LOCUS       NM_001163772             540 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus secretory calcium-binding phosphoprotein
            proline-glutamine rich 1 (Scpppq1), mRNA.
ACCESSION   NM_001163772
VERSION     NM_001163772.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Fouillen,A., Dos Santos Neves,J., Mary,C., Castonguay,J.D.,
            Moffatt,P., Baron,C. and Nanci,A.
  TITLE     Interactions of AMTN, ODAM and SCPPPQ1 proteins of a specialized
            basal lamina that attaches epithelial cells to tooth mineral
  JOURNAL   Sci Rep 7, 46683 (2017)
   PUBMED   28436474
  REMARK    GeneRIF: Data suggest that amelotin (AMTN), odontogenic
            ameloblast-associated protein (ODAM) and secretory calcium-binding
            phosphoprotein proline-glutamine rich 1 (SCPPPQ1) participate in
            structuring an extracellular matrix with the distinctive capacity
            of attaching epithelial cells to mineralized surfaces.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  AUTHORS   Moffatt,P., Wazen,R.M., Dos Santos Neves,J. and Nanci,A.
  TITLE     Characterisation of secretory calcium-binding
            phosphoprotein-proline-glutamine-rich 1: a novel basal lamina
            component expressed at cell-tooth interfaces
  JOURNAL   Cell Tissue Res 358 (3), 843-855 (2014)
   PUBMED   25193156
  REMARK    GeneRIF: the gene, protein and pattern of expression of a related
            protein called secretory calcium-binding
            phosphoprotein-proline-glutamine-rich 1 (SCPPPQ1), is reported.
REFERENCE   3  (bases 1 to 540)
  AUTHORS   Kawasaki,K.
  TITLE     The SCPP gene repertoire in bony vertebrates and graded differences
            in mineralized tissues
  JOURNAL   Dev Genes Evol 219 (3), 147-157 (2009)
   PUBMED   19255778
REFERENCE   4  (bases 1 to 540)
  AUTHORS   Moffatt,P., Smith,C.E., Sooknanan,R., St-Arnaud,R. and Nanci,A.
  TITLE     Identification of secreted and membrane proteins in the rat incisor
            enamel organ using a signal-trap screening approach
  JOURNAL   Eur J Oral Sci 114 Suppl 1, 139-46 (2006)
   PUBMED   16674676
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EU642618.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU642618.1, HM015623.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849380 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 50.54 cM"
     gene            1..540
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /note="secretory calcium-binding phosphoprotein
                     proline-glutamine rich 1"
                     /db_xref="GeneID:100271704"
                     /db_xref="MGI:MGI:4937294"
     exon            1..50
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            51..121
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..337
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /codon_start=1
                     /product="secretory calcium-binding phosphoprotein
                     proline-glutamine-rich 1 precursor"
                     /protein_id="NP_001157244.1"
                     /db_xref="CCDS:CCDS51577.1"
                     /db_xref="GeneID:100271704"
                     /db_xref="MGI:MGI:4937294"
                     /translation="MQLFLLAALLSAAAALPIPLGQSGGSSSEQRFNLYAPQILPFFP
                     PFPLPQAPLIPIPFPFPFDPNQVLTPNQLLELITSILNQLQGFLGR"
     exon            122..154
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            155..223
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            224..262
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            263..289
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            290..319
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            320..331
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            332..367
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
     exon            368..524
                     /gene="Scpppq1"
                     /gene_synonym="Gm17660"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccacactg cttcccgaat ctgtcgctcc aaggaccatt tgaaacacag atcctccctt
       61 cagaatgcag cttttcctcc tggccgccct gctgagcgct gcagctgctc tgccaatccc
      121 tcttggacaa tccggaggaa gttccagtga acagagattt aacttgtacg caccacaaat
      181 cctgcctttc ttccctccgt ttccccttcc gcaggctcct ctgatcccga ttccctttcc
      241 cttccctttt gatccaaatc aggttctgac acctaatcag cttctggagt taatcacttc
      301 tattttgaac caactgcagg gcttccttgg gagataagct tcactactac atcagaaggc
      361 tcgcacagtg gtgcaggtgt ccaggttacc tgctctgttc tctgcagctt ggaacaacgg
      421 tcttaccatc ttgtagactc tatagaacgt cctgtgaaac atccaatacc acaggcaaat
      481 ctactatcta cagccataca atcttaataa aattctccct aaaaaaaaaa aaaaaaaaaa
//
