LOCUS       NM_001418556            1145 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus SEC11 homolog A, signal peptidase complex subunit
            (Sec11a), transcript variant 3, mRNA.
ACCESSION   NM_001418556
VERSION     NM_001418556.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123744.8.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189676.163265.1, CA978232.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AC123744.8         87830-87975         c
            147-256             AC123744.8         75455-75564         c
            257-406             AC123744.8         68165-68314         c
            407-439             AC123744.8         66026-66058         c
            440-559             AC123744.8         63529-63648         c
            560-617             AC123744.8         56603-56660         c
            618-1145            AC123744.8         55805-56332         c
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 45.71 cM"
     gene            1..1145
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /note="SEC11 homolog A, signal peptidase complex subunit"
                     /db_xref="GeneID:56529"
                     /db_xref="MGI:MGI:1929464"
     exon            1..146
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..668
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /EC_number="3.4.21.89"
                     /note="isoform 3 is encoded by transcript variant 3;
                     signal peptidase complex catalytic subunit SEC11A; sid
                     2895; endopeptidase SP18; SEC11-like protein 1; SPase 18
                     kDa subunit; microsomal signal peptidase 18 kDa subunit;
                     signal peptidase complex (18kD); Sec11-like 1"
                     /codon_start=1
                     /product="signal peptidase complex catalytic subunit
                     SEC11A isoform 3"
                     /protein_id="NP_001405485.1"
                     /db_xref="GeneID:56529"
                     /db_xref="MGI:MGI:1929464"
                     /translation="MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITG
                     SESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIH
                     ENSAGERKHSICWQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYI
                     GIVTILMNDYPKFKYAVLFLLGLFVLVHRE"
     exon            147..256
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     exon            257..406
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     exon            407..439
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     exon            440..559
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     exon            560..617
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     exon            618..1145
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      941..946
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /note="hexamer: ATTAAA"
     polyA_site      959
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /note="major polyA site"
     regulatory      1123..1128
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /note="hexamer: AATAAA"
     polyA_site      1145
                     /gene="Sec11a"
                     /gene_synonym="1810012E07Rik; 18kDa; Sec11l1; sid2895;
                     Sid2895p; Spc18"
                     /note="major polyA site"
ORIGIN      
        1 ctgtccacgg tgagcccggc ccgtgttgca gcggtccctc ttggtggttc tatcgcgccc
       61 tcttggctgc tagttgtcgc gctctccatc tcaccatgct gtctctagac tttctagacg
      121 atgtgcggcg gatgaacaag aggcagctgt actaccaagt cctaaatttt ggaatgattg
      181 tctcctcggc actaatgatc tggaaggggc tgatggtgat aaccggaagt gagagtccaa
      241 ttgtagtggt gctcagtggc agcatggagc ctgcgtttca cagaggggat ctccttttcc
      301 tcacgaaccg agttgaagat cctatacgcg tgggggagat cgttgttttc aggatagaag
      361 gaagagagat tcctatagtg caccgagtcc tgaagatcca tgaaaactca gcaggggaaa
      421 gaaagcacag tatttgctgg caagatgggc atatcaagtt tttaaccaaa ggagataata
      481 atgctgttga tgaccgaggt ctctataaac aaggacaaca ctggctggag aagaaagatg
      541 ttgtggggag agcaagaggg tttgttcctt acattggaat tgtgacgatc ctcatgaatg
      601 actatcctaa atttaagtat gcagtactgt ttctgctcgg tttatttgtg ctggtccatc
      661 gtgagtaaga agtcggactc cctgttccta ggaagctgct gtgcttgttg ttactgaatg
      721 ttggagtaga tcctgatctg tgattgcgga ttttcggagg acacacacgt tggcacttct
      781 tggtagccct ggtttgcatt gctttgtgtt tccacacccg aggctgtgtg ggcgggtgca
      841 tgtgcaccgt ggagtgcaca caaggggact gtcaatcaca gggtttcata tgttgtcatt
      901 gtcactcttt cacatttttg tacatcagtg aattttttat attaaaaggt tgagccaaag
      961 cccccagtgt ttgtattttg aagccaagct tcactttaaa agtgcctaca gagttctgta
     1021 aatgaaaaca cagctctgca tgagttcaaa cctgtcgttc ctccttacag taggaatggc
     1081 acatattgag gcgatcataa gtcttaactt ttcaaaattt taaataaaag actttgcaca
     1141 ttgaa
//
