LOCUS       NM_025333               3116 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus succinate dehydrogenase complex assembly factor 2
            (Sdhaf2), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_025333 XM_484826
VERSION     NM_025333.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3116)
  AUTHORS   Zhou,Z., Ma,A., Moore,T.M., Wolf,D.M., Yang,N., Tran,P., Segawa,M.,
            Strumwasser,A.R., Ren,W., Fu,K., Wanagat,J., van der Bliek,A.M.,
            Crosbie-Watson,R., Liesa,M., Stiles,L., Acin-Perez,R., Mahata,S.,
            Shirihai,O., Goodarzi,M.O., Handzlik,M., Metallo,C.M., Walker,D.W.
            and Hevener,A.L.
  TITLE     Drp1 controls complex II assembly and skeletal muscle metabolism by
            Sdhaf2 action on mitochondria
  JOURNAL   Sci Adv 10 (14), eadl0389 (2024)
   PUBMED   38569044
  REMARK    GeneRIF: Drp1 controls complex II assembly and skeletal muscle
            metabolism by Sdhaf2 action on mitochondria.
REFERENCE   2  (bases 1 to 3116)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3116)
  AUTHORS   Cheong,A., Archambault,D., Degani,R., Iverson,E., Tremblay,K.D. and
            Mager,J.
  TITLE     Nuclear-encoded mitochondrial ribosomal proteins are required to
            initiate gastrulation
  JOURNAL   Development 147 (10) (2020)
   PUBMED   32376682
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3116)
  AUTHORS   Liu,J., Gao,L., Zhang,H., Wang,D., Wang,M., Zhu,J., Pang,C. and
            Wang,C.
  TITLE     Succinate dehydrogenase 5 (SDH5) regulates glycogen synthase kinase
            3beta-beta-catenin-mediated lung cancer metastasis
  JOURNAL   J Biol Chem 288 (41), 29965-29973 (2013)
   PUBMED   23983127
REFERENCE   5  (bases 1 to 3116)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   6  (bases 1 to 3116)
  AUTHORS   Phillips,R.L., Ernst,R.E., Brunk,B., Ivanova,N., Mahan,M.A.,
            Deanehan,J.K., Moore,K.A., Overton,G.C. and Lemischka,I.R.
  TITLE     The genetic program of hematopoietic stem cells
  JOURNAL   Science 288 (5471), 1635-1640 (2000)
   PUBMED   10834841
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125093.4, AK167228.1, AC124169.3, AK160957.1 and BP771596.1.
            
            On Aug 6, 2009 this sequence version replaced NM_025333.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160957.1, BC085277.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AC125093.4         86611-86674
            65-861              AK167228.1         1-797
            862-862             AC124169.3         1715-1715
            863-1257            AK167228.1         799-1193
            1258-1708           AK160957.1         1165-1615
            1709-2220           AC124169.3         2562-3073
            2221-3075           AK160957.1         2128-2982
            3076-3116           BP771596.1         27-67               c
FEATURES             Location/Qualifiers
     source          1..3116
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 6.6 cM"
     gene            1..3116
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /note="succinate dehydrogenase complex assembly factor 2"
                     /db_xref="GeneID:66072"
                     /db_xref="MGI:MGI:1913322"
     exon            1..151
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            152..369
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            370..479
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            480..3097
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1239..1244
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /note="hexamer: ATTATA"
     polyA_site      1260
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /note="major polyA site"
     polyA_site      1927
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
     regulatory      1947..1952
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1968
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /note="major polyA site"
     regulatory      3055..3060
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3097
                     /gene="Sdhaf2"
                     /gene_synonym="0610038F07Rik"
ORIGIN      
        1 atacgctcgg ttgcgccttc cggcttgggg tccacctccg ctgaagtcct cagatcgacc
       61 gcccggaatt cccggaagtg gcccggttgc cagcttactg tgctataaga gagagatggc
      121 ggtggtcacc ttgatcccga cgctggcgcg ggcactgtca aagcacagtc tgctgtctcc
      181 cttgcctagt gtgacatcat tcagacgctt ctacagaggt gacagcccaa cagactctca
      241 aaaagacatg attgaaatcc ctttgcctcc gtggcaggag agaactgatg aatccataga
      301 aaccaaaaga gcccgcttac tctatgagag cagaaagagg gggatgctgg agaactgcat
      361 tctccttagc ctgtttgcta aagagtatct gcacaacatg acagagaagc agctgaacct
      421 ctatgatcgc ctgattaacg agcctagcaa tgactgggat atttactact gggccacaga
      481 agcaaaacca gccccagaaa tatttgaaaa tgaagtcatg gaattgctga gagaattcgc
      541 caaaaacaaa aacaaggagc agagactgcg tgccccagat ctggagtatc tctttgaaaa
      601 gcctcattaa gctgggtacc actgcctgtc atggtggtca gtatatggat agaaactgct
      661 tctggcactg accttggcct cctgcttctc cttagactct tgaatctctc ccaggaaaga
      721 catgtaatat gttagctgac tcattctaac ctgtgctcgt ctgtacagca caggtcagac
      781 cccttacctg gctgctaagt gctgtgctgc aggtctgcca caagagggca ctatagggga
      841 agtgattctg ctgcctcagc cccaacagta caaaagacac tgctgctgaa ggaagagctg
      901 accctatcgt ctatccagtg accctgggct ttgttaagat aaaactgctc ccttccagcg
      961 tgataagtcc tttgctaagg aatgtcggtc caagcccctg aactgagcca tcaaaggcac
     1021 agcaagctga atgaggcacc aaagcaggaa tattgtgggc ttactaagtc aacatcttca
     1081 tcaaattttc acaacataca tgttttaaac tgaaagatag ttgaatattg aagaatatta
     1141 agagaagaaa attgacagtt ctctaaccct cacaattatc ttcatttttg tctgtttcta
     1201 tgcaacctat agtcatgctt ataatggtgt tttacaaaat tatagtcata agttttctga
     1261 ctttgtggca ttgaggcaaa ctttctcctc attctgacag cctttcaaat tattttagtt
     1321 gaccaaataa cagtgacaca taagaagtaa cattttaact gcgtgtgata ggtcacacct
     1381 atgatcctag cccttggaga actgaggtag gaacatcact aagaatttga ggccagcctg
     1441 gaccacacgg ttagaatgca gtagctagga gagctgtgca gtcctgaagg catcctttct
     1501 gcaggagctc tgccctcagc tgcaaagagg cagtcactct ggccggtatg tgagtgttgg
     1561 ctagagaaag caggccagaa ctgagaagcc tgggtgggta actacaagag ctataggaaa
     1621 aagttccctg gccagggagg gaagcgggaa tcagcatcag ttacctcaca acgctcccac
     1681 agacaaatag cattgggcct acttaaggac aagagattgc cttggaagga gtcagcaatg
     1741 catccatgat caaaaagcca ggatttgggg ctggagagat ggctcagcgg ttaagagcac
     1801 tggctggctg ttcttctaga ggacctgatt cagtccctag cacccacaaa gcagctcaca
     1861 actgtctgta actctagttt caagaggatc tgacacagat gcaggtgaaa caccaacgaa
     1921 tattttttaa aaatcataaa aaggttaata aaaagacgaa agctggaata tattattgtt
     1981 tgatctacat ccaaagctca tgaacgttct gctagacaac acggtagcaa ccgtcactgg
     2041 acaattgaag gcaagaatga cagttctgag acagctctgt attgctctgt ggtaggtagg
     2101 aggccactag ctacttccca aagtgaggat ccacccagaa tcccccaggc cccactgtag
     2161 ctctggtaag aagatgcagg gtagcatggt gtacagtgta gcatggtggt tatgagtcca
     2221 agcctttgct ctattgctta gctgcaggat aaacttactg gcctaagctt tggtttctaa
     2281 ctaagggcga taatcactta agtctcaaga ttgctaaaag ctatgatagg taacactgga
     2341 tggcatctag cacccagaat agcatgggaa gacaggagcc tttgttcaaa gcctcaccct
     2401 gagacttaga gcctgtcttc taacagattg cctatcatca actgcacata tacacacagg
     2461 gcagtcatct gaaagtcaga aggctgagct tattaaaata accacagagt gcttttccag
     2521 aacgcaaagt ggaaggaaaa acctaccctg gtaacaagtc ctttgatgga aaagtttagc
     2581 tctcacttaa gcaaggaata ggaatgagac ctgtggagta gaagcaggag cttacagaga
     2641 tgctagctag ccctttgggc ttgtgatgtc ctagggggat ggaggtgcta aacagacagg
     2701 gtttatatat agaagcatct ggactgtaag gagcgcacag gaattgcgta gcaccttccc
     2761 catttatcac gggcatgtta cacaagaagc cccagaagcc aagtacgcac ctcagttctg
     2821 gtcccttctg gcccccgttc cgtcttcaca gtgttcagcc tgcacctggg aatggcttgc
     2881 ttctagagga gtggttttcc ttccaggcgg ctggcttgtg tcatctttga aagtgaagga
     2941 ctttgctaac taaagctgct cagcgtcaag cccaagggtg ctatgtaaac agttttttct
     3001 tttattagac attaagtaaa actaggccag ccacagtgca tttccaaaaa aattaataaa
     3061 catattgcca aggccagcag ctccccagga cccacgaaaa aaaaaaaaaa aaaaaa
//
