LOCUS       NM_001404339            1093 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus stromal cell derived factor 2 (Sdf2), transcript
            variant 4, mRNA.
ACCESSION   NM_001404339
VERSION     NM_001404339.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Lorenzon-Ojea,A.R., Caldeira,W., Ribeiro,A.F., Fisher,S.J.,
            Guzzo,C.R. and Bevilacqua,E.
  TITLE     Stromal cell derived factor-2 (Sdf2): a novel protein expressed in
            mouse
  JOURNAL   Int J Biochem Cell Biol 53, 262-270 (2014)
   PUBMED   24878610
  REMARK    GeneRIF: Comparing the amino acid sequence and predicted 3D
            structure with other Sdf2-like proteins we suggest a role of mouse
            Sdf2 in the Unfolded Protein Response and ER-stress, similar to
            that of Sdf2l1 from human and mouse and SDF2-like from Arabidopsis
REFERENCE   2  (bases 1 to 1093)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 1093)
  AUTHORS   Carramolino,L., Lee,B.C., Zaballos,A., Peled,A., Barthelemy,I.,
            Shav-Tal,Y., Prieto,I., Carmi,P., Gothelf,Y., Gonzalez de
            Buitrago,G., Aracil,M., Marquez,G., Barbero,J.L. and Zipori,D.
  TITLE     SA-1, a nuclear protein encoded by one member of a novel gene
            family: molecular cloning and detection in hemopoietic organs
  JOURNAL   Gene 195 (2), 151-159 (1997)
   PUBMED   9305759
  REMARK    Erratum:[Gene 1998 Jan 12;206(2):283]
REFERENCE   4  (bases 1 to 1093)
  AUTHORS   Shirozu,M., Tada,H., Tashiro,K., Nakamura,T., Lopez,N.D.,
            Nazarea,M., Hamada,T., Sato,T., Nakano,T. and Honjo,T.
  TITLE     Characterization of novel secreted and membrane proteins isolated
            by the signal sequence trap method
  JOURNAL   Genomics 37 (3), 273-280 (1996)
   PUBMED   8938438
REFERENCE   5  (bases 1 to 1093)
  AUTHORS   Hamada,T., Tashiro,K., Tada,H., Inazawa,J., Shirozu,M.,
            Shibahara,K., Nakamura,T., Martina,N., Nakano,T. and Honjo,T.
  TITLE     Isolation and characterization of a novel secretory protein,
            stromal cell-derived factor-2 (SDF-2) using the signal sequence
            trap method
  JOURNAL   Gene 176 (1-2), 211-214 (1996)
   PUBMED   8918255
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591070.19.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR15390195.182184.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                AL591070.19        101833-101917       c
            86-137              AL591070.19        99657-99708         c
            138-262             AL591070.19        99445-99569         c
            263-459             AL591070.19        98778-98974         c
            460-1093            AL591070.19        94506-95139         c
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..1093
                     /gene="Sdf2"
                     /note="stromal cell derived factor 2"
                     /db_xref="GeneID:20316"
                     /db_xref="MGI:MGI:108019"
     exon            1..85
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..747
                     /gene="Sdf2"
                     /note="isoform 4 is encoded by transcript variant 4"
                     /codon_start=1
                     /product="stromal cell-derived factor 2 isoform 4"
                     /protein_id="NP_001391268.1"
                     /db_xref="GeneID:20316"
                     /db_xref="MGI:MGI:108019"
                     /translation="MEGPGVAMRTQVEQSGADEAQVTESPAGGVRSIQVSSIFRSILS
                     RDLAEFITATEDRIHVLVQGLKGSMKIHKWLSQDILFHSSGQQSVTGVTSVDDSNSYW
                     RIRGKTATVCERGTPIKCGQPIRLTHINTGRNLHSHHFTSPLSGNQEVSAFGEEGEGD
                     YLDDWTVLCNGPYWVRDGEVRFKHSSTDVLLSVTGEQYGRPISGQKEVHGMAQPSQNN
                     YWKAMEGIFMKPSELLRAEVHHAEL"
     exon            86..137
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     exon            138..262
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     exon            263..459
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     exon            460..1093
                     /gene="Sdf2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1086..1091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdf2"
                     /note="hexamer: AATAAA"
     polyA_site      1093
                     /gene="Sdf2"
                     /note="major polyA site"
ORIGIN      
        1 agaagaaaag aagatatgga gggaccagga gtggccatga gaacacaggt ggagcagagt
       61 ggggctgatg aggctcaggt cacagaatcc ccagcaggag gagtaaggag catccaagta
      121 tccagtatct ttagaagcat cttgtctcgt gatttggctg aattcatcac agctacagag
      181 gatcgaattc atgtgcttgt ccaaggcctt aaaggttcaa tgaagattca caaatggctc
      241 tcacaggaca tcttattcca tagtagtggg cagcagtcag tgacaggtgt gacctctgtg
      301 gatgacagca acagttactg gaggatacgg gggaagacag ccacagtgtg tgaaagggga
      361 acccccatca aatgcgggca gcccatccgt ctgacacaca tcaacacagg tcgaaacctg
      421 cacagccacc atttcacttc acctctctct ggaaaccagg aagtgagtgc ctttggcgaa
      481 gaaggtgaag gcgactatct ggatgactgg acagtgctct gtaatggacc ttactgggtt
      541 agagatggtg aggtgaggtt caaacattct tccactgacg tactgctgtc tgtcacagga
      601 gaacagtacg gacgacccat aagtggacaa aaagaggtac atggtatggc ccagccaagt
      661 cagaacaact actggaaggc catggaaggc atcttcatga agcccagtga gttgctgagg
      721 gcagaggtcc atcatgcaga gctgtgactc taaatactct gagccactgt cgccacacag
      781 tgtttgtaga catctgctgc tgctttactg cgggatccct gctccaggtc ctctgagcgt
      841 gctgccttgg gacctgcagc ccttcacact tgaattggtt gctctcccag gcttagtcag
      901 ttctctcggg aaaggactca ctcgtctgtg aaggtggaga tagctttctt catgctggta
      961 aaagaagttg aggagcttgc ctgtcttagc tgggaagtgt aactccgcag gaactgggca
     1021 tcatggattc ttaatttgtg atttctcctg ttttgtcttt ctccaaaata atgaataaat
     1081 aaataaataa aaa
//
