
  JOURNAL   Development 134 (16), 2935-2945 (2007)
   PUBMED   17626059
REFERENCE   7  (bases 1 to 6521)
  AUTHORS   Chen,B., Schaevitz,L.R. and McConnell,S.K.
  TITLE     Fezl regulates the differentiation and axon targeting of layer 5
            subcortical projection neurons in cerebral cortex
  JOURNAL   Proc Natl Acad Sci U S A 102 (47), 17184-17189 (2005)
   PUBMED   16284245
REFERENCE   8  (bases 1 to 6521)
  AUTHORS   Cohen,S., Funkelstein,L., Livet,J., Rougon,G., Henderson,C.E.,
            Castellani,V. and Mann,F.
  TITLE     A semaphorin code defines subpopulations of spinal motor neurons
            during mouse development
  JOURNAL   Eur J Neurosci 21 (7), 1767-1776 (2005)
   PUBMED   15869472
REFERENCE   9  (bases 1 to 6521)
  AUTHORS   Gu,C., Yoshida,Y., Livet,J., Reimert,D.V., Mann,F., Merte,J.,
            Henderson,C.E., Jessell,T.M., Kolodkin,A.L. and Ginty,D.D.
  TITLE     Semaphorin 3E and plexin-D1 control vascular pattern independently
            of neuropilins
  JOURNAL   Science 307 (5707), 265-268 (2005)
   PUBMED   15550623
REFERENCE   10 (bases 1 to 6521)
  AUTHORS   Tarantino,L.M., Feiner,L., Alavizadeh,A., Wiltshire,T., Hurle,B.,
            Ornitz,D.M., Webber,A.L., Raper,J., Lengeling,A., Rowe,L.B. and
            Bucan,M.
  TITLE     A high-resolution radiation hybrid map of the proximal portion of
            mouse chromosome 5
  JOURNAL   Genomics 66 (1), 55-64 (2000)
   PUBMED   10843805
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052671.1, AK163828.1 and CF746948.1.
            
            On Jan 1, 2010 this sequence version replaced NM_028882.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK031704.1, AK028900.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3316              AK052671.1         2-3317
            3317-6330           AK163828.1         1109-4122
            6331-6521           CF746948.1         347-537
FEATURES             Location/Qualifiers
     source          1..6521
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 3.97 cM"
     gene            1..6521
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="sema domain, immunoglobulin domain (Ig), short
                     basic domain, secreted, (semaphorin) 3D"
                     /db_xref="GeneID:108151"
                     /db_xref="MGI:MGI:1860118"
     exon            1..509
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            510..697
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             547..2880
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="semaphorin-3D"
                     /codon_start=1
                     /product="semaphorin-3D precursor"
                     /protein_id="NP_083158.3"
                     /db_xref="CCDS:CCDS39013.1"
                     /db_xref="GeneID:108151"
                     /db_xref="MGI:MGI:1860118"
                     /translation="MNVTKDENPRSRSQDLHLFHAWMMLIMTVLFLPVTETSKQNIPR
                     LKLTYKDLLLSNTCIPFLGSSEGLDFQTLLLDEERGILLLGAKDHVFLLSLVDLNKNF
                     KKIYWPAAKERVELCKLAGKDANAECANFIRVLQPYNKTHVYVCGTGAFHPLCGYIDL
                     GANKEELIFKLDTHNLESGRLKCPFDPQQPFASVMTDEHLYSGTASDFLGKDTAFTRS
                     LGLMQDHHSIRTDISEHHWLNGAKFIGTFPIPDTYNPDDDKIYFFFRESSQEGSTSDR
                     SILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTR
                     DERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRIPY
                     PRPGTCPSKTYDPLIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLT
                     QIVVDHVVAEDGQYDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQVFKHPTAILN
                     MELSLKQQQLYVGSWDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTS
                     KRRARRQDVKYGDPITQCWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQASVEW
                     YIQRSGDEHREELKPDERIIKTDYGLLIRSLQKKDSGMYYCKAQEHTFIHTIVKLTLN
                     VIENEQMENTQRAEYQEGQVKDLLAESRLRYKDYIQILSSPNFSLDQYCEQMWYKEKR
                     RQRNKGSPKWKHMQEMKKKRNRRHHRDLDELQRSVAT"
     exon            698..858
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            859..921
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1041
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1135
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1264
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1407
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1522
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1592
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..1737
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1960
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2049
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2091
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2092..2249
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2250..2314
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2315..2454
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..6521
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3869..3874
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="hexamer: AATATA"
     polyA_site      3888
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="major polyA site"
     regulatory      6339..6344
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6359
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="major polyA site"
     regulatory      6491..6496
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6520
                     /gene="Sema3d"
                     /gene_synonym="4631426B19Rik"
ORIGIN      
        1 aaacccaccc tggacagcgc ggccgagaca gggaaggttt gctcgctctg agggattgcc
       61 agcacatcag aagtggccgg gagctggggg aggagactga agggagaggt aatccctggc
      121 gttttgagca tccccttttt agaaagaagg agtctctccc aggacagctg ctgcggtcac
      181 accacaaact taaaagccgc cctcctgctt ggagcgtgcc tttcctcacc acgctcgctg
      241 gcctaagcgc caactggtgg gtcactgtcc gagagagagg cgctgcgctc gggggacagg
      301 agcgccccct gccttcccgc ttggccgtag ccgcggcctc attgctctgc cagggccgcc
      361 tgtgcggggt tcagccccgg ctgccgctcc gaagaactcg cgcctgtgcc cgcggtcgcc
      421 atcctcttgg cttccttggg ctgtcctttc ctctctcctg agcctgcgac gtaaggaaag
      481 gaaaagcgac aagagttgct agcaggaagg gtgaactaac agtgtttgaa aaacaaaatt
      541 ttcatcatga atgttactaa agatgagaac ccaagatcca gaagtcaaga tcttcacctt
      601 tttcatgctt ggatgatgtt aatcatgacg gtgctctttc ttcctgtcac tgaaacgtct
      661 aaacaaaata ttccaagact caagctaacc tacaaagact tgctgctttc aaacacctgt
      721 atcccctttt tgggttcatc agaaggattg gatttccaga ctcttctttt ggatgaggag
      781 aggggcatac tgctcctagg agccaaagac catgtcttcc tgctcagtct ggttgacttg
      841 aacaagaatt ttaagaagat ttattggcct gctgcaaaag aacgagtgga gctatgtaaa
      901 ttagctggga aagatgccaa tgcagaatgt gcaaatttca tccgtgtgct tcaaccctat
      961 aataagactc acgtttacgt gtgtggaact ggagcgtttc atccgctgtg tgggtacatt
     1021 gatctcggcg ccaacaagga ggaactcata tttaaactag acacgcacaa cctggagtct
     1081 ggcagactga aatgtccctt tgatcctcag cagccttttg cttcagtaat gacagatgag
     1141 cacctctact ctggaacagc ttctgatttc cttggcaaag acactgcatt cacaaggtct
     1201 ctggggctaa tgcaggacca ccattccatc agaactgaca tttcagagca ccactggctc
     1261 aatggagcaa aatttatcgg aacattcccc attccagaca cctataatcc agatgatgat
     1321 aaaatatatt tcttctttcg agaatcatcc caggaaggca gtacttctga cagaagcatt
     1381 ctttcaagag ttggaagagt ttgtaagaat gatgtaggtg ggcaacgaag tctgataaac
     1441 aaatggacaa cttttctaaa ggcaagactg atttgctcga ttcctggaag cgatggggca
     1501 gatacccatt ttgatgaact ccaagatatt tacttactcc ctacgagaga tgaaagaaat
     1561 cctgtagtat atggagtctt taccacaacc agctccatct tcaaaggctc tgctgtctgt
     1621 gtgtacagca tggctgatat ccgagcagtc tttaatggtc cctatgctca taaggaaagt
     1681 gctgaccatc gctgggtgca atatgatgga aggatacctt acccccgacc tggaacgtgt
     1741 ccaagcaaaa cctatgaccc actgattaag tccacccgag actttccaga cgatgttatc
     1801 agtttcataa ggcggcaccc tgtgatgtat aagtccgtgt acccagtggc aggagcaccg
     1861 accttcaaga gaatcaacgt ggattacaga ctgacgcaga tagtggtgga tcacgtggtc
     1921 gctgaagacg ggcagtatga tgtcatgttt ctcggaacag acattggaac agtcctgaaa
     1981 gttgtgagca tctccaagga gaagtggaat atggaagagg tcgtactgga ggagcttcag
     2041 gtattcaagc acccaacagc tatcttgaac atggagttgt cgctgaagca gcaacagttg
     2101 tacgttggtt cctgggatgg attggtccag ctctccttgc acagatgcga cacttacggg
     2161 aaagcatgtg cagactgctg tctcgccaga gacccttact gtgcctggga tggaaatgct
     2221 tgctccagat atgcacccac gtctaaaagg cgagctagac gccaggatgt aaaatatggg
     2281 gacccaatca ctcagtgctg ggacatagaa gacagcatta gtcatgaaac agctgatgaa
     2341 aaggtgattt ttggaattga atttaattca acctttttgg agtgtatacc taaatcccaa
     2401 caagcctctg ttgagtggta catccagcgg tcaggagatg agcatcgaga ggagttgaaa
     2461 cctgatgaaa ggatcatcaa aactgactat gggctactga ttcgaagtct gcagaagaag
     2521 gattctggga tgtattactg caaagcacag gagcacactt tcatccacac catagtgaag
     2581 ctgactttga atgtcattga gaatgaacag atggaaaata cccagagggc agaataccag
     2641 gaggggcagg tcaaggatct gttggctgag tcacggttga gatacaaaga ctacatccaa
     2701 atccttagca gcccgaactt cagcctggac cagtactgtg agcagatgtg gtacaaggag
     2761 aagcggagac agcgcaacaa gggcagccca aagtggaagc acatgcagga aatgaagaag
     2821 aaacgaaatc gacgacatca cagagacctc gatgagctcc agagatcagt agctacatag
     2881 ttttctattt aatttaaaga gggaattatt tacctgcctg cacaaataat gtcttctgtt
     2941 ttgtacatcc cttatactaa ctcatacatg cttcccatgg agtctcacgg aggcacagga
     3001 tgctatgctg agtaagacta tataggacat catctgaacc agctttccaa gaacaaaatc
     3061 tgtatcagca aagttaagaa ttgtcttaaa aataggggcc ttatgtttgt aaatgtctca
     3121 tagtttgaat ttaatgtcat gtaaataatc aagttaaatg aacccaggtc cacttagtaa
     3181 gggcgttatt cccgtgcatg tccattaagc atggactttc ccatgctgct ggctatgtgc
     3241 ttaatcattc cattctagaa caggtgatca tgtaggaact ggagaaaagg cacactttaa
     3301 aacagcttat gttagcaaaa aaaaaacttt ctcaaggagc caacaggcca cacttggagt
     3361 caggcgtggg aatttagaaa ggcatgttcc ctctttgtgg accaggctac atctagtgta
     3421 ctgcagtaat gctctgtgag agggtagtaa tgatcctcac caatttcctt ttgattgctc
     3481 aagcacagca tcatggacag aaccccatgg tgtgctctag agtacagaca atggaactta
     3541 gtacacactt cctgtgctct ttgggaagca tggtaaaaga tcttaatata ataataaggg
     3601 tgacatgata tacactgtat cctaatctgt agatgggaat tatttggaga cagacaagat
     3661 agctgtaaat tctgtctctg agaaaaactt atattgccat aaaaaaggag aaagccacaa
     3721 agtagataga atgtaatgga attctttcca ctggagtata aatatctgcc aacttataat
     3781 gttttggtta aaaataattt agattatagc aaattgttag caaaaatgca agtgaaagta
     3841 aaatttgtaa aaaaaattat gggatggcaa tatattattt ataaccaatg tatttctgtg
     3901 ttctcttttt ttctaagtat ttatcgtatt ctgtatattg tttgcattta catccttttt
     3961 tttattatat ttgagtaaat aggagaaagc aatacgtaat acatagagat aattgagtag
     4021 atgaccaagg tggggagtgg ggctatatat ttgttgaatg gatggataat ggcaaaattt
     4081 tgatgacggg aagggttaaa ttaactcttc gacatcctct cgttacataa actttcaagc
     4141 agtgttgttt tcagcagttt cacaaggaag tcttcaacat ctaaagaaaa cactcacacc
     4201 gttagcataa gtaccatttg tattttgcta gcctgtgtca aattcaactt tgcctttgaa
     4261 cagtgttttc ctgccagtct ctccagaaat caactttcct tcctgtagca caaaaccctt
     4321 agccttcctc tgttttgcct tttcacgctc tttatagtgt gaaatgaaca attagtcact
     4381 tcctcacaaa gaatgcagct ttttagaaaa ccaacagacc ttgtttgttt ctcatgcatt
     4441 ctacatgttt tgaaagattc tgtgagaagc ctgtgtgatt aaaaagcagt tttacagagt
     4501 caagcaatct atctcttcaa agtagcatca gtattttaca ttcatttaat ttgcattggg
     4561 tacctatctc aagggcataa cattatctgc aagggactag tataataatg aatatttgtt
     4621 gatgtttcac tcttggaaaa agcaaaaatg aaggaacaat tttaatttgt aaaccagaat
     4681 gaatcacatc tccagcagaa gtgcatacaa atccttgtgt catggttaga ctactaatca
     4741 tagatcacac aataatgttt atctactggc ttactgagtc ctgcaaagtc acagcaaaca
     4801 tgtcagtggg tgcatgcttc attcaaaaaa tgctttcaga tagctgtgca tcagagagta
     4861 atactcaaat atcagtagta ttgaaagatt gcacaagatt ctactctttg tattgacatc
     4921 tgaaaattaa ttttatatag ataataatgt ccaaactatt ttctaattac ttatgtaatt
     4981 agaaatgtaa tgttttatca acattctgta aatctatttt acatcttaga tttaaaattt
     5041 tggctgtttt gggcataaaa cttctaatta tgattaaata tattataaac attattagga
     5101 aaatatgatt ccataataaa ggtagggcta tggtttattt tgaaatgcag actatagcta
     5161 agcagcattc attcttattc aaaagactta gaagagtgtt gtgaaagatc agttgacaaa
     5221 tgtaatgtgt agttccttac cattgaggat gaacaactct gttttgaaat aataaaaagc
     5281 agaatattgc tcaaagttta aatattaaag gtaccagatc ccccagaagc aactctgaac
     5341 tatgtagtta ttcatttttt tttaaatcta tttttctgtc ttcagtacaa gtctctagct
     5401 tctgtgagtg tttttgctgc atttttattc agtcctttgt gctgctaaat agtagtatgc
     5461 ctgaatgagt taatttacat ttaatttatt gggaatttta agagtttgtt tagaaatgga
     5521 taatctaaat aagcaattta tgtaaaatcc tttgtttttc tttcccaaaa gagttcataa
     5581 tcatatatca cacgacagag taaacatttc agaagaaaca gtcaagttac ttaaaaaact
     5641 gcaaagtagt catagaaaaa ctgagcacac tgcagaatcc acaatagctc tcggatgcac
     5701 aattccagga tgatttgttt aaagcaagac ttacttacaa catgcctgca atatgatggt
     5761 cacgcttttg gacgtttcct ttgtgctata ctttgattct ttgcatatat taattattac
     5821 atgctattcc tactgaattg gtgatcttac ctagaggcta acaagagtga ctacttgtta
     5881 gactaacata accaagaata atttcccagg acaacttgtg tcatttcatt cacatgaaaa
     5941 aataaaatta aacaagacca ctcagtaaac attgattctt cttaaacata tgtctaagat
     6001 gtattgtaca tattttactg aaacagaata aagttaactt gggaatccct tctcttcata
     6061 ataccacatt gttgcagtca gtgtgtttca actaacaagc cattttgagg gatgggtaac
     6121 tttttaaaaa tagaaatgta tattttctca taatagatga tcacaatatt tcaatttaca
     6181 gtatgtaagg ttaaaaatac ataagactta aattttccag acttgttaaa ctgaaaatcc
     6241 atgtacacaa taaatctcac gctttgtaac tcttgcttaa atcttttgta atgtaaggta
     6301 tttatgaaaa tttgaagcat acctttttgg gaaagaaaaa taaaacctgt cagaagccac
     6361 agttggtctt cacttcttag cattgtcagt ggtgggtatc aatgaatttg aataatttta
     6421 cttttaaaaa actgtagtct tgtagtatag catacttaaa attgttaaat gtatattttg
     6481 tttgtattat aataaaacaa gtatcagtgt tctattatta t
//
