LOCUS       NM_027652               6806 bp    mRNA    linear   ROD 15-OCT-2024
DEFINITION  Mus musculus selenoprotein I (Selenoi), transcript variant 1, mRNA.
ACCESSION   NM_027652
VERSION     NM_027652.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6806)
  AUTHORS   Huang,X., Li,T., Yang,S.H., Zhu,K.D., Wang,L.S., Dong,Y.L. and
            Huang,J.Q.
  TITLE     Hepatocyte-specific Selenoi deficiency predisposes mice to hepatic
            steatosis and obesity
  JOURNAL   FASEB J 38 (11), e23717 (2024)
   PUBMED   38837270
  REMARK    GeneRIF: Hepatocyte-specific Selenoi deficiency predisposes mice to
            hepatic steatosis and obesity.
REFERENCE   2  (bases 1 to 6806)
  AUTHORS   Nunes,L.G.A., Ma,C., Hoffmann,F.W., Shay,A.E., Pitts,M.W. and
            Hoffmann,P.R.
  TITLE     Selenoprotein I is indispensable for ether lipid homeostasis and
            proper myelination
  JOURNAL   J Biol Chem 300 (5), 107259 (2024)
   PUBMED   38582453
  REMARK    GeneRIF: Selenoprotein I is indispensable for ether lipid
            homeostasis and proper myelination.
REFERENCE   3  (bases 1 to 6806)
  AUTHORS   Ma,C., Hoffmann,F.W., Nunes,L.G., Urena,F., Andrukhiv,A.,
            Gerschenson,M., Pitts,M.W. and Hoffmann,P.R.
  TITLE     Selenoprotein I deficiency in T cells promotes differentiation into
            tolerant phenotypes while decreasing Th17 pathology
  JOURNAL   J Leukoc Biol 112 (6), 1387-1397 (2022)
   PUBMED   35916034
  REMARK    GeneRIF: Selenoprotein I deficiency in T cells promotes
            differentiation into tolerant phenotypes while decreasing Th17
            pathology.
REFERENCE   4  (bases 1 to 6806)
  AUTHORS   Nunes,L.G.A., Pitts,M.W. and Hoffmann,P.R.
  TITLE     Selenoprotein I (selenoi) as a critical enzyme in the central
            nervous system
  JOURNAL   Arch Biochem Biophys 729, 109376 (2022)
   PUBMED   36007576
  REMARK    GeneRIF: Selenoprotein I (selenoi) as a critical enzyme in the
            central nervous system.
REFERENCE   5  (bases 1 to 6806)
  AUTHORS   Ma,C., Hoffmann,F.W., Marciel,M.P., Page,K.E., Williams-Aduja,M.A.,
            Akana,E.N.L., Gojanovich,G.S., Gerschenson,M., Urschitz,J.,
            Moisyadi,S., Khadka,V.S., Rozovsky,S., Deng,Y., Horgen,F.D. and
            Hoffmann,P.R.
  TITLE     Upregulated ethanolamine phospholipid synthesis via selenoprotein I
            is required for effective metabolic reprogramming during T cell
            activation
  JOURNAL   Mol Metab 47, 101170 (2021)
   PUBMED   33484950
REFERENCE   6  (bases 1 to 6806)
  AUTHORS   Avery,J.C., Yamazaki,Y., Hoffmann,F.W., Folgelgren,B. and
            Hoffmann,P.R.
  TITLE     Selenoprotein I is essential for murine embryogenesis
  JOURNAL   Arch Biochem Biophys 689, 108444 (2020)
   PUBMED   32502470
  REMARK    GeneRIF: Selenoprotein I is essential for murine embryogenesis.
REFERENCE   7  (bases 1 to 6806)
  AUTHORS   Gladyshev,V.N., Arner,E.S., Berry,M.J., Brigelius-Flohe,R.,
            Bruford,E.A., Burk,R.F., Carlson,B.A., Castellano,S., Chavatte,L.,
            Conrad,M., Copeland,P.R., Diamond,A.M., Driscoll,D.M., Ferreiro,A.,
            Flohe,L., Green,F.R., Guigo,R., Handy,D.E., Hatfield,D.L.,
            Hesketh,J., Hoffmann,P.R., Holmgren,A., Hondal,R.J., Howard,M.T.,
            Huang,K., Kim,H.Y., Kim,I.Y., Kohrle,J., Krol,A., Kryukov,G.V.,
            Lee,B.J., Lee,B.C., Lei,X.G., Liu,Q., Lescure,A., Lobanov,A.V.,
            Loscalzo,J., Maiorino,M., Mariotti,M., Sandeep Prabhu,K.,
            Rayman,M.P., Rozovsky,S., Salinas,G., Schmidt,E.E., Schomburg,L.,
            Schweizer,U., Simonovic,M., Sunde,R.A., Tsuji,P.A., Tweedie,S.,
            Ursini,F., Whanger,P.D. and Zhang,Y.
  TITLE     Selenoprotein Gene Nomenclature
  JOURNAL   J Biol Chem 291 (46), 24036-24040 (2016)
   PUBMED   27645994
REFERENCE   8  (bases 1 to 6806)
  AUTHORS   Kryukov,G.V., Castellano,S., Novoselov,S.V., Lobanov,A.V.,
            Zehtab,O., Guigo,R. and Gladyshev,V.N.
  TITLE     Characterization of mammalian selenoproteomes
  JOURNAL   Science 300 (5624), 1439-1443 (2003)
   PUBMED   12775843
REFERENCE   9  (bases 1 to 6806)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC241618.4, BY136287.1,
            AK122544.1, BC078438.1 and AK133635.1.
            
            On Jul 6, 2016 this sequence version replaced NM_027652.2.
            
            Summary: The multi-pass transmembrane protein encoded by this gene
            belongs to the CDP-alcohol phosphatidyltransferase class-I family.
            It catalyzes the transfer of phosphoethanolamine from
            CDP-ethanolamine to diacylglycerol to produce
            phosphatidylethanolamine, which is involved in the formation and
            maintenance of vesicular membranes, regulation of lipid metabolism,
            and protein folding. This protein is a selenoprotein, containing
            the rare selenocysteine (Sec) amino acid at its active site. Sec is
            encoded by the UGA codon, which normally signals translation
            termination. The 3' UTRs of selenoprotein mRNAs contain a conserved
            stem-loop structure, designated the Sec insertion sequence (SECIS)
            element, that is necessary for the recognition of UGA as a Sec
            codon rather than as a stop signal. Alternatively spliced
            transcript variants have been found for this gene. [provided by
            RefSeq, Jul 2016].
            
            Transcript Variant: This variant (1) represents the selenoprotein
            encoding transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122544.1, BC106097.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            protein contains selenocysteine :: inferred from conservation
            RefSeq Select criteria          :: based on single protein-coding
                                               transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                AC241618.4         56344-56380         c
            38-121              BY136287.1         1-84
            122-4602            AK122544.1         1-4481
            4603-6803           BC078438.1         355-2555
            6804-6806           AK133635.1         3211-3213
FEATURES             Location/Qualifiers
     source          1..6806
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 16.22 cM"
     gene            1..6806
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /note="selenoprotein I"
                     /db_xref="GeneID:28042"
                     /db_xref="MGI:MGI:107898"
     exon            1..235
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..1375
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /EC_number="2.7.8.1"
                     /note="UGA stop codon recoded as selenocysteine;
                     ethanolaminephosphotransferase 1
                     (CDP-ethanolamine-specific)"
                     /codon_start=1
                     /transl_except=(pos:1340..1342,aa:Sec)
                     /product="ethanolaminephosphotransferase 1"
                     /protein_id="NP_081928.2"
                     /db_xref="CCDS:CCDS51451.1"
                     /db_xref="GeneID:28042"
                     /db_xref="MGI:MGI:107898"
                     /translation="MAGYEYVSPEQLSGFDKYKYSALDTNPLSLYIMHPFWNTIVKVF
                     PTWLAPNLITFSGFMLLVFNFLLLTYFDPDFYASAPGHKHVPDWVWIVVGILNFAAYT
                     LDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRGPTGVSVFVLYLLL
                     WVVLFSFILSHWEKYNTGVLFLPWGYDISQVTISFVYIVTAVVGVEAWYEPFLFNFLY
                     RDLFTAMIIGCALCVTLPMSLLNFFRSYKSNTLKHKSVYEAMVPFFSPCLLFTLCTVW
                     ILWSPSDILEIHPRIFYFMVGTAFANITCQLIVCQMSSTRCPTLNWLLLPLLLVVAAV
                     IVGAATSRLESALLYTLTAAFTLAHIHYGVQVVKQLSRHFQIYPFSLRKPNSDULGME
                     EQNIGL"
     exon            236..304
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            305..413
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            414..488
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            489..751
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            752..860
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            861..909
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1090
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1276
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..6806
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2596..2673
                     /regulatory_class="recoding_stimulatory_region"
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /note="SECIS_element"
                     /function="essential for recoding UGA to specify
                     selenocysteine"
     regulatory      3331..3336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /note="hexamer: AGTAAA"
     polyA_site      3350
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /note="major polyA site"
     regulatory      6783..6788
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
                     /note="hexamer: AATAAA"
     polyA_site      6803
                     /gene="Selenoi"
                     /gene_synonym="4933402G07Rik; D5Wsu178e; Ept1; mKIAA1724;
                     SELI"
ORIGIN      
        1 gggctgcgct tgcgcactgg gtgcgctacg cgtgcgcggt gggcggagcg cgcctctacc
       61 ttctttacca gcccaggctt tcctagctct gcacaacgcc gtgtgctgct cctgtttcat
      121 tgccctgtcg cgcagtgtcg ctgccgctgc ggagtgggcg ttcagttttc gggtcgtcat
      181 ggctggctac gaatacgtga gcccagagca gctgtcgggc tttgacaagt acaagtacag
      241 cgctttggat accaacccac tctctctgta tatcatgcat ccattttgga acactatagt
      301 gaaggtgttt cctacttggc tggctcccaa tcttataacc ttttctggct ttatgctgct
      361 tgtgttcaat ttcctactcc tgacatactt cgaccctgac ttctatgctt cagcccctgg
      421 tcataagcat gtgcctgact gggtttggat tgtcgtgggc atcctcaact ttgctgccta
      481 cactctagat ggagtggatg gaaagcaagc acggagaacc aattccagca ccccgttagg
      541 ggagctgttt gaccatggcc tggacagttg gtcgtgtgtt tactttgttg tgactgtgta
      601 ctccatcttt ggacgaggac cgactggcgt cagtgttttt gttctttatc tcctgctatg
      661 ggtagttttg ttttctttta tcctgtctca ctgggagaag tataacacag gcgttctttt
      721 cctgccatgg ggatatgaca ttagccaagt gactatttct tttgtctaca tagtgactgc
      781 ggttgtggga gttgaggcct ggtatgaacc tttcctgttt aatttcttat atagagacct
      841 attcactgca atgattattg ggtgtgcatt atgtgtgact cttccaatga gtttattaaa
      901 cttttttaga agctataaaa gcaacacgct gaagcacaag tccgtctatg aagccatggt
      961 ccccttcttc tctccgtgtt tgctcttcac tttgtgtaca gtgtggatcc tctggtcacc
     1021 ttcagatatc ttagaaatac accctagaat attctacttc atggttggaa cagcttttgc
     1081 caatatcaca tgtcagctaa ttgtttgcca aatgagcagc acgcggtgcc cgactttgaa
     1141 ctggttactg cttcctctcc tcttggttgt ggcagcggtg atcgtaggtg cagccacctc
     1201 ccgccttgag agcgccctcc tttacacact cacggctgcc ttcactctgg ctcacatcca
     1261 ttatggcgta caagtggtga agcagctgag ccgacatttt cagatttatc ctttttcatt
     1321 gaggaaacca aactcagatt gactaggaat ggaagaacag aatatcggcc tgtaatcttg
     1381 acaaagtact gtaaatagat gcgtgtaaat acttcatcca tcaccagtga actgaacgga
     1441 tctgctcggc agacatggga tctcagtgtg tgctatatgg acagcaagaa tgaaacctgg
     1501 gctcagcttg tggaattgtg gactttctaa ctcccagctt actctatttt attttatttt
     1561 ttttatagag ccatgagaca tttggttaag cacagtgtac attaaaccag ctaaatgttc
     1621 ctagcttcct gagtccatgg cgttttgact cacaaagtta aagatgattt actttcatgt
     1681 ttcaggtccc cgggttgagt caggaacact aatgacattc agatagccac agcatgtctt
     1741 aatatttgat acgttatggt cggtctttag ctgtggatca ttcccacagc caaaatgtaa
     1801 tgcagaaaag catcaaaaaa gtctcttcag ccagagatgc cagtgactcc agaacagggt
     1861 acagttgcca aatcccggtt gccctccagt gaactgcctt ccccacctgc tgtggaggtt
     1921 gtccagtatc ccggctctta ctgtatctga taaatggttt aattttcttt tagagtggag
     1981 tgttctgccg ttacttagta gggaatgggt tgtaattaca gtcggccgtt gtggcatagc
     2041 tcattgtcta attgtggcgg ttcctctctc agcagtgcat tgctaggatt gggtgcctgt
     2101 gagctgtgat ttttaagaat acgtgtgaca gtcccaatct tgtggtactt acttgtgagg
     2161 atatgcagta gctcgtgaga ggaaatttaa actggagtta ggagtctcag agctccacat
     2221 cggccacagt tagcaccctg gcactgtctg tccagttgct gcttgctttc cttctccctg
     2281 ggggtgagct gttgtggttt ttattctcac acaggataac gaacgagatt gtctctctcc
     2341 cctaatttgc ccacctccct atttgaagaa aacttttgat atatatgcct tactgagtat
     2401 ttacttccct taatatgact caaaataatt tttaaggttt actgacaaca taaaataatt
     2461 cctttcacta tattgtggtt attttataaa tcacaccttt ttatgaatgt ggagattttt
     2521 tttttccttt ggactttgtc tttatttagt tttgtggtgg tgaaatttac ttgctgattt
     2581 tattttccac tgaatgaagt ttgtgcttaa atgaagagtg tgtcttaaac cctttttttt
     2641 ggacaggttg cacttggata aaataggcac cactgtgttg atatgtaatt aaattcataa
     2701 ctattattat ctatgaatgg aaccattctt aaatattgta gctcattcct ttgttgaata
     2761 tctgtctgct gctttgtaaa aacaaaacaa aaaacaaaaa caaaaccatt ggtacgtcac
     2821 gtaaacattt taaaattcta atcattgtcg tccaggctgt cgaagataag cccaggggct
     2881 tacgtgtatc tggagacatt ctctgagaca aaaaatgaaa gcaaaaattg gtgagaagtt
     2941 gatgtgaaaa tgggtagtga ttctgtgctt gttaataaat tgccatcatg gaggctggaa
     3001 ggtgagccgg ttgtgtgagg ataactgttc cgtccacctt gtgctctgtg tgagtttgtt
     3061 agaaggtcct tgttttcttg accttgtaca cagtaatatt catttgtata aaggaaaata
     3121 actgataaat atttataaaa taatgaattt ggaccacagg ctttcttcac cttgtacagt
     3181 agactgaaaa atcatgtcct ataattttag ggcttttttt ttttttcttt ctgtttttca
     3241 aaatgtatgt tctctttatt gcatcaagtg gatttaaaag aaaatgcttt gtgccttttg
     3301 tttgtttgtt tttaaacttg cctctgtgat agtaaagaaa tgtgtttcta gttctgttgt
     3361 cactgttgaa tggcagagga cgctgctggc agggggaagt ggaagggagc acacagagtc
     3421 tcagaatctt gtgaactccc acagaactca gaatccctcc cagcctgctc atgccctccg
     3481 tcatggttgt gcatcgcgag atgcccatat gttgtagcga tacagcggcg gatgcgggct
     3541 tgattgtcag gggctctgtg tatctctgcc acgccccttc ctgtaacttt cccaagtgta
     3601 aacggtactg caagcttatg catagtgttt cccaggtggc acggagttgc cctttgggaa
     3661 gcagcatcgc ggttggaagt gcacacgcat gccttctgta cttggccctg gccaggtgca
     3721 agtttctttt caggctgtgg aaaagccctt ttcaagcttg tcaggaaata atctccctgt
     3781 gtttgggagg gtgtggggtg caaaaaacat taacagtgct tggatgaagg ctgccacctg
     3841 gtctttcaat ggtatttatg accttactgc agttcactat ttaaaattgc cataatcatt
     3901 gtcttggttt tcaaaaatac taatagagtt tataggtttt agagcaatag agtgactttg
     3961 aagtaaaaat ataaccattc tttcttggca tttcaattat tatgattgaa atacttctaa
     4021 ttccaatttt gaaaaaaatg ttgagcatgt ttagggtgtt atagtagcac tgctaatatg
     4081 ccacttgccc actcctgagg cattgggaga gaggtgtaca tctgggctta gcacatgcta
     4141 aatacattaa gggagtatat tgtagtcaga gtaggtatga aaggcacctt gcttcctgaa
     4201 gccgacctca gctccatgat ctatggagga ataaactggt catttggagg tttttaagtc
     4261 taggacgact tcttaccttt aaaatgtaac ttgaaaccta cttgtaactt ttcctgtcac
     4321 tgagcaagca gttaggacag aaacagctct ctgcatcccg gctggcttgc agacagattc
     4381 atgtggtgaa tgccttaaat ctcttggttg gtgaaggact ggaaacaaca ctgagaaggt
     4441 taagcctgag gtctgcagct ttgactctgg gtctccaaat tagccagaaa cagatgcaga
     4501 gatggagttg gctgtgggga tgcgcgtgtt tgggatgctc tcatcattac ttctggattt
     4561 gatcaagccc tctttaggaa ctgtgacgac agaccagaat tttctttgtc caatgaaatg
     4621 tcattttaat gcaaaatatc ttgaacactc actgtgggtg agtaattcgc tgccctatgc
     4681 cagccttcca ggaaggcttt tcctttatta attatgtaaa ctagtggctt gtacatatta
     4741 aatgttttgt ttttgtttct aaatcatcta taaatggctg acatcacagc aggcagtgac
     4801 ctcggggtgt gtggtgaatc atggtggtct accttttcca gagagagaga gaggaggatg
     4861 tgtctgtgat gagcgtggga attggacttg ctggctgatt tatttccact gttttacaaa
     4921 ctaaatgtaa cttactctct aacctgcatg ttagtagtgt gctttgctga gagactacgc
     4981 cagctggtta ccatctgtat gattttttaa gcagaaatat attcttttta tagctatctg
     5041 ttgagctcac gtttagggta gcagaaggaa ttttgacatt tgcagccttt cacaggcagc
     5101 ctgagcaagg tttgttcatt cagtgaggaa ggctgggttc cccggatgga aaaaaagcgc
     5161 tacacacgca ttttagagta ttcaataagg gcttgtctgt cggtaggaaa aaacctgtgg
     5221 gtggaacaga aaggaggctc tgggctttta gattattgtg atttcccttt cagaaaatca
     5281 ttcttagaga gctggatgga gtcagagccc agctgcttta atggcagttg gaccatggcc
     5341 attgagagtc taaaatagga gcagaagccg ctgccctttc agcagcacta aaacggaaat
     5401 cagagatggt agtgaggcca aggactgtcc agtgctatgg gtcttttcta tcacgttggc
     5461 taagctcttt taagcagttt ctctgggtaa cagaattcct ggtaagcacg tagggatggc
     5521 ctgttgagat tgctgtttct cagcagcagg gagcatcaga gccgcctgcc atctcgactg
     5581 tcgtgttatc agttggatat cctcatcaga gcagccatcc tccagacaaa gactcagttg
     5641 tgtatatggt tagttcattc agaatgtccc aagaaagcag aattcagcac tgaactcaga
     5701 atttcagtta aacaacaaaa tctccccact tttgggcaga gtggaagaca ataatggcca
     5761 aggtactcag gaacccaggt ttcctctccc ttcctgccta acggtggtaa ctgaatggta
     5821 actgaagaaa attaaagtgc tgcttttgtg agtgaggctt catgttctat gctgagaaca
     5881 ggtaacaggg gctgtgtggc taggggttta atttggtgcc tttatgggta gacttctgaa
     5941 gcaagagtat aatttcttcc cagatactta aaaaacacca cgagaacagg tggggtatgt
     6001 ttgccacaaa gaatgaaaaa gatagcagag atgaagaaaa agaggacata aaatgtctcc
     6061 ccttccaggt acttttagtt gtagttggcc tgcctagggc tttggtgtta gtgtagcgtt
     6121 tgtttactct gcttccgtgt gctctgcata tgtacatgtt tactatgcat acctgttctc
     6181 tatgtatata tgatatggta tctaatggac ttgactcttg attatcagcc gggtggcaac
     6241 cctcattagt ctgttgcttt gtgtggattt ggcgtgccca tggcccacat ggaaagccac
     6301 ttccccacct ttcccctcca gggcatctca gccctgagaa agccctcaca gtagatgata
     6361 tttcacttcc ctttcaccag gggacttcga gccagaaaga ctggtttcca gaatgctggc
     6421 tattacttcg gggttgaggt ttctgggtcg gcccggccct cttttggctg ggaggcagct
     6481 ttgggagcag tgtgctatga actccatctg ggagatactt gatcttgctg gagcagagct
     6541 ttgcccttgc ttcacttttc tggagtgttg caaggcttgt gattccatgt agagtagaat
     6601 attctcggta gtttgaatgt gggttttgca ttgtctgtgt tcttgtcacc ggattctaga
     6661 aaccttgatc tttcaactgg atttatgttt gtgtctgctg ctatagactc caaaagttaa
     6721 agcagtaggt tctagttttc aattgtttaa ttctttattg ataaatattt attgtaataa
     6781 aaaataaata atttttaaat cttttt
//
