LOCUS       NM_022886               3053 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus sciellin (Scel), mRNA.
ACCESSION   NM_022886
VERSION     NM_022886.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3053)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3053)
  AUTHORS   Baden,H.P., Champliaud,M.F., Sundberg,J.P. and Viel,A.
  TITLE     Targeted deletion of the sciellin gene resulted in normal
            development and maturation
  JOURNAL   Genesis 42 (4), 219-228 (2005)
   PUBMED   16028229
  REMARK    GeneRIF: We conclude that sciellin null mice had no structural
            anomalies and the transgenic mice did not act as a
            dominant-negative mutation.
REFERENCE   3  (bases 1 to 3053)
  AUTHORS   Burgess,R.W., Peterson,K.A., Johnson,M.J., Roix,J.J., Welsh,I.C.
            and O'Brien,T.P.
  TITLE     Evidence for a conserved function in synapse formation reveals Phr1
            as a candidate gene for respiratory failure in newborn mice
  JOURNAL   Mol Cell Biol 24 (3), 1096-1105 (2004)
   PUBMED   14729956
REFERENCE   4  (bases 1 to 3053)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   5  (bases 1 to 3053)
  AUTHORS   Peterson,K.A., King,B.L., Hagge-Greenberg,A., Roix,J.J., Bult,C.J.
            and O'Brien,T.P.
  TITLE     Functional and comparative genomic analysis of the piebald deletion
            region of mouse chromosome 14
  JOURNAL   Genomics 80 (2), 172-184 (2002)
   PUBMED   12160731
REFERENCE   6  (bases 1 to 3053)
  AUTHORS   Champliaud,M.F., Baden,H.P., Koch,M., Jin,W., Burgeson,R.E. and
            Viel,A.
  TITLE     Gene characterization of sciellin (SCEL) and protein localization
            in vertebrate epithelia displaying barrier properties
  JOURNAL   Genomics 70 (2), 264-268 (2000)
   PUBMED   11112355
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY775767.1, AF245700.2 and AC125201.4.
            
            On Jul 16, 2005 this sequence version replaced NM_022886.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF245700.2, BC111874.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-166               BY775767.1         2-167
            167-2296            AF245700.2         167-2296
            2297-3053           AC125201.4         123270-124026
FEATURES             Location/Qualifiers
     source          1..3053
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 52.51 cM"
     gene            1..3053
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /note="sciellin"
                     /db_xref="GeneID:64929"
                     /db_xref="MGI:MGI:1891228"
     exon            1..128
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            129..190
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..2106
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /codon_start=1
                     /product="sciellin"
                     /protein_id="NP_075024.2"
                     /db_xref="CCDS:CCDS37002.1"
                     /db_xref="GeneID:64929"
                     /db_xref="MGI:MGI:1891228"
                     /translation="MSNFSSRKKSPTGNDLKSARGAELRQQGFQDVNKRRAFLQDNSW
                     IKKPPEEEQDGNYGRVVLNRHNSHDALDRKLIERDEPKATISRYRSEDMLDRTLSSFR
                     TPQSTKTPAVSSFNANTTATASTPATTPVKKKRQSWFPPPPPGHNASPSTAASRRDPA
                     LHPPLPPKPCSPIASPKPLGRTNRQIHAATAGACGETERHAERNIRTEDLDDIIRVAA
                     ALQKTDKGEELDNLIRMNKSLNRNQGLDGLFRANLKAQQLDKRAQSLESLIYMNTQTD
                     RDGKGNQAFGSLKKINQRADPDRRSQDLRSVIRTHATAERIGRRKQDLDGLIKVNPDT
                     NKNMKRGKSLDNLIKVTPEVNRSNKGGPSLDNFTKGVPARSRANQRDQDLDSLIKVTP
                     SANRSSQHSLDELINTSPQTIKTTARHQDLDKFIKVNPDVLTNNQRNHDVDSTIRGNP
                     TGTRCEQSEELDNLIKVKPSALRNTNGGQDLESLTEVNSHVAEKNGRIDGQANGLTNS
                     LFKESTRASVYSYEARNSLSSNSGNKNGGPKDTVVYTRTYVENSKSPKDGYQENISGK
                     YIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKRPLENL
                     QAGDSIWIYRQTIHCEPCYSKVMAKWIQ"
     exon            191..305
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            306..365
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            366..434
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            435..473
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            474..551
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            552..617
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            618..698
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            699..764
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            765..824
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            825..869
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            870..929
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            930..989
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1046
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1106
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1166
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1226
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1286
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1337
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1400
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1460
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1520
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1577
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1637
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1730
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1731..1802
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..1877
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..1986
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1987..2089
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..3053
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3032..3037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3053
                     /gene="Scel"
                     /gene_synonym="9230114I02Rik"
                     /note="major polyA site"
ORIGIN      
        1 attaacaggc gagcggaggt gggaagtgca cccaggaagc gccaggtgca catttgtttc
       61 agccggatcc acttggggaa tcactgcggg ccagttagcc aagagtcccg ggttcctgcg
      121 caagaaagat cctcactaga atccagcatg tcaaattttt cctctagaaa aaagtctcca
      181 actggaaatg atctgaagag cgcccgggga gctgagctga gacaacaggg ttttcaggac
      241 gtgaacaaaa gaagggcttt cttacaggac aacagctgga taaagaagcc cccagaggaa
      301 gaacaagacg gaaattatgg cagggtggtg ctcaaccggc acaactccca tgatgccttg
      361 gacaggaaat taatagagag agatgagcca aaagccacaa ttagccggta cagatctgag
      421 gacatgctgg acagaacact gtcctcattt agaacgccac aatcaaccaa gacgccagct
      481 gtcagctcct tcaatgcaaa cactaccgcc acagcttcaa cccccgctac cactcctgtg
      541 aagaaaaaga gacagtcctg gttcccacca ccccctcctg gtcacaatgc ctctccaagc
      601 acagcagcca gcagaaggga cccagctctg caccctccac tccccccaaa gccctgttct
      661 cccattgctt ctcctaaacc attggggcgg actaataggc agatacatgc agctacagcg
      721 ggggcatgtg gagaaacaga acgacatgct gaaagaaata taaggactga ggatctcgat
      781 gacatcatca gggtggcggc tgcacttcag aaaactgaca agggtgaaga attggataat
      841 ctcatcagaa tgaacaaaag cttgaacaga aaccaaggtc tcgatggcct cttccgagca
      901 aacctgaagg cacagcaatt ggacaaaaga gcccagagtc ttgaaagcct gatctatatg
      961 aacacacaga cggacagaga tggcaaagga aatcaagcct tcgggagcct taagaaaatc
     1021 aaccaaaggg ctgaccccga cagaagaagc caagatctca gatcagttat cagaacacat
     1081 gccacggctg agagaatcgg cagaagaaaa caagacctcg atggactgat taaagtgaat
     1141 cctgacacaa ataaaaatat gaagaggggc aagagccttg acaatcttat caaagtcacc
     1201 ccggaagtaa acagaagcaa caaagggggt ccaagtcttg acaatttcac caaaggagtt
     1261 cctgcaagga gcagagctaa ccaaagggac caagacctgg acagtcttat caaggtgacc
     1321 ccctcagcaa acagaagcag ccagcacagt cttgatgaac ttattaatac aagcccccaa
     1381 actatcaaaa ctactgctag acaccaagat ctcgataagt tcatcaaagt aaatcctgat
     1441 gttctcacaa acaaccaaag aaaccatgat gtagacagca ccatcagagg gaatcctaca
     1501 gggaccagat gcgagcaaag cgaagagttg gacaatctta tcaaagtgaa gccttctgct
     1561 ctcagaaaca caaatggagg ccaggaccta gaaagcttaa ctgaagtaaa ttctcatgtg
     1621 gctgagaaga atgggaggat agatggccaa gccaatggat tgactaacag tctgttcaag
     1681 gagtccacaa gagcctcggt ctattcttat gaagccagaa acagtctcag ctccaattct
     1741 ggaaacaaga atggtggacc caaggacact gttgtttata caaggacata tgtggagaac
     1801 agtaaatcac caaaggatgg ttatcaggaa aatatctcag gaaaatatat acaaaccgtt
     1861 tattcaactt cagataggtc tgtcattgaa agagacatgt gcacttactg ccgcaagccc
     1921 ttgggggtgg aaaccaagat gattttagat gaattacaga tctgttgcca ttccacctgc
     1981 tttaagtgtg aaatatgcaa acggcctctg gaaaatttac aggcaggaga cagtatttgg
     2041 atctataggc agacgataca ctgtgagccc tgctactcta aagtgatggc aaaatggatt
     2101 cagtaacgcc gacacgtgga aatgaagatg agcaccttca tcgaggaatt taaagctaca
     2161 tttaagaata tgtaatctag aaaacatctg cattggacat catctcttga atcaaaataa
     2221 cagttttgtt gttgcacaaa caatctaatt acattgaaga aggtcacata tgtgaaaaga
     2281 atcatctggt gtctggcaaa gtttagtgat aaaaaaaaat ctacatagtt ctagttacca
     2341 aactcaacgg cagtgagcat tctcaaccct gagcaggcca tctctgctct atatttgact
     2401 gtccatcttg gtttccattt taactgagtt tcttatcttc ctacctacat ccctctaata
     2461 atttgcatta gagcattatt gaccccctga caaataggct gctggaagca agatatactt
     2521 cttttttcta caaaagaaaa tgcacataga aatttccttc taaatttttg gttcaaggta
     2581 tcaatgttcc aagttgtttg gaccttagaa aaatcactta aaatttccag actttctgtg
     2641 gcattatcta tgacaacaca gatattagac aaaatggttt ctaagtccct ccttgctttt
     2701 cctatcctct gaatctaaaa gagatttgag tttcctgttt agaaacatgt tggtatattt
     2761 gttagctatg ttgggaaata taaataattt cacctaagtg tcacccttca gtttatcaca
     2821 ggcatggctt ttgaggacta ttcttaaaac tggaatcaat agctctatgg gtgataggta
     2881 aaaatcagat aacgtgtaat ttgttaaact ttctttgcat gtatttcaaa atctgggtga
     2941 tcaaataatc tgagaagtaa tagctatgta ttgcaaacac gttatgtaag ttcgtgttat
     3001 aaacagttta tgtttacaga aggatcacaa caataaaatg aactgtcaat ttc
//
