LOCUS       XM_011239391            8661 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus sodium channel, voltage-gated, type III,
            alpha (Scn3a), transcript variant X1, mRNA.
ACCESSION   XM_011239391
VERSION     XM_011239391.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000068.8) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_011239391.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8661
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="2"
     gene            1..8661
                     /gene="Scn3a"
                     /gene_synonym="Gm1000; Nav1.3"
                     /note="sodium channel, voltage-gated, type III, alpha;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 11 ESTs, 558 long SRA reads, 38
                     Proteins, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 17 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:20269"
                     /db_xref="MGI:MGI:98249"
     CDS             377..6367
                     /gene="Scn3a"
                     /gene_synonym="Gm1000; Nav1.3"
                     /codon_start=1
                     /product="sodium channel protein type 3 subunit alpha
                     isoform X1"
                     /protein_id="XP_011237693.1"
                     /db_xref="GeneID:20269"
                     /db_xref="MGI:MGI:98249"
                     /translation="MAQALLVPPGPESFRLFTRESLAAIEKRAAEEKAKKPKKEQDID
                     DENKPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYVSKKTFVVLNKGKAIFRF
                     SATSALYILTPLNPVRKIAIKILVHSLFSMLIMCTILTNCVFMTLSNPPDWTKNVEYT
                     FTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFSVIVMAYVTEFVSLGNVSALRTF
                     RVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNK
                     CLQWPPSDSAFEINTTSYFNGTMDSNGTFVNVTMSTFNWKDYIADDSHFYVLDGQKDP
                     LLCGNGSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDYWENLYQLT
                     LRAAGKTYMIFFVLVIFLGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLE
                     QLKKQQEEAQAVAAASAASRDFSGIGGLGELLESSSEASKLSSKSAKEWRNRRKKRRQ
                     REHLEGNHRPEGDRFPKSESEDSVKRRSFLFSLDGNPLSGDKKLCSPHQSLLSIRGSL
                     FSPRRNSKTSIFSFRGRAKDVGSENDFADDEHSTFEDSESRRDSLFVPHRPGERRNSN
                     VSQASMSSRMVPGLPANGKMHSTVDCNGVVSLVGGPSALTSPTGQLPPEGTTTETEVR
                     KRRLSSYQISMEMLEDSSGRQRAMSIASILTNTMEELEESRQKCPPCWYRFANVFLIW
                     DCCDSWLKVKHLVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLTVGNLV
                     FTGIFTAEMVLKIIAMDPYYYFQEGWNIFDGIIVSLSLMELGLANVEGLSVLRSFRLL
                     RVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCK
                     INEDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVFMLVMVIGN
                     LVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDYVKNKIRECFRKAF
                     FRKPKVIEIHEGNKIDSCMSNNTGVVEISKELNYLKDGNGTTSGVGTGSSVEKYVIDE
                     NDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESELEESKEKLNATSSSEGSTVD
                     VAPPREGEQAEIEPEEDLKPEACFTEGCIKKFPFCQVSTEEGKGKIWWNLRKTCYSIV
                     EHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVA
                     YGFQTYFTNAWCWLDFLIVDVSLVSLVANALGYSELGAIKSLRTLRALRPLRALSRFE
                     GMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNMTTGSMFDMSE
                     VNNFSDCQALGKQARWKNVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRDVKLQ
                     PVYEENLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYY
                     NAMKKLGSKKPQKPIPRPANKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQS
                     KYMTLVLSRINLVFIVLFTGEFLLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAEL
                     IEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMF
                     IYAIFGMSNFAYVKKEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPD
                     CDPDAIHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAE
                     PLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPM
                     VSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEDRFMASNPSKVSYEPITTTLKRKQ
                     EEVSAAIIQRNYRCYLLKQRLKNISNTYDKETIKGRIVLPIKGDMVIDKLNGNSTPEK
                     TDGSSSTTSPPSYDSVTKPDKEKFEKDKPEKESKGKEV"
ORIGIN      
        1 agtagatggc agtaacacgt tgaatgctgc cagctttttc tttttctttc tttttttttt
       61 ttttttttcc ttccagggcc gttttctgat atatgttggg tatcatagag tgaatctcag
      121 aacaggaagc ggaggcataa gcagaaagga ttctggaaag gtctctttgt tttcatatcc
      181 acagagaaag caagaaaaaa aaattgaatg taatttgcaa atccctgtgg cccaaatctg
      241 aagaactact gggggtggca cgttccattc taaccatctt ggatgctgtc ctttgttgag
      301 ctgtgattcc taaggctctc catcaggcaa ttcttatgca agaagctaaa cgtaattaaa
      361 tgtgcaggat gaaaagatgg cccaggcact gctggtaccc ccgggacctg agagcttccg
      421 ccttttcact cgagaatctc ttgctgctat cgaaaagcgt gctgcagaag agaaagccaa
      481 gaaacccaag aaagaacaag acattgacga tgagaacaag ccaaagccaa acagtgactt
      541 ggaagctggg aagaaccttc catttatcta tggagacatt cctccagaga tggtgtcgga
      601 gcctctggag gacctggacc cctactacgt cagtaagaaa acttttgtag tgttgaataa
      661 agggaaggca atttttcgat tcagtgccac ctccgccttg tatattttaa ctccactaaa
      721 ccccgttagg aaaattgcta ttaagatttt ggtacactct ttattcagca tgcttatcat
      781 gtgcactatt ttgaccaact gtgtatttat gacattgagc aatcctcctg actggacgaa
      841 gaatgtagag tacacattca ctgggatcta tacctttgag tcacttataa agatcttggc
      901 cagaggattc tgcttagaag atttcacatt tcttcgtgac ccatggaact ggctggattt
      961 cagtgtcatc gtgatggcgt atgtaacaga atttgtaagc ctaggcaatg tttcagctct
     1021 tcgaactttc agagtcttgc gagctctgaa aactatttct gtaattccag gtttaaagac
     1081 catcgtgggg gccctgatcc agtcggtgaa gaagctgtct gacgtcatga tactcactgt
     1141 gttctgtctg agcgtctttg ctctcatcgg gctgcagctc ttcatgggca acctgaggaa
     1201 taaatgcttg cagtggcctc caagcgattc tgcttttgag atcaacacta cttcctactt
     1261 caatggcaca atggactcaa atgggacatt tgttaatgta acaatgagca cattcaactg
     1321 gaaggactat atcgcagatg acagccactt ttatgttttg gatggacaaa aagatccttt
     1381 actttgtgga aatgggtccg atgcaggaca atgtccagaa gggtacatct gtgtgaaggc
     1441 tggacgaaac cccaactacg gttacacgag ctttgacaca tttagctggg ccttcttatc
     1501 gctgtttcga ctcatgactc aagactactg ggagaacctt taccagttga cattacgtgc
     1561 agctgggaaa acctacatga tctttttcgt cctggtaatt ttcttgggct cattttattt
     1621 ggtgaacttg atcctggctg tggtggccat ggcctatgag gaacaaaatc aggccacact
     1681 ggaggaggct gagcagaaag aggcggagtt tcagcagatg ttggagcagt tgaaaaagca
     1741 gcaagaggag gctcaggcgg tggcagctgc ctcagcagcg tccagagact tcagtgggat
     1801 aggagggtta ggagaacttc tggagagttc ttcagaagct tccaagttga gctccaagag
     1861 tgccaaggag tggaggaatc ggaggaagaa gaggagacag agggagcact tggagggaaa
     1921 ccacagaccc gaaggagaca ggtttcccaa gtcggaatca gaagacagcg tcaagcgaag
     1981 gagtttcctg ttctccctgg atgggaaccc gctgagcggc gacaagaagc tgtgctctcc
     2041 ccatcagtct ctcttgagta tccgtggctc cctgttttcc ccaagacgca atagcaaaac
     2101 gagcattttc agcttcagag gtcgggcgaa ggacgtgggg tctgagaatg actttgcgga
     2161 tgatgaacac agcacctttg aagatagcga gagcaggaga gactcactgt ttgtgccgca
     2221 cagacctgga gagcgacgca acagtaacgt tagtcaggcc agtatgtcat ccaggatggt
     2281 gccagggctt ccagccaatg ggaagatgca cagcactgtg gattgcaatg gtgtggtttc
     2341 cttggtgggt ggaccctcag ctcttacgtc acctactgga cagcttccgc cagagggtac
     2401 caccactgaa acagaagtca ggaagagaag gctaagttct taccagatct cgatggaaat
     2461 gctggaggat tcctctggga gacaaagagc catgagcata gccagtatcc tgaccaacac
     2521 gatggaggaa cttgaagaat ctagacagaa gtgtccacca tgctggtata gatttgccaa
     2581 tgtgtttttg atctgggact gttgtgattc atggttgaaa gtaaagcatc ttgtgaattt
     2641 gattgtgatg gatccatttg ttgacctggc catcaccatc tgcatcgtgt taaacacact
     2701 gttcatggcc atggagcact acccgatgac ggagcagttc agcagtgtgc tgacggtggg
     2761 aaacctggtc ttcaccggga tcttcacagc cgagatggtc ctgaaaatca tcgcaatgga
     2821 tccctattac tatttccaag agggctggaa tatctttgat ggaattattg ttagcctgag
     2881 tttaatggag cttggcctgg caaacgtgga ggggctgtcc gtgcttcggt ccttcagact
     2941 gctgcgagtc ttcaagttgg caaaatcctg gcccacactg aatatgctca ttaagatcat
     3001 cggcaactcg gtgggcgcac tgggcaacct gaccctggtg ctggccatca tcgtcttcat
     3061 ttttgccgtg gtcggcatgc agctgtttgg aaagagctac aaggagtgtg tttgcaagat
     3121 caatgaggac tgcaagctcc cgcgctggca catgaacgac ttcttccact ccttcctgat
     3181 agtgttccgc gtgctgtgtg gggagtggat agagaccatg tgggactgca tggaggtcgc
     3241 gggccagacc atgtgcctta ttgtgtttat gttggtcatg gtgattggga accttgtggt
     3301 tctgaacctc ttcctggcct tattgttgag ttcctttagt tcagacaacc ttgctgctac
     3361 ggacgatgat aacgaaatga acaacctcca gatcgcggtg ggaaggatgc aaaaggggat
     3421 tgattatgtg aaaaataaga tacgggagtg cttccgaaaa gcgtttttta gaaagccgaa
     3481 agtgatagaa atccacgaag ggaacaaaat agacagctgc atgtccaata acacgggcgt
     3541 agttgaaata agcaaagagc ttaactacct taaagacggt aacggaacca ccagtggcgt
     3601 gggtactgga agcagtgtgg agaaatacgt aattgatgaa aatgactaca tgtcattcat
     3661 caacaacccc agcctcaccg tgacggtgcc aattgccgtg ggagagtctg actttgaaaa
     3721 tttaaacacg gaagagttta gcagtgagtc agaactggaa gaaagcaagg agaaattaaa
     3781 tgcaaccagc tcttctgaag gaagcacagt tgacgttgct ccgccccgag aaggtgaaca
     3841 agctgaaatt gaacctgagg aggaccttaa gccagaagct tgctttactg aaggatgcat
     3901 taaaaaattt cccttctgcc aagtaagtac ggaagaaggt aaaggaaaaa tctggtggaa
     3961 tcttaggaag acctgctata gcattgtgga acacaactgg tttgagacgt tcattgtgtt
     4021 catgattctc ctcagtagtg gtgctttggc ctttgaagat atatacattg agcaacggaa
     4081 gaccatcaaa accatgctgg agtatgctga caaagtcttc acttacatct tcatcctgga
     4141 aatgctcctc aaatgggtgg cctatggatt tcaaacctat ttcaccaatg cctggtgctg
     4201 gttggacttc ttgattgttg atgtttcttt ggttagcctg gtggccaacg ctcttggcta
     4261 ttcagaactt ggtgccatca aatccctacg gaccctgaga gctctgaggc cgctccgagc
     4321 cttatcccgc tttgaaggca tgagggtggt tgtgaacgct cttgttggtg caatcccctc
     4381 catcatgaat gtgctactgg tgtgcctcat cttctggtta atctttagta tcatgggtgt
     4441 gaatctgttt gctggaaagt tctatcactg tgttaacatg acaacgggca gcatgttcga
     4501 catgagtgaa gtcaacaatt tcagcgactg tcaggctctt ggcaagcaag cccgatggaa
     4561 gaatgtgaaa gtcaactttg acaatgttgg ggctggctac ctggcattgc tgcaagtggc
     4621 cacattcaaa ggctggatgg atattatgta tgcagctgtg gattcacggg acgtcaaact
     4681 gcagcctgta tatgaagaaa atctgtacat gtatctgtac tttgtcatct tcatcatctt
     4741 tgggtcgttc ttcactctaa atctattcat cggcgtcatc atagacaact tcaaccagca
     4801 gaagaagaag tttggaggtc aagacatctt tatgacagaa gagcagaaaa agtactacaa
     4861 tgcaatgaag aaacttggct ccaaaaaacc tcagaagccc atccctcgac ctgcaaacaa
     4921 atttcaagga atggtctttg actttgtaac cagacaagtg tttgacatca gcatcatgat
     4981 cctcatctgc ctcaacatgg tgaccatgat ggtggaaacg gacgaccaga gcaaatacat
     5041 gaccctggtt ttgtcccgaa tcaacctggt attcatcgtc ctcttcactg gggagtttct
     5101 gctgaagctc atctctctca gatactacta cttcacgatt ggctggaaca tctttgactt
     5161 tgtggtggtg attctctcaa ttgtaggaat gttccttgct gagctgatag agaagtattt
     5221 tgtgtctcct accctgttcc gagtcatccg cctggccagg attggacgaa tcctacgcct
     5281 gatcaaaggc gccaagggga tccgcacgct gctctttgct ctgatgatgt cccttcctgc
     5341 gctgttcaac atcggcctcc tgcttttcct cgtcatgttc atctacgcca tctttgggat
     5401 gtccaacttt gcctatgtta aaaaagaggc tggaattgat gacatgttca actttgagac
     5461 ttttggcaac agcatgatct gcctgttcca aatcaccacc tctgcgggct gggatggact
     5521 gttggccccc atcctcaaca gtgcacctcc tgactgtgac cctgatgcaa ttcaccctgg
     5581 aagctcagtg aagggagact gtgggaaccc atctgtgggg attttctttt ttgtcagcta
     5641 catcatcata tccttcctgg ttgtggtgaa catgtacatt gctgtcatcc tggagaactt
     5701 cagcgttgcc acagaagaaa gtgcagagcc cctgagtgag gacgactttg agatgttcta
     5761 cgaggtctgg gagaagttcg accctgacgc cacccagttc atagagttct gcaagctctc
     5821 tgactttgca gctgccctgg atcctcccct cctcatcgca aagccaaaca aagtccagct
     5881 cattgccatg gacctgccca tggtgagtgg agaccgcatc cactgcctgg acatcttatt
     5941 tgcttttaca aagcgggtcc tgggtgagag tggagagatg gatgcccttc gaatccagat
     6001 ggaagatcgg ttcatggctt ccaatccctc caaggtctct tatgagccca ttaccaccac
     6061 tctgaagcgc aaacaagagg aggtgtctgc tgctatcatt cagcgtaatt acagatgtta
     6121 tcttttaaag caaaggttaa aaaacatatc aaatacgtat gacaaagaga caatcaaggg
     6181 gaggattgtc ttgcctataa aaggagatat ggttattgac aaattaaatg ggaattccac
     6241 cccagaaaag acagatggga gttcctctac cacctctcct ccttcctatg acagtgtaac
     6301 aaaaccagat aaggaaaagt ttgagaaaga caaaccagaa aaagaaagca aagggaaaga
     6361 ggtctgagag aatcaaaagt aaaaaaacaa aacaaaaaaa atttcaaaaa tttaaaaagg
     6421 aaacaaagaa atgtctttgt aatcaattgt ttacagcctc tgaaggtaaa gtgtccgtgt
     6481 caactggact ctaaggagag gtccatgcca aactgactgt ttcaacaaat actcaaggtc
     6541 agtgcctata ccagacagtg acctctgtca ctgccactct gtgagacagg gtatcaacat
     6601 tgacaagagg ttgctgcttc cattaccagc tgacactgct gaggggaact ccattgtgaa
     6661 agtgaccgtc atcacgccac caaacaccat tagtacaacc aacgctcctg ttatctattt
     6721 ttaacattca cattgccata tttttacaaa atctgcccca gtgtatcttc ctggtcccca
     6781 cttcatagtc tgttcataat actatgtcac tatttttgta aatgaagtta tgttaaggga
     6841 aaatatatat atatataaat cccatgttgc taagaccaca agtttctcca gtaatcataa
     6901 aaaaaatatt ttgtctgaga gatgaaatta ttgctcaaaa ctaaggaaaa gtaaattcta
     6961 atgttaccac tttgaaatac ttccactttc tggatggtgt tagcttacaa gtgttttagt
     7021 ctgttatgtt tgtatctgag cagttatgtg cctgtaaaga ctcctctaat atttaaagga
     7081 ttatttttat gcaaaatatt ttgtttcaaa aagtgcaaat tttattctaa gtttcagagt
     7141 tctatattta attttagtta aatgtcctcc ctcaaaaaaa aattatctaa tatttctgtt
     7201 ctgaaaaaaa agaaaatcta tccaaagtat caccttagaa tacctgctcc acttactggg
     7261 cagtatttct ttgccatctt ctgctctcag caaaactgac aatttatgtc agttaaatac
     7321 cctctgttat gtaaatagtt attttatcct gtggtgcatg tttgggcaaa tatatataaa
     7381 cgtatatata gcctaataca caaattctat taaatcaaat atgtaccaca gtgtgtgtgt
     7441 gtcctgagca agcttccaac agggaggtgt cctgtatcat tcgttacaca gaaagagttt
     7501 gggaggctat cactaatgca tgctaatatt gcctacgctg ctctatttta atcaatccat
     7561 ttatcacagt tttggtaaga agagtcacat gttggtggta gaatgaattc aatctgctct
     7621 ctgtctacat gtcaaaaaat tctcactgat attaccttaa aacaccttta tttttacatt
     7681 gttaattcaa cttgagtatc ataacgtgtc tttattaatt taaaggagac acactgtata
     7741 gggcctatta ccaaatccta tacttcatag tttgctaaaa aaagaaaaaa aagtccaaaa
     7801 tttgtttaaa tataaataat gtaaaatatc atcagttttc tttgtcaaca tttgtacata
     7861 agaagattat tttcgggtta atgacatggc aatttatttt accttatcct gttgcttctt
     7921 atttttaaat caaaactcca aacttttgca tccaaaagac ttttcaatag ataatttcct
     7981 aaaataaaag ttagacaatg ggttttatgg atttctttgt tataatatat tttctaccat
     8041 cctaataaga gatacgttgg tcaaaatctc aaaccctaac cattttctac caactctggt
     8101 tgcctgcaga gaatccttca ctcatggaag tttgggtttt tttgtttatt ttttgggttt
     8161 tttttttttt aactcaactt ttgtagtatt tgcatatgcg gactaggctt atttttttaa
     8221 atcctgctgc actaaaggta tcatggatct aacacgggct ctgtcctttc taaccaggaa
     8281 ccaagtggga aagttgtgca attgcctaac atgatacaac tcttttctcc tttctcttct
     8341 ttttttcaca aaccaaaagt ttagtgttca ttccttttac aaaactcttc actgtagtat
     8401 actgatgaac tgcatgcagg gaatggcgag ctacttcgtt attgagccaa aagaataaat
     8461 atttcatttt ttttttactg tatctgattt gttggactga gtattttctt ttttaagtta
     8521 tcggcaggta aaaatttaca caactaaaga aaacctgtat ttgattcgac atttgtattc
     8581 atagaagttc acatgggttt tgtaacaccc tgctacacta tctactgaga agtttgtcaa
     8641 aataaagact agttaaaagc a
//
