LOCUS       NM_001357273            2618 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus short chain dehydrogenase/reductase family 42E, member
            1 (Sdr42e1), transcript variant 2, mRNA.
ACCESSION   NM_001357273 XM_006531407
VERSION     NM_001357273.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112964.8.
            
            On Oct 25, 2017 this sequence version replaced XM_006531407.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC038819.1, SRR3224864.5265.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                AC112964.8         33427-33516
            91-184              AC112964.8         42036-42129
            185-2618            AC112964.8         43284-45717
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 64.69 cM"
     gene            1..2618
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /note="short chain dehydrogenase/reductase family 42E,
                     member 1"
                     /db_xref="GeneID:74032"
                     /db_xref="MGI:MGI:1921282"
     exon            1..90
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            91..184
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1301
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /product="short-chain dehydrogenase/reductase family 42E
                     member 1"
                     /protein_id="NP_001344202.1"
                     /db_xref="CCDS:CCDS22701.1"
                     /db_xref="GeneID:74032"
                     /db_xref="MGI:MGI:1921282"
                     /translation="MDSPRFPEETVLITGGGGYFGFRLGCALNQKGARVILFDITQPA
                     QNLPEGIKFVCGDIRCLADVETAFQDAEKVACVFHVASYGMSGREQLNKTQIEEVNVG
                     GTENILRACLERGVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIA
                     EKKVLEANGLAFKQGDGILRTCAIRPAGIYGAGEQRHLPRIVSYIERGLFRFVYGDPQ
                     SLVEFVHVDNLAKAHILASEALKADKGHVASGQPYFISDGRPVNNFEFFRPLVEGLGY
                     TFPSTRLPLTLIYCLAFLVEMTHFIVGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKE
                     LGFEPQPFDLQEVVEWFKAHGHGRGAAGQDSEFMLWDGILILLLALSVLTWILPSTTL
                     SI"
     exon            185..2618
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2598..2603
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2615
                     /gene="Sdr42e1"
                     /gene_synonym="4632417N05Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtttgacag cttttgctct agagcggggg cagcaaggca ccagaggctc tttcgtcttg
       61 cttctacaag ccacgctgtc gtctgcctct gtccagttgt cccttcgctg tctcacatgg
      121 actccccaag gttcccagag gaaaccgtcc tcatcactgg aggaggagga tattttggct
      181 ttcgcctcgg ctgcgccctg aaccagaaag gagcccgtgt gattctgttt gacatcaccc
      241 aaccagccca gaaccttcca gagggaatca aattcgtctg cggagatatc cgctgcctcg
      301 ctgacgtgga gacggctttc caggatgctg agaaagttgc gtgcgtgttc cacgtcgcct
      361 cttacggcat gtctgggagg gagcaactga acaagaccca gatcgaagag gtcaacgtgg
      421 gtggcacaga gaacatcctc cgggcctgcc tggagagagg agtgcccaga ttagtctaca
      481 caagcacatt caatgtcatc tttggaggtc aagtcatcag aaatggggac gagtctctgc
      541 cttacctgcc tcttcaccta cacccggatc actactccag gaccaagtcc atcgcagaga
      601 agaaggtcct ggaagccaat ggcttggcct tcaagcaggg cgatggtata ctccggacct
      661 gcgccatcag gccagccggc atctacgggg ctggggagca gaggcatctt cccaggatag
      721 tgagttacat tgagaggggc ctgttcagat ttgtgtacgg ggatccccag agcctggttg
      781 agtttgtcca cgtggataac ctggcgaagg ctcacattct ggcctctgag gctctgaaag
      841 ccgataaagg ccacgttgcc tccggtcagc cctacttcat ctcagatggt agaccggtca
      901 ataactttga gttctttagg ccactggtcg agggcctggg ctacacattc ccatccaccc
      961 gcctgcccct aaccctcatc tactgccttg ctttcttggt agagatgacc cacttcattg
     1021 tgggcaggct ctacaacttc cagcccttcc tcacccgcac cgaagtttat aaaactggcg
     1081 tcacacatta cttcagctta gagaaagcca agaaagagct aggcttcgag cctcagccat
     1141 ttgacctgca ggaggtagta gagtggttta aagcccatgg tcacggccga ggggctgcgg
     1201 gtcaagactc ggagtttatg ctgtgggatg gaattctgat cctactcctg gcactttctg
     1261 ttcttacctg gatccttccc tccaccaccc tgtccatatg aagaggaaag ctatccacag
     1321 gagctgagcc tccttcctgg gatgggttca aagatgcagg ttttgaaaga tgtgtctcat
     1381 tatctggtac cattcctgga tcctcacatt acttcttaaa agtgagtctt taaacttcat
     1441 ggccagggat gggttacctc ctgatgagtg gttgatgggg gagactcctg agacctccaa
     1501 agcagtattg gctgtggcca atgctcttgg ttgcccacca gcaactagct agtaagactc
     1561 tattgcctaa ggtgccatac accttaactg aagcacataa agagatccag ctggaaccga
     1621 actgggggct tcctgcctgc ttgctagatt tcatagttcc agaagggtct atgcaggcta
     1681 ctggagtctt attcagccgt ggaccctgca tacagcacta tcaatactgg gaaaaggtgt
     1741 accctctagt gcaacagcga tatgtctgtt aggggaataa ccaactactt cagaattgaa
     1801 ctggaggctg gctccatggg agggagagtt tgttcctggt actataaacc tgtccagagg
     1861 ctcatggata gagaggtcat aggccaagta tggcctaccg ctgttagttt tgtcggatag
     1921 agaagctgtg cccgtgacgc tacttcctaa gttcttacat ttatatctgt agattagtgc
     1981 tactctcagc tgtgatcaga ggtgcttctc tctgccgtag gggcaccagt tatacttctg
     2041 agattcatat ccggtccaag tgctgagtgt tgagtgttca tccatagaca agacacccta
     2101 ttagcctccc tcatagcctc acaggactct gtagcaaaag gggtaggaag gacgcaaaag
     2161 ctggaggaag gtagggggcg ggtgttgggg agtctgtctg ctgagaatga aatgactact
     2221 gtccccgtga cctaacggta actgtgatgc actactagac tcatacgctg aggcctatca
     2281 ccatcctgcc atgggaaggg gagaagctcg atacctactc ctccctgaaa agctgaggtg
     2341 actggtggtt tctggggagc gggagacact ttctctagtg gtttcgtaac ttctgaattg
     2401 ccccatgccc ctgtaagcaa gcttagtgaa actctctggg acacacacac acatacacac
     2461 agtttagaca ggaatctagt tgggaagaga ctgggaatgg gacaaaagag ggtgtggggg
     2521 tgaatcggat cgaactacgt tatatacatg ttcgaaatgt tataatgaaa ctgttatata
     2581 cttaacccat gctaataaat aaaaaggaaa aatgactt
//
