LOCUS       NM_022324               1118 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus stromal cell-derived factor 2-like 1 (Sdf2l1), mRNA.
ACCESSION   NM_022324
VERSION     NM_022324.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1118)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1118)
  AUTHORS   Sasako,T., Ohsugi,M., Kubota,N., Itoh,S., Okazaki,Y., Terai,A.,
            Kubota,T., Yamashita,S., Nakatsukasa,K., Kamura,T., Iwayama,K.,
            Tokuyama,K., Kiyonari,H., Furuta,Y., Shibahara,J., Fukayama,M.,
            Enooku,K., Okushin,K., Tsutsumi,T., Tateishi,R., Tobe,K.,
            Asahara,H., Koike,K., Kadowaki,T. and Ueki,K.
  TITLE     Hepatic Sdf2l1 controls feeding-induced ER stress and regulates
            metabolism
  JOURNAL   Nat Commun 10 (1), 947 (2019)
   PUBMED   30814508
  REMARK    GeneRIF: In obese and diabetic mice, Sdf2l1 is downregulated due to
            decreased levels of nuclear XBP-1s, whereas restoration of Sdf2l1
            expression ameliorates glucose intolerance and fatty liver with
            decreased ER stress.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1118)
  AUTHORS   Pehrson,J.R., Changolkar,L.N., Costanzi,C. and Leu,N.A.
  TITLE     Mice without macroH2A histone variants
  JOURNAL   Mol Cell Biol 34 (24), 4523-4533 (2014)
   PUBMED   25312643
REFERENCE   4  (bases 1 to 1118)
  AUTHORS   Patra,D., DeLassus,E., Liang,G. and Sandell,L.J.
  TITLE     Cartilage-specific ablation of site-1 protease in mice results in
            the endoplasmic reticulum entrapment of type IIb procollagen and
            down-regulation of cholesterol and lipid homeostasis
  JOURNAL   PLoS One 9 (8), e105674 (2014)
   PUBMED   25147951
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1118)
  AUTHORS   Tiwari,A., Schuiki,I., Zhang,L., Allister,E.M., Wheeler,M.B. and
            Volchuk,A.
  TITLE     SDF2L1 interacts with the ER-associated degradation machinery and
            retards the degradation of mutant proinsulin in pancreatic
            beta-cells
  JOURNAL   J Cell Sci 126 (Pt 9), 1962-1968 (2013)
   PUBMED   23444373
REFERENCE   6  (bases 1 to 1118)
  AUTHORS   Meunier,L., Usherwood,Y.K., Chung,K.T. and Hendershot,L.M.
  TITLE     A subset of chaperones and folding enzymes form multiprotein
            complexes in endoplasmic reticulum to bind nascent proteins
  JOURNAL   Mol Biol Cell 13 (12), 4456-4469 (2002)
   PUBMED   12475965
REFERENCE   7  (bases 1 to 1118)
  AUTHORS   Shirotani,K., Tsubuki,S., Iwata,N., Takaki,Y., Harigaya,W.,
            Maruyama,K., Kiryu-Seo,S., Kiyama,H., Iwata,H., Tomita,T.,
            Iwatsubo,T. and Saido,T.C.
  TITLE     Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most
            rapidly and efficiently among thiorphan- and
            phosphoramidon-sensitive endopeptidases
  JOURNAL   J Biol Chem 276 (24), 21895-21901 (2001)
   PUBMED   11278416
REFERENCE   8  (bases 1 to 1118)
  AUTHORS   Fukuda,S., Sumii,M., Masuda,Y., Takahashi,M., Koike,N.,
            Teishima,J., Yasumoto,H., Itamoto,T., Asahara,T., Dohi,K. and
            Kamiya,K.
  TITLE     Murine and human SDF2L1 is an endoplasmic reticulum
            stress-inducible gene and encodes a new member of the Pmt/rt
            protein family
  JOURNAL   Biochem Biophys Res Commun 280 (1), 407-414 (2001)
   PUBMED   11162531
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY253823.1 and BC053425.1.
            
            On Oct 25, 2007 this sequence version replaced NM_022324.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053425.1, AB043006.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-296               BY253823.1         2-297
            297-1118            BC053425.1         279-1100
FEATURES             Location/Qualifiers
     source          1..1118
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 10.62 cM"
     gene            1..1118
                     /gene="Sdf2l1"
                     /note="stromal cell-derived factor 2-like 1"
                     /db_xref="GeneID:64136"
                     /db_xref="MGI:MGI:2149842"
     exon            1..260
                     /gene="Sdf2l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..739
                     /gene="Sdf2l1"
                     /note="stromal cell-derived factor 2-like protein 1;
                     SDF2-like protein 1"
                     /codon_start=1
                     /product="stromal cell-derived factor 2-like protein 1
                     precursor"
                     /protein_id="NP_071719.1"
                     /db_xref="CCDS:CCDS37270.1"
                     /db_xref="GeneID:64136"
                     /db_xref="MGI:MGI:2149842"
                     /translation="MWGASRGRVAGPTLLGLLLALSVRSGGASKASAGLVTCGSVLKL
                     LNTHHKVRLHSHDIKYGSGSGQQSVTGVEESDDANSYWRIRGGSEGGCPRGLPVRCGQ
                     AVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREASV
                     RFQHVGTSVFLSVTGEQYGNPIRGQHEVHGMPSANAHNTWKAMEGIFIKPGADLSTGH
                     DEL"
     exon            261..457
                     /gene="Sdf2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            458..1108
                     /gene="Sdf2l1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1086..1091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdf2l1"
                     /note="hexamer: AATAAA"
     polyA_site      1108
                     /gene="Sdf2l1"
                     /note="major polyA site"
ORIGIN      
        1 agagctggat tggccgctgt tgaggacgga agcgcagagg tctagagcag ctggaacctg
       61 gccggctggc gggatgtggg gcgcgagccg gggcagggta gcggggccaa cgctgctggg
      121 gctgctgctg gcgctctcag tgcggagtgg gggcgcgtcc aaggccagcg ccgggctagt
      181 gacctgcggg tcagtgctga agctgctcaa cacccaccac aaagtgcggc tgcactcaca
      241 cgacatcaaa tacggatctg gcagcggcca acagtcggta accggcgtgg aggagtccga
      301 cgatgccaat agttactggc ggattcgcgg cggctccgag ggtgggtgcc cgcgcggact
      361 cccagtgcgc tgtgggcaag cagtgcggct cacgcacgtg ctcaccggca agaacctgca
      421 cacgcaccac ttcccgtcgc cgctatccaa caaccaggag gtgagtgctt ttggggaaga
      481 cggtgagggt gatgacctgg acctgtggac agtccgatgt tctgggcaac actgggagcg
      541 agaggccagt gtccgcttcc agcacgtggg cacctctgtg ttcctgtcgg tcactggtga
      601 acagtatggt aaccccatcc gtgggcagca tgaggttcat ggcatgccta gtgccaatgc
      661 tcacaacacg tggaaggcaa tggaaggaat cttcatcaag cctggagcag atctctccac
      721 gggtcacgat gaactctgag aaccagatga gtgatgggag ggtggctgag tggcaatctc
      781 ggggtcactc ttgtgtaaga ctttgtttgt aggggccctc aagtgccttt atgattaaag
      841 aatgttggtc tgggattatt tttgctgtaa ccctggggaa gatctgaagg tgccagccat
      901 atctgtccaa gttaccatct cacctgtctc aagcacctgc tgaaattttt tttttttttt
      961 ttttttgaga ctgtctcact atgtatcctt ggcaggcctg gaactcacag agagatccac
     1021 ctgcctctgt ctcctgagtg ctggtattaa aggtgtacac caccacaact ggccccaacc
     1081 tgttcaataa actcattttt attactaaaa aaaaaaaa
//
