LOCUS       NM_001098227            2553 bp    mRNA    linear   ROD 14-AUG-2023
DEFINITION  Mus musculus syndecan binding protein (Sdcbp), transcript variant
            1, mRNA.
ACCESSION   NM_001098227
VERSION     NM_001098227.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2553)
  AUTHORS   Liu J, Bai W, Zhou T, Xie Y, Yang B, Sun J, Wang Y, Li X, Hou X,
            Liu Z, Fu D, Yan J, Jiang W, Zhao K, Zhou B, Yuan S, Guo Y, Wang H,
            Chang A, Gao S, Shi L, Huang C, Yang S and Hao J.
  TITLE     SDCBP promotes pancreatic cancer progression by preventing YAP1
            from beta-TrCP-mediated proteasomal degradation
  JOURNAL   Gut 72 (9), 1722-1737 (2023)
   PUBMED   36828627
  REMARK    GeneRIF: SDCBP promotes pancreatic cancer progression by preventing
            YAP1 from beta-TrCP-mediated proteasomal degradation.
REFERENCE   2  (bases 1 to 2553)
  AUTHORS   Jahodova I, Baliova M and Jursky F.
  TITLE     PDZ interaction of the GABA transporter GAT1 with the syntenin-1 in
            Neuro-2a cells
  JOURNAL   Neurochem Int 165, 105522 (2023)
   PUBMED   36966820
  REMARK    GeneRIF: PDZ interaction of the GABA transporter GAT1 with the
            syntenin-1 in Neuro-2a cells.
REFERENCE   3  (bases 1 to 2553)
  AUTHORS   Xu Z, Qiao S, Qian W, Zhu Y, Yan W, Shen S and Wang T.
  TITLE     Card9 protects fungal peritonitis through regulating Malt1-mediated
            activation of autophagy in macrophage
  JOURNAL   Int Immunopharmacol 110, 108941 (2022)
   PUBMED   35850054
REFERENCE   4  (bases 1 to 2553)
  AUTHORS   Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF,
            Zanivan S and Kalluri R.
  TITLE     Quantitative proteomics identifies the core proteome of exosomes
            with syntenin-1 as the highest abundant protein and a putative
            universal biomarker
  JOURNAL   Nat Cell Biol 23 (6), 631-641 (2021)
   PUBMED   34108659
  REMARK    GeneRIF: Quantitative proteomics identifies the core proteome of
            exosomes with syntenin-1 as the highest abundant protein and a
            putative universal biomarker.
REFERENCE   5  (bases 1 to 2553)
  AUTHORS   Kashyap R, Balzano M, Lechat B, Lambaerts K, Egea-Jimenez AL, Lembo
            F, Fares J, Meeussen S, Kugler S, Roebroek A, David G and
            Zimmermann P.
  TITLE     Syntenin-knock out reduces exosome turnover and viral transduction
  JOURNAL   Sci Rep 11 (1), 4083 (2021)
   PUBMED   33602969
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2553)
  AUTHORS   Araki K, Imaizumi T, Sekimoto T, Yoshinobu K, Yoshimuta J, Akizuki
            M, Miura K, Araki M and Yamamura K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   7  (bases 1 to 2553)
  AUTHORS   Fernandez-Larrea J, Merlos-Suarez A, Urena JM, Baselga J and
            Arribas J.
  TITLE     A role for a PDZ protein in the early secretory pathway for the
            targeting of proTGF-alpha to the cell surface
  JOURNAL   Mol Cell 3 (4), 423-433 (1999)
   PUBMED   10230395
REFERENCE   8  (bases 1 to 2553)
  AUTHORS   Lin D, Gish GD, Songyang Z and Pawson T.
  TITLE     The carboxyl terminus of B class ephrins constitutes a PDZ domain
            binding motif
  JOURNAL   J Biol Chem 274 (6), 3726-3733 (1999)
   PUBMED   9920925
REFERENCE   9  (bases 1 to 2553)
  AUTHORS   Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL,
            Bredt DS, Gale NW and Yancopoulos GD.
  TITLE     PDZ proteins bind, cluster, and synaptically colocalize with Eph
            receptors and their ephrin ligands
  JOURNAL   Neuron 21 (6), 1453-1463 (1998)
   PUBMED   9883737
REFERENCE   10 (bases 1 to 2553)
  AUTHORS   Grootjans JJ, Zimmermann P, Reekmans G, Smets A, Degeest G, Durr J
            and David G.
  TITLE     Syntenin, a PDZ protein that binds syndecan cytoplasmic domains
  JOURNAL   Proc Natl Acad Sci U S A 94 (25), 13683-13688 (1997)
   PUBMED   9391086
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY779386.1, AK150278.1, BY757323.1, W65143.1, BB736053.1 and
            BY387130.1.
            
            [WARNING] On Oct 18, 2023 this sequence was replaced by
            NM_001098227.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028429.1, AK033412.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                BY779386.1         2-38
            38-1628             AK150278.1         3-1593
            1629-2090           BY757323.1         214-675
            2091-2156           W65143.1           231-296
            2157-2545           BB736053.1         17-405
            2546-2553           BY387130.1         353-360
FEATURES             Location/Qualifiers
     source          1..2553
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 2.91 cM"
     gene            1..2553
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /note="syndecan binding protein"
                     /db_xref="GeneID:53378"
                     /db_xref="MGI:MGI:1337026"
     exon            1..80
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            81..146
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            147..228
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            229..338
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            339..500
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            501..676
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            677..848
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            849..940
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            941..2553
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1614..1619
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /note="putative"
     polyA_site      1628
                     /gene="Sdcbp"
                     /gene_synonym="MDA-9; Sycl; syntenin-1"
                     /note="putative"
ORIGIN      
        1 gatgacgcgc agggcgggcc ccgaggttcg gttgtgtgga gctggagcgg gcagcaggag
       61 cggcgcggtc ctcggggcag aaaatatctg cagaaatgtc tctttatcca tctcttgaag
      121 atttgaaggt agacaaagta attcaggctc aaactgctta ttctgccaat cccgccagcc
      181 aagcatttgt tctggtggat gcttctgctg ctctccctcc agatggaaat ctgtatccta
      241 aactgtatcc agagctctct caatacatgg gactgtcttt aaatgaagct gaaatatgtg
      301 agagcatgcc catggtctct ggagcaccag cacaagggca gttggtagca agaccatcca
      361 gtgtgaacta tatggtagca cctgtgacag gtaacgatgc tggaattcgg agagcagaaa
      421 ttaagcaagg gatccgtgaa gttattttgt gtaaggatca agatggaaaa attgggctca
      481 gacttaagtc aatagataat ggtatatttg ttcaactcgt ccaggctaat tccccagcct
      541 ccttggttgg actgagattt ggggaccagg tgctccagat caacggtgaa aactgtgcgg
      601 gctggagctc tgataaggca cacaaggtgc tcaagcaggc gtttggagag aagatcacca
      661 tgacgatccg tgacaggccc tttgaacgga cagttactat gcataaggac agcagtggac
      721 atgttggctt tatctttaaa agtggaaaaa tcacatccat agtaaaagat agttctgctg
      781 ccagaaacgg cctcctcact gatcaccaca tctgtgagat caacggacag aacgtcattg
      841 gcttgaagga tgctcagatt gcagatatac tgtcaacagc tgggactgtg gttaccatca
      901 caatcatgcc tacttttatc ttcgaacaca ttattaaacg gatggctccc agcattatga
      961 aaagcctgat ggatcacacc attcctgaag tttaaaccct tgtacaatgc atcacggctg
     1021 aatgtttcca gttttcctct tcggcaactt gtctatttcg cacatgaagc tttcccggag
     1081 ccagggagaa tatgctgcat ggagaccttt ctctcttctc tcatagctgg gaacccgctc
     1141 tatctgatac tggcttcaga ttttaagatg ggtgtagcct tagcctggtt ttacagatgt
     1201 gagactccca aaagatttac tgactttcct agactgggtt ctttactggg aacctgatgt
     1261 ttttatataa gccattgtga ttaggatgac tggtataggc ttagctgtgt ctgagacctg
     1321 gtcagctttc tcctagaaca aagcacagtg ctagtcatgt gcttcaattc tgtggcattc
     1381 ttggacttta gtacgtcagc atagtacatt tagaatgatt gcctttgata gttatttttt
     1441 taagttttct ctgtgtgagt gtgtaaaatt ccaattaatc aacactgttt tcattccaca
     1501 aaagcattac acagttgtgt gtaggttgca agagactgta atgattgtca ctaatcttaa
     1561 ctaccttcac ttaatatgct tcaattgtcg ccttaactac agtaagcatt tagaataaaa
     1621 gccaaaatag aattattgct gccttctgaa acttgagatg ttagctctct attaagctgt
     1681 tctgtgctag ccctgagcag ctcactggta aagcagagct gcctacttgt atcaagattt
     1741 tctagtcact gcataaagga aacgcctaag agttgccgta ttgctttctg agaaacaaat
     1801 tgctatatat ttcatgtaaa agttgttata ctaaatagaa taaattttgg agtctctttt
     1861 tcactctagt gggtaatatc taatttggca tttgagtcct aacattatgt aactttagct
     1921 aggttggggt cgttttagaa tgtttcccta gtcatcttaa tttgttccat tttctgactc
     1981 tgtcctataa acaaaaatgg caatgacact ttatgatttt ttctttctta gcttgtgcct
     2041 atcctattat tttatgtgat attattaaat gtataaaaat gtgaaatttc cgtctgtctg
     2101 tgcctgcatc agtccttact gtgaggctaa cactaggttc tttaagaagc tttagcggag
     2161 actgcctgga aatacacttg ctgggcatcc ctcttggcca gcctgtggtt accttcaccc
     2221 tgcgcactga catcagtgaa ggaacctgga aaggctgctg cgtctccagt gaatcccgag
     2281 accatccaca tgtattagtg acacttaaaa ctaactcaag gttctactac tttagtctgg
     2341 tgccttttct ctataacatg tttatatcat gcttcctttt ctctataaca tgcttcagaa
     2401 aatttgtaat cttgtagttg ctggtcagag actgaatgta agaaaatcat tgcagtttct
     2461 atataggcta ccttgttgga aatttataat tctcagtttg attatccacc ttgctttctg
     2521 gacttggttc tgaatatagg tccaaaagaa atg
//
