LOCUS       NM_011681                468 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus secretoglobin, family 1A, member 1 (Scgb1a1), mRNA.
ACCESSION   NM_011681
VERSION     NM_011681.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Warren,R., Klinkhammer,K., Lyu,H., Knopp,J., Yuan,T., Yao,C.,
            Stripp,B. and De Langhe,S.P.
  TITLE     Cell competition drives bronchiolization and pulmonary fibrosis
  JOURNAL   Nat Commun 15 (1), 10624 (2024)
   PUBMED   39639058
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Xu,L., Tan,C., Barr,J., Talaba,N., Verheyden,J., Chin,J.S.,
            Gaboyan,S., Kasaraneni,N., Elgamal,R.M., Gaulton,K.J., Lin,G.,
            Afshar,K., Golts,E., Meier,A., Crotty Alexander,L.E., Borok,Z.,
            Shen,Y., Chung,W.K., McCulley,D.J. and Sun,X.
  TITLE     Context-dependent roles of mitochondrial LONP1 in orchestrating the
            balance between airway progenitor versus progeny cells
  JOURNAL   Cell Stem Cell 31 (10), 1465-1483 (2024)
   PUBMED   39181129
REFERENCE   3  (bases 1 to 468)
  AUTHORS   Lingamallu,S.M., Deshpande,A., Joy,N., Ganeshan,K., Ray,N.,
            Ladher,R.K., Taketo,M.M., Lafkas,D. and Guha,A.
  TITLE     Neuroepithelial bodies and terminal bronchioles are niches for
            distinctive club cells that repair the airways following acute
            notch inhibition
  JOURNAL   Cell Rep 43 (9), 114654 (2024)
   PUBMED   39182223
REFERENCE   4  (bases 1 to 468)
  AUTHORS   He,H., Bell,S.M., Davis,A.K., Zhao,S., Sridharan,A., Na,C.L.,
            Guo,M., Xu,Y., Snowball,J., Swarr,D.T., Zacharias,W.J. and
            Whitsett,J.A.
  TITLE     PRDM3/16 regulate chromatin accessibility required for NKX2-1
            mediated alveolar epithelial differentiation and function
  JOURNAL   Nat Commun 15 (1), 8112 (2024)
   PUBMED   39284798
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 468)
  AUTHORS   Xu,Y.D., Cheng,M., Mao,J.X., Zhang,X., Shang,P.P., Long,J.,
            Chen,Y.J., Wang,Y., Yin,L.M. and Yang,Y.Q.
  TITLE     Clara cell 10 (CC10) protein attenuates allergic airway
            inflammation by modulating lung dendritic cell functions
  JOURNAL   Cell Mol Life Sci 81 (1), 321 (2024)
   PUBMED   39078462
  REMARK    GeneRIF: Clara cell 10 (CC10) protein attenuates allergic airway
            inflammation by modulating lung dendritic cell functions.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 468)
  AUTHORS   Ray,M.K., Magdaleno,S.W., Finegold,M.J. and DeMayo,F.J.
  TITLE     cis-acting elements involved in the regulation of mouse Clara
            cell-specific 10-kDa protein gene. In vitro and in vivo analysis
  JOURNAL   J Biol Chem 270 (6), 2689-2694 (1995)
   PUBMED   7852338
REFERENCE   7  (bases 1 to 468)
  AUTHORS   Stripp,B.R., Huffman,J.A. and Bohinski,R.J.
  TITLE     Structure and regulation of the murine Clara cell secretory protein
            gene
  JOURNAL   Genomics 20 (1), 27-35 (1994)
   PUBMED   8020953
REFERENCE   8  (bases 1 to 468)
  AUTHORS   Ray,M.K., Magdaleno,S., O'Malley,B.W. and DeMayo,F.J.
  TITLE     Cloning and characterization of the mouse Clara cell specific 10
            kDa protein gene: comparison of the 5'-flanking region with the
            human rat and rabbit gene
  JOURNAL   Biochem Biophys Res Commun 197 (1), 163-171 (1993)
   PUBMED   7916613
REFERENCE   9  (bases 1 to 468)
  AUTHORS   Margraf,L.R., Finegold,M.J., Stanley,L.A., Major,A., Hawkins,H.K.
            and DeMayo,F.J.
  TITLE     Cloning and tissue-specific expression of the cDNA for the mouse
            Clara cell 10 kD protein: comparison of endogenous expression to
            rabbit uteroglobin promoter-driven transgene expression
  JOURNAL   Am J Respir Cell Mol Biol 9 (3), 231-238 (1993)
   PUBMED   8398159
REFERENCE   10 (bases 1 to 468)
  AUTHORS   Sandmoller,A., Voss,A.K., Hahn,J., Redemann-Fibi,B., Suske,G. and
            Beato,M.
  TITLE     Cell-specific, developmentally and hormonally regulated expression
            of the rabbit uteroglobin transgene and the endogenous mouse
            uteroglobin gene in transgenic mice
  JOURNAL   Mech Dev 34 (1), 57-67 (1991)
   PUBMED   1911394
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB595042.1 and AK145844.1.
            
            On Mar 24, 2007 this sequence version replaced NM_011681.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB596926.1, CB595042.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                CB595042.1         5-40
            37-468              AK145844.1         2-433
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 6.05 cM"
     gene            1..468
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /note="secretoglobin, family 1A, member 1"
                     /db_xref="GeneID:22287"
                     /db_xref="MGI:MGI:98919"
     exon            1..110
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..346
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /note="CCPBP; PCB-binding protein; uteroglobin;
                     Blastokinin; club cell secretory protein; club cells 10
                     kDa secretory protein; club cell 17 kDa protein; club cell
                     phospholipid-binding protein"
                     /codon_start=1
                     /product="uteroglobin precursor"
                     /protein_id="NP_035811.1"
                     /db_xref="CCDS:CCDS37911.1"
                     /db_xref="GeneID:22287"
                     /db_xref="MGI:MGI:98919"
                     /translation="MKIAITITVVMLSICCSSASSDICPGFLQVLEALLMESESGYVA
                     SLKPFNPGSDLQNAGTQLKRLVDTLPQETRINIMKLTEKILTSPLCKQDLRF"
     exon            111..298
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /inference="alignment:Splign:2.1.0"
     exon            299..468
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /inference="alignment:Splign:2.1.0"
     regulatory      450..455
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /note="putative"
     polyA_site      468
                     /gene="Scgb1a1"
                     /gene_synonym="CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg"
                     /note="putative"
ORIGIN      
        1 cacacattac aacatcaccc cacatctaca gacaccaaag cctccaacct ctaccatgaa
       61 gatcgccatc acaatcactg tggtcatgct gtccatctgc tgcagctcag cttcttcgga
      121 catctgccca ggatttcttc aagtccttga ggccctcctc atggaatcag agtctggtta
      181 tgtggcatcc ctgaagcctt tcaaccctgg ctcagacctg caaaatgcgg gcacccagct
      241 gaagagactg gtggataccc tcccacaaga gaccaggata aacatcatga agctcacgga
      301 gaaaatccta acaagtcctc tgtgtaagca agatttaaga ttctgaagct cactggattt
      361 cagagatatt ctactgctaa agccttgtca ctgccctgtg tctcctcggc tcctcggctt
      421 ccccacacca acccctcctt cctctttgca ataaactgcg agcatctc
//
