LOCUS       NM_011520               4972 bp    mRNA    linear   ROD 12-SEP-2023
DEFINITION  Mus musculus syndecan 3 (Sdc3), mRNA.
ACCESSION   NM_011520
VERSION     NM_011520.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4972)
  AUTHORS   Watanabe H, Fukuda A, Ikeda N, Sato M, Hashimoto K and Miyamoto Y.
  TITLE     Syndecan-3 regulates the time of transition from cell cycle exit to
            initial differentiation stage in mouse cerebellar granule cell
            precursors
  JOURNAL   Brain Res 1807, 148317 (2023)
   PUBMED   36898477
  REMARK    GeneRIF: Syndecan-3 regulates the time of transition from cell
            cycle exit to initial differentiation stage in mouse cerebellar
            granule cell precursors.
REFERENCE   2  (bases 1 to 4972)
  AUTHORS   Wishart TFL and Lovicu FJ.
  TITLE     Spatiotemporal Localisation of Heparan Sulphate Proteoglycans
            throughout Mouse Lens Morphogenesis
  JOURNAL   Cells 12 (10), 1364 (2023)
   PUBMED   37408198
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4972)
  AUTHORS   Jones FK, Phillips AM, Jones AR and Pisconti A.
  TITLE     The INSR/AKT/mTOR pathway regulates the pace of myogenesis in a
            syndecan-3-dependent manner
  JOURNAL   Matrix Biol 113, 61-82 (2022)
   PUBMED   36152781
REFERENCE   4  (bases 1 to 4972)
  AUTHORS   Hudak A, Letoha A, Vizler C and Letoha T.
  TITLE     Syndecan-3 as a Novel Biomarker in Alzheimer's Disease
  JOURNAL   Int J Mol Sci 23 (6), 3407 (2022)
   PUBMED   35328830
  REMARK    GeneRIF: Syndecan-3 as a Novel Biomarker in Alzheimer's Disease.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4972)
  AUTHORS   Johnson de Sousa Brito FM, Butcher A, Pisconti A, Poulet B, Prior
            A, Charlesworth G, Sperinck C, Scotto di Mase M, Liu K, Bou-Gharios
            G, Jurgen van 't Hof R and Daroszewska A.
  TITLE     Syndecan-3 enhances anabolic bone formation through WNT signaling
  JOURNAL   FASEB J 35 (4), e21246 (2021)
   PUBMED   33769615
  REMARK    GeneRIF: Syndecan-3 enhances anabolic bone formation through WNT
            signaling.
REFERENCE   6  (bases 1 to 4972)
  AUTHORS   Vihinen T, Maatta A, Jaakkola P, Auvinen P and Jalkanen M.
  TITLE     Functional characterization of mouse syndecan-1 promoter
  JOURNAL   J Biol Chem 271 (21), 12532-12541 (1996)
   PUBMED   8647862
REFERENCE   7  (bases 1 to 4972)
  AUTHORS   Kim CW, Goldberger OA, Gallo RL and Bernfield M.
  TITLE     Members of the syndecan family of heparan sulfate proteoglycans are
            expressed in distinct cell-, tissue-, and development-specific
            patterns
  JOURNAL   Mol Biol Cell 5 (7), 797-805 (1994)
   PUBMED   7812048
REFERENCE   8  (bases 1 to 4972)
  AUTHORS   Spring J, Goldberger OA, Jenkins NA, Gilbert DJ, Copeland NG and
            Bernfield M.
  TITLE     Mapping of the syndecan genes in the mouse: linkage with members of
            the myc gene family
  JOURNAL   Genomics 21 (3), 597-601 (1994)
   PUBMED   7959737
REFERENCE   9  (bases 1 to 4972)
  AUTHORS   Carey DJ, Evans DM, Stahl RC, Asundi VK, Conner KJ, Garbes P and
            Cizmeci-Smith G.
  TITLE     Molecular cloning and characterization of N-syndecan, a novel
            transmembrane heparan sulfate proteoglycan
  JOURNAL   J Cell Biol 117 (1), 191-201 (1992)
   PUBMED   1556152
REFERENCE   10 (bases 1 to 4972)
  AUTHORS   Sutherland AE, Sanderson RD, Mayes M, Seibert M, Calarco PG,
            Bernfield M and Damsky CH.
  TITLE     Expression of syndecan, a putative low affinity fibroblast growth
            factor receptor, in the early mouse embryo
  JOURNAL   Development 113 (1), 339-351 (1991)
   PUBMED   1765004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK129153.1.
            
            [WARNING] On Oct 16, 2023 this sequence was replaced by
            NM_011520.4.
            
            On Jul 15, 2006 this sequence version replaced NM_011520.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK129153.1, BC054795.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..4972
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 63.63 cM"
     gene            1..4972
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /note="syndecan 3"
                     /db_xref="GeneID:20970"
                     /db_xref="MGI:MGI:1349163"
     exon            1..266
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..1463
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /codon_start=1
                     /product="syndecan-3 precursor"
                     /protein_id="NP_035650.2"
                     /db_xref="CCDS:CCDS38894.1"
                     /db_xref="GeneID:20970"
                     /db_xref="MGI:MGI:1349163"
                     /translation="MKPGPPRRGTAQGQRVDTATHAPGARGLLLPPLLLLLLAGRAAG
                     AQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDMA
                     LAAPTAPAMLPTTVIQPVDTPFEELLSEHPSPEPVTSPPLVTEVTEVVEESSQKATTI
                     STTTSTTAATTTGAPTMATAPATAATTAPSTPEAPPATATVADVRTTGIQGMLPLPLT
                     TAATAKITTPAAPSPPTTVATLDTEAPTPRLVNTATSRPRALPRPVTTQEPDVAERST
                     LPLGTTAPGPTEMAQTPTPESLLTTIQDEPEVPVSGGPSGDFELQEETTQPDTANEVV
                     AVEGAAAKPSPPLGTLPKGARPGPGLHDNAIDSGSSAAQLPQKSILERKEVLVAVIVG
                     GVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA"
     exon            267..384
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /inference="alignment:Splign:2.1.0"
     exon            385..1007
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1296
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..4972
                     /gene="Sdc3"
                     /gene_synonym="mKIAA0468; syn-3; Synd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcgacgct tcctgcgggc gcggccgctg tgggcgcgga gccgcgagcg agcgaacgaa
       61 cgagcgaggc ggagccggcg gccgaggagc cgagcgcagg tcccgcgcag cccgcgccgc
      121 gaacaaaggc cgccatgaag cccgggccgc cgcgccgcgg gaccgcacag gggcagcgcg
      181 tggacaccgc cacccatgcg cccggggccc gcgggctgtt gctgccaccg ctgctgctgc
      241 tgctgctggc cggccgcgcc gcgggggctc aacgctggcg caatgagaac ttcgagaggc
      301 cggtggatct tgagggctca ggggatgacg actcgtttcc tgatgatgaa ctagacgacc
      361 tctactcggg gtcaggctct ggctacttcg agcaggagtc cggccttgag acggccatgc
      421 ggttcatccc tgatatggcc ctggctgcgc ccactgcacc tgccatgcta cccacaaccg
      481 ttatccagcc cgtggacacc ccatttgagg aactcctttc tgagcacccc agccctgaac
      541 cagtcaccag tcccccgctg gtgacagagg tgacagaggt cgtagaagag tccagccaga
      601 aagctaccac catctctacc accacatcta ccaccgcggc caccaccaca ggggccccaa
      661 ctatggccac agcacctgcc acagcagcca ccactgcccc tagcactccc gaggcgcccc
      721 ctgccacggc taccgtggct gacgtaagga ccaccggcat acaggggatg ctgcctcttc
      781 ccctgaccac agctgccaca gccaagatca ctaccccagc agcaccctca ccacccacta
      841 ctgtggctac cttggacaca gaggccccga cacctaggct ggtcaacaca gctacctcga
      901 ggccacgagc ccttcctcgg ccagtcacca cccaggagcc tgatgttgct gagaggagta
      961 ccctgccgtt ggggaccacg gctcctggac ccacggagat ggctcagacc ccaactccag
     1021 agtcccttct gaccaccatc caggatgagc cagaggtgcc agtaagtggg gggcccagcg
     1081 gggactttga gcttcaagaa gagaccacgc agccggacac ggccaatgag gtggtggctg
     1141 tggaaggagc cgcggccaag ccgtcacctc cactggggac actgcccaag ggtgcccgcc
     1201 caggccctgg cctccacgac aatgccatcg attcgggcag ctcggccgcc cagctccctc
     1261 agaagagcat actggagcgg aaggaggtgc tcgtagccgt gatcgtgggt ggggtggtgg
     1321 gcgccctctt cgctgccttc ctggtcacgc tgctcatcta ccgcatgaag aagaaggacg
     1381 aaggcagcta caccttggaa gaacccaagc aggcaagcgt cacgtaccag aaacctgaca
     1441 agcaggagga gttctacgct tagcagagcc acagtgcctc ctgcagcctc cactccgcct
     1501 cgcccagtcc ctggccccag cagcagccca ggcctgatcc tgggcctggg cctgggcctg
     1561 ggatggagcc tggccctgct tctttctgct caggctgcta gcgtaacaca gactgtccta
     1621 aggagcagag gtgctgccat ctgccccaga ctgtgtcctt atgacccctt ctttggtccc
     1681 attccctcca gcccggggct tcaggacctt gtgtcccatg gacaagagga aggaagccct
     1741 gggttgctgg ttgaaacagg ggcaggggca gggttaagat ggcccacagt gcttgctgat
     1801 gtcctcttct tgctccagag gccaccatgc tggcttctag aaccaataat acatggtaca
     1861 tctagccctc caattcaaaa tcacccagat gctgtggcct cgagctgctg tcccaaggcc
     1921 tctctcttga caggagggtg ccctttgtca ccagcctgag ctcatgatgg ggtcaccgcc
     1981 ccctccccct gccaaatgca caggtcccca ggctgcacct cttcctgcat tgcctcccag
     2041 ggaaagggct tccttcagtg tacagggcag ccagtggtaa gtgaggccag tctagcatcc
     2101 ctcctgagag gggatgccac atagcctccg tcaaccacta ctagaatcct aaaatgcatt
     2161 cacacaggag acaaaaacat acccagtcct gaccacccag ccagcgagac atcacacaga
     2221 tgcaccacct tcacgcagtg ctcagccatc ctgatgcttc tgctacatcg taggccactg
     2281 tcattgtcac cagtggcgac cacaccacct tcctcccaat ctattctctt tacacacatt
     2341 ggtcctgcat ctggctcctc taaccatcca ggtcactgag gaaggcagga ccgagttgta
     2401 ggcatcagcc catattgggt cccccagagt cactctattc cacttggtcc ccaccatgac
     2461 acctatacca gccacactga tgctgatccc agctgacgtc agtcacaagc ccacacagtt
     2521 aatgcaggct ctccctcccc cactgtggct catagagaag tttggggcta gcctccacca
     2581 gccaagtttg aagcaagaag ggagctaggg cctcccagga ccaaggcgct gtgtgggttg
     2641 tccctggtct ccatgtatct cctttctgct ctgagccagg agctgtctct gcctcccagg
     2701 acacgtgtct ccaaagtgcc tgtgagggtg ggctccgccc aggccctctg tgtcccctgc
     2761 cctgccctgg cctggtgagg ccaacctcag gcctacctac cctgggtcct ttctgtggac
     2821 acaactgacc aggcaacttg gcagttctgg ctatatccag atgaacccat agcccaccag
     2881 gctcatccca atgctatagg ctctgagaat cattgatggg gacaagggtg tcacaggcct
     2941 caagtctacc atcctgtctc tgttatcctt agaagtgggg ctatttcaga ggtatttaaa
     3001 atgtgggggg tcaccattct ctttgtgaaa gggccatgcc gaaggagctc tcagcaccaa
     3061 agggacacag cttgggtagt gactggccgg cacccctcca ccatctctca catgtcccag
     3121 gttcagtcag gtgaccacat ggtttctttc tgtttcattt taaagaatcc ctgacagcag
     3181 agttgggcag actgaagaac cacatctggg taatggacag gatctaggca gttggcacag
     3241 cttgtctttc tggggtgggg gtggaggggg tgtccccctg tcaggctctg ttctgtcttc
     3301 cagacctcca tgactccctt gatgggactt tagagttttg taagccagtc ggcctggtct
     3361 ttaagtgggg gggaaggaat gagaggcgtc ctaaacccat gagatgtgga ggagggagct
     3421 tggccaagat cttccctgca gcaggggctg ggtagggcgt agaggagagc cagtgtccca
     3481 gaccctccca ctcctccctg gtaagctgca gtcttgggga ctagagcttt ggaaagagag
     3541 gctcagcagc tgggcgaggc aacctccagg tactcagccc aaggggacac cacgaccagg
     3601 gcaggaggcc ccagcttctg tgttgggcta gggttcactt ctcacatctc agggtggctc
     3661 tggccctggg gctatgggtt tggcatcctg ataccagcat ccttaatgtg tcagcatctg
     3721 agagaagagg cagtgggtct taagtatggg gtccgggctc caaggccaac gcctaggctt
     3781 catggccatg gcgtttgacc tgaaggttaa tggtgtgagc agcccagata aactgggcta
     3841 gcctggtgag gccaggacga tttaagagaa ctcagttcca agggtgaact gaattcttcc
     3901 tagtgcaatg tgggtgcggg gttcccaccc tgccccagaa acagtgcggt acatacagag
     3961 cctgtccaaa ggagtccaga gacacctcag tgctcctggg aaggtattca ggacaccggc
     4021 ttgcctggag acacaatgca ttctgaatca gaggtggtga tgtgtcctgg acttctctgg
     4081 gccctggttt ccctagagag taagacatgc tggggccaga gcactgaaga gctaagcttc
     4141 atctctcttg ggggccagac tagggactct atgtgtaagg ttgattctcc ttgattgcca
     4201 gaggcatgtg ggtgacagcc aggactggct gagcagatct gcagcaagag cttaggatgc
     4261 tggggccaga ccccctgggc ttggcttagc tactcatcag gcctcctggc tggggctcga
     4321 gcttcagaga gcagagccaa cgctgctctc agggcagttg tggctccctg ggctgtcctg
     4381 gctttctcct gggatgtgcc tcccagcctt ggtgtctgta aatagaagcc cacactgtac
     4441 agatctacag agaggcccaa actgggctct ggtgtcacca tctgaggggc tgatggcctg
     4501 gcttccccca ggtgccctgt gggtgcttgg gtatgcctgg ccccggcgtg gtgaatgcat
     4561 gtaaatactt cgtagacagt gtggctccag agagccccct gagacagtgt cccccccacc
     4621 ttactggttc atcctctctc ctgtacagag ccctcccagc ccctgggcca ccaggatcag
     4681 gggttacctc ccttccccag acctttccta cccgttctct ccctataacc tgtttattaa
     4741 ccaaccctgt cctgagttca tggccaaaac ttaaataaga gaaggaggag agggtcagat
     4801 ggataaagat aaagatacca aggcctggtc catccttacc atgggcgctc gtacacccct
     4861 ggcttgggaa ggacagggct tgctttgttt tgttttctgt tagtttttgt tttttaacat
     4921 ttccctgtgc tgtgcccatt tataagagga aataaaatta agctgaaaga tg
//
