LOCUS       NM_207262                527 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus secretoglobin, family 2B, member 2 (Scgb2b2), mRNA.
ACCESSION   NM_207262 XM_356005
VERSION     NM_207262.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Lyu,L., Hu,L., Han,L., Zhang,J., Sun,J., Wan,X., Wang,L., Yan,H.
            and Che,C.
  TITLE     Lacrimal androgen-binding proteins protect against Aspergillus
            fumigatus keratitis in mice
  JOURNAL   Int Immunopharmacol 88, 106940 (2020)
   PUBMED   32916626
  REMARK    GeneRIF: Lacrimal androgen-binding proteins protect against
            Aspergillus fumigatus keratitis in mice.
REFERENCE   2  (bases 1 to 527)
  AUTHORS   Ferrero,D.M., Moeller,L.M., Osakada,T., Horio,N., Li,Q., Roy,D.S.,
            Cichy,A., Spehr,M., Touhara,K. and Liberles,S.D.
  TITLE     A juvenile mouse pheromone inhibits sexual behaviour through the
            vomeronasal system
  JOURNAL   Nature 502 (7471), 368-371 (2013)
   PUBMED   24089208
REFERENCE   3  (bases 1 to 527)
  AUTHORS   Jackson,B.C., Thompson,D.C., Wright,M.W., McAndrews,M., Bernard,A.,
            Nebert,D.W. and Vasiliou,V.
  TITLE     Update of the human secretoglobin (SCGB) gene superfamily and an
            example of 'evolutionary bloom' of androgen-binding protein genes
            within the mouse Scgb gene superfamily
  JOURNAL   Hum Genomics 5 (6), 691-702 (2011)
   PUBMED   22155607
  REMARK    Review article
REFERENCE   4  (bases 1 to 527)
  AUTHORS   Laukaitis,C.M., Heger,A., Blakley,T.D., Munclinger,P., Ponting,C.P.
            and Karn,R.C.
  TITLE     Rapid bursts of androgen-binding protein (Abp) gene duplication
            occurred independently in diverse mammals
  JOURNAL   BMC Evol Biol 8, 46 (2008)
   PUBMED   18269759
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 527)
  AUTHORS   Laukaitis,C.M., Dlouhy,S.R., Emes,R.D., Ponting,C.P. and Karn,R.C.
  TITLE     Diverse spatial, temporal, and sexual expression of recently
            duplicated androgen-binding protein genes in Mus musculus
  JOURNAL   BMC Evol Biol 5, 40 (2005)
   PUBMED   16018816
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 527)
  AUTHORS   Ozyildirim,A.M., Wistow,G.J., Gao,J., Wang,J., Dickinson,D.P.,
            Frierson,H.F. Jr. and Laurie,G.W.
  TITLE     The lacrimal gland transcriptome is an unusually rich source of
            rare and poorly characterized gene transcripts
  JOURNAL   Invest Ophthalmol Vis Sci 46 (5), 1572-1580 (2005)
   PUBMED   15851553
REFERENCE   7  (bases 1 to 527)
  AUTHORS   Remington,S.G. and Nelson,J.D.
  TITLE     Secretoglobins: sexually dimorphic expression of androgen-binding
            protein mRNA in mouse lacrimal glands
  JOURNAL   Invest Ophthalmol Vis Sci 46 (1), 31-38 (2005)
   PUBMED   15623751
REFERENCE   8  (bases 1 to 527)
  AUTHORS   Emes,R.D., Riley,M.C., Laukaitis,C.M., Goodstadt,L., Karn,R.C. and
            Ponting,C.P.
  TITLE     Comparative evolutionary genomics of androgen-binding protein genes
  JOURNAL   Genome Res 14 (8), 1516-1529 (2004)
   PUBMED   15256509
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK616217.1 and CK616805.1.
            
            On Jul 27, 2007 this sequence version replaced NM_207262.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY370634.1, CK616638.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-505               CK616217.1         1-505
            506-527             CK616805.1         1-22                c
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 19.32 cM"
     gene            1..527
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /note="secretoglobin, family 2B, member 2"
                     /db_xref="GeneID:381970"
                     /db_xref="MGI:MGI:3042579"
     exon            1..74
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..358
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /note="lacrimal androgen-binding protein epsilon; androgen
                     binding protein epsilon"
                     /codon_start=1
                     /product="secretoglobin family 2B member 2 precursor"
                     /protein_id="NP_997145.2"
                     /db_xref="CCDS:CCDS21128.1"
                     /db_xref="GeneID:381970"
                     /db_xref="MGI:MGI:3042579"
                     /translation="MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHT
                     ELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNI
                     LVKFSKKLTHRS"
     exon            75..256
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /inference="alignment:Splign:2.1.0"
     exon            257..512
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /inference="alignment:Splign:2.1.0"
     regulatory      486..491
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /note="hexamer: AATAAA"
     polyA_site      505
                     /gene="Scgb2b2"
                     /gene_synonym="Abpbg2; Abpbg2p; Abpe; lacrimal"
                     /note="major polyA site"
ORIGIN      
        1 agcactctcc accatgaagg ggacacttct tctgctggcc ttgctggtga ctggagagct
       61 gggcttccag agaacggaag catgcatacc tttcttcggc gtatatttgg gtattctctc
      121 tggaaacagg attgggttac atacagaact tgctccattt gatcctactg tggaggaaaa
      181 ggaggctttt gaaaaaatcc aggactgcta tgaggaggaa ggactaaaag ctaagactga
      241 agatatgaaa ttgatgacaa ctatactctt cagctcagaa tgcaggtcgt actataccaa
      301 agaagtcttg aagaacattc tggttaagtt ttccaagaaa ttaacccata gaagttaatg
      361 ggttatacgc aacccatctt tgcaatgtgt ctgatctgag tgccatcttg ctgacctttc
      421 tttctctctg taagttggat tcctgacacc tgtgccttca tcctttagtc tcttaggctg
      481 attctaataa atgcctgcag ctctgttcag tgaaaaaaaa aaaaaaa
//
