LOCUS       NM_011341               5255 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus stromal cell derived factor 4 (Sdf4), transcript
            variant 1, mRNA.
ACCESSION   NM_011341
VERSION     NM_011341.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5255)
  AUTHORS   Zhu,Y., Wang,Q., Xu,W. and Li,S.
  TITLE     The ethanol response gene Cab45 can modulate the impairment
            elicited by ethanol and ultraviolet in PC12 cells
  JOURNAL   J Genet Genomics 35 (3), 153-161 (2008)
   PUBMED   18355758
REFERENCE   2  (bases 1 to 5255)
  AUTHORS   Shirozu,M., Tada,H., Tashiro,K., Nakamura,T., Lopez,N.D.,
            Nazarea,M., Hamada,T., Sato,T., Nakano,T. and Honjo,T.
  TITLE     Characterization of novel secreted and membrane proteins isolated
            by the signal sequence trap method
  JOURNAL   Genomics 37 (3), 273-280 (1996)
   PUBMED   8938438
REFERENCE   3  (bases 1 to 5255)
  AUTHORS   Scherer,P.E., Lederkremer,G.Z., Williams,S., Fogliano,M.,
            Baldini,G. and Lodish,H.F.
  TITLE     Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen
  JOURNAL   J Cell Biol 133 (2), 257-268 (1996)
   PUBMED   8609160
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DN176224.1, BC068152.1 and
            CJ253941.1.
            
            On Oct 23, 2014 this sequence version replaced NM_011341.4.
            
            Summary: This gene encodes a member of the CREC family. The encoded
            protein contains multiple calcium-binding EF-hand motifs. This
            protein localizes to the Golgi lumen and may be involved in
            regulating calcium dependent cellular activities. Alternative
            splicing results in multiple transcript variants. [provided by
            RefSeq, Oct 2014].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1). Variants 1, 2 and 3
            encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068152.1, SRR1660813.249667.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                DN176224.1         1-71
            72-5019             BC068152.1         1-4948
            5020-5043           CJ253941.1         258-281
            5044-5255           BC068152.1         4971-5182
FEATURES             Location/Qualifiers
     source          1..5255
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 87.66 cM"
     gene            1..5255
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /note="stromal cell derived factor 4"
                     /db_xref="GeneID:20318"
                     /db_xref="MGI:MGI:108079"
     exon            1..492
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     exon            493..822
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     CDS             500..1585
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; 45 kDa calcium-binding protein"
                     /codon_start=1
                     /product="45 kDa calcium-binding protein isoform 1
                     precursor"
                     /protein_id="NP_035471.1"
                     /db_xref="CCDS:CCDS19054.1"
                     /db_xref="GeneID:20318"
                     /db_xref="MGI:MGI:108079"
                     /translation="MVWLVAMTPRQSSLCGLAAHGLWFLGLVLLMDATARPANHSSTR
                     ERAANREENEIMPPDHLNGVKLEMDGHLNKDFHQEVFLGKDMDGFDEDSEPRRSRRKL
                     MVIFSKVDVNTDRRISAKEMQHWIMEKTAEHFQEAVKENKLHFRAVDPDGDGHVSWDE
                     YKVKFLASKGHNEREIAEAIKNHEELKVDEETQEVLGNLRDRWYQADNPPADLLLTED
                     EFLSFLHPEHSRGMLKFMVKEIFRDLDQDGDKQLSLPEFISLPVGTVENQQGQDIDDN
                     WVKDRKKEFEELIDSNHDGIVTMEELENYMDPMNEYNALNEAKQMIAIADENQNHHLE
                     PEEILKYSEFFTGSKLMDYARNVHEEF"
     exon            823..959
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1073
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1232
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1408
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..5245
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1822..1827
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /note="hexamer: ATTAAA"
     polyA_site      1845
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /note="major polyA site"
     polyA_site      5222
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
     regulatory      5228..5233
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
                     /note="hexamer: AATAAA"
     polyA_site      5245
                     /gene="Sdf4"
                     /gene_synonym="Cab45"
ORIGIN      
        1 cgcgactcgg agactggaag gctcggaggc tggaaggcgc ctgcgcgact cggacgctgg
       61 aaggcgcctg cgcgactcgg acgctggaag gcgcctgcgc gactcgactc ggacgctgga
      121 aggcgcctgc gcgactcgga gactggcgcg gccggttagg cctggtaacg tgggaggagc
      181 cccgaggcgc accgtggctg ggggtttcga ctccccggag ctgatatcca gggcggcttt
      241 gaaggatagg gctgggccca gaatgattga cacgtgaccc cgcgcgccat tcctattggt
      301 tgcttcgcag aggctgcttc cgcccataag aaagatggcg gcttcgagat tcgtaccgga
      361 ggccgggtgt ttttttcccc accgttcccg gttgtcttat tcgccccttc ccggaagaaa
      421 gatggcggcg gcctgagccg agttctgcgt aagacttggc gggcgcccag acccggcgca
      481 tcagaagccg gggagtccca tggtctggct ggtggcaatg acgcccaggc agagttccct
      541 ctgtggtcta gctgctcatg gcctctggtt cttgggcctt gtccttctga tggatgcaac
      601 cgctagacct gccaaccact catctactcg ggaaagagcg gctaacaggg aggaaaatga
      661 gatcatgccc ccagaccacc tgaatggggt gaagctggag atggatggac acctcaacaa
      721 ggacttccat caggaggttt tcctgggaaa ggacatggat gggtttgatg aagactcaga
      781 gccacggaga agccggagga agctgatggt catcttttcc aaggtagacg tgaacactga
      841 ccggaggatc agcgctaagg agatgcagca ctggattatg gagaaaacag cagagcactt
      901 ccaggaggcc gtcaaggaaa acaaactgca cttcagggct gtggaccctg acggtgacgg
      961 ccatgtttcc tgggatgaat ataaagtgaa gtttttggca agcaaaggcc acaatgaaag
     1021 ggagattgct gaagccatca agaaccatga ggagctcaaa gtggatgagg agacacagga
     1081 agtccttggg aacctcagag accgatggta tcaggcagac aatcctcctg cagacctgct
     1141 gctgactgag gacgagttcc tttcattcct tcaccctgag cacagccggg gcatgctcaa
     1201 gttcatggtc aaggagatct ttcgggactt ggatcaggat ggtgataagc agttatctct
     1261 gcccgagttc atctctctgc ctgtgggtac tgttgagaac caacaaggcc aagacattga
     1321 tgacaactgg gtgaaagaca gaaagaagga gtttgaggaa ctgattgact ctaaccatga
     1381 tgggattgtg accatggagg agctagagaa ctacatggac cccatgaatg aatacaatgc
     1441 cctcaacgaa gccaaacaga tgattgccat tgctgatgag aaccagaacc accacctgga
     1501 gcccgaggag atcctcaagt acagtgagtt cttcaccggc agcaagctca tggactatgc
     1561 ccgcaacgtg catgaagagt tctgagcatg cccctcagct ggggccaggt cgccagtgtc
     1621 ctgtctgacc cttcccatgc ttcgaggagg ctatggtcca gtgagacctg tggatggctg
     1681 ggtccagatt gggtctaaaa tgctatctac cctgagtccg gaggcttcca taggccccaa
     1741 gaaagtgctg ttccagaacc tcctccttct gttgtgtcca tatgctctgg cttagctcct
     1801 gccatggcat ggcccaggtt tattaaagat atgcttaata ggctatgtgt cctctccagc
     1861 atgtgtctga ggcagtagcc cttctgtacc agtcatgagc tgagctgcat ttgcttgacc
     1921 aaatctcttt tcagttgtta aattctgttt ctgagaactg cttgggatgg ttggttcagg
     1981 tgagggtgct gcacacatga gggccaggag ctctgggctg ggcccctctg tgtgcttacc
     2041 acactgggaa ataatgcaac tcttgcagtt tccttgaaaa ctgaaagatt acgataaagt
     2101 tagatcatat ttctctggaa atgatcagcc ccacagccct ggaggtgctg cctcgttggt
     2161 cttggaggcc atgggagtcg tccccaaact cctcagaaac ccgcagagtc actgtctacc
     2221 ctgtgagaaa gtgcgggtgc ttgttgtaac aagaatcatt actttagcca gcagtagtgg
     2281 gtggtggtgc cacacacctt agtcacagca ctcaggaagc agaggcaggc agctctcttg
     2341 aatttgagac cagcctggtc tacagagcta gctccaggac ataacataca tctctgctac
     2401 acagagaatc ccttattttg aaaaacaaag catatcatta ttttaaaata gaattgcctt
     2461 tttctcacat tgtctctctc tctgtttctg tctgtctctt tctctccctc tcaccttctc
     2521 tctctctctc tttctttctt tctttctttc tttctttctt tctttctttc tttctttctt
     2581 tctttctttc tttctttctt gttgtttttt gtttcttttt tttttttttc cagacaaggt
     2641 ttctttatgt agccctggct attctggaac tcagttatct acctgcctct gcctctgctt
     2701 ctaaagtgct gggattaaag atatgcactg ccactgccca gcaatacatt gtcattcttt
     2761 agatggggaa aaaaaggaaa aagaaacact gtgggctagc tagtttacac tagaaatttt
     2821 tgaggtgaac actggttaaa ggggttagta gctttcaata aacattgatt ttcctcatga
     2881 tagaagtgaa aataggaccc aaaggccaga caggaaagag tacgatggga tttcatgcac
     2941 gagaaaaggt tatgtgggat gaggttgggc cttgagtgtg ggagcagcag cagagtctga
     3001 gctaggcaag gtctctgggc cagtgctctt gaaggtttgt tttggcactc aggtcccctg
     3061 ccttggtgtt aaaaggggat agagtagctg ttaggacagc tgagacctca tcacgatccc
     3121 aggcctctag atacctgtgt gacccagttt tcccacagga agctacttct gtgtgtggtg
     3181 ttaggtgtgt ggggtgcaaa gcatggcagc tcattagtca ttagagtgga ggcaccgagc
     3241 tgattcctag gcaaagatga gacttgaaaa ctcagaatgg taatgtggac aggaaggttt
     3301 cagcaggtcc cagagtggtc ggacacacag cttttgagta tggttctctc agtagacttt
     3361 tagactttgc caccatccct atcctgctct gctcgtgcct tggcctggag atggcatcca
     3421 ggaccatgtc tccaggaaag gtgcagagca tccttagaag cccgctagat acctgacagg
     3481 tagcttatat agtagcgcct ggtctttcag aggttctcat tacttcctgt ctggtactca
     3541 aggggcagca ccctgtggga gttgctttag atcccttgaa ctgaagggat gagtggggcc
     3601 taggattgct atcttccctg cagtttttag gggcagcagc tcagtggata cagtaaggcc
     3661 ggctgctgct agtgatcttt ccagtaccat gaaaactact cagttaagca gaagggacct
     3721 gctgtcctgt acagatcctc tgcaggggat tctaggaatg aaggacacat ccaggcttct
     3781 ctgcacctct gttcacctgt gtgcagatgc taaactgttt ggccaagtgt gacagccaag
     3841 gacagcagag ttccgagggg aggggggggg cccttagggt ggggtgctaa ctgttaagct
     3901 acctggtctt aggacagacc acctgccttc cttcctgctc actaggacta gagaatgttg
     3961 cccaggattc cctgaggatt cctctccaga gccttcactg tactcagaag catggggagg
     4021 gcagtctctg tgaccacttg gcccgttctg ggtttttcta tgtattccct agctcaccct
     4081 gaccttccag gttaggtgtt tccatgagag gactggggac ttctgttttc acatgtgatc
     4141 ttaggtgggg gatttccagc cccagtccta ttccctgcac ttatttttat ttaaacagac
     4201 tgtctgtcta tataacccag actagcatgg aattcacagc catcgtgttt tagtctcctg
     4261 aaaactggga ttacaggtgt acaccactat gcatagctag catgtaaatt cccagttagt
     4321 ttgggaattg ataattatgt catatcacag cttaaatgtg tagtaaaggc actgccccct
     4381 gctaactcat ttcctccttc agtgcagtgg tttgagtgta agaaaagaag gcccgcgttg
     4441 agctcactga cacacacctg tcgtcgcagc atttgggagg tggaggcagg aagatggggg
     4501 gtacaaggtc atcgagatgg ttcactcagt agaactactt gccacaaccc aaatttggtc
     4561 ctcagtatca acaccatgca gctcacaact gcctataatc tagctctagg gggatcagac
     4621 atctctggcc tcctagggcc acgtgtaagt cccctccccc aacatacaca cacacacaca
     4681 cacacacaca cagagttaaa aataaatctc tttttaaaaa tctaagcatg ggctacagaa
     4741 tgagttcaaa tgttagcctg ggcaacttag tgaaactgtt aaaagaaaac atgaagagag
     4801 ctgtggctct agctcagtgg tcgaacgctg cccagcaagt aaaacgctta ggctcttagc
     4861 attataaaaa aggaaggaga ataaatccac tggcacggag agatggctaa gtagttaagc
     4921 ttgtactgct ctcttgggtg tttttgtttt tgagacaaag tctctcttat acaatctggc
     4981 tgccctgaga cttaactatg tagactgggc agagctgcct gcttccatct cctgagtact
     5041 ggctttaaag aagtgtactg ccatgcccag tggtaagagc atgcgttctt gcagagaacc
     5101 aaagttcagt ttccagcact catgatggtg gttcaccact gcctataact ctagctcttc
     5161 tgacttccct gggcattata cttaccatac atataccctt ccccctcaaa aaagaaataa
     5221 aattaaaaat aaattttttt cttaaaaaaa aaaaa
//
