LOCUS       NM_172710               4532 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus sel-1 suppressor of lin-12-like 3 (C. elegans)
            (Sel1l3), mRNA.
ACCESSION   NM_172710
VERSION     NM_172710.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4532)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4532)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4532)
  AUTHORS   Whiley,P.A.F., O'Donnell,L., Moody,S.C., Handelsman,D.J.,
            Young,J.C., Richards,E.A., Almstrup,K., Western,P.S. and
            Loveland,K.L.
  TITLE     Activin A Determines Steroid Levels and Composition in the Fetal
            Testis
  JOURNAL   Endocrinology 161 (7) (2020)
   PUBMED   32274496
REFERENCE   4  (bases 1 to 4532)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   5  (bases 1 to 4532)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   6  (bases 1 to 4532)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   7  (bases 1 to 4532)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   8  (bases 1 to 4532)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK122362.1, BC094607.1 and BP769904.1.
            
            On Aug 3, 2007 this sequence version replaced NM_172710.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122362.1, AK030487.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1382              AK122362.1         1-1382
            1383-2447           BC094607.1         928-1992
            2448-4510           AK122362.1         2448-4510
            4511-4532           BP769904.1         1-22                c
FEATURES             Location/Qualifiers
     source          1..4532
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 28.96 cM"
     gene            1..4532
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /note="sel-1 suppressor of lin-12-like 3 (C. elegans)"
                     /db_xref="GeneID:231238"
                     /db_xref="MGI:MGI:1916941"
     exon            1..323
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..3560
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /note="sel-1L3; suppressor of lin-12-like protein 3"
                     /codon_start=1
                     /product="protein sel-1 homolog 3"
                     /protein_id="NP_766298.2"
                     /db_xref="CCDS:CCDS51501.1"
                     /db_xref="GeneID:231238"
                     /db_xref="MGI:MGI:1916941"
                     /translation="MQWRGAGLWWPRRRQQQQQQQPPPPAFGPPAAAMVPPSRGVSPG
                     LGGRPTSALLFLCYLNFVPSLGRQTSLTTSVLPRTEQSTTYADFIYFTAFEGSVRNVS
                     EVSVEYLCSQPCVVHLEAVVSSEFRSSIPVYKKRWRNEKHLHTSRTQTVHVKFPSIMV
                     YRDDYLIRHPISVSTVILRAWITHWHSGGGLNVRGEENLLHAVAKNYTLLQTVPPFER
                     PFKDHQVCLEWNMDYLWSLWANRIPQCPLESDAVALLSFPYASSGENTGIVKKLQNFQ
                     NRELEATRSQRVDYPMVTISLWLYLLHYCEASLCGILYFVDSNEMYGTPSVFLTEDGS
                     LHIQMHLVKGEDLAVKTKFTIPLKEWCRLDISFNGGQIVVTASIGWDLKSYHNQTISF
                     HEDFYYNDTAGYFIIGGSRYVAGIEGFFGPVKYYRLRSLHPAQVLNPFLEKELAEQIK
                     LYYERCTEVQDIISSYAATVQVGGERRETCDFHNSYLDLKRKYGRAEVCRGLPWEKEL
                     RDRHPSLFQSLLQMDLLTVPWNQNDSVLEIGARIFEKAVKRLSGVDGLHQISSAIPFL
                     MDSSCCGYHKASYYLTVFYETGLNGPRDQLQGMLYSLVGGQGSERLSSMNLGYKHYQG
                     VDSYPLDWELSYAYYSNIATKTPLDQHTLQGDQAYVETIRLKDDEILKVQTKEDGDVF
                     MWLKHEATRGNAAAQQRLAQMLFWGQQGVAKNPEAAIEWYAKGALETEDPALIYDYAI
                     VLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKFRKNYAKAAKYWLKAEEM
                     GNPDASYNLGVLYLDGIFPGVPGRNLTLAGEYFHKAAQGGHIEGTLWCSLYYITGNLE
                     TFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAYLEGLWHEALLYYVLAAETGIEVSQ
                     TNLAHICEERPDLAGRYLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYGHQNQSQD
                     LELSVQMYAQAALDGDSQGFFNLAALIEEGAVIPHHILEFLEIDPSLHSSNTSILQEL
                     YERCWSLSNEESLSPCSLAWLYLHLRLLWGAVLHSALIYFLGTFLLSVVIAWMVLYLQ
                     YISASGSSPAPAWVSADPTSSTPSPAVPPAADASDHDPPMMANGPEPRG"
     exon            324..894
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1021
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1143
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1259
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1318
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1451
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1584
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1725
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1937
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2117
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2118..2237
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2378
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2379..2441
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2442..2618
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2746
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2830
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2921
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            2922..3006
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            3007..3116
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            3117..3244
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            3245..3347
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3420
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     exon            3421..4512
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4488..4493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /note="hexamer: AATAAA"
     polyA_site      4512
                     /gene="Sel1l3"
                     /gene_synonym="2310045A20Rik; mKIAA0746"
                     /note="major polyA site"
ORIGIN      
        1 tggcggcggc gggtccggtg gcagcggcag gtggccccgc gcgcggcggg ccgccggccg
       61 ggggcgggag ggaaggtggc gcctcgggcg ggggccggtc cctgcaccag gtgacctgtt
      121 ccggccggga tccgggcggc ctcgccatgc agtggcgcgg cgcggggctt tggtggccac
      181 ggcggcgaca gcagcagcag cagcagcagc ccccgccgcc cgctttcggt cccccggccg
      241 cagccatggt ccccccgagc cgcggtgtct ccccgggcct cggcggccgc cctaccagcg
      301 cattgctctt tctctgctac ctgaattttg tgccatcgtt gggcaggcag acttccctga
      361 cgacatcagt gctgcccagg acagaacaga gcacaacgta tgcagacttt atttatttta
      421 ctgcctttga agggagcgtg cgcaatgtct ctgaagtctc cgtggagtat ttatgctctc
      481 agccttgtgt tgtccatttg gaggcggttg tctcctccga gttcagaagc agcatccccg
      541 tgtacaagaa gaggtggagg aatgagaagc atcttcacac cagcaggacg cagacagtgc
      601 acgtgaagtt cccgagcatc atggtgtaca gggatgacta tttgatcaga caccccatct
      661 cggtgtccac ggtgattctc cgagcctgga ttactcactg gcacagcggc gggggcttga
      721 acgtccgagg ggaggagaat ttgctgcacg cagtagcgaa gaattacacc ctgctgcaga
      781 cggtcccgcc ttttgaacgg cctttcaaag atcatcaggt gtgcctggag tggaacatgg
      841 actatctctg gagcctctgg gccaatagga tcccacagtg tcctctggaa agtgatgcag
      901 ttgccctcct cagcttcccc tatgcttcca gcggagaaaa cacaggcatc gtgaagaagc
      961 tccaaaattt ccagaacaga gagctagagg ccactcgaag ccagcgcgtg gactacccca
     1021 tggtcaccat ttcactgtgg ctttatttac tccattattg cgaggccagc ctctgtggaa
     1081 ttctgtactt tgttgattct aatgagatgt acggcacgcc ttctgtgttt cttacggaag
     1141 acggcagttt gcacattcaa atgcatctcg tcaaaggaga agacctggct gtaaaaacca
     1201 agttcaccat cccattgaag gagtggtgcc gactggatat ctcgttcaat ggaggccaga
     1261 tagtggtcac tgccagcatt ggatgggact tgaaaagcta ccataatcag accattagct
     1321 tccatgaaga cttctattat aacgacacag ctggctactt cattattgga gggagcaggt
     1381 acgtggccgg catcgaaggg ttttttggac cggtgaaata ctatcgcctc cgcagcctac
     1441 acccggcaca ggttcttaat cccttccttg agaaggaact ggctgaacaa atcaagctat
     1501 actatgagcg gtgtactgag gtccaggata taatatcctc gtatgctgca acagtccagg
     1561 ttgggggtga gaggcgagag acatgtgact tccataactc ctacctggac ctcaagcgca
     1621 agtatgggag agccgaggtg tgcagaggct tgccctggga gaaggaactg agagacaggc
     1681 accccagctt gttccagagc ctgctgcaaa tggacctgct gaccgtgcca tggaaccaaa
     1741 atgactccgt attagaaatc ggtgcaagga tatttgagaa ggctgtaaag agactctctg
     1801 gcgttgatgg ccttcaccaa attagctctg ccatcccctt tctgatggat tccagctgct
     1861 gtggatacca taaagcatcc tactacctca ccgtcttcta tgaaactgga ttaaatggac
     1921 ctcgggatca gctgcagggc atgctataca gtctggttgg aggccagggc agtgagagac
     1981 tgtcatcaat gaatcttggg tacaaacact accagggtgt tgacagctac ccactggact
     2041 gggaactgtc ctatgcctac tacagcaaca ttgctacaaa gacacccctt gatcagcaca
     2101 cactgcaggg agaccaggca tatgttgaaa ctattaggct caaagatgat gaaatactca
     2161 aagtccaaac caaagaagat ggcgatgtct ttatgtggct gaagcacgaa gccacccgtg
     2221 gcaacgcagc agcacagcaa cgattggctc agatgctctt ctggggacag caaggggtgg
     2281 ccaagaaccc tgaggccgct atcgagtggt acgcgaaggg ggccctggag acggaggatc
     2341 cggcgctgat atatgactac gccattgtgc tattcaaggg tcaaggagtt aaaaagaaca
     2401 gacggctcgc cttagagctc atgaagaaag ctgcttccaa gggattgcat caggctgtca
     2461 atggcctggg atggtattac cacaaattca ggaaaaatta tgccaaagca gccaagtact
     2521 ggttaaaggc agaagaaatg gggaacccag atgcgtctta caatcttggg gtcctgtatt
     2581 tggatggcat tttcccggga gttcctggaa ggaatctgac actggctggt gaatacttcc
     2641 ataaagctgc acaaggtgga cacatcgaag ggacattgtg gtgttccctt tactatatca
     2701 ccggcaacct ggagaccttc cctagagatc cagagaaagc tgttgtatgg gcaaagcatg
     2761 tggccgaaaa aaacggatac ctgggacacg tcatccgcaa aggtctcaac gcctacctgg
     2821 agggcctgtg gcacgaagct ttgctgtatt atgttttagc agcagaaact ggaattgaag
     2881 tgtcacagac aaatttagca cacatctgcg aggagaggcc agacctggct gggagatact
     2941 tgggcgttaa ttgtgtttgg cgatactata atttctctgt ttttcaaatc gatgctcctt
     3001 catttgcgta tctgaaaatg ggagaccttt actactatgg ccatcaaaac cagtcccaag
     3061 atctggagct gtctgtgcag atgtacgccc aagcagccct ggatggagac tcccagggat
     3121 ttttcaacct cgccgcactg atagaggaag gtgctgtcat cccacaccac atcctggagt
     3181 tcttggaaat cgacccttca ctccattcca gtaacacctc catactccag gagctctacg
     3241 aaaggtgctg gagtctcagt aatgaggagt cccttagccc ctgctccttg gcctggcttt
     3301 accttcatct tcggcttctc tggggtgccg ttctgcactc tgccctgatc tacttcctgg
     3361 gaaccttcct gctttccgtg gtgatcgcct ggatggtgct ttatctccag tatatctcag
     3421 ccagtggctc ctctccagca ccagcctggg tctcggcaga ccccacctca tccaccccaa
     3481 gtccagctgt gcctccggct gcagatgcct ccgaccacga cccacccatg atggctaacg
     3541 gccctgagcc tcgtgggtga actgtgcgcc cctggtctct ccagctgaga gacggtcctt
     3601 ttagcagctg gtttgggaag gctggtgcca ggcgttacac tgataaatac cttaaaagtc
     3661 ttgtgaactg gatgccaact ttgcacttgg tgtctttttg tttatgttta aacaagaaca
     3721 taggcagagc agactgtagt tatccaacag attcaagggt tacccggaaa acaggggaat
     3781 cgggggaggc gagctgaggc tttggacttt ccttcctggt gactgttctg ggaaccgcag
     3841 tccatatgtg gagcgtccat atagagtcat ttttaaaagt tttagtctgt cttcatcccc
     3901 ttttaccaga gaataggaac ttatctccaa ggctgactga cgatgcttca gtacctctgt
     3961 ttgccaccgc atcctgctcc gcaaaagccc agctggttgc tctctgagtc ccaaatccag
     4021 cagctagaag gagccttgag acaaacactc cacacacagg gaaggcgata acattgtaca
     4081 ttggtttaca ttttttcccc ctgtggattt ttctagaggt catagtgctt ccaaatcatt
     4141 tgatgacatt attgggtatc gtttatgttt ccatcataac acatgcaata acatctagga
     4201 aatctttacc gtttaagtgt agtctgcttc cccatgagtc accattagaa tagactggca
     4261 gcaatggaat acgcagacaa aaaacaagct gttagttcat aggttcatca ccacccctta
     4321 tgcctgcctg tgtctgtata ggtgtgtgtg tgtgagagag agtgtgtgta agaggacaaa
     4381 aaaagaacag agtgtctgtg cactgtatgc tgctacagta gtaaataaat cagtaacgca
     4441 atactgtggg ttcaaactat ctttgcacta ctttatttac agtagtaaat aaaattattt
     4501 ttctacagtt gaaaaaaaaa aaaaaaaaaa aa
//
