LOCUS       NP_033177                417 aa            linear   ROD 07-OCT-2024
DEFINITION  P-selectin glycoprotein ligand 1 precursor [Mus musculus].
ACCESSION   NP_033177
VERSION     NP_033177.3
DBSOURCE    REFSEQ: accession NM_009151.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 417)
  AUTHORS   Jiang,C., Mei,M., Liu,Y., Hou,M., Jiao,J., Tan,Y. and Tan,X.
  TITLE     PSGL-1 is an evolutionarily conserved antiviral restriction factor
  JOURNAL   mBio 14 (5), e0038723 (2023)
   PUBMED   37787515
  REMARK    GeneRIF: PSGL-1 is an evolutionarily conserved antiviral
            restriction factor.
REFERENCE   2  (residues 1 to 417)
  AUTHORS   Xu,Q., Shi,M., Ding,L., Xia,Y., Luo,L., Lu,X., Zhang,X. and
            Deng,D.Y.B.
  TITLE     High expression of P-selectin induces neutrophil extracellular
            traps via the PSGL-1/Syk/Ca2+/PAD4 pathway to exacerbate acute
            pancreatitis
  JOURNAL   Front Immunol 14, 1265344 (2023)
   PUBMED   37841279
  REMARK    GeneRIF: High expression of P-selectin induces neutrophil
            extracellular traps via the PSGL-1/Syk/Ca[2+]/PAD4 pathway to
            exacerbate acute pancreatitis.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 417)
  AUTHORS   Goth,C.K., Mehta,A.Y., McQuillan,A.M., Baker,K.J., Hanes,M.S.,
            Park,S.S., Stavenhagen,K., Hjorto,G.M., Heimburg-Molinaro,J.,
            Chaikof,E.L., Rosenkilde,M.M. and Cummings,R.D.
  TITLE     Chemokine binding to PSGL-1 is controlled by O-glycosylation and
            tyrosine sulfation
  JOURNAL   Cell Chem Biol 30 (8), 893-905 (2023)
   PUBMED   37463583
  REMARK    GeneRIF: Chemokine binding to PSGL-1 is controlled by
            O-glycosylation and tyrosine sulfation.
REFERENCE   4  (residues 1 to 417)
  AUTHORS   Hope,J.L., Otero,D.C., Bae,E.A., Stairiker,C.J., Palete,A.B.,
            Faso,H.A., Lin,M., Henriquez,M.L., Roy,S., Seo,H., Lei,X.,
            Wang,E.S., Chow,S., Tinoco,R., Daniels,G.A., Yip,K., Campos,A.R.,
            Yin,J., Adams,P.D., Rao,A. and Bradley,L.M.
  TITLE     PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell
            progenitor differentiation and elicit terminal CD8+ T cell
            exhaustion
  JOURNAL   Cell Rep 42 (5), 112436 (2023)
   PUBMED   37115668
REFERENCE   5  (residues 1 to 417)
  AUTHORS   Harbour,J.C., Abdelbary,M., Schell,J.B., Fancher,S.P., McLean,J.J.,
            Nappi,T.J., Liu,S., Nice,T.J., Xia,Z., Fruh,K. and Nolz,J.C.
  TITLE     T helper 1 effector memory CD4+ T cells protect the skin from
            poxvirus infection
  JOURNAL   Cell Rep 42 (5), 112407 (2023)
   PUBMED   37083328
REFERENCE   6  (residues 1 to 417)
  AUTHORS   van den Berg,T.K., Nath,D., Ziltener,H.J., Vestweber,D., Fukuda,M.,
            van Die,I. and Crocker,P.R.
  TITLE     Cutting edge: CD43 functions as a T cell counterreceptor for the
            macrophage adhesion receptor sialoadhesin (Siglec-1)
  JOURNAL   J Immunol 166 (6), 3637-3640 (2001)
   PUBMED   11238599
REFERENCE   7  (residues 1 to 417)
  AUTHORS   Hirata,T., Merrill-Skoloff,G., Aab,M., Yang,J., Furie,B.C. and
            Furie,B.
  TITLE     P-Selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand
            for E-selectin in mediating T helper 1 lymphocyte migration
  JOURNAL   J Exp Med 192 (11), 1669-1676 (2000)
   PUBMED   11104809
REFERENCE   8  (residues 1 to 417)
  AUTHORS   Norman,K.E., Katopodis,A.G., Thoma,G., Kolbinger,F., Hicks,A.E.,
            Cotter,M.J., Pockley,A.G. and Hellewell,P.G.
  TITLE     P-selectin glycoprotein ligand-1 supports rolling on E- and
            P-selectin in vivo
  JOURNAL   Blood 96 (10), 3585-3591 (2000)
   PUBMED   11071658
REFERENCE   9  (residues 1 to 417)
  AUTHORS   Yang,J., Hirata,T., Croce,K., Merrill-Skoloff,G., Tchernychev,B.,
            Williams,E., Flaumenhaft,R., Furie,B.C. and Furie,B.
  TITLE     Targeted gene disruption demonstrates that P-selectin glycoprotein
            ligand 1 (PSGL-1) is required for P-selectin-mediated but not
            E-selectin-mediated neutrophil rolling and migration
  JOURNAL   J Exp Med 190 (12), 1769-1782 (1999)
   PUBMED   10601352
REFERENCE   10 (residues 1 to 417)
  AUTHORS   Yang,J., Galipeau,J., Kozak,C.A., Furie,B.C. and Furie,B.
  TITLE     Mouse P-selectin glycoprotein ligand-1: molecular cloning,
            chromosomal localization, and expression of a functional P-selectin
            receptor
  JOURNAL   Blood 87 (10), 4176-4186 (1996)
   PUBMED   8639776
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ134610.1, BE859840.1, BG083864.2, BG070861.2, BY553294.1 and
            AC159240.3.
            
            On Nov 2, 2007 this sequence version replaced NP_033177.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK156933.1, AK155762.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 55.59 cM"
     Protein         1..417
                     /product="P-selectin glycoprotein ligand 1 precursor"
                     /note="P-selectin glycoprotein ligand 1; selectin P
                     ligand"
                     /calculated_mol_wt=42124
     sig_peptide     1..17
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=1746
     Region          <133..276
                     /region_name="rne"
                     /note="ribonuclease E; Reviewed; PRK10811"
                     /db_xref="CDD:236766"
     CDS             1..417
                     /gene="Selplg"
                     /gene_synonym="CD162; Psgl-1; Psgl1; Selp1; Selpl"
                     /coded_by="NM_009151.3:159..1412"
                     /db_xref="CCDS:CCDS51621.1"
                     /db_xref="GeneID:20345"
                     /db_xref="MGI:MGI:106689"
ORIGIN      
        1 mspsflvllt ilgpgnslql qdpwghetke apgpvhlrer rqvvgdddfe dpdytyntdp
       61 pellknvtnt vaahpelptt vvmlerdsts agtseratek iattdptapg tggtavgmls
      121 tdsatqwslt svetvqpast evetsqpapm eaetsqpapm eaetsqpapm eaetsqpapm
      181 eadtsqpapm eadtskpapt eaetskpapt eaetsqpapn eaetskpapt eaetskpapt
      241 eaettqlpri qavktlftts aatevpstep ttmetastes nestiflgps vthlpdsglk
      301 kglivtpgns paptlpgssd lipvkqclli ililaslati flvctvvlav rlsrkthmyp
      361 vrnysptemi cissllpegg dgapvtangg lpkvqdlkte psgdrdgddl tlhsflp
//
