LOCUS       NM_153055               6058 bp    mRNA    linear   ROD 16-JUN-2024
DEFINITION  Mus musculus SEC63 homolog, protein translocation regulator
            (Sec63), transcript variant 1, mRNA.
ACCESSION   NM_153055
VERSION     NM_153055.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6058)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6058)
  AUTHORS   Ishikawa,Y., Fedeles,S., Marlier,A., Zhang,C., Gallagher,A.R.,
            Lee,A.H. and Somlo,S.
  TITLE     Spliced XBP1 Rescues Renal Interstitial Inflammation Due to Loss of
            Sec63 in Collecting Ducts
  JOURNAL   J Am Soc Nephrol 30 (3), 443-459 (2019)
   PUBMED   30745418
REFERENCE   3  (bases 1 to 6058)
  AUTHORS   Hassan,H., Tian,X., Inoue,K., Chai,N., Liu,C., Soda,K., Moeckel,G.,
            Tufro,A., Lee,A.H., Somlo,S., Fedeles,S. and Ishibe,S.
  TITLE     Essential Role of X-Box Binding Protein-1 during Endoplasmic
            Reticulum Stress in Podocytes
  JOURNAL   J Am Soc Nephrol 27 (4), 1055-1065 (2016)
   PUBMED   26303067
REFERENCE   4  (bases 1 to 6058)
  AUTHORS   Fedeles,S.V., So,J.S., Shrikhande,A., Lee,S.H., Gallagher,A.R.,
            Barkauskas,C.E., Somlo,S. and Lee,A.H.
  TITLE     Sec63 and Xbp1 regulate IRE1alpha activity and polycystic disease
            severity
  JOURNAL   J Clin Invest 125 (5), 1955-1967 (2015)
   PUBMED   25844898
  REMARK    GeneRIF: SEC63 function regulates IRE1alpha/XBP1 activation. SEC63
            and XBP1 are required for GPS cleavage and maturation of PC1,
            protecting against polycystic disease.
REFERENCE   5  (bases 1 to 6058)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 6058)
  AUTHORS   Su,R.W., Sun,Z.G., Zhao,Y.C., Chen,Q.J., Yang,Z.M., Li,R.S. and
            Wang,J.
  TITLE     The uterine expression of SEC63 gene is up-regulated at
            implantation sites in association with the decidualization during
            the early pregnancy in mice
  JOURNAL   Reprod Biol Endocrinol 7, 12 (2009)
   PUBMED   19208265
  REMARK    GeneRIF: SEC63 gene expression is up-regulated and predominantly
            localized in mouse decidual cells during days 5-8 of pregnancy.
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6058)
  AUTHORS   Pierreux,C.E., Poll,A.V., Kemp,C.R., Clotman,F., Maestro,M.A.,
            Cordi,S., Ferrer,J., Leyns,L., Rousseau,G.G. and Lemaigre,F.P.
  TITLE     The transcription factor hepatocyte nuclear factor-6 controls the
            development of pancreatic ducts in the mouse
  JOURNAL   Gastroenterology 130 (2), 532-541 (2006)
   PUBMED   16472605
REFERENCE   8  (bases 1 to 6058)
  AUTHORS   Chalhoub,N., Benachenhou,N., Rajapurohitam,V., Pata,M., Ferron,M.,
            Frattini,A., Villa,A. and Vacher,J.
  TITLE     Grey-lethal mutation induces severe malignant autosomal recessive
            osteopetrosis in mouse and human
  JOURNAL   Nat Med 9 (4), 399-406 (2003)
   PUBMED   12627228
REFERENCE   9  (bases 1 to 6058)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 6058)
  AUTHORS   Chalhoub,N., Benachenhou,N. and Vacher,J.
  TITLE     Physical and transcriptional map of the mouse Chromosome 10
            proximal region syntenic to human 6q16-q21
  JOURNAL   Mamm Genome 12 (12), 887-892 (2001)
   PUBMED   11707774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC059816.1, AY024346.1 and BF472596.1.
            
            On Oct 31, 2007 this sequence version replaced NM_153055.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059816.1, SRR1660815.259420.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-412               BC059816.1         1-412
            413-2761            AY024346.1         210-2558
            2762-6029           BC059816.1         2761-6028
            6030-6058           BF472596.1         679-707
FEATURES             Location/Qualifiers
     source          1..6058
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 22.89 cM"
     gene            1..6058
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="SEC63 homolog, protein translocation regulator"
                     /db_xref="GeneID:140740"
                     /db_xref="MGI:MGI:2155302"
     exon            1..393
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..2552
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     translocation protein SEC63 homolog; SEC63-like; dnaJ
                     homolog subfamily C member 23"
                     /codon_start=1
                     /product="translocation protein SEC63 homolog isoform 1"
                     /protein_id="NP_694695.3"
                     /db_xref="CCDS:CCDS23815.1"
                     /db_xref="GeneID:140740"
                     /db_xref="MGI:MGI:2155302"
                     /translation="MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQI
                     RLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQE
                     YNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKN
                     WEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRY
                     SGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDSTSRPTDNILIPQ
                     LIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQ
                     EMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEE
                     DNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDEKYEEVMAVLGSFPYVTMDIK
                     SQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPTEDGQSDANKIK
                     AKGGWQQKNKGPKKMPKSKKKKPLKKKPTTVPLPQAKQQKQKQANGVVGSEAAIKEEE
                     DDISDKGSDSEEEETNRDSQSEKEDGSDRESDREQDEKQSKDDEAEWQELQQSIQRKE
                     RALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELK
                     FPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQE
                     DSEGFEDSFEEEEEEEEGGD"
     exon            394..493
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            494..608
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            609..721
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            722..783
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            784..842
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            843..893
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            894..1002
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1097
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1230
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1323
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1478
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1626
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1709
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1769
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1943
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1944..2102
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2204
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2303
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2304..2408
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2409..6032
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2774..2779
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2800
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="major polyA site"
     regulatory      3886..3891
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3910
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="major polyA site"
     regulatory      6005..6010
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6029
                     /gene="Sec63"
                     /gene_synonym="5730478J10Rik"
ORIGIN      
        1 gtggaggaga cggccgggga gggaacagcc gcgtggggcg ggaactagct cctctcgcga
       61 gagttggcga cggccgcggc ggcggcggcg gcgtgtccgt gagagcggcg tgggggcggg
      121 gaggagagcg gcggcggcgg cggcggcggc ggcggtagcg gcgtccgagc tacgccacac
      181 ggggccgggg cgctgggagc cgggagccgg agcgcagcgc ggggtcgtgg cgacggcggt
      241 gaggggagcg cggcggagga ggcggagcca tggcgggcca gcagttccag tacgatgaca
      301 gcgggaacac cttcttctac ttcctcacct ccttcgtggg gctcatcgtg atccccgcca
      361 cctactacct ctggccgcga gaccagaacg cggagcaaat tcgattaaag aatatcagaa
      421 aagtatatgg aagatgtatg tggtatcgtt tacggttatt aaaaccccag ccaaatatta
      481 ttcctacagt aaagaaaata gttctgcttg caggatgggc actgttctta tttcttgcat
      541 acaaagtttc caaaacagac cgagaatatc aagagtacaa tccttatgaa gtactaaatt
      601 tggatcctgg agcaacagtg gcagaaatta agaaacagta tcgcttgttg tcacttaaat
      661 atcatccaga taaaggaggt gatgaagtca tgttcatgag gatagcaaaa gcatatgcag
      721 ctttaacaga tgaagagtct cggaaaaatt gggaagaatt tggaaatcca gatgggcctc
      781 aagctacaag ctttggaatt gctttgccag cttggatagt tgaccagaaa aattcaattc
      841 tggttttact tgtgtatgga ttggctttta tggttattct tcctgttgtg gtgggctctt
      901 ggtggtatcg gtcaatacga tatagtggag accagattct aatacgtaca acacagattt
      961 atacatactt tgtttataaa actcgaaata tggatatgaa acgtctcatc atggttttag
     1021 ctggagcttc tgaatttgac cctcagtata ataaagattc cacaagcagg ccaacagata
     1081 atattttaat accacagcta atcagggaaa ttggcagcat aaatttaaag aagaatgaac
     1141 ctccactcac ctgtccatac agcctgaagg ccagagttct tttactgtct catcttgcta
     1201 gaatgaaaat tcctgagaca ctggaagaag atcaacagtt catgctgaaa aaatgtcctg
     1261 ctctgcttca agaaatggtt aatgtaatct gccagctaat aataatggcc cggagccgtg
     1321 aagaaaggga gtttcgtgct ccaactttgg catccttaga aaactgtatg aagctttccc
     1381 agatggctgt tcaggggctc cagcagttta agtctcccct tctgcagctc cctcatattg
     1441 aagaggacaa tcttaggaga gtttcgaatc ataaaaagta caaaattaaa actatccagg
     1501 atttggttag tttaaaagaa tcagatcgtc atagtctgct acacttcctt gaagatgaaa
     1561 agtatgaaga ggtcatggcg gtccttggga gtttcccgta tgtgaccatg gacataaaat
     1621 cacaggtctt ggatgatgaa gatagcaaca acatcacagt aggatcccta gttacagtgt
     1681 tggttaagtt gacgaggcag accatggctg aagtgtttga aaaggagcag tccatctgcg
     1741 ccgctgagga gcagcccaca gaagacgggc agagtgatgc caacaagatc aaggcaaaag
     1801 gaggatggca gcagaagaac aaaggaccca agaaaatgcc caaatccaaa aaaaagaagc
     1861 ctttaaaaaa gaaacccaca actgtaccct tacctcaggc aaagcagcag aagcaaaagc
     1921 aagcaaatgg agttgttggg agtgaagctg caataaagga ggaagaagac gacatttctg
     1981 acaagggcag tgattctgaa gaggaagaaa ccaatagaga ttctcagagt gagaaagaag
     2041 atggtagtga cagggagtct gatagagagc aagatgagaa acaaagcaaa gatgatgaag
     2101 cagagtggca agagttacaa cagagtatac agaggaaaga gagagctctt ctggagacca
     2161 agtcaaagat aacacaccct gtctatagtc tctactttcc tgaggaaaaa caagagtggt
     2221 ggtggcttta tattgcagat aggaaagaac aaacattaat atccatgcca tatcatgtgt
     2281 gcacactgaa ggatacagaa gaggtagaac tgaagtttcc cgcacccggc aagcctggaa
     2341 attatcagta tacagtgttc ctgagatcag actcctatat gggcttggat cagattaaac
     2401 cactgaagtt ggaagttcat gaggccaagc ctgtgccaga aaaccaccca cagtgggaca
     2461 cagcgataga aggtgacgaa gaccaggaag acagtgaagg atttgaagac agctttgagg
     2521 aagaggagga ggaagaggaa ggtggagact aacccgagtg agtggactac agcgtttgca
     2581 catccttgca aacattgctg ctctgtgaga ggtcataaag cagcagcagt gagggctgat
     2641 atggagggaa gggttgccga ctttactaga aacggatgca aaaaagaggc cgctggtgcc
     2701 agggtacaat ctgaaaaggg tttttaaagc ctttcaggta tggggtggtg cgtttatctc
     2761 atctgcaaat gataataaat cctttgatgt tccaactgtc cagaagtgtg ggctgtgcat
     2821 tacctgatag attatgctct cagtaaaagt caaggcacat gaaaacaatc tataaatgag
     2881 gagctcttct ttgttcagct ttagttttag taaacattaa aatatgataa gcatcacaca
     2941 tgttttaagt aatgtctgct caagttttta atctgttagt aagctctatt attcatttat
     3001 caatatttta caaatggtaa gattgtaaca gttccatatg taagttgaaa ccataatttt
     3061 catctatctt ggccataact tagcattctc acacattcca cataatacag agggctacat
     3121 tttagaattt tccattctta attgcccaga gttagcagac gttataaaag tggcttttat
     3181 tggcttacag cctcttaaag cctctggtgg tgtcagtgca ggatcgaatt aatccgataa
     3241 gcttcagggc caaaagttac tccgggacca cacgttctct gacgctcggt tgatgtcatt
     3301 cagccttttg gaaaaggttc actagaaaag ctgcactaca ttcgtagttt aacctacctg
     3361 actctgtccg aagccttctg aagacagtaa ctacagcata caaaggaggc acttttgtat
     3421 tcatttggac tcctgttaat aaaatagaag tttgactcat tttatgtttg taatcgtgtg
     3481 tgtcttttta ctcctagaga aagggcataa atagggtaat gttttatttt tcaactctaa
     3541 agtttaatat tgtacctcac tgtggaagtg actgctatct ctgtctactc ttggaaagcc
     3601 caggaggaag aactcttctc tctcatttag tacaacctaa aagatagtgc tcaacacaga
     3661 gtagaaatgt gtgtgtgatg agtcactgag gtcagaggaa tatttttatt actagacata
     3721 gaggacacac acgtctacag tactataaga ctgactgcaa taatcctatc aaactctcca
     3781 taggccaaag tactgttgca atactaactt atcacctgtt tatttaaaag gttgctactc
     3841 ttcctgcaga attatcgctg gtattttgtt actacagtag ttggaaataa aatttaaaaa
     3901 ttaccaaaaa tgaatttttt gttattgttc taaatttaag atgtaacatg taatagttgt
     3961 tctcactgga accctgcttc cttcctctgc aggcccgggg gtgtggcttt gccttcagat
     4021 cgagactggc tgggaagctc cagggttggc tggcgctgtt agacgcaggc gggagggagg
     4081 gagggaggga gtcagctgtg tcaggtgagc agagatgaac agccagagct gtgctggtca
     4141 catttcctag ttttcctgag ggagccaggc tcaaggaccg cttctctagt ggctctttgc
     4201 cctctgaaag gtatacagac tgttcaaaca actggcttct ctggcttgag agtctctggt
     4261 gaggatttta caccctgata acagcaccat gcttacaaaa cagcatgtct tccatgattg
     4321 gaaattccaa caacttgatt ctgtttgcct atgttgtgat gtgtagcaac atctcaacct
     4381 aaaggaccag ttttcctctt aacaagtgct ttggggaaag actccagcta gggtgctcgt
     4441 ctctctactc agtcacttaa ctccacatcc ctatttttct ctggattaat aatttgtctg
     4501 agtttgcatt tagttgaagg gagatacaga gtgaaattga ttatgaaatt aagtagttta
     4561 cattgtgtaa aagttttaat ctctagatct gcagaatgtc tgtcaaaata gagctttcca
     4621 caaggggtct tcctgctagt ggaaagtgtg gcaggtgcga aggctgacat cgggccacct
     4681 gactgaggtc tcagacccaa aagcagatgt tcgcagtctc taaactgttg ggatttttga
     4741 gaagactcga gacattgaat taagattctg tgtgtggagc aatctcgttc tttgctctgc
     4801 ctttcccagc atgccctagg ggtggagaag aacaggctgt tgagtggtac tgtcctgctg
     4861 tgctgggacg ttcgggcctg tccgacacca gttcctgcca tgtggaatga ggcagtgtac
     4921 tgaggctttc tttgtgtgac ttgatttgtg ttttgttttt gagactcact atatagcctt
     4981 ggctggcctt gacccacagt gtagcctagg atgtggacct tgtaatcctc ctctggcctc
     5041 cgtctccgga gtaataggat tacaagcaag agccaccacg cctggtgtta acgtatctgc
     5101 tacatgtatt caggtatccg ctccagctgc ctcctaccat acactggagt gttgtttagt
     5161 aataatgtgt atttcaaatg cactacatgt ttttgaggga ttgtttatca tgtatttact
     5221 gaatttccat gtccgggctc tgtcattagg cactgtagct atatggacac tctctgtgtt
     5281 aaggacttaa cttggacttt tagtcagcac atggtgggaa tttctccttt ctccactggc
     5341 acagtggcca atacctcccc tttcctttcc tttcctttcc tttcctttcc tttcctttcc
     5401 tttcctttcc tttcctttcc tgttgttgtt tgtttgtttg tttgcttgag cttgtcacta
     5461 ggcagaggaa ttctgtttga aggaactagc tattaagtta ggtggccttt gcctagcccc
     5521 ttatcccttt tgaataaagc aacatgcatc ttttgttgtt aaatgcttct tttttgaagc
     5581 attttctcga ctctatgaat cccctattta gtctgcctta aagtgaaaca acgaccagtg
     5641 aaccgaagca tgacatttta ccagctgtgc agtggttagc taagtgtgtc ttgagatgtt
     5701 agcatcatca tgcacttaaa cttgacacta gggctatttt acaaacctta acaaacaaaa
     5761 cagatgccac cttgtacatt atcctgttac tgagctaaaa atccaaatag caatcatggg
     5821 catgctttag aactgtggtt tcaggcaggg gtatacatcc tgggggtatg cagatactaa
     5881 gtccattgag aaaatgttaa aataatgatt ctttgtattt aatctcatcc ttttaaattt
     5941 ctatttttat gtgttttata atgtacataa tatattgtac agttgtacac ttatataatt
     6001 tataaataaa taatacattt attggtgcat taaaaaaaaa aaaaaaaaaa aaaaaaaa
//
