LOCUS       NM_001404343            1136 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus stromal cell derived factor 2 (Sdf2), transcript
            variant 7, mRNA.
ACCESSION   NM_001404343 XM_030245720
VERSION     NM_001404343.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Lorenzon-Ojea,A.R., Caldeira,W., Ribeiro,A.F., Fisher,S.J.,
            Guzzo,C.R. and Bevilacqua,E.
  TITLE     Stromal cell derived factor-2 (Sdf2): a novel protein expressed in
            mouse
  JOURNAL   Int J Biochem Cell Biol 53, 262-270 (2014)
   PUBMED   24878610
  REMARK    GeneRIF: Comparing the amino acid sequence and predicted 3D
            structure with other Sdf2-like proteins we suggest a role of mouse
            Sdf2 in the Unfolded Protein Response and ER-stress, similar to
            that of Sdf2l1 from human and mouse and SDF2-like from Arabidopsis
REFERENCE   2  (bases 1 to 1136)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 1136)
  AUTHORS   Carramolino,L., Lee,B.C., Zaballos,A., Peled,A., Barthelemy,I.,
            Shav-Tal,Y., Prieto,I., Carmi,P., Gothelf,Y., Gonzalez de
            Buitrago,G., Aracil,M., Marquez,G., Barbero,J.L. and Zipori,D.
  TITLE     SA-1, a nuclear protein encoded by one member of a novel gene
            family: molecular cloning and detection in hemopoietic organs
  JOURNAL   Gene 195 (2), 151-159 (1997)
   PUBMED   9305759
  REMARK    Erratum:[Gene 1998 Jan 12;206(2):283]
REFERENCE   4  (bases 1 to 1136)
  AUTHORS   Shirozu,M., Tada,H., Tashiro,K., Nakamura,T., Lopez,N.D.,
            Nazarea,M., Hamada,T., Sato,T., Nakano,T. and Honjo,T.
  TITLE     Characterization of novel secreted and membrane proteins isolated
            by the signal sequence trap method
  JOURNAL   Genomics 37 (3), 273-280 (1996)
   PUBMED   8938438
REFERENCE   5  (bases 1 to 1136)
  AUTHORS   Hamada,T., Tashiro,K., Tada,H., Inazawa,J., Shirozu,M.,
            Shibahara,K., Nakamura,T., Martina,N., Nakano,T. and Honjo,T.
  TITLE     Isolation and characterization of a novel secretory protein,
            stromal cell-derived factor-2 (SDF-2) using the signal sequence
            trap method
  JOURNAL   Gene 176 (1-2), 211-214 (1996)
   PUBMED   8918255
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591070.19.
            
            On Apr 9, 2022 this sequence version replaced XM_030245720.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784647.1302894.1,
                                           SRR17253012.10130498.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-180               AL591070.19        103820-103999       c
            181-305             AL591070.19        99445-99569         c
            306-502             AL591070.19        98778-98974         c
            503-1136            AL591070.19        94506-95139         c
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..1136
                     /gene="Sdf2"
                     /note="stromal cell derived factor 2"
                     /db_xref="GeneID:20316"
                     /db_xref="MGI:MGI:108019"
     exon            1..180
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     exon            181..305
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             263..790
                     /gene="Sdf2"
                     /note="isoform 7 is encoded by transcript variant 7"
                     /codon_start=1
                     /product="stromal cell-derived factor 2 isoform 7"
                     /protein_id="NP_001391272.1"
                     /db_xref="GeneID:20316"
                     /db_xref="MGI:MGI:108019"
                     /translation="MKIHKWLSQDILFHSSGQQSVTGVTSVDDSNSYWRIRGKTATVC
                     ERGTPIKCGQPIRLTHINTGRNLHSHHFTSPLSGNQEVSAFGEEGEGDYLDDWTVLCN
                     GPYWVRDGEVRFKHSSTDVLLSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEGIFM
                     KPSELLRAEVHHAEL"
     exon            306..502
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     exon            503..1136
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1129..1134
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdf2"
                     /note="hexamer: AATAAA"
     polyA_site      1136
                     /gene="Sdf2"
                     /note="major polyA site"
ORIGIN      
        1 cttggatgat tagttctctc ggatctagga tggctgtctt gtcgcttctg ttgttgggtg
       61 gtttgtggag cgctgtggga gcgtccaaca tggctgtcgt tacttgcggc tccgtggtga
      121 agctactcaa tacacgccac aatgtccgac tgcattctca cgacgtgcgc tatgggtcag
      181 catcttgtct cgtgatttgg ctgaattcat cacagctaca gaggatcgaa ttcatgtgct
      241 tgtccaaggc cttaaaggtt caatgaagat tcacaaatgg ctctcacagg acatcttatt
      301 ccatagtagt gggcagcagt cagtgacagg tgtgacctct gtggatgaca gcaacagtta
      361 ctggaggata cgggggaaga cagccacagt gtgtgaaagg ggaaccccca tcaaatgcgg
      421 gcagcccatc cgtctgacac acatcaacac aggtcgaaac ctgcacagcc accatttcac
      481 ttcacctctc tctggaaacc aggaagtgag tgcctttggc gaagaaggtg aaggcgacta
      541 tctggatgac tggacagtgc tctgtaatgg accttactgg gttagagatg gtgaggtgag
      601 gttcaaacat tcttccactg acgtactgct gtctgtcaca ggagaacagt acggacgacc
      661 cataagtgga caaaaagagg tacatggtat ggcccagcca agtcagaaca actactggaa
      721 ggccatggaa ggcatcttca tgaagcccag tgagttgctg agggcagagg tccatcatgc
      781 agagctgtga ctctaaatac tctgagccac tgtcgccaca cagtgtttgt agacatctgc
      841 tgctgcttta ctgcgggatc cctgctccag gtcctctgag cgtgctgcct tgggacctgc
      901 agcccttcac acttgaattg gttgctctcc caggcttagt cagttctctc gggaaaggac
      961 tcactcgtct gtgaaggtgg agatagcttt cttcatgctg gtaaaagaag ttgaggagct
     1021 tgcctgtctt agctgggaag tgtaactccg caggaactgg gcatcatgga ttcttaattt
     1081 gtgatttctc ctgttttgtc tttctccaaa ataatgaata aataaataaa taaaaa
//
