LOCUS       NM_024206               1301 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus SEC13 homolog, nuclear pore and COPII coat complex
            component (Sec13), mRNA.
ACCESSION   NM_024206
VERSION     NM_024206.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Wu,D., Zhang,H., Li,F., Liu,S., Wang,Y., Zhang,Z., Wang,J. and
            Wu,Q.
  TITLE     Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1
            ubiquitination in ALI
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1870 (8), 167475 (2024)
   PUBMED   39159700
  REMARK    GeneRIF: Sec13 promotes glycolysis by inhibiting Ubqln1 mediated
            Pgm1 ubiquitination in ALI.
REFERENCE   2  (bases 1 to 1301)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1301)
  AUTHORS   Liu,Z., Yan,M., Lei,W., Jiang,R., Dai,W., Chen,J., Wang,C., Li,L.,
            Wu,M., Nian,X., Li,D., Sun,D., Lv,X., Wang,C., Xie,C., Yao,L.,
            Wu,C., Hu,J., Xiao,N., Mo,W., Wang,Z. and Zhang,L.
  TITLE     Sec13 promotes oligodendrocyte differentiation and myelin repair
            through autocrine pleiotrophin signaling
  JOURNAL   J Clin Invest 132 (7) (2022)
   PUBMED   35143418
REFERENCE   4  (bases 1 to 1301)
  AUTHORS   Bruno,J., Brumfield,A., Chaudhary,N., Iaea,D. and McGraw,T.E.
  TITLE     SEC16A is a RAB10 effector required for insulin-stimulated GLUT4
            trafficking in adipocytes
  JOURNAL   J Cell Biol 214 (1), 61-76 (2016)
   PUBMED   27354378
REFERENCE   5  (bases 1 to 1301)
  AUTHORS   Moreira,T.G., Zhang,L., Shaulov,L., Harel,A., Kuss,S.K.,
            Williams,J., Shelton,J., Somatilaka,B., Seemann,J., Yang,J.,
            Sakthivel,R., Nussenzveig,D.R., Faria,A.M. and Fontoura,B.M.
  TITLE     Sec13 Regulates Expression of Specific Immune Factors Involved in
            Inflammation In Vivo
  JOURNAL   Sci Rep 5, 17655 (2015)
   PUBMED   26631972
  REMARK    GeneRIF: Sec13 regulates specific expression of immune factors with
            key functions in inflammation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1301)
  AUTHORS   Suntharalingam,M. and Wente,S.R.
  TITLE     Peering through the pore: nuclear pore complex structure, assembly,
            and function
  JOURNAL   Dev Cell 4 (6), 775-789 (2003)
   PUBMED   12791264
  REMARK    Review article
REFERENCE   7  (bases 1 to 1301)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 1301)
  AUTHORS   Ko,C., Lee,T.L., Lau,P.W., Li,J., Davis,B.T., Voyiaziakis,E.,
            Allison,D.B., Chua,S.C. Jr. and Huang,L.S.
  TITLE     Two novel quantitative trait loci on mouse chromosomes 6 and 4
            independently and synergistically regulate plasma apoB levels
  JOURNAL   J Lipid Res 42 (5), 844-855 (2001)
   PUBMED   11352992
  REMARK    Erratum:[J Lipid Res 2001 Oct;42(10):1714]
REFERENCE   9  (bases 1 to 1301)
  AUTHORS   Naylor,S.L., Carritt,B., Boileau,C., Beroud,C., Alexander,C.,
            Allderdice,P., Alimov,A., Ashworth,T., Bonifas,J., Bugert,P.,
            Buys,C.H., Chipperfield,M.A., Deng,G., Drabkin,H., Gemmill,R.M.,
            Grompe,M., Joensuu,T., Jonasdottir,A., Gizatullin,R., Krols,L.,
            Leach,R.J., Lott,S.T., Killary,A., Martinsson,T., Messiaen,L. et
            al.
  TITLE     Report of the sixth international workshop on human chromosome 3
            mapping 1995
  JOURNAL   Cytogenet Cell Genet 72 (4), 255-270 (1996)
   PUBMED   8641130
REFERENCE   10 (bases 1 to 1301)
  AUTHORS   Swaroop,A., Yang-Feng,T.L., Liu,W., Gieser,L., Barrow,L.L.,
            Chen,K.C., Agarwal,N., Meisler,M.H. and Smith,D.I.
  TITLE     Molecular characterization of a novel human gene, SEC13R, related
            to the yeast secretory pathway gene SEC13, and mapping to a
            conserved linkage group on human chromosome 3p24-p25 and mouse
            chromosome 6
  JOURNAL   Hum Mol Genet 3 (8), 1281-1286 (1994)
   PUBMED   7987303
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK003354.1.
            
            On Apr 6, 2007 this sequence version replaced NM_024206.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003354.1, BC002128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1301              AK003354.1         2-1302
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 52.84 cM"
     gene            1..1301
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /note="SEC13 homolog, nuclear pore and COPII coat complex
                     component"
                     /db_xref="GeneID:110379"
                     /db_xref="MGI:MGI:99832"
     exon            1..37
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1003
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /note="SEC13-like protein 1; SEC13-related protein; SEC13
                     related; SEC13-like 1; GATOR complex protein SEC13; GATOR2
                     complex protein SEC13"
                     /codon_start=1
                     /product="protein SEC13 homolog"
                     /protein_id="NP_077168.2"
                     /db_xref="CCDS:CCDS39596.1"
                     /db_xref="GeneID:110379"
                     /db_xref="MGI:MGI:99832"
                     /translation="MVSVMNTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRN
                     GGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHSGH
                     DSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAP
                     AVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWREEEDGQWKEEQKLEAHSDWVRDV
                     AWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNMWSPKLLHKFNDVVWHVSWSITANI
                     LAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASITEGQQNEQ"
     exon            38..82
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            83..198
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            199..350
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            351..484
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            485..618
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            619..742
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            743..889
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1301
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1264..1269
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /note="hexamer: AATAAA"
     polyA_site      1286
                     /gene="Sec13"
                     /gene_synonym="1110003H02Rik; Sec13l1; Sec13r"
                     /note="major polyA site"
ORIGIN      
        1 acgtccgagg ccgtgggtcg ccgctgctgc agctatggtg tcagtaatga acactgtgga
       61 cacctctcat gaggacatga ttcatgatgc acagatggac tactacggca cccgcctagc
      121 aacctgctcc tcggataggt ccgtcaaaat tttcgatgtg cggaatggag ggcagatcct
      181 catcgcagac ctcagaggac atgaggggcc agtatggcaa gtggcctggg cccaccccat
      241 gtatggcaat atcctggcct cctgttccta tgaccggaaa gtcatcatct ggaaggagga
      301 aaacggcact tgggagaaga cccatgagca ctcgggacac gactcctcag tgaactctgt
      361 ttgctgggcc cctcatgact atggcctgat cctggcctgt gggagttcag atggggccat
      421 ctcactgctg acctatacag gggaaggcca gtgggaagtg aagaagatta acaatgctca
      481 cacgattggc tgtaatgctg tcagttgggc cccagcagtt gtgcctggaa gccttataga
      541 ccaaccatca gggcagaaac ccaattacat caagaagttt gcatcaggtg gctgtgacaa
      601 cctcatcaag ctatggaggg aagaggagga tggccagtgg aaggaggagc agaagctaga
      661 ggcacacagc gactgggtcc gagatgttgc ctgggccccc tccattggct tgcccaccag
      721 caccattgcc agctgctctc aggatggtcg agtgtttatt tggacctgtg acgatgcctc
      781 aggcaatatg tggtcaccta aactcctaca caagttcaat gatgttgtgt ggcacgtgag
      841 ctggtccatc acagccaaca tcctggctgt gtcaggtgga gacaataagg tgaccctgtg
      901 gaaagagtcg gtggacggac agtgggtgtg catcagtgac gtcaacaagg gccagggttc
      961 tgtgtcagcc tccatcacag agggccaaca gaacgagcag tgacagcaca ggcagcctgg
     1021 ccttcctgtt acctattctg gaacaacctc caaacaactg ggaagaagag tcccagtgct
     1081 accaagattc cacacccgag tgcccacaca tgcaacactg ggtgttcacc tgccttactg
     1141 ggatcccatg tgtttagtaa tttaacgtcc agctgaaagt attcatgtaa ggaacaaatg
     1201 actattattt ttaaatattt ttggccattt ttaactatct tttggttaaa agctatccaa
     1261 gctaataaaa tcatattgca tagaaacttt actgtcatcc c
//
