LOCUS       NM_146013               2956 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus SEC14-like lipid binding 4 (Sec14l4), mRNA.
ACCESSION   NM_146013
VERSION     NM_146013.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2956)
  AUTHORS   Herbas,M.S., Okazaki,M., Terao,E., Xuan,X., Arai,H. and Suzuki,H.
  TITLE     alpha-Tocopherol transfer protein inhibition is effective in the
            prevention of cerebral malaria in mice
  JOURNAL   Am J Clin Nutr 91 (1), 200-207 (2010)
   PUBMED   19923370
  REMARK    GeneRIF: Deficiency of alpha-tocopherol in the circulation prevents
            cerebral malaria suggesting that this protein may be involved in
            early prevention of malaria.
REFERENCE   2  (bases 1 to 2956)
  AUTHORS   Shibata,N., Jishage,K., Arita,M., Watanabe,M., Kawase,Y.,
            Nishikawa,K., Natori,Y., Inoue,H., Shimano,H., Yamada,N.,
            Tsujimoto,M. and Arai,H.
  TITLE     Regulation of hepatic cholesterol synthesis by a novel protein
            (SPF) that accelerates cholesterol biosynthesis
  JOURNAL   FASEB J 20 (14), 2642-2644 (2006)
   PUBMED   17077281
  REMARK    GeneRIF: The expression of SPF in response to food deprivation and
            fibrate administration is reported in wild-type and knockouk mice.
REFERENCE   3  (bases 1 to 2956)
  AUTHORS   Yeh,C.H. and Shatkin,A.J.
  TITLE     A HeLa-cell-encoded p21 is homologous to transcription elongation
            factor SII
  JOURNAL   Gene 143 (2), 285-287 (1994)
   PUBMED   8206389
REFERENCE   4  (bases 1 to 2956)
  AUTHORS   Hirashima,S., Hirai,H., Nakanishi,Y. and Natori,S.
  TITLE     Molecular cloning and characterization of cDNA for eukaryotic
            transcription factor S-II
  JOURNAL   J Biol Chem 263 (8), 3858-3863 (1988)
   PUBMED   3346229
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC026948.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026948.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2956
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 2.84 cM"
     gene            1..2956
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /note="SEC14-like lipid binding 4"
                     /db_xref="GeneID:103655"
                     /db_xref="MGI:MGI:2144095"
     exon            1..118
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1276
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /note="SEC14-like 2; alpha-tocopherol associated protein;
                     supernatant protein factor; squalene transfer protein;
                     SEC14-like 4"
                     /codon_start=1
                     /product="SEC14-like protein 4"
                     /protein_id="NP_666125.1"
                     /db_xref="CCDS:CCDS24374.1"
                     /db_xref="GeneID:103655"
                     /db_xref="MGI:MGI:2144095"
                     /translation="MRGQVGDLSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRA
                     RNFDLKKSEDMLRKHVEFRNQQNLDQILTWQAPEVIQLYDSGGLSGYDYEGCPVWFDI
                     IGTMDPKGLFMSASKQDMIRKRIKVCEMLLHECELQSQKLGRKIERMVMVFDMEGLSL
                     RHLWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIV
                     ILGGNWKQELVKFVSPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKRYYLSNQERP
                     QYEHSVVVGRGSSHQVENEILFPGCVLRWQFASDGGDIGFGVFLKTRMGERQKAGEMV
                     EVLPSQRYNAHMVPEDGSLNCLKAGVYVLRFDNTYSLLHTKKVGYTAEVLLPDKACEE
                     KLQGLGSVSPP"
     exon            119..194
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            195..238
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            239..298
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            299..487
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            488..583
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            584..644
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            645..728
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            729..835
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            836..975
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1145
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..2956
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1388
                     /gene="Sec14l4"
                     /gene_synonym="SPF; TAP"
                     /note="major polyA site"
ORIGIN      
        1 gcagcagacc tgctaagtaa agccctgtga aggtggcagc agctgaggcc tagcagagag
       61 caccatgaga ggacaagtcg gggacctgag cccgcagcag caggaggctc tggccaggtt
      121 ccgggagacc ctccaggatc tgctgcccac cctgcccaag gccgatgact acttccttct
      181 gcgatggctc cgagctcgga actttgacct taagaaatct gaggacatgc tccgaaagca
      241 tgtggagttc cggaatcagc agaacctgga ccagatcctg acgtggcagg caccagaggt
      301 gatccaactc tatgactctg gtggtctgtc tggctatgac tacgaaggct gccctgtgtg
      361 gtttgacatc attgggacaa tggaccccaa aggccttttt atgtcagcct ctaagcagga
      421 catgatccgg aagcgtatca aagtctgtga gatgcttctc catgagtgtg agctgcagag
      481 tcaaaagttg ggcaggaaga ttgagagaat ggtgatggtg ttcgacatgg aagggctgag
      541 tctgaggcac ttatggaagc cagctgtgga ggtctaccag cagttttttg ccatcttgga
      601 agcaaattat cctgagacgg tgaaaaattt aatcattatt cgagccccca agctcttccc
      661 agtggccttc aacctggtca aatcattcat gggagaggag acacaaaaga agatagtgat
      721 tctgggaggt aactggaaac aagagcttgt caagtttgtg agccctgacc agctgcctgt
      781 ggaatttggg ggcaccatga ctgaccctga tggtaacccc aagtgcctga ccaagatcaa
      841 ctatgggggt gaggtgccga agcgctatta cctgagcaat caggagaggc cacagtatga
      901 gcacagtgtg gtcgtgggcc gaggctcctc ccaccaggtg gagaatgaga tcctgttccc
      961 aggctgtgtg ctcaggtggc agtttgcttc agatggtgga gacatcggct ttggagtttt
     1021 cctgaagacc aggatggggg agcggcagaa ggctggggag atggtggagg tgctgcccag
     1081 ccagcgctac aatgcccaca tggtgcccga ggatgggagc ctcaactgcc tcaaggctgg
     1141 agtctatgtc ctgcgctttg acaacaccta cagcctcctg cataccaaga aggtcggcta
     1201 cactgcggag gtgcttcttc cagacaaggc ctgtgaggag aagttgcagg gcctaggctc
     1261 agtgagccct ccttaggaca gtgaagactc tggccacctc tgattttact ccatccaact
     1321 ccttcacaca cccctactcc ttgcacccca ggcagggtga tgctgaacat ggctacagag
     1381 atctccaacc cttgtctcca tcttagcctc ccttcggacc actcagacac agaccagcac
     1441 tttcatcccc tatacccaga gaatggggct gagggtgaca tcacatgtcc actgagaaag
     1501 gacaccgccc catggtctca tccttctgaa gatacccaca cacccatgat tcagccatgc
     1561 ctggcatccc agctgggatt ggatacatga aatccacgtc tggttcccca taggaagcac
     1621 agctgcaggc tggcttctct ccaactggag gtcagcaagg atgggaaggg ccagctggag
     1681 gcagctgggc agactgtgaa ggggaagagg ccccagcttg aacagagcat caagaccttt
     1741 caaccccccc ccctttggaa gaaacagcag acgtggagag gcagggcatg gcgggggaac
     1801 ccagaagaaa agccacactc ggcttcatga ggtggagcag tttgctgaca tgtgatgtca
     1861 cccttagaca catacacata cgaacacaca tgtgcacgtg cgcctcctgc acatacacac
     1921 acctgctagg accttactga tactcaattt tgacattccc tctctcttaa ggcagtcgct
     1981 cactctgtag cccaggctgg ccttgcatta gtctgccttc tttggtgttg catatgggca
     2041 ccactatgcc tggcccgggt ggaactcagg accaaagcta aacagcagga ggcacaggta
     2101 ctagagggca gggtgagcca ctccggggat tcgtcctgac ctctcacttg cttcttggag
     2161 aaccttctag atttccatcc gtctgcatgt ctaaggagag agttgaagct gccaacatca
     2221 cttcccgtgt gacccaggag ctggcaggtg acagcttgtt gtgtgtgatg tctcaaaggc
     2281 tggccctcct ggcatacaca gacagcccgc tactgctcca ctaggtgtac tgaacctaac
     2341 agcagatgct gctgagtttg atccagtgtg cctctgtgga ttggctctga ggagcgatga
     2401 cctggggccc aggagcttag gctgtcctgc actgcttctc ctgggcctct ggctgggaca
     2461 gaagacccgt gtcccattca gggtggctta gacactgtct taggttactg acgttgcctt
     2521 ctttgtttgt ccttctgtgc tgctgggcca actgtccctg gaatgaatga tcagatagat
     2581 gtttctggaa agggagtcct tactctaaag tgccatcggc ctagaagcct tagcagaaac
     2641 caccttgtca aggcgccttg caggcgagac ttcaggcccc accgtcttct gcttccggat
     2701 cctatctttg gttttctctg cttgctgaac agatgtcttc attatcaaag gcattttaat
     2761 ggagaaaaac agtaaacctg gaagatgagg gagctcttca gaggagcccc tagtgagtgt
     2821 atctggacca gttggactat ttgcagtcaa ggcttagagt ctgcattggg ggttaaatgc
     2881 caagaggcag tgccaggaga aattcttgcc taagatcagc ttaagcagat tgtcaagagg
     2941 aaaaaaaaaa aaaaaa
//
