LOCUS       NM_001417719            1082 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus succinate dehydrogenase complex assembly factor 3
            (Sdhaf3), transcript variant 1, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001417719 XM_030255595
VERSION     NM_001417719.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1082)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1082)
  AUTHORS   Dennis,R.A. and McCammon,M.T.
  TITLE     Acn9 is a novel protein of gluconeogenesis that is located in the
            mitochondrial intermembrane space
  JOURNAL   Eur J Biochem 261 (1), 236-243 (1999)
   PUBMED   10103055
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122240.4 and AC146599.3.
            
            On Mar 9, 2023 this sequence version replaced XM_030255595.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.5169072.1,
                                           SRR13422590.148961.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               AC122240.4         199239-199435
            198-274             AC122240.4         200239-200315
            275-1082            AC146599.3         132361-133168
FEATURES             Location/Qualifiers
     source          1..1082
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 2.83 cM"
     gene            1..1082
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /note="succinate dehydrogenase complex assembly factor 3"
                     /db_xref="GeneID:71238"
                     /db_xref="MGI:MGI:1913288"
     exon            1..197
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..413
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; protein ACN9 homolog, mitochondrial; SDH
                     assembly factor 3; succinate dehydrogenase assembly factor
                     3, mitochondrial"
                     /codon_start=1
                     /product="succinate dehydrogenase assembly factor 3,
                     mitochondrial isoform a precursor"
                     /protein_id="NP_001404648.1"
                     /db_xref="GeneID:71238"
                     /db_xref="MGI:MGI:1913288"
                     /translation="MPGKHVSRVRALYRRILLLHRALPPDLKALGDQYVKDEFRRHKT
                     VGPGEAQRFLKEWENEGGERVLHDAEESCRISSHLENIRRRTQQCCGNKLRTADKAQL
                     EKRVLAPLSQKKNSMTFVMSKLDSCKS"
     exon            198..274
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /inference="alignment:Splign:2.1.0"
     exon            275..1082
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      543..548
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /note="hexamer: AATATA"
     polyA_site      562
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
     regulatory      818..823
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /note="hexamer: AATAAA"
     polyA_site      841
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /note="major polyA site"
     regulatory      1060..1065
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
                     /note="hexamer: AATAAA"
     polyA_site      1082
                     /gene="Sdhaf3"
                     /gene_synonym="0610005M07Rik; 4933430A16Rik; Acn9"
ORIGIN      
        1 accttctgcg caggcgcggc gcgatgccgg ggaagcatgt ctcgagagtc cgggctttat
       61 ataggcgaat cttgctgcta catcgggctc tgcccccgga cctcaaagcc ctgggtgacc
      121 agtacgtgaa ggacgaattt aggagacata agactgttgg tcctggcgag gcccagcgat
      181 tcttgaagga atgggagaat gaagggggag aaagagtatt gcatgatgct gaagagtctt
      241 gcaggatctc ctcccatctt gaaaatatca ggagacgtac gcagcagtgc tgtggcaaca
      301 agctgaggac agcagacaaa gctcaactgg aaaagcgtgt tttggcacct ctctcccaga
      361 agaaaaactc aatgactttc gtgatgagca aattggacag ttgcaagagc tgatgcaaga
      421 ggctactaaa cccaataggc agtttagtat cactgagtct acaaaaccac agttgtgata
      481 catgatctta acaaagtggc tacatttata acctgttacc tcatctacca ttgactctct
      541 aaaatatatt ctttcagcta cagaatagtc tcttattttt ggacagtatg aacaatgcat
      601 gatcaaaatc ataaatgacg cacttgtcat cattgcaatg acatatttat ttgctgtgtg
      661 gaatgtagtt ttatggaatt taatttctgg actaaagaaa ggtgttaaaa aagatatact
      721 ttgggattat gctgaaattt ttttgtatat gaatttgttt taaattctat ccccatcaag
      781 tgttagcctc ctgatttgtc tctagcttca tcagttaaat aaacatatca taataatgga
      841 agatgtagaa ttccaataag tttgctatta gacatattgt gattctgaaa gtcccaccat
      901 ttctccttta gtagtacaca cctggctatc actcagaatt tcatctatga gtcacgttga
      961 aagttttaag aaaagcctta agattcaatt gttaagaatt tcagttattg tctaaaggtt
     1021 ggggagatga aaaatactaa gttggctcat acatttaaaa ataaattatc tatcaaaacc
     1081 tg
//
