LOCUS       NM_025468                770 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus SEC11 homolog C, signal peptidase complex subunit
            (Sec11c), mRNA.
ACCESSION   NM_025468
VERSION     NM_025468.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK007641.1.
            
            On Apr 5, 2007 this sequence version replaced NM_025468.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007641.1, CK032550.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-770               AK007641.1         2-771
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 38.98 cM"
     gene            1..770
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /note="SEC11 homolog C, signal peptidase complex subunit"
                     /db_xref="GeneID:66286"
                     /db_xref="MGI:MGI:1913536"
     exon            1..134
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..626
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /EC_number="3.4.21.89"
                     /note="SPC21; SEC11-like protein 3; SPase 21 kDa subunit;
                     microsomal signal peptidase 21 kDa subunit; Sec11-like 3"
                     /codon_start=1
                     /product="signal peptidase complex catalytic subunit
                     SEC11C"
                     /protein_id="NP_079744.1"
                     /db_xref="CCDS:CCDS29309.1"
                     /db_xref="GeneID:66286"
                     /db_xref="MGI:MGI:1913536"
                     /translation="MVRAGAVGTHLPTSSLDIFGDLRKMNKRQLYYQVLNFAMIVSSA
                     LMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGR
                     DIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPY
                     VGMVTIIMNDYPKFKYALLAVMGAYVLLKRES"
     exon            135..244
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /inference="alignment:Splign:2.1.0"
     exon            245..394
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /inference="alignment:Splign:2.1.0"
     exon            395..514
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /inference="alignment:Splign:2.1.0"
     exon            515..572
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /inference="alignment:Splign:2.1.0"
     exon            573..770
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      770
                     /gene="Sec11c"
                     /gene_synonym="1810029G24Rik; Sec11l3"
                     /note="putative"
ORIGIN      
        1 gtgacagaca gagccggccg gccgcctggg cccccagaga ccccgccatg gttcgtgcgg
       61 gcgccgtggg gacgcatctc cccacgtcca gcctggacat ctttggggac ctgaggaaga
      121 tgaacaaacg acagctctac taccaggttt taaactttgc catgatcgtg tcttctgcgc
      181 tcatgatctg gaaaggcctg attgttctca cgggcagcga gagtcccatc gtggtggtac
      241 tcagtggcag tatggagccg gccttccaca gaggagatct gctgttcctc acgaatttcc
      301 gggaggaccc catcagagct ggtgaaatag ttgtttttaa ggttgaagga agagacattc
      361 cgatagttca cagagtaatc aaggttcatg aaaaagataa tggtgacatc aagtttctga
      421 ctaaaggaga taataatgaa gtcgatgata gaggcttgta caaagaaggc cagaactggc
      481 tggagaagaa ggacgtggta ggaagagctc gagggttctt accttatgtt ggcatggtca
      541 ccatcataat gaatgactat ccaaaattca agtatgctct tttggctgtg atgggtgcat
      601 atgtgttact aaaacgtgaa tcctaacatg agaagcagtt cctgggacca gaccgaaatg
      661 agttctgttg aaaaagagaa aagctaatat atttgaaatg ttccactttc tgtataaaga
      721 gaaaccaggt ggggatgttt ttgtcttatc taaataaatg attcaccagt
//
