LOCUS       NM_001419039            2518 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus secreted and transmembrane 1B (Sectm1b), transcript
            variant 4, mRNA.
ACCESSION   NM_001419039
VERSION     NM_001419039.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2518)
  AUTHORS   Mu,X., Wang,P., Wang,X., Li,Y., Zhao,H., Li,Q., Essandoh,K.,
            Deng,S., Peng,T. and Fan,G.C.
  TITLE     Identification of a Novel Antisepsis Pathway: Sectm1a Enhances
            Macrophage Phagocytosis of Bacteria through Activating GITR
  JOURNAL   J Immunol 205 (6), 1633-1643 (2020)
   PUBMED   32769121
  REMARK    GeneRIF: Identification of a Novel Antisepsis Pathway: Sectm1a
            Enhances Macrophage Phagocytosis of Bacteria through Activating
            GITR.
REFERENCE   2  (bases 1 to 2518)
  AUTHORS   Lyman,S.D., Escobar,S., Rousseau,A.M., Armstrong,A. and
            Fanslow,W.C.
  TITLE     Identification of CD7 as a cognate of the human K12 (SECTM1)
            protein
  JOURNAL   J Biol Chem 275 (5), 3431-3437 (2000)
   PUBMED   10652336
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662887.13.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020159.1, SRR5189685.123495.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-356               AL662887.13        96337-96692         c
            357-520             AL662887.13        89345-89508         c
            521-829             AL662887.13        88806-89114         c
            830-2518            AL662887.13        86563-88251         c
FEATURES             Location/Qualifiers
     source          1..2518
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 84.87 cM"
     gene            1..2518
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /note="secreted and transmembrane 1B"
                     /db_xref="GeneID:58210"
                     /db_xref="MGI:MGI:1929083"
     exon            1..356
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /inference="alignment:Splign:2.1.0"
     exon            357..520
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /inference="alignment:Splign:2.1.0"
     CDS             427..1065
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /note="secreted and transmembrane protein 1b"
                     /codon_start=1
                     /product="secreted and transmembrane protein 1b precursor"
                     /protein_id="NP_001405968.1"
                     /db_xref="GeneID:58210"
                     /db_xref="MGI:MGI:1929083"
                     /translation="MLAYSVTSSGLFPRMLWALLLLAASLNAYNHVWDKPCCTEHEVS
                     VNRGSRVVMACNISNNLRDVTIELVTSKKTSIIFNQTPPGNYSKDSWQLHIQGGQAQL
                     VITDAQGKHSGEYWWKLRGFQAEFKNFNLIVNAADRQKTEDLPVTKVPDKPPTAVRTE
                     VIIIIAIATTIIITGIGVFVWYKQFPVAPQIQMSVPCLIHGSPGIPYLTLPP"
     exon            521..829
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..2518
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1411
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /note="major polyA site"
     regulatory      2456..2461
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /note="hexamer: AGTAAA"
     regulatory      2484..2489
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /note="hexamer: AATAAA"
     polyA_site      2485
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
     regulatory      2488..2493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
                     /note="hexamer: AATATA"
     polyA_site      2510
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
     polyA_site      2518
                     /gene="Sectm1b"
                     /gene_synonym="1810003C24Rik; K12; Sectm1"
ORIGIN      
        1 agagaagcag gtaagaagct ggagcacaca tgcaggtgag aactggaggg gaggtggcac
       61 ccagagtgtt ggggctctaa agcatgtggg gtgagaccct caggcagggt gtccctggct
      121 gcagcctctc tgggaccctc tgtttattgg atgcctgtgt ctcagtgatt tgtccagagt
      181 aaaggtgagg ctgaggagtg tccaggcacc ctggacatca ggagcagagt ggatctgtgt
      241 ctctccaggt gcctcccacc aagctccagg aggagcaggt gcagcagctg ggttcttcgg
      301 tgtgaactga atgggaagaa gagaacagag cattctttct tgtcatctga tcatgatgtc
      361 caacaacaac aacaaaagac agtgaccaga acaattgtct cctgaggccc atcctaggaa
      421 tgagccatgc tggcctactc tgtaacatcc tctggcctgt ttcccagaat gctctgggcc
      481 ctccttctac tggcagcctc cctgaatgcc tataaccatg tctgggacaa accttgttgc
      541 actgagcatg aagtatctgt aaacagaggc agccgcgtgg tgatggcctg taatatctcc
      601 aacaatctca gagacgtcac cattgagttg gttaccagta aaaagactag catcatcttc
      661 aatcaaacgc ctccaggaaa ctactctaag gattcatggc agcttcatat tcaaggaggc
      721 caggcccagc tggtgatcac agatgctcag ggcaaacact caggggagta ctggtggaag
      781 ctgcgtggat tccaggcaga gttcaaaaac ttcaacctga ttgttaatgc cgcagacaga
      841 cagaagacag aggacttgcc agtcactaag gtccctgata agcccccaac tgcagtgcgg
      901 acagaagtta tcatcatcat cgccattgct accaccatca tcatcacagg aatcggtgta
      961 ttcgtttggt acaagcaatt ccctgtagct ccacagatac aaatgtcagt accttgtctg
     1021 attcatgggt ctcctggtat cccctacctg acactgcccc cctaaagtct cccaattcct
     1081 gcctcaaaag atactcaagg gaccttagta gctccaaaca tcaggctaca gagaacctca
     1141 cctggctatg gctgacaatc caagccctga ttgacaagat cacaggaact ctctgtctcc
     1201 caagccctca ttttgacctt gggacaggta gacgtcagaa tggggtctgt actcctcagg
     1261 ttcctcccaa gactccagga caatttgcac tgaggacggc actgtggttt ttaactgagg
     1321 ataccctgga agttgtctga acccctcctg tactcaaaac gtagactctg ttggggcttg
     1381 ggggacatca aagtatttca gagtatccca agtgtgcgtg gtgtacctgc ttatttgtgt
     1441 aagctctttg tgctgcagca tctgtgcctc acacaggccc aagccagggt ctcaggcagc
     1501 ttttccctct cctctcccct tccttccaca tgcctttcct ttcttcctcc ctctctgact
     1561 ccctctttct ccggatgagg aggctcacag ccttatgggc gattggaacc tcaggggtag
     1621 ccccctgaag aatgacctcc cattcttgga ggtcccagaa caaggccaac accatggact
     1681 tggagtccct gtaaccctac aagcatccat ggacctatca ccacccactg gcaacagcaa
     1741 ggaagaacct tgtttgtatt tgctaggcac agtagcccat gtctcacgtc tggggagaag
     1801 cacggaatcc catcatgtcc tgcgcagaga cagggacagg cctgatgatc cgggcctctc
     1861 tggctctcaa taacacactt tcccctgtga tcgatacctg cttactcaga tcctcgattt
     1921 ttcccaaaat cagcacggcc ctcgaccctc agggtttatc caccctgcct tttaaaggag
     1981 gcctgaggtc cttccctgct aaactcactt cacttcccta tggtctccgg tgccagcagg
     2041 ggcttgtggg agattcagta ccagctttgc tcctggcaca tagatcgtgt cttctgactc
     2101 acagcaatag ttagtttccc aggtcttgct gtcagggtcc acggtcttat gtgagaaata
     2161 gaggtccaaa atgatgcatc accacattcc taccactagg tggtggtgtg ggcctgtctg
     2221 cggggaaacc tcagggacaa ggagctcact gaggggccga ggcctgctag tgggcaccgc
     2281 ttttgtggga ggatagctgg accttcaaat tccccatgaa cctctttgta gaccctctcc
     2341 ctgactctct acttacctcc gccctcacct gctgttcctc tcgggctagt ttatcttctt
     2401 tactctaata ccaacttgaa caatttagtc ttaaatacac tgtaattcat tcttcagtaa
     2461 aatacttcat gatgcaaatc ttaaataaat atagtaagtc aatgattcta taaagcca
//
