LOCUS       NM_172909               3454 bp    mRNA    linear   ROD 29-AUG-2024
DEFINITION  Mus musculus scavenger receptor family member expressed on T cells
            1 (Scart1), mRNA.
ACCESSION   NM_172909 XM_620583
VERSION     NM_172909.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3454)
  AUTHORS   Fink,D.R., Holm,D., Schlosser,A., Nielsen,O., Latta,M., Lozano,F.
            and Holmskov,U.
  TITLE     Elevated numbers of SCART1+ gammadelta T cells in skin inflammation
            and inflammatory bowel disease
  JOURNAL   Mol Immunol 47 (9), 1710-1718 (2010)
   PUBMED   20381152
  REMARK    GeneRIF: Results show that SCART1 is a novel gammadelta T cell
            marker and it is therefore likely that SCART1 plays a role in the
            immune response.
REFERENCE   2  (bases 1 to 3454)
  AUTHORS   Holm,D., Fink,D.R., Gronlund,J., Hansen,S. and Holmskov,U.
  TITLE     Cloning and characterization of SCART1, a novel scavenger receptor
            cysteine-rich type I transmembrane molecule
  JOURNAL   Mol Immunol 46 (8-9), 1663-1672 (2009)
   PUBMED   19297026
  REMARK    GeneRIF: mSCART1 is highly related to the WC1 family of the SRCR
            superfamily.
REFERENCE   3  (bases 1 to 3454)
  AUTHORS   Kisielow,J., Kopf,M. and Karjalainen,K.
  TITLE     SCART scavenger receptors identify a novel subset of adult
            gammadelta T cells
  JOURNAL   J Immunol 181 (3), 1710-1716 (2008)
   PUBMED   18641307
  REMARK    GeneRIF: described two novel surface receptors, SCART1 and SCART2
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107839.14.
            
            On Apr 17, 2007 this sequence version replaced NM_172909.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849375
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-362               AC107839.14        153736-154097       c
            363-695             AC107839.14        151660-151992       c
            696-989             AC107839.14        149914-150207       c
            990-1298            AC107839.14        148840-149148       c
            1299-1604           AC107839.14        148168-148473       c
            1605-1922           AC107839.14        147727-148044       c
            1923-2237           AC107839.14        147340-147654       c
            2238-2555           AC107839.14        144190-144507       c
            2556-2624           AC107839.14        143934-144002       c
            2625-2939           AC107839.14        143546-143860       c
            2940-2963           AC107839.14        143306-143329       c
            2964-3101           AC107839.14        142482-142619       c
            3102-3277           AC107839.14        141889-142064       c
            3278-3454           AC107839.14        141219-141395       c
FEATURES             Location/Qualifiers
     source          1..3454
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 85.26 cM"
     gene            1..3454
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /note="scavenger receptor family member expressed on T
                     cells 1"
                     /db_xref="GeneID:244233"
                     /db_xref="MGI:MGI:2443796"
     exon            1..362
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..3268
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /note="scavenger receptor cysteine-rich type 1 protein
                     CD163c-alpha; CD163 molecule-like 1"
                     /codon_start=1
                     /product="scavenger receptor cysteine-rich
                     domain-containing protein SCART1 precursor"
                     /protein_id="NP_766497.3"
                     /db_xref="CCDS:CCDS40174.1"
                     /db_xref="GeneID:244233"
                     /db_xref="MGI:MGI:2443796"
                     /translation="MRTTLWPLSLGSLLTLGAALTGTSSEGDQGNLRLAHRQSTCDGV
                     VLVRHQGEWGHLCNLEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMVRPWLHNVSCW
                     GNESSLWECSLGAWSQRACPHEWVVVALCANGTFREIRLVKGHSPCAGLPEIMNVNGV
                     DRLCGLHVEEATVFCRELQCGHALQAPRQDVGVSKYMTCKGTESTIRNCRLNNKLRGG
                     CNLLLDAEVICSGHVEARLVGGEHSCAGRLEVLRGLTWGTICHADLDLPTAHVVCREL
                     GCGIAVSTLGGAQFGQGSGPVWLEAFRCVGNESLLFHCPREPGHHCGHEQDAALTCSE
                     FRLVNGSSDCEGRVELQVQGTWAPVCAANWDLADAMVLCHQLNCGNAVSVPPGGHFGD
                     GDDLIWPDIFHCVGTEPHLLHCAASTLGAHGCVLGNTASTICSGLQDILRLRDGQSYC
                     DGRVEISLDGSWGRVLDDAWDLHGASVVCRQLGCGEAQRAYDAPAPIFRRVPVGLSQV
                     RCLGSETRLVHCNVSTSLLVPAGTLRDAGVVCSGSLRVRLAAGPGRCAGRVELFYQGS
                     WGTVCDDAWDLQDAQVVCRQLDCGHALSAPRNAHFGAGTGHIWMDELHCLGNESSLWK
                     CQSGSWGQHDCRHKEDAGVFCSESVALRLRGGTSGCVGWLDVLYNGSWGAVCSNALRD
                     ISLSIICRQLGCGDQGWLENRPSSGAGLGISWVDNIKCRNLHNATLWQCPSAPWNPHS
                     CTQEEEVWINCEGTPQIALQDPAQTPNCSSPFGCLENSVLRVLGGEDGCSGRVELWHA
                     GSWGTVCDDSWDLVDAEVVCRQLGCGQALAALGEASFGPGVGPVWLDEVECLGSEVTL
                     EACQAEPWGHGDCTHKEDAGVRCAGVSTTTALSPSLTPPSVAEVWKLSEIACLVLGCL
                     LGIVFLVMIAQWCHIRDASMGAGMLGHLQSEGIYEDIEVDPVPKKEENTVSRLLMLEE
                     GYDDAEEPEDQPTENDE"
     exon            363..695
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            696..989
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1298
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1604
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1922
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..2237
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2555
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2556..2624
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2625..2939
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2940..2963
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2964..3101
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3102..3277
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..3454
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3430..3435
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3451
                     /gene="Scart1"
                     /gene_synonym="B430307C05; Cd163l1; E430002D04Rik"
                     /note="major polyA site"
ORIGIN      
        1 actctgtgaa agacaggcca cctgtctggt ggcagggtct gggtgaggct ctccttcagt
       61 ggttatcagt atgggaggaa accaccccag cctcttgttc atgtctggtg gtgctcagga
      121 ccagcaagga cattgactgc tctgccacag acggagacgt agagctgctg atgtgccgtg
      181 gagaggctct tactgtatgc atcggacaca ggctaatggt tctcttacat ctataaaatt
      241 ggctctggga cgagatctcc tttatcgctg cagctgaggc tctggacttc gtgcggccat
      301 gaggacaacg ctctggcctc tgagtttagg gtctcttctc actctcgggg cagctctcac
      361 tggcacatca tctgaaggtg accaaggcaa tctgaggctg gcacacagac agagcacatg
      421 tgacggagtg gtgctggttc gacaccaagg ggaatggggt cacctgtgca acctggagtg
      481 gacactggca gaggcctctg tggtgtgtag acagctgggc tgtggccctg ctgtgggtgc
      541 tcccaaatat gtacccctgc ctggagagat ggtccggccc tggctgcaca atgtatcctg
      601 ttggggcaat gagtcctctc tctgggagtg tagccttggg gcatggagtc agcgtgcttg
      661 cccccatgag tgggtggtgg tggctctctg tgcaaatggc accttccggg agatccggct
      721 ggtgaagggc cacagtccct gtgcaggact ccctgagatc atgaatgtga atggggtgga
      781 ccgcctctgt ggcctgcatg tggaggaggc cacagtgttt tgccgtgagc tgcagtgtgg
      841 ccatgcactc caggcccccc gtcaagatgt gggcgtcagt aagtacatga cctgcaaggg
      901 caccgagtcc accatccgca actgcagact caacaacaag ctacgcggtg gctgcaacct
      961 gctgctggat gcagaagtca tctgctcagg acacgtggag gcccggctag tgggtggaga
     1021 acattcctgt gctggacgcc tggaggttct tcggggactg acctggggta ccatctgcca
     1081 tgctgatctg gacttgccca cagcccatgt ggtgtgccgg gagttagggt gtggtatagc
     1141 tgtgtctaca cttgggggtg ctcagtttgg ccagggctca ggacctgtgt ggctagaagc
     1201 cttccgctgt gtggggaatg aatcgctgct attccactgc ccccgggagc ccggtcacca
     1261 ctgtggccac gagcaggatg ctgcactcac ctgctcagag ttccggctgg tcaatggcag
     1321 cagtgactgt gaaggccgtg tggaactcca agtgcaaggg acctgggcac ctgtctgtgc
     1381 tgccaactgg gacctagcag atgccatggt tctctgtcac caactcaact gtggcaatgc
     1441 agtatctgta cctccaggag gacattttgg tgatggggat gatctcatct ggccagacat
     1501 atttcattgt gtggggacag agcctcattt gcttcactgt gcagcaagca ccctgggggc
     1561 ccatggttgt gtcctgggga atacagcttc taccatctgt tcaggactcc aagacatcct
     1621 gcggctgaga gatggacaga gctactgtga tggccgtgta gagatttccc tggatggttc
     1681 atggggccgc gtattggatg acgcctggga cctgcatggc gccagcgtgg tgtgccggca
     1741 gctagggtgt ggagaggcac agcgagccta tgatgctcca gctcctattt tcaggagagt
     1801 ccctgtgggg ctgagccagg tgcgctgcct gggctctgag actcgcctgg tgcattgcaa
     1861 tgtttctacg tccctgctgg tgcctgctgg gaccttgcgt gacgcaggag tggtgtgctc
     1921 cgggagcctg cgcgtgaggc tggctgcggg cccaggtcga tgtgctgggc gtgtggagtt
     1981 attctatcag ggctcctggg gcactgtgtg tgatgatgcc tgggacctac aggatgcaca
     2041 agtggtctgt aggcagctgg actgtggcca cgccctcagt gctccccgga atgctcactt
     2101 tggggcgggg actgggcaca tctggatgga tgagctgcac tgcttgggaa atgagtcttc
     2161 gttgtggaag tgccagtcag gaagctgggg ccaacatgac tgcagacaca aggaggatgc
     2221 tggagtgttc tgctcagaat ctgtggctct gaggcttcga ggtggcacta gtggctgcgt
     2281 tggatggctg gacgtgctct acaatgggtc ctggggtgct gtgtgcagca atgcactcag
     2341 agacatctcc ttgagcatca tctgcagaca gctgggatgt ggggaccagg gctggctgga
     2401 gaacaggcct tcttctggag ctggcctggg aatctcctgg gtggataata tcaagtgtcg
     2461 aaatctacac aatgccaccc tgtggcaatg cccttctgcc ccatggaacc cgcactcctg
     2521 cacccaggag gaggaggtct ggattaactg tgaaggaaca ccacagatag ctctccagga
     2581 ccctgcacag accccaaact gctcttctcc atttggctgc ctagagaaca gtgttctgcg
     2641 tgtgcttggg ggtgaggatg gctgttccgg gcgtgtggag ctctggcacg caggctcatg
     2701 gggcacagtg tgtgacgact cctgggacct ggtggatgcc gaggttgtgt gccggcaact
     2761 gggctgcggc caggccttgg ctgctttagg agaggcttcc tttggccctg gtgtggggcc
     2821 tgtgtggctg gatgaggtcg agtgccttgg cagtgaggtg accctggagg cctgccaggc
     2881 tgagccctgg ggacatggag actgcacgca caaggaggat gcaggtgttc gctgtgcggg
     2941 tgtctccacg accactgcat tgtctccttc cctgacccct ccatcggttg ccgaggtctg
     3001 gaaactgtcg gagattgcct gcttggtgct tggctgcctt ctgggcattg tcttcctggt
     3061 tatgattgct cagtggtgcc acatcagaga tgctagcatg ggtgctggca tgttggggca
     3121 tctacagtca gaaggtatct atgaggacat tgaagttgac cctgtgccaa agaaggagga
     3181 gaacacagta tccaggctac tgatgctgga agagggttat gatgatgctg aagagcctga
     3241 ggatcagccc acagagaatg acgagtagaa taggcactcg ggagtctttg cagctcagtg
     3301 ctgaggctgg gaaggaagac tatggtagtt cctgtcctga cacttgatgc ctttgctgac
     3361 cttaggggtc acaagactat cctattcctg ggagactaag gactagccct cttttattaa
     3421 gtaaatgtta ttaaactttg aattcacagt tcaa
//
